ATE204287T1 - Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten - Google Patents

Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten

Info

Publication number
ATE204287T1
ATE204287T1 AT94910741T AT94910741T ATE204287T1 AT E204287 T1 ATE204287 T1 AT E204287T1 AT 94910741 T AT94910741 T AT 94910741T AT 94910741 T AT94910741 T AT 94910741T AT E204287 T1 ATE204287 T1 AT E204287T1
Authority
AT
Austria
Prior art keywords
gangliosides
lyso
derivatives
acyl
new
Prior art date
Application number
AT94910741T
Other languages
English (en)
Inventor
Aurelio Romeo
Guenter Kirschner
Carlo Chizzolini
Hari Manev
Laura Facci
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Application granted granted Critical
Publication of ATE204287T1 publication Critical patent/ATE204287T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Vascular Medicine (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94910741T 1993-03-04 1994-03-04 Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten ATE204287T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT93PD000045A IT1267956B1 (it) 1993-03-04 1993-03-04 Derivati o-solfatati di gangliosidi e lisogangliosidi
PCT/US1994/001965 WO1994020515A1 (en) 1993-03-04 1994-03-04 New o-sulfated gangliosides and lyso-ganglioside derivatives

Publications (1)

Publication Number Publication Date
ATE204287T1 true ATE204287T1 (de) 2001-09-15

Family

ID=11390210

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94910741T ATE204287T1 (de) 1993-03-04 1994-03-04 Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten

Country Status (10)

Country Link
EP (1) EP0688330B1 (de)
JP (1) JPH08507307A (de)
KR (1) KR960701073A (de)
AT (1) ATE204287T1 (de)
AU (1) AU694105B2 (de)
CA (1) CA2157359A1 (de)
DE (1) DE69427966T2 (de)
ES (1) ES2159554T3 (de)
IT (1) IT1267956B1 (de)
WO (1) WO1994020515A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1267955B1 (it) * 1993-03-04 1997-02-18 Fidia S P A In Amministrazione Derivati solfatati dei lisogangliosidi
US8481711B2 (en) 2010-07-06 2013-07-09 Hidenori Kamanishi Neurite outgrowth agent

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1238346B (it) * 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.
JPH03246297A (ja) * 1990-02-22 1991-11-01 Nippon Koutai Kenkyusho:Kk ガングリオシド誘導体及びこれを含有する抗hiv剤
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi

Also Published As

Publication number Publication date
DE69427966D1 (de) 2001-09-20
WO1994020515A1 (en) 1994-09-15
CA2157359A1 (en) 1994-09-15
EP0688330B1 (de) 2001-08-16
ES2159554T3 (es) 2001-10-16
EP0688330A1 (de) 1995-12-27
IT1267956B1 (it) 1997-02-18
ITPD930045A0 (it) 1993-03-04
AU6352194A (en) 1994-09-26
ITPD930045A1 (it) 1994-09-04
JPH08507307A (ja) 1996-08-06
DE69427966T2 (de) 2002-04-04
AU694105B2 (en) 1998-07-16
KR960701073A (ko) 1996-02-24

Similar Documents

Publication Publication Date Title
ATE256137T1 (de) Keratansulfatoligosaccharid-fraktion und sie enthaltendes medikament
BE904431A (fr) Nouveaux derives morpholino de la daunorubicine et de la doxorubicine.
ATA195588A (de) Epipodophyllotoxinglucosid-4'-phosphat-derivate deren herstellung, sowie pharmazeutische zusammensetzungen hierzu
DE69319912D1 (de) Triantennar cluster glykoside, ihre herstellung und verwendung
ES2129037T3 (es) Heparosanos-n,o-sulfatados de alta masa molecular, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
PT88306A (pt) Processo para a preparacao de nucleosidos de 2', 3'-dideoxi-3'-fluoro-pirimidina e de composicoes farmaceuticas que os contem
DE69729958D1 (de) Verbindungen mit antiviraler aktivität
BR9508002A (pt) Preparado farmacêutico com uma substância ativa hidrófoba e um sistema efervecente, e processo para a produção do preparado
ATE204287T1 (de) Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten
DK333787D0 (da) Anvendelse af gangliosidderivater
DK0904299T3 (da) Syntetiske polysaccharider, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende sådanne polysaccharider
IT8821764A0 (it) Dispositivo di serraggio per mantenere in presa senza gioco due parti di albero nel senso di rotazione.
AU545885B2 (en) Oral absorption of glycosidic antibiotics
BE902774A (fr) Diacyloxy-1,8 acyl-10 anthrones procede de preparation et utilisation en medecine humaine ou veterinaire et en cosmetique.
BE905751A (fr) Nitro-anthracycline, aglycone correspondante, procedes pour les preparer, composition pharmaceutique correspondante.
ATE186054T1 (de) Glykoside, deren zuckerfreie abbauprodukte und derivate derselben
IT1236584B (it) Uso di gangliosidi nel trattamento della disfunzione autonomica nel morbo di chagas
FR2361392A1 (fr) Nouveaux 2,2-diaryl-3-(1-aza-2-bicyclo(2.2.2)octyl)propionamides utiles notamment comme agents antidiarrheiques et leur procede de preparation
FR2572080B1 (fr) Procede de preparation de compositions de mucopolysaccharides dotees d'une activite antithrombotique elevee, les compositions obtenues et leur application en tant que medicaments
FAN et al. Isolation, Purification and its antitumor activity of glycosaminoglycan from Pinctada martensii
IT1258310B (it) Composizioni farmaceutiche comprendenti derivati monosialogangliosidici atte al trattamento del danno al midollo spinale.
SE8501666L (sv) Antracyklinderivat, forfaranden for framstellning derav samt farmaceutisk komposition innehallande dem
ITPD920190A1 (it) Composizioni farmaceutiche comprendenti gangliosidi o derivati gangliosidici atte al trattamento di condizioni patologiche caratte-

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties