ATE204287T1 - Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten - Google Patents

Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten

Info

Publication number
ATE204287T1
ATE204287T1 AT94910741T AT94910741T ATE204287T1 AT E204287 T1 ATE204287 T1 AT E204287T1 AT 94910741 T AT94910741 T AT 94910741T AT 94910741 T AT94910741 T AT 94910741T AT E204287 T1 ATE204287 T1 AT E204287T1
Authority
AT
Austria
Prior art keywords
gangliosides
lyso
derivatives
acyl
new
Prior art date
Application number
AT94910741T
Other languages
English (en)
Inventor
Aurelio Romeo
Guenter Kirschner
Carlo Chizzolini
Hari Manev
Laura Facci
Original Assignee
Fidia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fidia Spa filed Critical Fidia Spa
Application granted granted Critical
Publication of ATE204287T1 publication Critical patent/ATE204287T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94910741T 1993-03-04 1994-03-04 Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten ATE204287T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT93PD000045A IT1267956B1 (it) 1993-03-04 1993-03-04 Derivati o-solfatati di gangliosidi e lisogangliosidi
PCT/US1994/001965 WO1994020515A1 (en) 1993-03-04 1994-03-04 New o-sulfated gangliosides and lyso-ganglioside derivatives

Publications (1)

Publication Number Publication Date
ATE204287T1 true ATE204287T1 (de) 2001-09-15

Family

ID=11390210

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94910741T ATE204287T1 (de) 1993-03-04 1994-03-04 Neue o-sulfatierte ganglioside und lyso- ganglioside-derivaten

Country Status (10)

Country Link
EP (1) EP0688330B1 (de)
JP (1) JPH08507307A (de)
KR (1) KR960701073A (de)
AT (1) ATE204287T1 (de)
AU (1) AU694105B2 (de)
CA (1) CA2157359A1 (de)
DE (1) DE69427966T2 (de)
ES (1) ES2159554T3 (de)
IT (1) IT1267956B1 (de)
WO (1) WO1994020515A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1267955B1 (it) * 1993-03-04 1997-02-18 Fidia S P A In Amministrazione Derivati solfatati dei lisogangliosidi
WO2012004917A1 (ja) 2010-07-06 2012-01-12 Kaminishi Hidenori 神経突起伸長剤

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1238346B (it) * 1989-11-14 1993-07-13 Gangliosidi modificati e loro derivati funzionali.
JPH03246297A (ja) * 1990-02-22 1991-11-01 Nippon Koutai Kenkyusho:Kk ガングリオシド誘導体及びこれを含有する抗hiv剤
IT1253832B (it) * 1991-08-01 1995-08-29 Fidia Spa Derivati di gangliosidi

Also Published As

Publication number Publication date
EP0688330A1 (de) 1995-12-27
AU694105B2 (en) 1998-07-16
ITPD930045A0 (it) 1993-03-04
ITPD930045A1 (it) 1994-09-04
AU6352194A (en) 1994-09-26
EP0688330B1 (de) 2001-08-16
DE69427966D1 (de) 2001-09-20
IT1267956B1 (it) 1997-02-18
JPH08507307A (ja) 1996-08-06
WO1994020515A1 (en) 1994-09-15
ES2159554T3 (es) 2001-10-16
DE69427966T2 (de) 2002-04-04
CA2157359A1 (en) 1994-09-15
KR960701073A (ko) 1996-02-24

Similar Documents

Publication Publication Date Title
ATE256137T1 (de) Keratansulfatoligosaccharid-fraktion und sie enthaltendes medikament
BE904431A (fr) Nouveaux derives morpholino de la daunorubicine et de la doxorubicine.
DE3686975D1 (de) Zusammensetzung auf basis von glucomannanen und polyhydrischen alkoholen und daraus hergestellter film.
ATA195588A (de) Epipodophyllotoxinglucosid-4'-phosphat-derivate deren herstellung, sowie pharmazeutische zusammensetzungen hierzu
FR2374910A1 (fr) Preparation a base d'heparine, comprenant des liposomes, procede pour l'obtenir et medicaments contenant de telles preparations
DK0655070T3 (da) Triantennære klusterglycosider, deres fremstilling og anvendelse
ES2129037T3 (es) Heparosanos-n,o-sulfatados de alta masa molecular, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
BR0014939A (pt) Oligossacarìdeos, processo de preparação de oligossacarìdeos, composições farmacêuticas, e, utilização de oligossacarìdeos
DE69032722D1 (de) Modifizierte Ganglioside und ihre funktionellen Derivate
PT88306A (pt) Processo para a preparacao de nucleosidos de 2', 3'-dideoxi-3'-fluoro-pirimidina e de composicoes farmaceuticas que os contem
DE69729958D1 (de) Verbindungen mit antiviraler aktivität
BR9508002A (pt) Preparado farmacêutico com uma substância ativa hidrófoba e um sistema efervecente, e processo para a produção do preparado
DE69427966D1 (de) Neue o-sulfatierte ganglioside und lyso-ganglioside-derivaten
DK333787D0 (da) Anvendelse af gangliosidderivater
NO965483L (no) Dinukleosid-5',5'-pyrofosfater
ITMI920591A1 (it) Composizioni farmaceutiche comprendenti monosialoganglioside gm1 o un suo derivato atte al trattamento della malattia di parkinson
DK0904299T3 (da) Syntetiske polysaccharider, fremgangsmåde til fremstilling heraf og farmaceutiske sammensætninger indeholdende sådanne polysaccharider
IT8821764A0 (it) Dispositivo di serraggio per mantenere in presa senza gioco due parti di albero nel senso di rotazione.
AU545885B2 (en) Oral absorption of glycosidic antibiotics
BE902774A (fr) Diacyloxy-1,8 acyl-10 anthrones procede de preparation et utilisation en medecine humaine ou veterinaire et en cosmetique.
BE905751A (fr) Nitro-anthracycline, aglycone correspondante, procedes pour les preparer, composition pharmaceutique correspondante.
IT1236584B (it) Uso di gangliosidi nel trattamento della disfunzione autonomica nel morbo di chagas
FR2361392A1 (fr) Nouveaux 2,2-diaryl-3-(1-aza-2-bicyclo(2.2.2)octyl)propionamides utiles notamment comme agents antidiarrheiques et leur procede de preparation
FR2572080B1 (fr) Procede de preparation de compositions de mucopolysaccharides dotees d'une activite antithrombotique elevee, les compositions obtenues et leur application en tant que medicaments
IT1258310B (it) Composizioni farmaceutiche comprendenti derivati monosialogangliosidici atte al trattamento del danno al midollo spinale.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties