ATE204607T1 - Oberflächen lokalisierte expressionsbanken von heteromeren rezeptoren - Google Patents

Oberflächen lokalisierte expressionsbanken von heteromeren rezeptoren

Info

Publication number
ATE204607T1
ATE204607T1 AT91918234T AT91918234T ATE204607T1 AT E204607 T1 ATE204607 T1 AT E204607T1 AT 91918234 T AT91918234 T AT 91918234T AT 91918234 T AT91918234 T AT 91918234T AT E204607 T1 ATE204607 T1 AT E204607T1
Authority
AT
Austria
Prior art keywords
heteromeric receptors
surface localized
localized expression
heteromeric
expression banks
Prior art date
Application number
AT91918234T
Other languages
English (en)
Inventor
William D Huse
Original Assignee
Ixsys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24361342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE204607(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ixsys Inc filed Critical Ixsys Inc
Application granted granted Critical
Publication of ATE204607T1 publication Critical patent/ATE204607T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00—Libraries per se, e.g. arrays, mixtures
    • C40B40/02—Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034—Isolating an individual clone by screening libraries
    • C12N15/1037—Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735—Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00—Bacteriophages
    • C12N2795/00011—Details
    • C12N2795/14011—Details ssDNA Bacteriophages
    • C12N2795/14022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Cell Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT91918234T 1990-09-28 1991-09-27 Oberflächen lokalisierte expressionsbanken von heteromeren rezeptoren ATE204607T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59021990A 1990-09-28 1990-09-28
PCT/US1991/007149 WO1992006204A1 (en) 1990-09-28 1991-09-27 Surface expression libraries of heteromeric receptors

Publications (1)

Publication Number Publication Date
ATE204607T1 true ATE204607T1 (de) 2001-09-15

Family

ID=24361342

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91918234T ATE204607T1 (de) 1990-09-28 1991-09-27 Oberflächen lokalisierte expressionsbanken von heteromeren rezeptoren

Country Status (11)

Country Link
EP (1) EP0550645B1 (de)
JP (1) JP3373510B2 (de)
AT (1) ATE204607T1 (de)
AU (1) AU667291B2 (de)
CA (1) CA2092802A1 (de)
DE (1) DE69132700T2 (de)
IE (1) IE63054B1 (de)
IL (1) IL99552A0 (de)
NZ (1) NZ239988A (de)
TW (1) TW314553B (de)
WO (1) WO1992006204A1 (de)

Families Citing this family (857)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US7413537B2 (en) 1989-09-01 2008-08-19 Dyax Corp. Directed evolution of disulfide-bonded micro-proteins
US5498538A (en) * 1990-02-15 1996-03-12 The University Of North Carolina At Chapel Hill Totally synthetic affinity reagents
US5747334A (en) * 1990-02-15 1998-05-05 The University Of North Carolina At Chapel Hill Random peptide library
US5427908A (en) * 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9206318D0 (en) * 1992-03-24 1992-05-06 Cambridge Antibody Tech Binding substances
US7063943B1 (en) 1990-07-10 2006-06-20 Cambridge Antibody Technology Methods for producing members of specific binding pairs
US6172197B1 (en) 1991-07-10 2001-01-09 Medical Research Council Methods for producing members of specific binding pairs
US6916605B1 (en) 1990-07-10 2005-07-12 Medical Research Council Methods for producing members of specific binding pairs
GB9015198D0 (en) * 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
DE69233697T2 (de) 1991-03-01 2008-01-24 Dyax Corp., Cambridge Verfahren zur Entwicklung von bindenden Mikroproteinen
PT100379B (pt) * 1991-04-10 1999-01-29 Scripps Research Inst Bibliotecas de receptores heterodimericos usando fagomideos
US5858657A (en) * 1992-05-15 1999-01-12 Medical Research Council Methods for producing members of specific binding pairs
US5871907A (en) 1991-05-15 1999-02-16 Medical Research Council Methods for producing members of specific binding pairs
US6492160B1 (en) 1991-05-15 2002-12-10 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
US5962255A (en) * 1992-03-24 1999-10-05 Cambridge Antibody Technology Limited Methods for producing recombinant vectors
US6225447B1 (en) 1991-05-15 2001-05-01 Cambridge Antibody Technology Ltd. Methods for producing members of specific binding pairs
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
US5733731A (en) * 1991-10-16 1998-03-31 Affymax Technologies N.V. Peptide library and screening method
PT1024191E (pt) 1991-12-02 2008-12-22 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
US5733743A (en) * 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
WO1994005781A1 (en) * 1992-09-04 1994-03-17 The Scripps Research Institute Phagemids coexpressing a surface receptor and a surface heterologous protein
DE69334261D1 (de) * 1992-11-10 2009-03-19 Applied Molecular Evolution Lösliche peptide, welche eine erzwungene sekundärstruktur in lösung haben und methode zur herstellung derselben
ZA938243B (en) * 1992-11-12 1995-05-04 Hybritech Inc Altered affinity polypeptides of metal chelate binding antibodies
WO1994018221A1 (en) 1993-02-02 1994-08-18 The Scripps Research Institute Methods for producing polypeptide binding sites
IT1270939B (it) * 1993-05-11 1997-05-26 Angeletti P Ist Richerche Bio Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
US7368111B2 (en) 1995-10-06 2008-05-06 Cambridge Antibody Technology Limited Human antibodies specific for TGFβ2
US6537776B1 (en) 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
US6096548A (en) 1996-03-25 2000-08-01 Maxygen, Inc. Method for directing evolution of a virus
EA199900355A1 (ru) 1996-10-01 2000-08-28 Джерон Корпорейшн Теломераза обратная тринскриптаза
UA75316C2 (uk) 1996-10-16 2006-04-17 Займодженетікс, Інк. Гомологи з фактором росту фібробласта
US6310191B1 (en) 1998-02-02 2001-10-30 Cosmix Molecular Biologicals Gmbh Generation of diversity in combinatorial libraries
CN1246150A (zh) * 1997-01-31 2000-03-01 科斯米克斯分子生物有限公司 组合文库的多样性的产生
US6555310B1 (en) 1997-04-04 2003-04-29 Biosite Diagnostics, Inc. Polyclonal libraries
US6057098A (en) 1997-04-04 2000-05-02 Biosite Diagnostics, Inc. Polyvalent display libraries
AU1449499A (en) 1997-10-31 1999-05-24 Maxygen, Incorporated Modification of virus tropism and host range by viral genome shuffling
US7390619B1 (en) 1998-02-11 2008-06-24 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
DE19816129A1 (de) * 1998-04-09 1999-10-14 Dolores Schendel T-Zellrezeptor-Expressionskassette
EP2284272B1 (de) 1998-06-10 2014-08-13 Novozymes A/S Mannanasen
US6190908B1 (en) * 1998-08-12 2001-02-20 The Scripps Research Institute Modulation of polypeptide display on modified filamentous phage
DE69939330D1 (de) 1998-12-07 2008-09-25 Zymogenetics Inc Wachstumsfaktor-homologe zvegf-3
CZ303272B6 (cs) 1999-01-07 2012-07-11 Zymogenetics, Inc. Farmaceutický prostredek obsahující fúzní protein, izolovaná molekula polynukleotidu, expresní vektor, kultivovaná bunka, zpusob prípravy polypeptidu a izolovaný polypeptid
AU3391900A (en) 1999-03-05 2000-09-21 Maxygen, Inc. Encryption of traits using split gene sequences
UA84387C2 (ru) 1999-03-09 2008-10-27 Займодженетикс, Инк. Человеческий цитокин как лиганд зальфа рецептора и его применение
US6492497B1 (en) 1999-04-30 2002-12-10 Cambridge Antibody Technology Limited Specific binding members for TGFbeta1
DE60034564T2 (de) 1999-07-07 2007-12-27 Zymogenetics, Inc., Seattle Menschlicher cytokinrezeptor
US7135287B1 (en) 1999-10-02 2006-11-14 Biosite, Inc. Human antibodies
US6794132B2 (en) 1999-10-02 2004-09-21 Biosite, Inc. Human antibodies
US6680209B1 (en) 1999-12-06 2004-01-20 Biosite, Incorporated Human antibodies as diagnostic reagents
EP2194130A1 (de) 1999-12-23 2010-06-09 ZymoGenetics, L.L.C. Zytokin ZCYT018
ES2279809T3 (es) 2000-04-05 2007-09-01 Zymogenetics, Inc. Receptores de citoquina zalfa11 solubles.
