GR3036158T3 - Use of some glycosaminoglycans for the manufacture of a medicament for the treatment of chronic renal failure - Google Patents

Use of some glycosaminoglycans for the manufacture of a medicament for the treatment of chronic renal failure

Info

Publication number: GR3036158T3
Authority: GR; Greece
Prior art keywords: peritoneal; chronic renal; glycosaminoglycans; treatment; sulodexide
Prior art date: 1994-10-06

Application number

GR20010401009T

Other languages

English (en)

Inventor

Bruno Baggio

Giorgio Bazzato

Agostino Fracasso

Giovanni Gambaro

Egidio Marchi

Gianfranco Tamagnone

Original Assignee

Alfa Wassermann Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-06

Filing date

2001-06-29

Publication date

2001-09-28

2001-06-29 Application filed by Alfa Wassermann Spa filed Critical Alfa Wassermann Spa

2001-09-28 Publication of GR3036158T3 publication Critical patent/GR3036158T3/el

Links

208000020832 chronic kidney disease Diseases 0.000 title abstract 3
229920002683 Glycosaminoglycan Polymers 0.000 title abstract 2
239000003814 drug Substances 0.000 title abstract 2
208000022831 chronic renal failure syndrome Diseases 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
GRYSXUXXBDSYRT-WOUKDFQISA-N (2r,3r,4r,5r)-2-(hydroxymethyl)-4-methoxy-5-[6-(methylamino)purin-9-yl]oxolan-3-ol Chemical compound C1=NC=2C(NC)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1OC GRYSXUXXBDSYRT-WOUKDFQISA-N 0.000 abstract 2
229920000439 Sulodexide Polymers 0.000 abstract 2
DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 abstract 2
238000007912 intraperitoneal administration Methods 0.000 abstract 2
229960003491 sulodexide Drugs 0.000 abstract 2
229920000045 Dermatan sulfate Polymers 0.000 abstract 1
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 abstract 1
241000700159 Rattus Species 0.000 abstract 1
XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 abstract 1
239000004202 carbamide Substances 0.000 abstract 1
229940109239 creatinine Drugs 0.000 abstract 1
AVJBPWGFOQAPRH-FWMKGIEWSA-L dermatan sulfate Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@H](OS([O-])(=O)=O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](C([O-])=O)O1 AVJBPWGFOQAPRH-FWMKGIEWSA-L 0.000 abstract 1
229940051593 dermatan sulfate Drugs 0.000 abstract 1
238000000502 dialysis Methods 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003055 low molecular weight heparin Substances 0.000 abstract 1
229940127215 low-molecular weight heparin Drugs 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
230000032258 transport Effects 0.000 abstract 1
238000000108 ultra-filtration Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/37—Digestive system
- A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Epidemiology (AREA)
Molecular Biology (AREA)
Dermatology (AREA)
Cell Biology (AREA)
Engineering & Computer Science (AREA)
Developmental Biology & Embryology (AREA)
Immunology (AREA)
Biotechnology (AREA)
Virology (AREA)
Physiology (AREA)
Biomedical Technology (AREA)
Nutrition Science (AREA)
Zoology (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
External Artificial Organs (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

GR20010401009T 1994-10-06 2001-06-29 Use of some glycosaminoglycans for the manufacture of a medicament for the treatment of chronic renal failure GR3036158T3 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ITBO940436A IT1274351B (it)	1994-10-06	1994-10-06	Uso di alcuni glicosaminoglicani nella dialisi peritoneale.

Publications (1)

Publication Number	Publication Date
GR3036158T3 true GR3036158T3 (en)	2001-09-28

Family

ID=11340040

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GR20010401009T GR3036158T3 (en)	1994-10-06	2001-06-29	Use of some glycosaminoglycans for the manufacture of a medicament for the treatment of chronic renal failure

Country Status (9)

Country	Link
US (1)	US5686432A (el)
EP (1)	EP0710483B1 (el)
AT (1)	ATE202282T1 (el)
DE (1)	DE69521388T2 (el)
DK (1)	DK0710483T3 (el)
ES (1)	ES2157277T3 (el)
GR (1)	GR3036158T3 (el)
IT (1)	IT1274351B (el)
PT (1)	PT710483E (el)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IL127896A0 (en) *	1998-12-31	1999-10-28	Gail Laster	A novel treatment for preeclampsia and related diseases
JP2003504428A (ja) *	1999-06-30	2003-02-04	ハミルトンシビックホスピタルズリサーチディベロップメントインコーポレイテッド	クロット関連凝固因子を阻害するヘパリン組成物
ITMI991503A1 (it) *	1999-07-08	2001-01-08	Bidifarm S R L	Uso di metaboliti oligosaccaridici di proteoglicani come maker in fluidi biologici di diagnosi del biabete e delle complicanze patologiche c
US7259152B2 (en) *	2000-06-07	2007-08-21	Alfa Wasserman, Inc.	Methods and compositions using sulodexide for the treatment of diabetic nephropathy
AU2001291549A1 (en) *	2000-09-08	2002-03-22	Hamilton Civic Hospitals Research Development Inc.	Antithrombotic compositions
US20030008844A1 (en) *	2001-05-17	2003-01-09	Keryx Biopharmaceuticals, Inc.	Use of sulodexide for the treatment of inflammatory bowel disease
US20030013680A1 (en) *	2001-06-12	2003-01-16	Keryx	Methods using glycosaminoglycans for the treatment of nephropathy
PE20030263A1 (es) *	2001-07-31	2003-04-17	Novartis Ag	Composicion farmaceutica oftalmica
EP1890686B1 (en)	2005-05-30	2017-10-04	Fresenius Medical Care Deutschland GmbH	Peritoneal dialysis fluid
MX2008008213A (es)	2005-12-22	2008-09-03	Neurochem Int Ltd	Tratamiento de trastornos renales, nefropatia diabetica y dislipidemias.
US20070155672A1 (en) *	2006-01-05	2007-07-05	Markus Voges	Sterilized peritoneal dialysis solutions containing heparin
WO2009044765A1 (ja) *	2007-10-01	2009-04-09	Seikagaku Corporation	新規な低分子化コンドロイチン硫酸およびその用途
CN101632686A (zh) *	2008-04-04	2010-01-27	马斯特里赫特大学	糖胺聚糖用于修复糖萼的用途
IT1401253B1 (it)	2010-04-23	2013-07-18	Uni Degli Studi Carlo Bo Urbino	Uso del sulodexide per la riduzione delle metalloproteinasi di matrice.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1245907B (it) *	1991-05-17	1994-10-25	Alfa Wassermann Spa	Uso dei glicosaminoglicani nel trattamento della nefropatia diabetica e della neuropatia diabetica.
IT1270846B (it) *	1993-05-10	1997-05-13	Alfa Wassermann Spa	Uso di sulodexide e delle specialita' medicinali che lo contengono nel trattamento della nefropatia diabetica.
DE69429576T2 (de) *	1993-09-30	2002-08-22	Seikagaku Kogyo K.K., Tokio/Tokyo	Dermatansulfatezusammensetzung als antithromotisches mittel

1994
- 1994-10-06 IT ITBO940436A patent/IT1274351B/it active IP Right Grant
1995
- 1995-09-04 DK DK95113868T patent/DK0710483T3/da active
- 1995-09-04 AT AT95113868T patent/ATE202282T1/de active
- 1995-09-04 PT PT95113868T patent/PT710483E/pt unknown
- 1995-09-04 EP EP95113868A patent/EP0710483B1/en not_active Expired - Lifetime
- 1995-09-04 ES ES95113868T patent/ES2157277T3/es not_active Expired - Lifetime
- 1995-09-04 DE DE69521388T patent/DE69521388T2/de not_active Expired - Lifetime
- 1995-09-19 US US08/530,597 patent/US5686432A/en not_active Expired - Lifetime
2001
- 2001-06-29 GR GR20010401009T patent/GR3036158T3/el unknown

Also Published As

Publication number	Publication date
PT710483E (pt)	2001-09-28
ITBO940436A1 (it)	1996-04-06
ITBO940436A0 (it)	1994-10-06
EP0710483B1 (en)	2001-06-20
US5686432A (en)	1997-11-11
DK0710483T3 (da)	2001-09-03
ATE202282T1 (de)	2001-07-15
IT1274351B (it)	1997-07-17
DE69521388D1 (de)	2001-07-26
DE69521388T2 (de)	2001-10-11
EP0710483A1 (en)	1996-05-08
ES2157277T3 (es)	2001-08-16

Similar Documents

Publication	Publication Date	Title
DK0710483T3 (da)	2001-09-03	Anvendelse af visse glycosaminoglycaner til fremstillingen af et lægemiddel til behandlingen af kronisk nyresvigt
Amyot et al.	1999	Myoglobin clearance and removal during continuous venovenous hemofiltration
Taylor et al.	1991	Erythropoietin and spontaneous platelet aggregation in haemodialysis patients
Man et al.	1991	Phosphate removal during hemodialysis, hemodiafiltration, and hemofiltration A reappraisal
von Lilien et al.	1987	Five years' experience with continuous ambulatory or continuous cycling peritoneal dialysis in children
EP0824698A4 (en)	1999-04-14	DEVICE AND METHOD FOR BIOSPECIFIC ELIMINATION OF HEPARIN
Edefonti et al.	1999	Dietary prescription based on estimated nitrogen balance during peritoneal dialysis
Kierdorf et al.	1995	Continuous treatment modalities in acute renal failure
Briglia et al.	1999	Acute renal failure in the intensive care unit: therapy overview, patient risk stratification, complications of renal replacement, and special circumstances
Bunchman et al.	1999	Treatment of vancomycin overdose using high-efficiency dialysis membranes
Bellomo et al.	1992	Management of acute renal failure in the critically ill with continuous venovenous hemodiafiltration
Moncrief et al.	1994	Continuous ambulatory peritoneal dialysis
Gross et al.	1983	Ceftizoxime elimination kinetics in continuous ambulatory peritoneal dialysis
Koup et al.	1986	Ceftriaxone pharmacokinetics during peritoneal dialysis
Davies et al.	1991	Failure Treated by Continuous Arteriovenous Haemodialysis
Schrader et al.	1986	Long-term intraperitoneal application of low molecular weight heparin in a continuous ambulatory peritoneal dialysis patient with deep vein thrombosis
Bosworth et al.	1991	Long-Term Experience with Continuous Renal Replacement Therapy in Intensive-Care Unit
Boelaert et al.	1985	Effect of renal function and dialysis on temocillin pharmacokinetics
Gotloib et al.	1985	Hemofiltration in severe septic adult respiratory distress syndrome associated with varicella
Sigler et al.	1994	Continuous Renal Replacement Therapy in the Critically III Patient With Acute Renal Failure: Pros and Cons
Vaziri	1984	Long-term haemodialysis in spinal cord injured patients
Von Herrath et al.	1988	Good biocompatibility of the polyamide hemofilter
Bosch et al.	1993	Reverse flux filtration: a new mode of therapy improving the efficacy of heparin-induced extracorporeal LDL precipitation in hyperlipidemic hemodialysis patients
Riambau et al.	1980	Sequential Intraperitoneal Adkinistration of Nitroprusside in Patients Yaintained on Peritoneal Dialysis
Sieberth	1991	Continuous Hemofiltration: 2nd International Conferenc, Baden/Austria, September 1990