ATE202282T1 - Verwendung von glycosaminoglycanen zur herstellung eines arzneimittels zur behandlung des chronischen nierenversagens - Google Patents

Verwendung von glycosaminoglycanen zur herstellung eines arzneimittels zur behandlung des chronischen nierenversagens

Info

Publication number: ATE202282T1
Authority: AT; Austria
Prior art keywords: peritoneal; glycosaminoglycans; treatment; sulodexide; subjected
Prior art date: 1994-10-06

Application number

AT95113868T

Other languages

English (en)

Inventor

Bruno Baggio

Giorgio Bazzato

Agostino Fracasso

Giovanni Gambaro

Egidio Marchi

Gianfranco Tamagnone

Original Assignee

Alfa Wassermann Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-06

Filing date

1995-09-04

Publication date

2001-07-15

1995-09-04 Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa

2001-07-15 Application granted granted Critical

2001-07-15 Publication of ATE202282T1 publication Critical patent/ATE202282T1/de

Links

208000020832 chronic kidney disease Diseases 0.000 title abstract 3
229920002683 Glycosaminoglycan Polymers 0.000 title abstract 2
208000022831 chronic renal failure syndrome Diseases 0.000 title 1
229940126601 medicinal product Drugs 0.000 title 1
GRYSXUXXBDSYRT-WOUKDFQISA-N (2r,3r,4r,5r)-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol Chemical compound C1=NC=2C(NC)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1OC GRYSXUXXBDSYRT-WOUKDFQISA-N 0.000 abstract 2
229920000439 Sulodexide Polymers 0.000 abstract 2
DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 abstract 2
238000007912 intraperitoneal administration Methods 0.000 abstract 2
229960003491 sulodexide Drugs 0.000 abstract 2
229920000045 Dermatan sulfate Polymers 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
241000700159 Rattus Species 0.000 abstract 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
239000004202 carbamide Substances 0.000 abstract 1
229940109239 creatinine Drugs 0.000 abstract 1
AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 abstract 1
229940051593 dermatan sulfate Drugs 0.000 abstract 1
238000000502 dialysis Methods 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000003055 low molecular weight heparin Substances 0.000 abstract 1
229940127215 low-molecular weight heparin Drugs 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
230000032258 transport Effects 0.000 abstract 1
238000000108 ultra-filtration Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Cell Biology (AREA)
Engineering & Computer Science (AREA)
Developmental Biology & Embryology (AREA)
Immunology (AREA)
Biotechnology (AREA)
Virology (AREA)
Physiology (AREA)
Biomedical Technology (AREA)
Nutrition Science (AREA)
Zoology (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
External Artificial Organs (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT95113868T 1994-10-06 1995-09-04 Verwendung von glycosaminoglycanen zur herstellung eines arzneimittels zur behandlung des chronischen nierenversagens ATE202282T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITBO940436A IT1274351B (it)	1994-10-06	1994-10-06	Uso di alcuni glicosaminoglicani nella dialisi peritoneale.

Publications (1)

Publication Number	Publication Date
ATE202282T1 true ATE202282T1 (de)	2001-07-15

Family

ID=11340040

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT95113868T ATE202282T1 (de)	1994-10-06	1995-09-04	Verwendung von glycosaminoglycanen zur herstellung eines arzneimittels zur behandlung des chronischen nierenversagens

Country Status (9)