WO2001087933A2 (en) 2000-05-11 2001-11-22 Zymogenetics, Inc. Zsig33-like peptides
EP1325115B1 (de) 2000-06-26 2016-07-27 ZymoGenetics, Inc. Cytokinrezeptor zcytor17
JP2005506042A (ja) 2000-12-12 2005-03-03 ユニヴァーシティー オブ コネティカット 細胞トランスポーターをコードするポリヌクレオチド、およびその使用方法
US7309783B2 (en) 2001-05-09 2007-12-18 The University Of Connecticut Mammalian early developmental regulator gene
AU2002311012A1 (en) 2001-06-06 2002-12-16 Novozymes A/S Endo-beta-1,4-glucanase from bacillus
EP2130919A1 (de) 2001-11-05 2009-12-09 ZymoGenetics, Inc. IL-21-Antagonisten
WO2004003140A2 (en) 2002-01-18 2004-01-08 Zymogenetics, Inc. Cytokine receptor zcytor17 multimers
RU2490276C2 (ru) 2002-01-18 2013-08-20 Займоджинетикс, Инк. Новый лиганд рецептора цитокина zcytor17
US7094579B2 (en) 2002-02-13 2006-08-22 Xoma Technology Ltd. Eukaryotic signal sequences for prokaryotic expression
CN1659274A (zh) 2002-04-19 2005-08-24 津莫吉尼蒂克斯公司 细胞因子受体
MXPA04012116A (es) 2002-06-07 2005-04-19 Zymogenetics Inc Uso del il-21 en cancer y otras aplicaciones terapeuticas.
AU2003274463B2 (en) 2002-06-10 2009-10-29 University Of Rochester Gene differentially expressed in breast and bladder cancer and encoded polypeptides
US7939304B2 (en) 2002-10-02 2011-05-10 Catalyst Biosciences, Inc. Mutant MT-SP1 proteases with altered substrate specificity or activity
WO2004031733A2 (en) 2002-10-02 2004-04-15 Catalyst Biosciences Methods of generating and screenign for porteases with altered specificity
EP1947116B1 (de) 2003-02-10 2017-06-21 2-BBB Medicines B.V. Differenziell exprimierte Nukleinsäuren der Blut-Hirnschranke bei einer Entzündung
ATE471370T1 (de) 2003-05-02 2010-07-15 Novozymes Inc Varianten von beta-glukosidasen
US9708410B2 (en) 2003-05-30 2017-07-18 Janssen Biotech, Inc. Anti-tissue factor antibodies and compositions
EP1653995A1 (de) 2003-08-08 2006-05-10 Novo Nordisk A/S Interleukin-20 zur behandlung und diagnose von mit neovaskularization verbunden zuständen
ES2538824T3 (es) 2003-08-25 2015-06-24 Novozymes, Inc. Variantes de glucósido hidrolasas
ES2428358T3 (es) 2003-10-17 2013-11-07 Novo Nordisk A/S Terapia de combinación
DK1682656T3 (da) 2003-10-28 2013-11-18 Novozymes Inc Polypeptider med beta-glucosidaseaktivitet og polynukleotider, der koder for dem
DK1713825T3 (da) 2004-01-30 2012-11-05 Novozymes Inc Polypeptider med cellulolytisk forøgende aktivitet og polynukleotider der koder for samme
WO2006078256A2 (en) 2004-02-12 2006-07-27 Novozymes, Inc. Polypeptides having xylanase activity and polynucleotides encoding same
WO2005110453A2 (en) 2004-04-12 2005-11-24 Catalyst Biosciences, Inc. Cleavage of vegf and vegf receptor by wildtype and mutant mt-sp1
WO2005121351A2 (en) 2004-05-27 2005-12-22 Novozymes, Inc. Methods for transforming and expression screening of filamentous fungal cells with a dna library
WO2006005032A2 (en) 2004-06-29 2006-01-12 Novozymes, Inc. Polypeptides having alpha-glucosidase activity and polynucleotides encoding same
US7666630B2 (en) 2004-09-30 2010-02-23 Novozymes, Inc. Polypeptides having lipase activity and polynucleotides encoding same
EP1809747B1 (de) 2004-10-04 2016-12-14 Novozymes A/S Polypeptide mit phytaseaktivität und dafür codierende polynukleotide
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
EP1814996A2 (de) 2004-11-19 2007-08-08 Novozymes A/S Polypeptide mit antimikrobieller aktivität und diese codierende polynukleotide
MX2007007107A (es) 2004-12-22 2007-08-08 Novozymes North America Inc Polipeptidos que tienen actividad de glucoamilasa y polinucleotidos que los codifican.
WO2006086396A2 (en) 2005-02-08 2006-08-17 Zymogenetics, Inc. Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation
AR052947A1 (es) 2005-03-18 2007-04-11 Novozymes As Polipeptidos que tienen actividad antimicrobiana y polinucleotidos que codifican para los mismos
AU2006226192A1 (en) 2005-03-19 2006-09-28 Medical Research Council Improvements in or relating to treatment and prevention of viral infections
CA2606475C (en) 2005-04-27 2015-06-16 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
EP3683230A1 (de) 2005-05-12 2020-07-22 ZymoGenetics, Inc. Zusammensetzungen und verfahren zur modulation von immunsystemreaktionen
WO2007001677A2 (en) 2005-05-17 2007-01-04 University Of Connecticut Compositions and methods for immunomodulation in an organism
AU2006283904B2 (en) 2005-08-26 2012-07-12 Novozymes Adenium Biotech A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
EP1941023B1 (de) 2005-09-30 2017-04-05 Novozymes Inc. Verfahren zur verstärkung des verfalls oder der umwandlung von cellulose-material
EP1999257B1 (de) 2006-03-20 2011-06-22 Novozymes, Inc. Polypeptide mit endoglucanase-aktivität und polynukleotide zu ihrer kodierung
EP2004817A2 (de) 2006-03-30 2008-12-24 Novozymes, Inc. Polypeptide mit endoglucanase-aktivität und polynukleotide zu ihrer kodierung
US8106013B2 (en) 2006-05-19 2012-01-31 Georgia Tech Research Corporation ABC transporter ligand GATX1
US7932055B2 (en) 2006-06-22 2011-04-26 Novo Nordisk A/S Soluble heterodimeric CD94/NKG2 receptors fusion proteins
US8324158B2 (en) 2006-07-14 2012-12-04 Georgia Tech Research Corporation Methods for inhibiting CLC-2 channel with GATX2
CN101522045A (zh) 2006-09-29 2009-09-02 诺维信公司 用于动物饲料的木聚糖酶
