ATE184294T1 - Poly-3-hydroxyalkanoate und verfahren zu ihrer herstellung - Google Patents

Poly-3-hydroxyalkanoate und verfahren zu ihrer herstellung

Info

Publication number
ATE184294T1
ATE184294T1 AT93915222T AT93915222T ATE184294T1 AT E184294 T1 ATE184294 T1 AT E184294T1 AT 93915222 T AT93915222 T AT 93915222T AT 93915222 T AT93915222 T AT 93915222T AT E184294 T1 ATE184294 T1 AT E184294T1
Authority
AT
Austria
Prior art keywords
poly
hydroxyalkanoates
production
substituted
integer
Prior art date
Application number
AT93915222T
Other languages
English (en)
Inventor
John Clark Hubbs
Marti Noel Harrison
Steve Carl Gedon
Charles Michael Buchanan
Robert Marshall Gardner
Douglas Claire Hoffman
Alan Wayne White
Original Assignee
Eastman Chem Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eastman Chem Co filed Critical Eastman Chem Co
Application granted granted Critical
Publication of ATE184294T1 publication Critical patent/ATE184294T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C08G63/08—Lactones or lactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/04—Polyesters derived from hydroxycarboxylic acids, e.g. lactones
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/78—Preparation processes
    • C08G63/82—Preparation processes characterised by the catalyst used
    • C08G63/823—Preparation processes characterised by the catalyst used for the preparation of polylactones or polylactides
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L101/00—Compositions of unspecified macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L67/00—Compositions of polyesters obtained by reactions forming a carboxylic ester link in the main chain; Compositions of derivatives of such polymers
    • C08L67/02—Polyesters derived from dicarboxylic acids and dihydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L2201/00—Properties
    • C08L2201/06—Biodegradable

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Polyamides (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT93915222T 1992-06-19 1993-06-07 Poly-3-hydroxyalkanoate und verfahren zu ihrer herstellung ATE184294T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/901,306 US5281691A (en) 1992-06-19 1992-06-19 Poly(3-hydroxyalkanoates)

Publications (1)

Publication Number Publication Date
ATE184294T1 true ATE184294T1 (de) 1999-09-15

Family

ID=25413909

Family Applications (2)

Application Number Title Priority Date Filing Date
AT93915222T ATE184294T1 (de) 1992-06-19 1993-06-07 Poly-3-hydroxyalkanoate und verfahren zu ihrer herstellung
AT98124234T ATE250645T1 (de) 1992-06-19 1993-06-07 Zusammensetzung die poly(3-hydroxyalkanoate) enthält

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT98124234T ATE250645T1 (de) 1992-06-19 1993-06-07 Zusammensetzung die poly(3-hydroxyalkanoate) enthält

Country Status (12)

Country Link
US (4) US5281691A (de)
EP (2) EP0648238B1 (de)
JP (1) JPH08500131A (de)
KR (1) KR950702221A (de)
AT (2) ATE184294T1 (de)
CA (1) CA2138034C (de)
DE (2) DE69333220T2 (de)
DK (1) DK0648238T3 (de)
ES (1) ES2135482T3 (de)
GR (1) GR3031600T3 (de)
MX (1) MX9303692A (de)
WO (1) WO1994000506A1 (de)

