ATE185143T1 - Glatten-muskelzellen-proliferation-inhibitoren - Google Patents

Glatten-muskelzellen-proliferation-inhibitoren

Info

Publication number: ATE185143T1
Authority: AT; Austria
Prior art keywords: smooth muscle; muscle cell; cell proliferation; carbon atoms; image
Prior art date: 1994-11-07

Application number

AT95939137T

Other languages

English (en)

Inventor

Sarah Tobin Allen Novak

Richard Michael Soll

Original Assignee

American Home Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-07

Filing date

1995-11-03

Publication date

1999-10-15

1995-11-03 Application filed by American Home Prod filed Critical American Home Prod

1999-10-15 Application granted granted Critical

1999-10-15 Publication of ATE185143T1 publication Critical patent/ATE185143T1/de

Links

239000003112 inhibitor Substances 0.000 title abstract 2
210000000329 smooth muscle myocyte Anatomy 0.000 title abstract 2
230000004663 cell proliferation Effects 0.000 title 1
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 2
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical group [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical group [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
230000001028 anti-proliverative effect Effects 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229910052744 lithium Inorganic materials 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000002482 oligosaccharides Polymers 0.000 abstract 1
229910052700 potassium Inorganic materials 0.000 abstract 1
239000011591 potassium Chemical group 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000002460 smooth muscle Anatomy 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
239000011734 sodium Chemical group 0.000 abstract 1
125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Hydrogenated Pyridines (AREA)
Saccharide Compounds (AREA)

AT95939137T 1994-11-07 1995-11-03 Glatten-muskelzellen-proliferation-inhibitoren ATE185143T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US08/335,010 US5565432A (en)	1994-11-07	1994-11-07	Smooth muscle cell proliferation inhibitors

Publications (1)

Publication Number	Publication Date
ATE185143T1 true ATE185143T1 (de)	1999-10-15

Family

ID=23309857

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95939137T ATE185143T1 (de)	1994-11-07	1995-11-03	Glatten-muskelzellen-proliferation-inhibitoren

Country Status (19)

Country	Link
US (1)	US5565432A (de)
EP (1)	EP0791005B1 (de)
JP (1)	JPH10508607A (de)
KR (1)	KR970707140A (de)
AT (1)	ATE185143T1 (de)
AU (1)	AU699670B2 (de)
BR (1)	BR9509608A (de)
DE (1)	DE69512528T2 (de)
DK (1)	DK0791005T3 (de)
ES (1)	ES2136888T3 (de)
FI (1)	FI971936A7 (de)
GR (1)	GR3031682T3 (de)
HU (2)	HUT77005A (de)
IL (1)	IL115747A (de)
MX (1)	MX9703286A (de)
NZ (1)	NZ296459A (de)
TW (1)	TW403758B (de)
WO (1)	WO1996014324A1 (de)
ZA (1)	ZA959436B (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2174582A1 (en) *	1995-05-05	1996-11-06	Alexander Chucholowski	Sulphuric acid esters of amino-sugars
WO1997045105A1 (en)	1996-05-24	1997-12-04	Angiotech Pharmaceuticals, Inc.	Compositions and methods for treating or preventing diseases of body passageways
US6664243B1 (en)	1998-11-24	2003-12-16	Wyeth	Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US7081448B2 (en)	1998-11-24	2006-07-25	Wyeth	Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) *	1998-11-24	2006-11-07	Wyeth	Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6451767B1 (en)	1998-11-24	2002-09-17	Wyeth	Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en)	1998-11-24	2002-01-15	American Home Products Corporation	Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en)	1998-11-24	2001-09-18	American Home Products Corp.	Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en)	1998-11-24	2002-03-26	American Home Products Corporation	Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
BR9915632A (pt) *	1998-11-24	2001-08-07	American Home Prod	Benzilmaltosìdeos acilados como inibidores da proliferação de células musculares lisas
US6258784B1 (en)	1998-11-24	2001-07-10	American Home Products Corp.	Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en)	1998-11-24	2002-01-22	American Home Products Corporation	Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6187755B1 (en)	1998-11-24	2001-02-13	American Home Products Corporation	Benzylmaltosides as inhibitors of smooth muscle cell proliferation
ATE299491T1 (de)	2000-09-07	2005-07-15	Telik Inc	Benzoltricarbonsäureamide als aktivatoren des insulinrezeptors

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4562485A (en) *	1979-08-10	1985-12-31	Canon Kabushiki Kaisha	Copying apparatus
US4431636A (en) *	1982-05-24	1984-02-14	American Cyanamid Company	Bis(4-O-polyhexaose-thio)-phenyl ureas and method of use
US4435387A (en) *	1982-10-25	1984-03-06	American Cyanamid Company	Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
US4440758A (en) *	1982-10-25	1984-04-03	American Cyanamid Company	Poly-cation salts of bis(or tris)[4-O-monohexose-oxy]-arylene sulfate derivatives
US4431638A (en) *	1982-10-25	1984-02-14	American Cyanamid Company	Poly-cation salts of bis(or tris)[4-0-monohexose-thio]-arylene sulfate derivatives
US4431637A (en) *	1982-10-25	1984-02-14	American Cyanamid Company	Polycation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives
US4870500A (en) *	1985-09-30	1989-09-26	Canon Kabushiki Kaisha	Image signal processing apparatus
US4788599A (en) *	1986-04-01	1988-11-29	Canon Kabushiki Kaisha	Image processing with image-slant control and/or image-size control
US5029017A (en) *	1986-10-08	1991-07-02	Konishiroku Photo Industry Co., Ltd.	Image processing apparatus capable of enlarging/reducing apparatus
DE3734815A1 (de) *	1987-10-14	1989-04-27	Luitpold Werk Chem Pharm	Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel
DE3734853A1 (de) *	1987-10-14	1989-04-27	Luitpold Werk Chem Pharm	Bis-aldonsaeureamide und verfahren zu ihrer herstellung
US5019562A (en) *	1988-01-19	1991-05-28	The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation	Growth inhibiting agent and the use thereof
FR2634485B1 (fr) *	1988-07-21	1992-02-28	Sanopi	Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant
JPH02161872A (ja) *	1988-12-14	1990-06-21	Fuji Xerox Co Ltd	画像処理装置の縮拡処理方式
US5032679A (en) *	1988-12-15	1991-07-16	Glycomed, Inc.	Heparin fragments as inhibitors of smooth muscle cell proliferation
EP0454220B1 (de) *	1990-04-23	1993-08-18	Akzo Nobel N.V.	Eine Trisaccharideinheit enthaltende Kohlenhydratderivate
BR9206736A (pt) *	1991-11-11	1995-10-31	Univ Pennsylvania	Composição para afetar o crescimento de tecido vivo em mamíferos processos para promover a angiogenese em mamíferos para tratar tecido transplantado ou órgãos em mamíferos e para tratar osso danificado ou transplantado