EP2099818A2 (de) 2006-11-29 2009-09-16 Novozymes Inc. Bacillus licheniformis-chromosom
CN101595214B (zh) 2006-11-29 2013-06-12 诺维信股份有限公司 改进向细菌细胞中导入dna的方法
PL2662091T3 (pl) 2006-12-01 2019-05-31 Novartis Ag Przeciwciała skierowane przeciwko selektynie P i sposoby ich zastosowania do leczenia chorób zapalnych
DK2129781T3 (da) 2007-03-26 2014-03-31 Novozymes As Hafnia-phytase
DE102007016139A1 (de) 2007-03-30 2008-10-02 Jenabios Gmbh Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen
EP2193195B1 (de) 2007-09-18 2014-12-17 Novozymes A/S Polypeptide mit tyrosinaseaktivität und für diese kodierende polynukleotide
US7858759B2 (en) 2007-10-04 2010-12-28 Zymogenetics, Inc. Anti-zB7H6 antibody-drug conjugates
CN101918437B (zh) 2007-11-21 2013-08-14 罗斯基勒大学 具有冰结合活性的多肽
US7867745B2 (en) 2007-11-27 2011-01-11 Novozymes A/S Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same
CA2706639A1 (en) 2007-11-29 2009-06-04 Novozymes A/S Synthase inhibitor screening method
ES2490608T3 (es) 2007-12-06 2014-09-04 Novozymes A/S Polipéptidos con actividad de esterasa de acetilxilano y polinucleótidos que codifican los mismos
EP2235173A2 (de) 2007-12-19 2010-10-06 Novozymes A/S Polypeptide mit verstärkter zelluloseabbauender wirkung und dafür kodierende polynukleotide
NZ586544A (en) 2007-12-26 2012-07-27 Vaccinex Inc Anti-c35 antibody in combination with an ani-her2 antibody in cancer therapies and methods
KR101720760B1 (ko) 2008-01-25 2017-03-28 오르후스 우니베르시테트 Ｉｇｆｂｐ-4에 대한 ｐａｐｐ-ａ 활성의 선택적 엑소사이트 억제
JP5639039B2 (ja) 2008-04-11 2014-12-10 メリマック ファーマシューティカルズ インコーポレーティッド ヒト血清アルブミンリンカーおよびそのコンジュゲート
AU2009254546B2 (en) 2008-06-06 2014-09-25 Novozymes A/S Variants of a family 44 xyloglucanase
EP4545638A3 (de) 2008-06-06 2025-07-16 The Procter & Gamble Company Waschmittelzusammensetzung mit einer variante einer xyloglucanase der familie 44
JP5728380B2 (ja) 2008-06-12 2015-06-03 シンタクシン リミテッドＳｙｎｔａｘｉｎ Ｌｉｍｉｔｅｄ 神経内分泌疾患の抑制
BRPI0915142A8 (pt) 2008-06-12 2018-01-02 Syntaxin Ltd Polipeptídeos, ácido nucleico e usos dos mesmos
WO2009158696A1 (en) 2008-06-27 2009-12-30 Zymogenetics, Inc. SOLUBLE HYBRID Fcγ RECEPTORS AND RELATED METHODS
CN102159233A (zh) 2008-07-18 2011-08-17 诺维信阿德宁生物技术公司 使用哺乳动物β防御素的炎性肠病的治疗
MX2011001409A (es) 2008-08-14 2011-03-29 Cephalon Australia Pty Ltd Anticuerpos anti-il-12/il-23.
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
WO2010059413A2 (en) 2008-11-20 2010-05-27 Novozymes, Inc. Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
US7771983B2 (en) 2008-12-04 2010-08-10 Novozymos, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2010068800A1 (en) 2008-12-12 2010-06-17 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
US20110296557A1 (en) 2008-12-12 2011-12-01 Novozymes, Inc. Polypeptides Having Lipase Activity And Polynucleotides Encoding Same
WO2010074972A1 (en) 2008-12-15 2010-07-01 Novozymes, Inc. Polypeptides having catalase activity and polynucleotides encoding same
US20110271407A1 (en) 2008-12-16 2011-11-03 Novozymes, Inc. Polypeptides Having Alpha-Mannosidase Activity And Polynucleotides Encoding Same
WO2010074955A1 (en) 2008-12-16 2010-07-01 Novozymes, Inc. Polypeptides having carboxypeptidase activity and polynucleotides encoding same
EP2379729A2 (de) 2008-12-19 2011-10-26 Novozymes A/S Verwendung von enzymen mit silicase-aktivität
CN102361973B (zh) 2009-01-21 2015-09-02 诺维信公司 具有酯酶活性的多肽和编码该多肽的核酸
WO2010088387A1 (en) 2009-01-28 2010-08-05 Novozymes, Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
WO2010087702A1 (en) 2009-01-30 2010-08-05 Stichting Katholieke Universiteit TET2 gene as a marker for diagnosing a myelodysuplastic syndrome (MDS) or an acute myeloid leukemia (AML) and determining the prognosis in a subject
WO2010088447A1 (en) 2009-01-30 2010-08-05 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
WO2010088463A2 (en) 2009-01-30 2010-08-05 Novozymes, Inc. Polypeptides having expansin activity and polynucleotides encoding same
US8679814B2 (en) 2009-02-06 2014-03-25 University Of Chile Protein and DNA sequence encoding a cold adapted xylanase
WO2010091221A1 (en) 2009-02-06 2010-08-12 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
SG172789A1 (en) 2009-02-11 2011-08-29 Novozymes Biopharma Dk As Albumin variants and conjugates
WO2010097436A1 (en) 2009-02-27 2010-09-02 Novozymes A/S Mutant cells having reduced expression of metallopeptidase, suitable for recombinant polypeptide production
EP2408314A1 (de) 2009-03-17 2012-01-25 Novozymes A/S Polypeptide mit tyrosinaseaktivität und für diese codierende polynukleotide
CN102365360A (zh) 2009-03-24 2012-02-29 诺维信公司 具有乙酰木聚糖酯酶活性的多肽和编码该多肽的多核苷酸
EP2248893A1 (de) 2009-05-06 2010-11-10 Novozymes A/S DFPase-Enzyme aus Octopus Vulgaris
EP2435561B1 (de) 2009-05-29 2018-08-08 Novozymes Inc. Verfahren zur verbesserung des abbaus oder der umwandlung von cellulosematerial
ES2534078T3 (es) 2009-06-02 2015-04-17 Novozymes Inc. Polipéptidos con actividad de celobiohidrolasa y polinucleótidos que codifican los mismos
WO2010151787A1 (en) 2009-06-26 2010-12-29 Novozymes North America, Inc. Heat-stable carbonic anhydrases and their use
CA2767169A1 (en) 2009-07-07 2011-01-13 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
MX2012001060A (es) 2009-07-24 2012-03-14 Novozymes As Carbohidrato-oxidasas.