Families Citing this family (82)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939467A (en) * 1992-06-26 1999-08-17 The Procter & Gamble Company Biodegradable polymeric compositions and products thereof
JP3473910B2 (ja) * 1992-10-07 2003-12-08 ノボン・インターナショナル・インコーポレーテッド デンプンエステルの線状ポリエステルとの混合物
GB9223351D0 (en) * 1992-11-06 1992-12-23 Ici Plc Polyesters
JP3098350B2 (ja) * 1993-02-26 2000-10-16 高砂香料工業株式会社 ポリ（３−ヒドロキシ酪酸）の製造方法
AU703156B2 (en) * 1994-01-28 1999-03-18 Procter & Gamble Company, The Biodegradable copolymers and plastic articles comprising biodegradable copolymers of 3-hydroxyhexanoate
EP1375556A3 (de) * 1994-01-28 2004-08-11 The Procter & Gamble Company Bioabbaubare Copolymere und Kunststoffgegenstände die bioabbaubare 3-Hydroxyhexanoatcopolymere enthalten
ZA95627B (en) * 1994-01-28 1995-10-05 Procter & Gamble Biodegradable copolymers and plastic articles comprising biodegradable copolymers
ID23491A (id) * 1994-01-28 1995-09-07 Procter & Gamble Kopolimer-kopolimer yang dapat dibiodegradasi dan baha-bahan plastik yang terdiri dari kopolimer-kopolimer yang dapat dibiodegradasi
SG49096A1 (en) * 1994-01-28 1998-05-18 Procter & Gamble Biodegradable 3-polyhydtoxybuyrate/3- polyhydroxyhexanoate copolymer films
US5780368A (en) * 1994-01-28 1998-07-14 Noda; Isao Spray processes using a gaseous flow for preparing biodegradable fibrils, nonwoven fabrics comprising biodegradable fibrils, and articles comprising such nonwoven fabrics
JPH10501134A (ja) * 1994-06-01 1998-02-03 ザ、プロクター、エンド、ギャンブル、カンパニー 遠心分別を用いてポリヒドロキシアルカノエートを回収するためのプロセス
CN1079835C (zh) * 1994-06-01 2002-02-27 普罗克特和甘保尔公司 利用空气分级作用回收聚羟基链烷酸酯的方法
US5563239A (en) * 1994-11-09 1996-10-08 Eastman Chemical Company Composition and process for the production of poly(3-hydroxyalkanoates)
JP3667812B2 (ja) * 1995-02-28 2005-07-06 グンゼ株式会社 養殖用網
US5786408A (en) * 1995-06-22 1998-07-28 Daicel Chemical Industries, Ltd. Biodegradable polyester resin composition, and a biodegradable molded article
US5942597A (en) * 1995-08-21 1999-08-24 The Procter & Gamble Company Solvent extraction of polyhydroxyalkanoates from biomass
US6143947A (en) * 1996-01-29 2000-11-07 The Procter & Gamble Company Fibers, nonwoven fabrics and absorbent articles comprising a biodegradable polyhydroxyalkanoate comprising 3-hydroxybutyrate and 3-hydroxyhexanoate
US6156852A (en) 1997-04-21 2000-12-05 Monsanto Company Hydroxy-terminated polyhydroxyalkanoates
US5844654A (en) * 1997-05-28 1998-12-01 Shimadzu Corporation Biodegradable resin for forming spectacle-molded body and spectacle-molded body
JP3201739B2 (ja) * 1997-05-28 2001-08-27 株式会社島津製作所 眼鏡成形体
DE69841061D1 (de) * 1997-10-31 2009-09-24 Metabolix Inc Verwendung von organischen Phosphon- oder Phosphinsäuren, oder von Metall-oxiden oder -hydroxiden, oder von Carbonsäuresalzen eines Metalls als Hitzestabilisatoren für Polyhydroxyalkanoate
JP4069282B2 (ja) * 1998-05-11 2008-04-02 リケンテクノス株式会社 生分解性ポリ乳酸系組成物
CA2341173A1 (en) * 1998-08-21 2000-03-02 Julious L. Wilett Method of making biodegradable polymer compositions
US6174990B1 (en) 1998-12-21 2001-01-16 The Procter & Gamble Company Films comprising biodegradable PHA copolymers
US6160199A (en) * 1998-12-21 2000-12-12 The Procter & Gamble Company Absorbent articles comprising biodegradable PHA copolymers
US6077931A (en) * 1998-12-21 2000-06-20 The Procter & Gamble Company Biodegradable PHA copolymers
