DK0791005T3 - Inhibitorer af proliferation af glatte muskelceller - Google Patents

Inhibitorer af proliferation af glatte muskelceller

Info

Publication number: DK0791005T3
Authority: DK; Denmark
Prior art keywords: smooth muscle; inhibitors; muscle cell; cell proliferation; carbon atoms
Prior art date: 1994-11-07

Application number

DK95939137T

Other languages

English (en)

Inventor

Richard Michael Soll

Sarah Tobin Allen Novak

Original Assignee

American Home Prod

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-11-07

Filing date

1995-11-03

Publication date

2000-03-27

1995-11-03 Application filed by American Home Prod filed Critical American Home Prod

2000-03-27 Application granted granted Critical

2000-03-27 Publication of DK0791005T3 publication Critical patent/DK0791005T3/da

Links

239000003112 inhibitor Substances 0.000 title abstract 2
210000000329 smooth muscle myocyte Anatomy 0.000 title abstract 2
230000004663 cell proliferation Effects 0.000 title 1
UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
125000004432 carbon atom Chemical group C* 0.000 abstract 2
QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical group C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
WHXSMMKQMYFTQS-UHFFFAOYSA-N Lithium Chemical group [Li] WHXSMMKQMYFTQS-UHFFFAOYSA-N 0.000 abstract 1
ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical group [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000000217 alkyl group Chemical group 0.000 abstract 1
150000001408 amides Chemical class 0.000 abstract 1
230000001028 anti-proliverative effect Effects 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
229910052744 lithium Inorganic materials 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
150000002482 oligosaccharides Polymers 0.000 abstract 1
229910052700 potassium Inorganic materials 0.000 abstract 1
239000011591 potassium Chemical group 0.000 abstract 1
230000035755 proliferation Effects 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
210000002460 smooth muscle Anatomy 0.000 abstract 1
229910052708 sodium Inorganic materials 0.000 abstract 1
239000011734 sodium Chemical group 0.000 abstract 1
125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

DK95939137T 1994-11-07 1995-11-03 Inhibitorer af proliferation af glatte muskelceller DK0791005T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US08/335,010 US5565432A (en)	1994-11-07	1994-11-07	Smooth muscle cell proliferation inhibitors
PCT/US1995/014737 WO1996014324A1 (en)	1994-11-07	1995-11-03	Smooth muscle cell proliferation inhibitors

Publications (1)

Publication Number	Publication Date
DK0791005T3 true DK0791005T3 (da)	2000-03-27

Family

ID=23309857

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95939137T DK0791005T3 (da)	1994-11-07	1995-11-03	Inhibitorer af proliferation af glatte muskelceller

Country Status (19)

Country	Link
US (1)	US5565432A (da)
EP (1)	EP0791005B1 (da)
JP (1)	JPH10508607A (da)
KR (1)	KR970707140A (da)
AT (1)	ATE185143T1 (da)
AU (1)	AU699670B2 (da)
BR (1)	BR9509608A (da)
DE (1)	DE69512528T2 (da)
DK (1)	DK0791005T3 (da)
ES (1)	ES2136888T3 (da)
FI (1)	FI971936A0 (da)
GR (1)	GR3031682T3 (da)
HU (2)	HUT77756A (da)
IL (1)	IL115747A (da)
MX (1)	MX9703286A (da)
NZ (1)	NZ296459A (da)
TW (1)	TW403758B (da)
WO (1)	WO1996014324A1 (da)
ZA (1)	ZA959436B (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2174582A1 (en) *	1995-05-05	1996-11-06	Alexander Chucholowski	Sulphuric acid esters of amino-sugars
ES2248847T3 (es)	1996-05-24	2006-03-16	Angiotech Pharmaceuticals, Inc.	Composiciones y metodos para tratar o prevenir enfermedades de las vias de conduccion del cuerpo.
US7081448B2 (en)	1998-11-24	2006-07-25	Wyeth	Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
JP2003521460A (ja) *	1998-11-24	2003-07-15	ワイス	平滑筋細胞増殖の阻害薬としてのアセチル化ベンジルマルトシド
US6340670B1 (en)	1998-11-24	2002-01-22	American Home Products Corporation	Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en)	1998-11-24	2003-12-16	Wyeth	Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en)	1998-11-24	2006-11-07	Wyeth	Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en)	1998-11-24	2001-09-18	American Home Products Corp.	Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en)	1998-11-24	2002-01-15	American Home Products Corporation	Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6451767B1 (en)	1998-11-24	2002-09-17	Wyeth	Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6258784B1 (en)	1998-11-24	2001-07-10	American Home Products Corp.	Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en)	1998-11-24	2002-03-26	American Home Products Corporation	Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6187755B1 (en)	1998-11-24	2001-02-13	American Home Products Corporation	Benzylmaltosides as inhibitors of smooth muscle cell proliferation
AU8889101A (en)	2000-09-07	2002-03-22	Telik Inc	Benzene tricarboxylic acid derivatives as insulin receptor activators