WO2011014458A1 (en) 2009-07-28 2011-02-03 Novozymes, Inc. Polypeptides having phytase activity and polynucleotides encoding same
US8409830B2 (en) 2009-08-21 2013-04-02 Novozymes A/S Polypeptides having isoamylase activity and methods of use
US8741611B2 (en) 2009-09-01 2014-06-03 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
WO2011034421A1 (en) 2009-09-16 2011-03-24 Stichting Het Nederlands Kanker Instituut Fra-1 target genes as drug targets for treating cancer
DK3269804T3 (da) 2009-09-17 2020-11-23 Novozymes Inc Polypeptider med cellulolyseforbedrende aktivitet og polynukleotider, som koder for dem
EP2478095A1 (de) 2009-09-18 2012-07-25 Novozymes Inc. Polypeptide mit beta-glucosidase-aktivität und dafür kodierende polynukleotide
EP2305717A1 (de) 2009-09-21 2011-04-06 Koninklijke Nederlandse Akademie van Wetenschappen Hemmung von TNIK zur Behandlung von Darmkrebs
CN102648277B (zh) 2009-09-25 2015-05-20 诺维信公司 蛋白酶变体的用途
US9598692B2 (en) 2009-09-25 2017-03-21 University Of Oslo Multivalent phage display systems and methods
EP2480650B1 (de) 2009-09-25 2017-03-22 Novozymes A/S Subtilasevarianten
WO2011041397A1 (en) 2009-09-29 2011-04-07 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CA2775347A1 (en) 2009-09-29 2011-04-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
BR112012007375A2 (pt) 2009-09-30 2016-11-22 Novozymes As polipeptídeo isolado, polinucleotídeo isolado, métodos para produzir um polipeptídeo, para produzir um mutante de uma célula precursora, para inibir a expressão de um polipeptídeo, para produzir uma proteína, para degradar ou converter um material celulósico, para produzir um produto de fermentação e para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta transformada, molécula de rna inibitória de filamento duplo, e, composição detergente
WO2011039319A1 (en) 2009-09-30 2011-04-07 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2011050037A1 (en) 2009-10-23 2011-04-28 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
WO2011059740A1 (en) 2009-10-29 2011-05-19 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
AU2010311332B2 (en) 2009-10-30 2015-04-23 Albumedix Ltd. Albumin variants
DK2496692T3 (en) 2009-11-06 2016-06-27 Novozymes Inc POLYPEPTIDES WITH xylanase AND POLYNUCLEOTIDES ENCODING THEM
CN103068976A (zh) 2009-11-06 2013-04-24 诺维信股份有限公司 具有纤维二糖水解酶活性的多肽和编码该多肽的多核苷酸
EP2325311A1 (de) 2009-11-18 2011-05-25 Pierre Fabre Medicament Neuer Phagenanzeigevektor
CN102869770B (zh) 2009-11-30 2015-12-16 诺维信公司 具有葡糖淀粉酶活性的多肽和编码该多肽的多核苷酸
CA2782154C (en) 2009-11-30 2018-10-16 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
CA2782036C (en) 2009-12-01 2019-01-15 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
TW201125577A (en) 2009-12-02 2011-08-01 Novozymes As Use of defensins for treatment of infective endocarditis
WO2011067349A1 (en) 2009-12-03 2011-06-09 Novozymes A/S Variants of a polypeptide with lipolytic activity and improved stability
US8951770B2 (en) 2009-12-09 2015-02-10 Novozymes A/S GH8 xylanase variants
US8653024B2 (en) 2009-12-11 2014-02-18 Adenium Biotech Aps Use of AMPs for treatment of UTI/cystitis
US20120220513A1 (en) 2009-12-29 2012-08-30 Novozymes A/S Polypeptides Having Detergency Enhancing Effect
CN102884183B (zh) 2010-01-04 2015-09-16 诺维信公司 趋于钙耗竭和酸性pH的α-淀粉酶的稳定化
EP2354244A1 (de) 2010-02-04 2011-08-10 Stichting Top Institute Food and Nutrition MBL2 als Marker für die leberspezifische Insulinresistenz
EP2354245A1 (de) 2010-02-04 2011-08-10 Stichting Top Institute Food and Nutrition MBL2 als Marker für die hepatische PPAR-Aktivität
JP5833576B2 (ja) 2010-02-25 2015-12-16 ノボザイムス アクティーゼルスカブ リゾチームの変異体及びそれをコードするポリヌクレオチド
WO2011104284A1 (en) 2010-02-25 2011-09-01 Novozymes A/S Polypeptides having antimicrobial activity
WO2011109524A2 (en) 2010-03-03 2011-09-09 Novozymes, Inc. Xylanase variants and polynucleotides encoding same
US9222109B2 (en) 2010-03-28 2015-12-29 Novozymes A/S Enzymatic hydroxylation of aliphatic hydrocarbon
CN102834521B (zh) 2010-03-30 2018-02-27 诺维信公司 用于增强来自发酵工艺副产物的方法
WO2011123450A1 (en) 2010-03-31 2011-10-06 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
CA2795806C (en) 2010-04-14 2019-01-08 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
WO2011153317A1 (en) 2010-06-04 2011-12-08 Novozymes, Inc. C4 dicarboxylic acid production in filamentous fungi
EP2580238A1 (de) 2010-06-09 2013-04-17 Zymogenetics, Inc. Dimere vstm3-fusionsproteine sowie zugehörige zusammensetzungen und verfahren
WO2012047324A2 (en) 2010-06-10 2012-04-12 President And Fellows Of Harvard College Systems and methods for amplification and phage display
US8835604B2 (en) 2010-06-12 2014-09-16 Adenium Biotech Aos Antimicrobial peptide variants and polynucleotides encoding same
IN2013CN00459A (de) 2010-06-21 2015-07-03 Novozymes Inc
AU2011271094B2 (en) 2010-06-21 2015-01-22 Novozymes, Inc. Aspergillus aculeatus derived polypeptides having C4-dicarboxylic acid transporter activity and polynucleotides encoding same
EP2588604B1 (de) 2010-06-30 2016-06-29 Novozymes, Inc. Polypeptide mit beta-glucosidase-aktivität und dafür kodierende polynukleotide
WO2012021401A1 (en) 2010-08-12 2012-02-16 Novozymes, Inc. Compositions comprising a polypeptide having cellulolytic enhancing activity and a bicyclic compound and uses thereof
MX2013001843A (es) 2010-08-17 2013-06-28 Stichting Katholieke Univ Un metodo novedoso para el diagnostico de fiebre q usando una prueba inmunologica celular.
CN107299095B (zh) 2010-08-24 2021-05-11 诺维信公司 热稳定性Persephonella碳酸酐酶及其用途
WO2012030811A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2012030849A1 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
US8629325B2 (en) 2010-08-30 2014-01-14 Novozymes A/S Polypeptides having beta-glucosidase activity and polynucleotides encoding same
US9303074B2 (en) 2010-08-30 2016-04-05 Novoyzmes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2012030858A2 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having hemicellulolytic activity and polynucleotides encoding same
US9267126B2 (en) 2010-08-30 2016-02-23 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
EP2616483A1 (de) 2010-09-16 2013-07-24 Novozymes A/S Lysozyme
CA2811678C (en) 2010-09-21 2019-10-01 Stichting Katholieke Universiteit Novel method for diagnosing lyme disease using a cellular immunological test
EP2622070B1 (de) 2010-09-30 2016-08-03 Novozymes, Inc. Polypeptidvarianten mit verstärkter zelluloseabbauender wirkung und dafür kodierende polynukleotide
EP2622068B1 (de) 2010-09-30 2016-07-20 Novozymes, Inc. Polypeptidvarianten mit verstärkter zelluloseabbauender wirkung und dafür kodierende polynukleotide
MX2013002586A (es) 2010-10-01 2013-03-21 Novozymes Inc Variantes de beta-glucosidasa y polinucleotidos que codifican las mismas.
RU2583293C2 (ru) 2010-10-01 2016-05-10 Новозимс А/С Полипептиды, обладающие эндопептидазной активностью, и кодирующие их полинуклеотиды
GB201016742D0 (en) 2010-10-05 2010-11-17 Health Prot Agency Clostridium difficile antigens
WO2012058293A1 (en) 2010-10-26 2012-05-03 Novozymes North America, Inc. Methods of saccharifying sugarcane trash
EP2632943A1 (de) 2010-10-29 2013-09-04 Novozymes A/S Polypeptide mit succinyl-coa:acetacetat-transferaseaktivität und dafür kodierende polynukleotide
MX2013004353A (es) 2010-10-29 2013-06-28 Novozymes Inc Produccion recombinante de n-propanol e isopropanol.
DK2635689T3 (en) 2010-11-02 2015-07-06 Novozymes Inc METHODS OF PREPARATION OF cellulosic material WITH A GH61-POLYPEPTIDE
EP2635594B1 (de) 2010-11-04 2017-01-11 Novozymes Inc. Polypeptide mit cellobiohydrolaseaktivität und dafür kodierende polynukleotide
DK2638154T3 (da) 2010-11-08 2017-01-02 Novozymes As Polypeptider med glucoamylaseaktivitet og polynukleotider, der koder for dem
EP2637515B1 (de) 2010-11-08 2017-09-06 Novozymes A/S Polypeptide mit glucoamylaseaktivität und dafür codierende polynukleotide
BR112013011442A2 (pt) 2010-11-12 2020-08-11 Novozymes A/S polipeptídeo isolado, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, método de produção do polipeptídeo, composição, uso do polipeptídeo ou da composição, métodos de redução do teor de componentes contendo fósforo em um óleo comestível, e para desengomagem de uma composição de óleo
BR112013009026A2 (pt) 2010-11-12 2016-07-12 Novozymes Inc polipeptídeo isolado, célula hospedeira recombinante, métodos para produzir um polipeptídeo, um mutante de uma célula precursora, uma proteína, e um produto de fermentação, para inibir a expressão de um polipeptídeo, para degradar ou converter um material celulósico, e método para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta, molécula de rna inibidora de filamento duplo, polinucleotídeo isolado, e, formulação de caldo integral ou composição de cultura de célula
WO2012068509A1 (en) 2010-11-18 2012-05-24 Novozymes, Inc. Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US8927235B2 (en) 2010-12-06 2015-01-06 Novozymes A/S Methods of hydrolyzing oligomers in hemicellulosic liquor
EP2465928A1 (de) 2010-12-16 2012-06-20 Academisch Medisch Centrum bij de Universiteit van Amsterdam Behandlung von Th17-vermittelten Krankheiten
WO2012103322A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
EP2668266B1 (de) 2011-01-26 2018-01-03 Novozymes A/S Polypeptide mit cellobiohydrolaseaktivität und dafür kodierende polynukleotide
US9157075B2 (en) 2011-01-26 2015-10-13 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
DK2668270T3 (en) 2011-01-26 2019-01-07 Novozymes Inc Polypeptides with cellobiohydrolase activity and polynucleotides encoding them
MX2013007720A (es) 2011-01-26 2013-08-09 Novozymes As Polipeptidos que tienen actividad celobiohidrolasa y polinucleotidos que codifican para los mismos.
DK2670853T3 (en) 2011-01-31 2017-08-28 Novozymes North America Inc Process for enzymatic refining of pretreated cellulosic material for sugars
JP2014511409A (ja) 2011-02-16 2014-05-15 ノボザイムス アクティーゼルスカブ 金属プロテアーゼを含む洗剤組成物
JP2014506945A (ja) 2011-02-16 2014-03-20 ノボザイムス アクティーゼルスカブ 金属プロテアーゼを含む洗剤組成物
US20140024103A1 (en) 2011-02-16 2014-01-23 Astrid Benie Detergent Compositions Comprising Metalloproteases
EP2678352B1 (de) 2011-02-23 2017-12-06 Novozymes, Inc. Polypeptide mit verstärkter zelluloseabbauender wirkung und dafür kodierende polynukleotide
WO2012118848A1 (en) 2011-02-28 2012-09-07 Novozymes, Inc. Microorganism for c4-dicarboxylic acid production
CN103608461B (zh) 2011-03-09 2016-08-03 诺维信公司 增加多肽的纤维素分解增强活性的方法
WO2012122477A1 (en) 2011-03-10 2012-09-13 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2012127002A1 (en) 2011-03-23 2012-09-27 Novozymes A/S Sweet-tasting polypeptide from gram-positive bacteria
WO2012127001A1 (en) 2011-03-23 2012-09-27 Novozymes A/S Methods for producing secreted polypeptides
US9879294B2 (en) 2011-03-25 2018-01-30 Novozymes A/S Methods for degrading or converting cellulosic material
WO2012135659A2 (en) 2011-03-31 2012-10-04 Novozymes A/S Methods for enhancing the degradation or conversion of cellulosic material
WO2012135719A1 (en) 2011-03-31 2012-10-04 Novozymes, Inc. Cellulose binding domain variants and polynucleotides encoding same
DK2702153T3 (en) 2011-04-28 2019-03-18 Novozymes Inc Polypeptides with endoglucanase activity and polynucleotides encoding them
DK2702162T3 (da) 2011-04-29 2020-05-18 Novozymes Inc Fremgangsmåder til forbedring af nedbrydningen eller omdannelsen af celluloseholdigt materiale
WO2012150319A1 (en) 2011-05-05 2012-11-08 Novozymes Biopharma Dk A/S Albumin variants
GB201108108D0 (en) 2011-05-16 2011-06-29 Syntaxin Ltd Therapeutic fusion proteins
EP2710132A1 (de) 2011-05-19 2014-03-26 Novozymes, Inc. Verfahren zur verstärkung des abbaus von zellulosestoffen mit chitinbindenden proteinen
EP2710133A1 (de) 2011-05-19 2014-03-26 Novozymes, Inc. Verfahren zur verstärkung des abbaus von zellulosestoffen mit chitinbindenden proteinen
EP2527432A1 (de) 2011-05-23 2012-11-28 Novozymes A/S Bidirektionaler Cytosin-Deaminase-codierender Selektionsmarker
EP2527448A1 (de) 2011-05-23 2012-11-28 Novozymes A/S Gleichzeitige standortspezifische Integrationen von mehreren Genkopien in faserige Pilze
CN103620029B (zh) 2011-06-24 2017-06-09 诺维信公司 具有蛋白酶活性的多肽和编码它们的多核苷酸
EP3421595B1 (de) 2011-06-30 2020-10-07 Novozymes A/S Alpha-amylase-varianten
EP2726500B1 (de) 2011-06-30 2019-03-20 Novozymes A/S Verfahren zum screening von alpha-amylasen
EP2540824A1 (de) 2011-06-30 2013-01-02 The Procter & Gamble Company Reinigungszusammensetzungen mit Amylasevariantenreferenz zu einem Sequenzprotokoll
MX337984B (es) 2011-07-06 2016-03-30 Novozymes As Variantes de alfa amilasa y polinucleotidos que codifican la misma.
WO2013004639A2 (en) 2011-07-07 2013-01-10 Novozymes A/S Enzymatic preparation of diols
JP6219277B2 (ja) 2011-07-08 2017-10-25 ディフェンシン セラピューティクス アンパルトセルスカブＤｅｆｅｎｓｉｎ Ｔｈｅｒａｐｅｕｔｉｃｓ Ａｐｓ 炎症性腸疾患の経口治療
CN103827298A (zh) 2011-07-15 2014-05-28 诺维信公司 脂肪酶变体及其编码多核苷酸
CN109022518A (zh) 2011-07-22 2018-12-18 诺维信北美公司 用于预处理纤维素材料和改进其水解的方法
BR112014002401B1 (pt) 2011-08-04 2021-08-03 Novozymes A/S Célula hospedeira transgênica de fungo filamentoso, métodos para produzir um polipeptídeo e uma proteína, e, construto de ácido nucleico ou um vetor de expressão
EP2739728B1 (de) 2011-08-04 2017-07-12 Novozymes A/S Polypeptide mit endoglucanase-aktivität und polynukleotide zu ihrer kodierung
WO2013021065A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021064A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP2742129B1 (de) 2011-08-10 2017-08-02 Novozymes A/S Polypeptide mit peroxygenase-aktivität und dafür kodierende polynukleotide
US9487761B2 (en) 2011-08-10 2016-11-08 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9506044B2 (en) 2011-08-10 2016-11-29 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021059A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021062A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP2744898A1 (de) 2011-08-15 2014-06-25 Novozymes A/S Polypeptide mit cellulase-aktivität und dafür kodierende polynukleotide
US20140295027A1 (en) 2011-08-19 2014-10-02 Novozymes A/S Polypeptides Having Protease Activity
BR112014003444A2 (pt) 2011-08-19 2017-03-14 Novozymes Inc célula hospedeira recombinante, e, método para produzir um ácido c4-dicarboxílico
WO2013026794A1 (en) 2011-08-19 2013-02-28 Novozymes Novel immunomodulatory peptide
CA2846690A1 (en) 2011-08-26 2013-03-07 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
GB201115214D0 (en) 2011-09-02 2011-10-19 Health Prot Agency Influenza virus antibody compositions
CN103930543B (zh) 2011-09-06 2020-11-27 诺维信公司 葡糖淀粉酶变体和编码它们的多核苷酸
CN103764905A (zh) 2011-09-09 2014-04-30 诺维信公司 改进纸张材料的特性
CA2847236A1 (en) 2011-09-09 2013-03-14 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP2756091A1 (de) 2011-09-13 2014-07-23 Novozymes North America, Inc. Verfahren zur hydrolyse und fermentierung von zellulosematerial
US20140308705A1 (en) 2011-09-20 2014-10-16 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
ES2628190T3 (es) 2011-09-22 2017-08-02 Novozymes A/S Polipéptidos con actividad de proteasa y polinucleótidos que codifican los mismos
IN2014CN02910A (de) 2011-09-23 2015-07-03 Novozymes As
EP2751261B1 (de) 2011-09-30 2018-08-29 Novozymes, Inc. Dehydrogenasevarianten und dafür kodierende polynukleotide
WO2013044867A1 (en) 2011-09-30 2013-04-04 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
US9353362B2 (en) 2011-10-11 2016-05-31 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
CA3253390A1 (en) 2011-10-17 2025-06-17 Novozymes A/S Variants of alpha-amylase and the polynucleotides encoding them
HUE039835T2 (hu) 2011-10-17 2019-02-28 Novozymes As Alfa-amiláz variánsok és az azokat kódoló polinukleotidok
US10308921B2 (en) 2011-10-31 2019-06-04 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2013064195A1 (en) 2011-11-04 2013-05-10 Enel Ingegneria E Ricerca S.P.A. A new heat-stable carbonic anhydrase and uses thereof
EP2794873A1 (de) 2011-11-08 2014-10-29 Novozymes A/S Verfahren zur herstellung von archeae-protease in hefe
HK1200842A1 (en) 2011-11-18 2015-08-14 Albumedix Ltd Proteins with improved half-life and other properties
EP2780449B1 (de) 2011-11-18 2018-04-11 Novozymes, Inc. Polypeptide mit beta-glucosidase-aktivität, beta-xylosidase-aktivität oder beta-glucosidase- und beta-xylosidase-aktivität sowie dafür kodierende polynukleotide
CN103958672A (zh) 2011-11-21 2014-07-30 诺维信股份有限公司 Gh61多肽变体以及编码所述变体的多核苷酸
DK2782998T3 (en) 2011-11-22 2018-04-16 Novozymes Inc POLYPEPTIDES WITH BETA-XYLOSIDASE ACTIVITY AND POLYNUCLEOTIDES CODING THEM
JP6105615B2 (ja) 2011-11-25 2017-03-29 ノボザイムス アクティーゼルスカブ リゾチーム活性を有するポリペプチドおよびそれをコードするポリヌクレオチド
US20140342433A1 (en) 2011-11-25 2014-11-20 Novozymes A/S Subtilase Variants and Polynucleotides Encoding Same
US9624481B2 (en) 2011-12-01 2017-04-18 Novozymes, Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
US9404093B2 (en) 2011-12-02 2016-08-02 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
US9169469B2 (en) 2011-12-02 2015-10-27 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013087027A1 (en) 2011-12-16 2013-06-20 Novozymes, Inc. Polypeptides having laccase activity and polynucleotides encoding same
WO2013091547A1 (en) 2011-12-19 2013-06-27 Novozymes, Inc. Polypeptides having catalase activity and polynucleotides encoding same
MX2014007446A (es) 2011-12-20 2014-08-01 Novozymes As Variantes de subtilasa y polinucleotidos que las codifican.
EP2607468A1 (de) 2011-12-20 2013-06-26 Henkel AG & Co. KGaA Reinigungsmittelzusammensetzungen mit Subtilasevarianten
DK2794869T3 (en) 2011-12-20 2018-01-02 Novozymes Inc CELLOBIO HYDROLASE VARIABLES AND POLYNUCLEOTIDES CODING THEM
ES2667318T3 (es) 2011-12-28 2018-05-10 Novozymes A/S Polipéptidos con actividad de proteasa
US9801398B2 (en) 2012-01-26 2017-10-31 Novozymes A/S Use of polypeptides having protease activity in animal feed and detergents
DK2623586T3 (da) 2012-02-03 2017-11-13 Procter & Gamble Sammensætninger og fremgangsmåder til overfladebehandling med lipaser
EP4570895A3 (de) 2012-02-03 2026-01-14 Novozymes A/S Lipasevarianten und polynukleotide zu deren codierung
MX350713B (es) 2012-02-17 2017-09-14 Novozymes As Variantes de subtilisina y polinucleotidos que las codifican.
EP2628785B1 (de) 2012-02-17 2016-05-18 Henkel AG & Co. KGaA Reinigungsmittelzusammensetzungen mit Subtilasevarianten
PT2817325T (pt) 2012-02-20 2019-10-01 Novozymes As Polipéptidos que têm atividade da endoglucanase e polinucleotídeos codificando mesmos
EP3330283A3 (de) 2012-03-16 2018-07-11 Albumedix A/S Albuminvarianten
US9458478B2 (en) 2012-03-31 2016-10-04 Novozymes A/S Epoxidation using peroxygenase
EP2834353B1 (de) 2012-04-02 2017-07-19 Novozymes A/S Lipasevarianten und polynukleotide zu deren codierung
US9446102B2 (en) 2012-04-23 2016-09-20 Novozymes A/S Polypeptides having alpha-glucuronidase activity and polynucleotides encoding same
EP2841570B1 (de) 2012-04-23 2017-12-20 Novozymes A/S Polypeptide mit glucuronyl-esteraseaktivität und polynukleotide zur codierung davon
CA2870773A1 (en) 2012-04-25 2013-10-31 Novozymes A/S Method of baking
CN104245926B (zh) 2012-04-27 2021-05-07 诺维信股份有限公司 Gh61多肽变体以及编码其的多核苷酸
CN113201519A (zh) 2012-05-07 2021-08-03 诺维信公司 具有黄原胶降解活性的多肽以及编码其的核苷酸
EP2850180A1 (de) 2012-05-18 2015-03-25 Novozymes A/S Bakterielle mutanten mit verbesserter transformationseffizienz
EP2855670A2 (de) 2012-05-31 2015-04-08 Novozymes A/S Polypeptide mit organophosphor-hydrolase-aktivität
WO2013178699A1 (en) 2012-05-31 2013-12-05 Novozymes A/S Isopropanol production by bacterial hosts
EP2861749A1 (de) 2012-06-19 2015-04-22 Novozymes Bioag A/S Enzymatische reduktion von hydroperoxiden
MX364390B (es) 2012-06-20 2019-04-25 Novozymes As Uso de polipeptidos que tienen actividad proteasa en alimentos para animales y detergentes.
CN104471048B (zh) 2012-07-12 2018-11-16 诺维信公司 具有脂肪酶活性的多肽及编码它的多核苷酸
EP2875179B1 (de) 2012-07-18 2018-02-21 Novozymes A/S Verfahren zur behandlung von polyestertextilien
US20150152452A1 (en) 2012-07-20 2015-06-04 Novozymes A/S Enzymatic Oxidation of 5-Hydroxymethylfurfural and Derivatives Thereof
CN104583394B (zh) 2012-08-16 2019-06-07 诺维信公司 用内切葡聚糖酶处理纺织品的方法
US9828595B2 (en) 2012-08-17 2017-11-28 Novozymes A/S Thermostable asparaginase variants and polynucleotides encoding same
US9315791B2 (en) 2012-08-22 2016-04-19 Novozymes A/S Metalloproteases from alicyclobacillus
MX2015002211A (es) 2012-08-22 2015-05-08 Novozymes As Metaloproteasa de exiguobacterium.
WO2014029820A1 (en) 2012-08-22 2014-02-27 Novozymes A/S Detergent compositions comprising metalloproteases
AU2013311668B2 (en) 2012-09-05 2019-02-28 Novozymes A/S Polypeptides having protease activity
BR112015005884A2 (pt) 2012-09-19 2017-08-08 Novozymes Inc E Novozymes As processos para degradação de um material celulósico, para produção de um produto da fermentação, e de fermentação de um material celulósico, composição, e, formulação de caldo inteiro ou composição de cultura de células
WO2014052630A1 (en) 2012-09-27 2014-04-03 Novozymes, Inc. Bacterial mutants with improved transformation efficiency
EP2904099B1 (de) 2012-10-05 2018-12-19 Novozymes A/S Verhindern von bakterienadhäsion
EP3586610B1 (de) 2012-10-08 2024-09-25 Novozymes A/S Polypeptide mit verstärkter celluloseabbauender wirkung und polynukleotide zur codierung davon
EP2906685B1 (de) 2012-10-12 2018-08-15 Novozymes A/S Polypeptide mit peroxygenaseaktivität
EP2906689B1 (de) 2012-10-12 2018-12-12 Novozymes A/S Polypeptide mit peroxygenaseaktivität
US9453207B2 (en) 2012-10-12 2016-09-27 Novozymes A/S Polypeptides having peroxygenase activity
EP2906686B1 (de) 2012-10-12 2018-08-29 Novozymes A/S Polypeptide mit peroxygenaseaktivität
CN104718287B (zh) 2012-10-12 2018-02-06 诺维信公司 具有过氧合酶活性的多肽
WO2014056916A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
US9404094B2 (en) 2012-10-12 2016-08-02 Novozymes A/S Polypeptides having peroxygenase activity
WO2014066141A2 (en) 2012-10-24 2014-05-01 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2014068010A1 (en) 2012-10-31 2014-05-08 Novozymes A/S Isopropanol production by bacterial hosts
CA2890766A1 (en) 2012-11-08 2014-05-15 Novozymes Biopharma Dk A/S Albumin variants
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
EP2925873B1 (de) 2012-11-30 2017-07-12 Novozymes, Inc. Herstellung von 3-hydroxypropionsäure mittels rekombinanter hefen
TR201910918T4 (tr) 2012-12-07 2019-08-21 Novozymes As Bakterilerin yapışmasının önlenmesi.
EP2740840A1 (de) 2012-12-07 2014-06-11 Novozymes A/S Verbesserter Ablass von Papiermasse
US20150307871A1 (en) 2012-12-07 2015-10-29 Novozymes A/S Method for generating site-specific mutations in filamentous fungi
US20150368627A1 (en) 2012-12-11 2015-12-24 Novozymes A/S Polypeptides Having Phospholipase C Activity and Polynucleotides Encoding Same
WO2014090940A1 (en) 2012-12-14 2014-06-19 Novozymes A/S Removal of skin-derived body soils
US9765373B2 (en) 2012-12-14 2017-09-19 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
ES2772032T3 (es) 2012-12-17 2020-07-07 Novozymes As Alfa-amilasas y polinucleótidos que las codifican
WO2014099798A1 (en) 2012-12-19 2014-06-26 Novozymes A/S Polypeptides having cellulolytic enhancinc activity and polynucleotides encoding same
US9551042B2 (en) 2012-12-21 2017-01-24 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
EP2938628A4 (de) 2012-12-24 2016-10-19 Novozymes As Polypeptide mit endoglucanaseaktivität und polynukleotide zur codierung davon
EP3321360A3 (de) 2013-01-03 2018-06-06 Novozymes A/S Alpha-amylase-varianten und polynukleotide zur codierung davon
WO2014122109A1 (en) 2013-02-05 2014-08-14 Novozymes A/S Enzymatic preparation of indigo dyes and intermediates
MX2015010078A (es) 2013-02-06 2016-01-25 Novozymes As Uso de polipeptidos con actividad proteasa en alimentos para animales.
CN105164254B (zh) 2013-03-08 2019-06-28 诺维信公司 纤维二糖水解酶变体和编码它们的多核苷酸
WO2014142646A1 (en) 2013-03-13 2014-09-18 Stichting Katholieke Universiteit Q-fever diagnostic
US9631164B2 (en) 2013-03-21 2017-04-25 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
EP3533866A1 (de) 2013-03-21 2019-09-04 Novozymes A/S Polypeptide mit phospholipase-a-activität und polynucleotide zu deren codierung
WO2014170218A1 (en) 2013-04-18 2014-10-23 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
WO2014173980A2 (en) 2013-04-23 2014-10-30 Novozymes A/S Liquid automatic dish washing detergent compositions
WO2014177541A2 (en) 2013-04-30 2014-11-06 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
EP3372680B1 (de) 2013-04-30 2020-11-11 Novozymes A/S Glycoamylasevarianten und polynukleotide zur codierung davon
JP2016524697A (ja) 2013-05-02 2016-08-18 スティッチング カソリーケ ウニベルシテイトＳｔｉｃｈｔｉｎｇ Ｋａｔｈｏｌｉｅｋｅ Ｕｎｉｖｅｒｓｉｔｅｉｔ 個人化医療
CN105164244B (zh) 2013-05-03 2019-08-20 诺维信公司 洗涤剂酶的微囊化
US9556465B2 (en) 2013-05-10 2017-01-31 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
MX392247B (es) 2013-05-14 2025-03-24 Novozymes As Composiciones detergentes.