US7037959B1 (en) * 1999-04-12 2006-05-02 The United States Of America As Represented By The Secretary Of The Agriculture Biodegradable polymer compositions methods for making same and articles therefrom
WO2000068409A1 (en) * 1999-05-12 2000-11-16 Metabolix, Inc. Methods for purifying polyhydroxyalkanoates
DE60029289T2 (de) 1999-10-05 2007-07-26 Nippon Shokubai Co., Ltd. Biologisch abbaubare Polyesterharzzusammensetzung und ihre Verwendung
US6413017B2 (en) * 2000-03-14 2002-07-02 Jonathan B. Scott Conversion of hydrocarbon-contaminated particulate soil and/or rock to fertile soil useful in erosion control
AU2001276597A1 (en) * 2000-08-11 2002-02-25 Bio-Tec Biologische Naturverpackungen Gmbh And Co.Kg Biodegradable polymeric blend
EP1325079B1 (de) * 2000-10-06 2005-12-21 The Procter & Gamble Company Kunststoffgegenstände aus bioabbaubarem polyester mischzusammensetzungen
US7265188B2 (en) * 2000-10-06 2007-09-04 The Procter & Gamble Company Biodegradable polyester blend compositions and methods of making the same
CA2420430A1 (en) * 2000-10-06 2002-04-11 The Procter & Gamble Company Absorbent articles comprising biodegradable polyester blend compositions
KR100797903B1 (ko) 2000-12-01 2008-01-24 도레이 가부시끼가이샤 폴리에스테르 조성물, 그것으로 이루어지는 필름 및폴리에스테르 조성물의 제조방법
FR2819812B1 (fr) * 2001-01-23 2005-04-01 Atofina Piegeage d'un monomere residuel contenant au moins une fonction epoxyde dans une composition thermoplastique
DE10137046A1 (de) * 2001-07-31 2003-02-20 Basf Ag Verfahren zur Herstellung von thermoplastischen Poly(3-hydroxyalkanoaten)
BR0211556A (pt) * 2001-08-01 2004-07-13 Fuller H B Licensing Financ Composição respirável biodegradável fundida por calor
DE10208810A1 (de) 2002-03-01 2003-09-11 Basf Ag Verfahren zur Herstellung von Poly(3-hydroxyalkanoaten) in Gegenwart eines Nucleophils
AU2004245567B2 (en) 2003-06-03 2011-06-23 Oxford University Innovation Limited Nutritional supplements and therapeutic compositions comprising (R)-3-hydroxybutyrate derivatives
AU2003292860B2 (en) 2003-12-19 2010-03-04 Tianan Biologic Material Co., Ltd. Ningbo A method for Separating, Extracting and Purifying Poly- beta -hydroxyalkanoates (PHA's) directly from Bacterial Fermentation Broth
US7776020B2 (en) * 2004-03-19 2010-08-17 Kimberly-Clark Worldwide, Inc. Absorbent articles having an aliphatic-aromatic copolyester film
US7153569B2 (en) * 2004-03-19 2006-12-26 Kimberly-Clark Worldwide, Inc. Biodegradable aliphatic-aromatic copolyester films
JP4403846B2 (ja) * 2004-03-22 2010-01-27 東レ株式会社 ポリ乳酸のラクチド除去法
JP4403845B2 (ja) * 2004-03-22 2010-01-27 東レ株式会社 ラクチド含有量が少ないポリ乳酸の製造方法
CN100572427C (zh) * 2004-04-26 2009-12-23 富士胶片株式会社 纤维素酰化物薄膜和纤维素酰化物颗粒的制造方法
TW200613560A (en) * 2004-06-29 2006-05-01 Procter & Gamble Solvent extraction of polyhydroxyalkanoates from biomass
US20080207870A1 (en) * 2004-08-31 2008-08-28 Riken Thermostable Biopolyester
US8007775B2 (en) * 2004-12-30 2011-08-30 Advanced Cardiovascular Systems, Inc. Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same
DE102005017049A1 (de) * 2005-04-12 2006-10-19 Basf Ag Verfahren zur Herstellung von Polyhydroxyalkanoaten
CN101370851B (zh) * 2006-01-17 2011-11-16 巴斯夫欧洲公司 制备具有较小碱金属和碱土金属浓度和较大热稳定性的多羟基链烷酸酯的方法
CN101711374B (zh) 2007-03-08 2011-11-02 澳加光学有限公司 乙二醇改性聚酯眼镜和眼镜镜架
WO2008143176A1 (ja) * 2007-05-18 2008-11-27 Toyo Boseki Kabushiki Kaisha 耐熱性の向上したポリ３－ヒドロキシブチレート又はポリ３－ヒドロキシブチレート共重合体およびその製造法