Country	Link
US (1)	US5686432A (de)
EP (1)	EP0710483B1 (de)
AT (1)	ATE202282T1 (de)
DE (1)	DE69521388T2 (de)
DK (1)	DK0710483T3 (de)
ES (1)	ES2157277T3 (de)
GR (1)	GR3036158T3 (de)
IT (1)	IT1274351B (de)
PT (1)	PT710483E (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL127896A0 (en) *	1998-12-31	1999-10-28	Gail Laster	A novel treatment for preeclampsia and related diseases
JP2003504428A (ja) *	1999-06-30	2003-02-04	ハミルトンシビックホスピタルズリサーチディベロップメントインコーポレイテッド	クロット関連凝固因子を阻害するヘパリン組成物
ITMI991503A1 (it) *	1999-07-08	2001-01-08	Bidifarm S R L	Uso di metaboliti oligosaccaridici di proteoglicani come maker in fluidi biologici di diagnosi del biabete e delle complicanze patologiche c
US7259152B2 (en) *	2000-06-07	2007-08-21	Alfa Wasserman, Inc.	Methods and compositions using sulodexide for the treatment of diabetic nephropathy
AU2001291549A1 (en) *	2000-09-08	2002-03-22	Hamilton Civic Hospitals Research Development Inc.	Antithrombotic compositions
US20030008844A1 (en) *	2001-05-17	2003-01-09	Keryx Biopharmaceuticals, Inc.	Use of sulodexide for the treatment of inflammatory bowel disease
US20030013680A1 (en) *	2001-06-12	2003-01-16	Keryx	Methods using glycosaminoglycans for the treatment of nephropathy
PE20030263A1 (es) *	2001-07-31	2003-04-17	Novartis Ag	Composicion farmaceutica oftalmica
EP1890686B1 (de)	2005-05-30	2017-10-04	Fresenius Medical Care Deutschland GmbH	Peritonealdialyseflüssigkeit
MX2008008213A (es)	2005-12-22	2008-09-03	Neurochem Int Ltd	Tratamiento de trastornos renales, nefropatia diabetica y dislipidemias.
US20070155672A1 (en) *	2006-01-05	2007-07-05	Markus Voges	Sterilized peritoneal dialysis solutions containing heparin
WO2009044765A1 (ja) *	2007-10-01	2009-04-09	Seikagaku Corporation	新規な低分子化コンドロイチン硫酸およびその用途
CN101632686A (zh) *	2008-04-04	2010-01-27	马斯特里赫特大学	糖胺聚糖用于修复糖萼的用途
IT1401253B1 (it)	2010-04-23	2013-07-18	Uni Degli Studi Carlo Bo Urbino	Uso del sulodexide per la riduzione delle metalloproteinasi di matrice.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1245907B (it) *	1991-05-17	1994-10-25	Alfa Wassermann Spa	Uso dei glicosaminoglicani nel trattamento della nefropatia diabetica e della neuropatia diabetica.
IT1270846B (it) *	1993-05-10	1997-05-13	Alfa Wassermann Spa	Uso di sulodexide e delle specialita' medicinali che lo contengono nel trattamento della nefropatia diabetica.
DE69429576T2 (de) *	1993-09-30	2002-08-22	Seikagaku Kogyo K.K., Tokio/Tokyo	Dermatansulfatezusammensetzung als antithromotisches mittel

1994
- 1994-10-06 IT ITBO940436A patent/IT1274351B/it active IP Right Grant
1995
- 1995-09-04 DK DK95113868T patent/DK0710483T3/da active
- 1995-09-04 AT AT95113868T patent/ATE202282T1/de active
- 1995-09-04 PT PT95113868T patent/PT710483E/pt unknown
- 1995-09-04 EP EP95113868A patent/EP0710483B1/de not_active Expired - Lifetime
- 1995-09-04 ES ES95113868T patent/ES2157277T3/es not_active Expired - Lifetime
- 1995-09-04 DE DE69521388T patent/DE69521388T2/de not_active Expired - Lifetime
- 1995-09-19 US US08/530,597 patent/US5686432A/en not_active Expired - Lifetime
2001
- 2001-06-29 GR GR20010401009T patent/GR3036158T3/el unknown

Also Published As

Publication number	Publication date
PT710483E (pt)	2001-09-28
ITBO940436A1 (it)	1996-04-06
ITBO940436A0 (it)	1994-10-06
EP0710483B1 (de)	2001-06-20
US5686432A (en)	1997-11-11
DK0710483T3 (da)	2001-09-03
IT1274351B (it)	1997-07-17
DE69521388D1 (de)	2001-07-26
DE69521388T2 (de)	2001-10-11
EP0710483A1 (de)	1996-05-08
ES2157277T3 (es)	2001-08-16
GR3036158T3 (en)	2001-09-28

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