1994
- 1994-11-07 US US08/335,010 patent/US5565432A/en not_active Expired - Lifetime
1995
- 1995-10-24 IL IL11574795A patent/IL115747A/xx not_active IP Right Cessation
- 1995-11-03 ES ES95939137T patent/ES2136888T3/es not_active Expired - Lifetime
- 1995-11-03 WO PCT/US1995/014737 patent/WO1996014324A1/en not_active Ceased
- 1995-11-03 EP EP95939137A patent/EP0791005B1/de not_active Expired - Lifetime
- 1995-11-03 FI FI971936A patent/FI971936A7/fi unknown
- 1995-11-03 KR KR1019970703022A patent/KR970707140A/ko not_active Withdrawn
- 1995-11-03 HU HU9702077A patent/HUT77005A/hu unknown
- 1995-11-03 HU HU9800942A patent/HUT77756A/hu unknown
- 1995-11-03 MX MX9703286A patent/MX9703286A/es unknown
- 1995-11-03 AT AT95939137T patent/ATE185143T1/de not_active IP Right Cessation
- 1995-11-03 JP JP8515532A patent/JPH10508607A/ja active Pending
- 1995-11-03 DK DK95939137T patent/DK0791005T3/da active
- 1995-11-03 NZ NZ296459A patent/NZ296459A/xx unknown
- 1995-11-03 DE DE69512528T patent/DE69512528T2/de not_active Expired - Fee Related
- 1995-11-03 BR BR9509608A patent/BR9509608A/pt not_active IP Right Cessation
- 1995-11-03 AU AU41081/96A patent/AU699670B2/en not_active Ceased
- 1995-11-07 ZA ZA9509436A patent/ZA959436B/xx unknown
- 1995-11-16 TW TW084112132A patent/TW403758B/zh active
1999
- 1999-10-27 GR GR990402772T patent/GR3031682T3/el unknown

Also Published As

Publication number	Publication date
AU699670B2 (en)	1998-12-10
IL115747A (en)	1999-12-31
KR970707140A (ko)	1997-12-01
US5565432A (en)	1996-10-15
FI971936L (fi)	1997-05-06
HUT77005A (hu)	1998-03-02
WO1996014324A1 (en)	1996-05-17
FI971936A0 (fi)	1997-05-06
GR3031682T3 (en)	2000-02-29
DK0791005T3 (da)	2000-03-27
DE69512528T2 (de)	2000-05-31
MX9703286A (es)	1997-08-30
ZA959436B (en)	1997-08-07
EP0791005B1 (de)	1999-09-29
BR9509608A (pt)	1997-10-28
TW403758B (en)	2000-09-01
DE69512528D1 (de)	1999-11-04
EP0791005A1 (de)	1997-08-27
IL115747A0 (en)	1996-01-19
ES2136888T3 (es)	1999-12-01
NZ296459A (en)	1999-01-28
AU4108196A (en)	1996-05-31
HUT77756A (hu)	1998-07-28
JPH10508607A (ja)	1998-08-25
FI971936A7 (fi)	1997-05-06

Legal Events

Date	Code	Title	Description
2000-02-15	UEP	Publication of translation of european patent specification
2001-08-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DK0791006T3 (da)	2000-04-17	Polyanioniske benzylglylcosider som inhibitorer af proliferation af glatte muskelceller
LU91587I2 (fr)	2009-09-22	Agomélatine et ses dérivés pharmaceutiquement acceptables (VALDOXAN)
ATE185143T1 (de)	1999-10-15	Glatten-muskelzellen-proliferation-inhibitoren
FI810389L (fi)	1981-08-14	Foerfarande foer framstaellning av substituerade imidazolderivat
DE60107435D1 (de)	2004-12-30	2-adamantylethylamine und deren verwendung bei der behandlung von abnormalitäten in der glutamat transmission
ES2124545T3 (es)	1999-02-01	Azolidindionas como agentes antihiperglucemicos.
CS327391A3 (en)	1992-05-13	Novel 3-cycloalkylpropaneamides, their tautomeric forms and their salts, process of their preparation and their application as medicaments and compositions containing said 3-cycloalkylpropaneamides
NZ296037A (en)	1999-05-28	Acylated benzylglycoside derivatives, preparation and pharmaceutical compositions thereof
SE8406302L (sv)	1985-06-13	Nya aminoguanidinderivat och ett forfarande for deras framstellning
ATE238300T1 (de)	2003-05-15	(3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine
ATE97128T1 (de)	1993-11-15	Sparsomycinderivate.