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4562485A (en) *	1979-08-10	1985-12-31	Canon Kabushiki Kaisha	Copying apparatus
US4431636A (en) *	1982-05-24	1984-02-14	American Cyanamid Company	Bis(4-O-polyhexaose-thio)-phenyl ureas and method of use
US4431637A (en) *	1982-10-25	1984-02-14	American Cyanamid Company	Polycation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives
US4440758A (en) *	1982-10-25	1984-04-03	American Cyanamid Company	Poly-cation salts of bis(or tris)[4-O-monohexose-oxy]-arylene sulfate derivatives
US4431638A (en) *	1982-10-25	1984-02-14	American Cyanamid Company	Poly-cation salts of bis(or tris)[4-0-monohexose-thio]-arylene sulfate derivatives
US4435387A (en) *	1982-10-25	1984-03-06	American Cyanamid Company	Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
US4870500A (en) *	1985-09-30	1989-09-26	Canon Kabushiki Kaisha	Image signal processing apparatus
US4788599A (en) *	1986-04-01	1988-11-29	Canon Kabushiki Kaisha	Image processing with image-slant control and/or image-size control
US5029017A (en) *	1986-10-08	1991-07-02	Konishiroku Photo Industry Co., Ltd.	Image processing apparatus capable of enlarging/reducing apparatus
DE3734815A1 (de) *	1987-10-14	1989-04-27	Luitpold Werk Chem Pharm	Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel
DE3734853A1 (de) *	1987-10-14	1989-04-27	Luitpold Werk Chem Pharm	Bis-aldonsaeureamide und verfahren zu ihrer herstellung
US5019562A (en) *	1988-01-19	1991-05-28	The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation	Growth inhibiting agent and the use thereof
FR2634485B1 (fr) *	1988-07-21	1992-02-28	Sanopi	Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant
JPH02161872A (ja) *	1988-12-14	1990-06-21	Fuji Xerox Co Ltd	画像処理装置の縮拡処理方式
US5032679A (en) *	1988-12-15	1991-07-16	Glycomed, Inc.	Heparin fragments as inhibitors of smooth muscle cell proliferation
DK0454220T3 (da) *	1990-04-23	1993-11-22	Sanofi Elf	Carbohydratderivater omfattende en trisaccharidenhed
AU678760B2 (en) *	1991-11-11	1997-06-12	Trustees Of The University Of Pennsylvania, The	Methods of inhibiting restenosis

1994
- 1994-11-07 US US08/335,010 patent/US5565432A/en not_active Expired - Lifetime
1995
- 1995-10-24 IL IL11574795A patent/IL115747A/xx not_active IP Right Cessation
- 1995-11-03 DE DE69512528T patent/DE69512528T2/de not_active Expired - Fee Related
- 1995-11-03 ES ES95939137T patent/ES2136888T3/es not_active Expired - Lifetime
- 1995-11-03 HU HU9800942A patent/HUT77756A/hu unknown
- 1995-11-03 WO PCT/US1995/014737 patent/WO1996014324A1/en not_active Ceased
- 1995-11-03 AT AT95939137T patent/ATE185143T1/de not_active IP Right Cessation
- 1995-11-03 EP EP95939137A patent/EP0791005B1/en not_active Expired - Lifetime
- 1995-11-03 FI FI971936A patent/FI971936A0/fi unknown
- 1995-11-03 AU AU41081/96A patent/AU699670B2/en not_active Ceased
- 1995-11-03 HU HU9702077A patent/HUT77005A/hu unknown
- 1995-11-03 JP JP8515532A patent/JPH10508607A/ja active Pending
- 1995-11-03 DK DK95939137T patent/DK0791005T3/da active
- 1995-11-03 MX MX9703286A patent/MX9703286A/es unknown
- 1995-11-03 NZ NZ296459A patent/NZ296459A/xx unknown
- 1995-11-03 BR BR9509608A patent/BR9509608A/pt not_active IP Right Cessation
- 1995-11-03 KR KR1019970703022A patent/KR970707140A/ko not_active Withdrawn
- 1995-11-07 ZA ZA9509436A patent/ZA959436B/xx unknown
- 1995-11-16 TW TW084112132A patent/TW403758B/zh active
1999
- 1999-10-27 GR GR990402772T patent/GR3031682T3/el unknown

Also Published As

Publication number	Publication date
EP0791005A1 (en)	1997-08-27
JPH10508607A (ja)	1998-08-25
FI971936A7 (fi)	1997-05-06
IL115747A (en)	1999-12-31
EP0791005B1 (en)	1999-09-29
AU699670B2 (en)	1998-12-10
DE69512528T2 (de)	2000-05-31
IL115747A0 (en)	1996-01-19
US5565432A (en)	1996-10-15
NZ296459A (en)	1999-01-28
GR3031682T3 (en)	2000-02-29
HUT77005A (hu)	1998-03-02
DE69512528D1 (de)	1999-11-04
ES2136888T3 (es)	1999-12-01
HUT77756A (hu)	1998-07-28
ATE185143T1 (de)	1999-10-15
ZA959436B (en)	1997-08-07
WO1996014324A1 (en)	1996-05-17
TW403758B (en)	2000-09-01
KR970707140A (ko)	1997-12-01
MX9703286A (es)	1997-08-30
AU4108196A (en)	1996-05-31
FI971936L (fi)	1997-05-06
BR9509608A (pt)	1997-10-28
FI971936A0 (fi)	1997-05-06

Publication	Publication Date	Title
DK0791006T3 (da)	2000-04-17	Polyanioniske benzylglylcosider som inhibitorer af proliferation af glatte muskelceller
LU91587I2 (fr)	2009-09-22	Agomélatine et ses dérivés pharmaceutiquement acceptables (VALDOXAN)
ATE185143T1 (de)	1999-10-15	Glatten-muskelzellen-proliferation-inhibitoren
PT870768E (pt)	2002-09-30	Derivados azaindole-etilamina como agentes de ligacao nicotinicos aos receptores de acetilcolina
DE60107435D1 (de)	2004-12-30	2-adamantylethylamine und deren verwendung bei der behandlung von abnormalitäten in der glutamat transmission
FI810389L (fi)	1981-08-14	Foerfarande foer framstaellning av substituerade imidazolderivat
DK44682A (da)	1982-08-06	Fremgangsmaade til fremstilling af substituerede imidazolderivater
AU8686991A (en)	1992-05-07	New 3-cycloalkyl-propanamides, their tautomer forms and their salts, preparation process, use as medicaments and compositions containing them
DK0791004T3 (da)	1999-11-29	Acylerede benzylglykosider som inhibitorer af glat-muskelceller-proliferation
ES8307760A1 (es)	1983-08-01	Un procedimiento para la preparacion de derivados de 4-anilino-pirimidina.
NO995935D0 (no)	1999-12-03	17<beta>-allyloksy(tio)alkyl-androstan-derivater for modulering av meiose
ES8501416A1 (es)	1984-11-16	5'-alquil o alquenil-fosfatos de nucleosidos.
ATE238300T1 (de)	2003-05-15	(3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl)-3-(1 - indol-3-yl)-alkylamine
ATE97128T1 (de)	1993-11-15	Sparsomycinderivate.
MX9601953A (es)	1997-08-30	Nuevo compesto derivados de 5h-tiazolo [3,2-a] pirimidin-5-ona.