US20090112259A1 (en) * 2007-10-31 2009-04-30 Angiotech Pharmaceuticals, Inc. Recombinant expressed bioadsorbable polyhydroxyalkonate monofilament and multi-filaments self-retaining sutures
EP2240017B1 (de) 2008-01-04 2019-03-13 Oxford University Innovation Limited Ketonkörper und ketonkörperester als blutfettsenkende mittel
US20150135580A1 (en) * 2008-02-28 2015-05-21 College Of William And Mary Fishing gear with degradable component
US8938908B2 (en) * 2008-02-28 2015-01-27 College Of William And Mary Fishing gear with degradable component
US8642654B2 (en) 2009-04-16 2014-02-04 Isis Innovation Limited Hydroxybutyrate ester and medical use thereof
ES2688444T3 (es) 2009-06-26 2018-11-02 Cj Cheiljedang Corporation Método de fabricación de un artículo a partir de una composición que comprende PHA y PBS
US8586821B2 (en) * 2009-12-23 2013-11-19 Kimberly-Clark Worldwide, Inc. Melt-processed films of thermoplastic cellulose and microbial aliphatic polyester
GB201002983D0 (en) 2010-02-22 2010-04-07 Tdeltas Ltd Nutritinal composition
EP2668250B1 (de) 2011-01-25 2019-04-24 Enlighten Innovations Inc. Herstellung von brennstoffen aus aus biomasse gewonnenen chemikalien
US9370482B1 (en) 2011-09-09 2016-06-21 Harrison Yu Method of incorporating additives to shaped porous monocomponent biopolymer fibers during fiber orienting step
US9520074B2 (en) * 2012-02-23 2016-12-13 College Of William And Mary Degradable identification component
US10113060B2 (en) 2012-06-05 2018-10-30 Cj Cheiljedang Corporation Biobased rubber modified biodegradable polymer blends
US9540661B2 (en) 2012-07-09 2017-01-10 Basf Se Method for the complete anaerobic digestion of polymer mixtures
WO2014009176A1 (de) 2012-07-10 2014-01-16 Basf Se Verfahren zum vollständigen anaeroben abbau von polymermischungen
DE102012212437A1 (de) * 2012-07-16 2014-01-16 Basf Se Verfahren zur Herstellung von Acrylsäure aus Ethylenoxid und Kohlenmonoxid
JP6883384B2 (ja) 2012-11-05 2021-06-09 ザ ユナイテッド ステイツ オブ アメリカ， アズ リプレゼンテッド バイ ザ セクレタリー， デパートメント オブ ヘルス アンド ヒューマン サービシーズ 電離放射線による傷害から組織を防護するためのケトン体
GB201304467D0 (en) 2013-03-12 2013-04-24 Tdeltas Ltd Compound for use in protecting skin
SG11201507685UA (en) 2013-03-14 2015-10-29 Isis Innovation Process for producing (r)-3-hydroxybutyl (r)-3-hydroxybutyrate
US9441096B2 (en) 2014-09-26 2016-09-13 Fuji Xerox Co., Ltd. Resin composition and resin shaped product
JP6630998B2 (ja) * 2014-09-26 2020-01-15 富士ゼロックス株式会社 樹脂組成物、及び樹脂成形体
US11091632B2 (en) 2015-11-17 2021-08-17 Cj Cheiljedang Corporation Polymer blends with controllable biodegradation rates
JP6993980B2 (ja) * 2016-10-13 2022-02-04 株式会社カネカ ポリヒドロキシアルカン酸の製造方法
JP2018127579A (ja) * 2017-02-10 2018-08-16 富士ゼロックス株式会社 樹脂組成物および樹脂成形体
US11820881B2 (en) 2020-04-02 2023-11-21 Singular Solutions Inc. Plastic pro-biodegradation additives, biodegradable plastic compositions, and related methods
US12054685B1 (en) 2020-07-15 2024-08-06 National Technology & Engineering Solutions Of Sandia, Llc Coupling high yield biochemical intermediates for fuel production
CA3192757A1 (en) 2020-09-17 2022-03-24 Mirek Planeta Ultra-fast marine-biodegradable composite film
JP2024517602A (ja) 2021-04-16 2024-04-23 ノボマー， インコーポレイテッド ポリプロピオラクトン及びその調製方法
WO2024101851A1 (en) * 2022-11-07 2024-05-16 Cj Cheiljedang Corporation Compositions comprising amorphous polyhydroxyalkanoate and use thereof
CN121443671A (zh) * 2023-07-07 2026-01-30 国立大学法人筑波大学 包含聚([R,S]β-羟基丁酸)重复单元的嵌段共聚物和来自该共聚物的纳米颗粒、以及它们的制备和用途

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA742294A (en) * 1966-09-06 H. Mullins Dennis Plasticization of vinyl resins with lactone polyesters
US2917410A (en) * 1955-06-20 1959-12-15 American Cyanamid Co Polyglycol-polyacid ester treatment of textiles
US3021309A (en) * 1959-12-03 1962-02-13 Union Carbide Corp Polymerization of cyclic esters
US3021312A (en) * 1959-12-03 1962-02-13 Union Carbide Corp Polymerization of cyclic esters
US3021310A (en) * 1959-12-03 1962-02-13 Union Garbide Corp Polymerization of cyclic esters
US3021311A (en) * 1959-12-03 1962-02-13 Union Carbide Corp Polymerization of cyclic esters
US3021314A (en) * 1959-12-03 1962-02-13 Union Carbide Corp Polymerization of cyclic esters
US3021317A (en) * 1959-12-03 1962-02-13 Union Carbide Corp Polymerization of cyclic esters
US3021316A (en) * 1959-12-03 1962-02-13 Union Carbide Corp Polymerization of cyclic esters
US3021313A (en) * 1959-12-03 1962-02-13 Union Carbide Corp Polymerization of cyclic esters
US3021315A (en) * 1959-12-03 1962-02-13 Union Carbide Corp Polymerization of cyclic esters
US3522219A (en) * 1966-01-21 1970-07-28 Montedison Spa Process for the suspension polymerization of beta-substituted-beta-lactones
NL161475C (nl) * 1970-01-29 1980-02-15 Stamicarbon Bereiding van lactonpolyesters.
US3922239A (en) * 1971-05-06 1975-11-25 Union Carbide Corp Cellulose esters or ethers blended with cyclic ester polymers
US3781381A (en) * 1971-05-06 1973-12-25 Union Carbide Corp Nylon polymers blended with cyclic ester polymers
EP0078609B1 (de) * 1980-04-30 1987-05-06 Imperial Chemical Industries Plc 3-Hydroxybuttersäure-Polymere
US4372311A (en) * 1980-09-12 1983-02-08 Union Carbide Corporation Disposable articles coated with degradable water insoluble polymers
EP0052460B1 (de) * 1980-11-18 1985-02-06 Imperial Chemical Industries Plc Polymerzusammensetzungen
US4349469A (en) * 1981-02-17 1982-09-14 Eastman Kodak Company Copolyesterethers
JPH0660236B2 (ja) * 1984-05-30 1994-08-10 ダイセル化学工業株式会社 新規なラクトン重合体の製造方法
US4699974A (en) * 1986-08-07 1987-10-13 General Electric Company Method of preparing copolyester carbonate from cyclic aromatic polycarbonate oligomer and lactone
AU603076B2 (en) * 1985-12-09 1990-11-08 W.R. Grace & Co.-Conn. Polymeric products and their manufacture
US5023316A (en) * 1990-06-14 1991-06-11 Exxon Chemical Patents, Inc. Catalytic polymerization of β-substituted-β-propiolactones by oligomeric isobutylaluminoxane
JPH0465425A (ja) * 1990-07-06 1992-03-02 Showa Denko Kk 共重合体及びその製造法
US5076983A (en) * 1990-07-16 1991-12-31 E. I. Du Pont De Nemours And Company Polyhydroxy acid films
GB9016345D0 (en) * 1990-07-25 1990-09-12 Ici Plc Polymer blends
CA2090977A1 (en) * 1990-09-11 1992-03-12 George J. Ostapchenko Films containing polyhydroxy acids

Also Published As

Publication number Publication date
EP0909789A3 (de) 1999-06-09
DE69326341T2 (de) 2000-02-03
EP0909789B1 (de) 2003-09-24
DK0648238T3 (da) 1999-12-20
EP0648238A1 (de) 1995-04-19
ES2135482T3 (es) 1999-11-01
ATE250645T1 (de) 2003-10-15
EP0648238B1 (de) 1999-09-08
DE69326341D1 (de) 1999-10-14
US5391708A (en) 1995-02-21
MX9303692A (es) 1994-01-31
EP0909789A2 (de) 1999-04-21
JPH08500131A (ja) 1996-01-09
DE69333220T2 (de) 2004-04-08
US5552515A (en) 1996-09-03
CA2138034C (en) 1999-03-02
CA2138034A1 (en) 1994-01-06
DE69333220D1 (de) 2003-10-30
KR950702221A (ko) 1995-06-19
GR3031600T3 (en) 2000-01-31
WO1994000506A1 (en) 1994-01-06
US5625029A (en) 1997-04-29
US5281691A (en) 1994-01-25

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