US20160083703A1 (en) 2013-05-17 2016-03-24 Novozymes A/S Polypeptides having alpha amylase activity
CN114634921B (zh) 2013-06-06 2024-09-10 诺维信公司 α-淀粉酶变体以及对其进行编码的多核苷酸
WO2014202089A2 (en) 2013-06-18 2014-12-24 Roskilde Universitet Variants of anti-freeze polypeptides
US20160122772A1 (en) 2013-06-21 2016-05-05 Novozymes A/S Production of Polypeptides Without Secretion Signal in Bacillus
WO2014207224A1 (en) 2013-06-27 2014-12-31 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2014207227A1 (en) 2013-06-27 2014-12-31 Novozymes A/S Subtilase variants and polynucleotides encoding same
JP2016523098A (ja) 2013-07-04 2016-08-08 ノボザイムス アクティーゼルスカブ 再付着防止効果を有するポリペプチドおよびそれをコードするポリヌクレオチド
WO2015004102A1 (en) 2013-07-09 2015-01-15 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
DK3022300T3 (en) 2013-07-17 2018-10-22 Novozymes As : Pullulan chimeras and polynucleotides encoding them
EP3027747B1 (de) 2013-07-29 2018-02-07 Novozymes A/S Proteasevarianten und polynukleotide zur codierung davon
CN105358686A (zh) 2013-07-29 2016-02-24 诺维信公司 蛋白酶变体以及对其进行编码的多核苷酸
EP2832853A1 (de) 2013-07-29 2015-02-04 Henkel AG&Co. KGAA Waschmittelzusammensetzung mit Proteasevarianten
US9845484B2 (en) 2013-07-31 2017-12-19 Novozymes A/S 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase
US10010094B2 (en) 2013-08-15 2018-07-03 Novozymes A/S Polypeptides having beta-1,3-galactanase activity and polynucleotides encoding same
WO2015049370A1 (en) 2013-10-03 2015-04-09 Novozymes A/S Detergent composition and use of detergent composition
WO2015059133A1 (en) 2013-10-22 2015-04-30 Novozymes A/S Cellobiose dehydrogenase variants and polynucleotides encoding same
EP2876156A1 (de) 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives Neue Enzyme und Verfahren zur Herstellung von hydroxyliertem L-Lysin oder L-Ornithin und Analoga davon
WO2015079064A2 (en) 2013-11-29 2015-06-04 Novozymes A/S Peroxygenase variants
CN122012456A (zh) 2013-12-11 2026-05-12 诺维信公司 角质酶变体以及对其进行编码的多核苷酸
EP2886656A1 (de) 2013-12-18 2015-06-24 Commissariat A L'energie Atomique Et Aux Energies Alternatives Neues Enzym und Verfahren zur Herstellung von 4-hydroxylbenzylalkohol und Derivaten davon
EP3453757B1 (de) 2013-12-20 2020-06-17 Novozymes A/S Polypeptide mit proteaseaktivität und polynukleotide, die für diese kodieren
EP3097192B1 (de) 2014-01-22 2018-07-25 Novozymes A/S Pulluonasevarianten und polynukleotide zur codierung davon
EP3097112B1 (de) 2014-01-22 2020-05-13 Novozymes A/S Polypeptide mit lipaseaktivität und polynukleotide zur codierung davon
US10155935B2 (en) 2014-03-12 2018-12-18 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
WO2015143144A1 (en) 2014-03-19 2015-09-24 Novozymes A/S Method for enhancing activity of an x143 polypeptide
EP3119862B1 (de) 2014-03-19 2022-09-07 Novozymes A/S Polypeptide mit phospholipase-c-aktivität und dafür codierende polynukleotide
WO2015150457A1 (en) 2014-04-01 2015-10-08 Novozymes A/S Polypeptides having alpha amylase activity
WO2015157656A1 (en) 2014-04-10 2015-10-15 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
CN106164236B (zh) 2014-04-11 2021-02-02 诺维信公司 洗涤剂组合物
US10030215B2 (en) 2014-04-15 2018-07-24 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
BR112016023769A2 (pt) 2014-04-17 2017-10-17 Boehringer Ingelheim Rcv Gmbh célula hospedeira recombinante para a expressão de proteínas de interesse
US10865416B2 (en) 2014-04-17 2020-12-15 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell engineered to overexpress helper proteins
CN106459934A (zh) 2014-05-15 2017-02-22 诺维信公司 包括具有磷脂酶c活性的多肽的组合物及其应用
EP3149178B1 (de) 2014-05-27 2020-07-15 Novozymes A/S Lipasevarianten und polynukleotide zur codierung davon
CA2950273C (en) 2014-05-30 2022-06-21 Novozymes A/S Variants of gh family 11 xylanase and polynucleotides encoding same
EP2952584A1 (de) 2014-06-04 2015-12-09 Boehringer Ingelheim RCV GmbH & Co KG Verbesserte Proteinherstellung
US20170121695A1 (en) 2014-06-12 2017-05-04 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
ES2712402T3 (es) 2014-06-25 2019-05-13 Novozymes As Variantes de xilanasa y polinucleótidos que las codifican
WO2016001319A1 (en) 2014-07-03 2016-01-07 Novozymes A/S Improved stabilization of non-protease enzyme
EP3739029A1 (de) 2014-07-04 2020-11-18 Novozymes A/S Subtilasevarianten und polynukleotide zur codierung davon
EP3327122B1 (de) 2014-07-04 2021-02-17 Novozymes A/S Subtilasevarianten und polynukleotide zur codierung davon
US20170267980A1 (en) 2014-08-20 2017-09-21 Novozymes A/S Xyloglucan Endotransglycosylase variants and Polynucleotides Encoding Same
EP3189137A1 (de) 2014-09-05 2017-07-12 Novozymes A/S Kohlenhydratbindende modulvarianten und polynukleotide zur codierung davon
WO2016062875A2 (en) 2014-10-23 2016-04-28 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
US10619145B2 (en) 2014-11-04 2020-04-14 Novozymes A/S Polypeptides having serine protease activity and polynucleotides encoding same and their application in animal feed
WO2016073610A1 (en) 2014-11-07 2016-05-12 Novozymes A/S Xylanase based bleach boosting
WO2016079305A1 (en) 2014-11-20 2016-05-26 Novozymes A/S Alicyclobacillus variants and polynucleotides encoding same
WO2016087327A1 (en) 2014-12-01 2016-06-09 Novozymes A/S Polypeptides having pullulanase activity comprising the x25, x45 and cbm41 domains
WO2016090059A1 (en) 2014-12-02 2016-06-09 Novozymes A/S Laccase variants and polynucleotides encoding same
EP3227425B1 (de) 2014-12-04 2025-02-12 Novozymes A/S Flüssige reinigungszusammensetzungen mit proteasevarianten
MX2017006695A (es) 2014-12-04 2017-08-21 Novozymes As Variantes de subtilasa y polinucleotidos que las codifican.
EP3227442B1 (de) 2014-12-05 2022-02-16 Novozymes A/S Lipasevarianten und polynukleotide zur codierung davon
US20180000076A1 (en) 2014-12-16 2018-01-04 Novozymes A/S Polypeptides Having N-Acetyl Glucosamine Oxidase Activity
MX383142B (es) 2014-12-19 2025-03-13 Novozymes As Composiciones que comprenden polipéptidos que tienen actividad xilanasa y polipéptidos que tienen actividad arabinofuranosidasa.
WO2016100910A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
EP3741849A3 (de) 2014-12-19 2021-03-17 Novozymes A/S Proteasevarianten und polynukleotide zur codierung davon
WO2016097352A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Protease variants and polynucleotides encoding same
FI3739045T3 (fi) 2015-02-24 2024-11-13 Novozymes As Sellobiohydrolaasivariantteja ja niitä koodittavia polynukleotideja
EP3262180A1 (de) 2015-02-25 2018-01-03 Danisco US Inc. Alpha-glucosidase, zusammensetzungen und verfahren
EP3262161B1 (de) 2015-02-27 2021-06-30 Novozymes A/S Mutante wirtszellen zur herstellung von 3-hydroxypropionsäure
BR112017020007B1 (pt) 2015-03-19 2022-09-20 Novozymes A/S Método para preparar um mosto com um nível aumentado de nitrogênio livre aminado (fan) e uso de uma protease
WO2016162556A1 (en) 2015-04-10 2016-10-13 Novozymes A/S Laundry method, use of dnase and detergent composition
CN107636134A (zh) 2015-04-10 2018-01-26 诺维信公司 洗涤剂组合物
US10125198B2 (en) 2015-04-17 2018-11-13 Distributed Bio, Inc. Method for mass humanization of non-human antibodies
US11685773B2 (en) 2015-04-30 2023-06-27 Abcheck S.R.O. Method for mass humanization of rabbit antibodies
JP7175612B2 (ja) 2015-05-08 2022-11-21 ノボザイムス アクティーゼルスカブ アルファ－アミラーゼ多様体およびこの多様体をコードするポリヌクレオチド
US20180142224A1 (en) 2015-05-08 2018-05-24 Novozymes A/S Alpha-amylase variants having improved performance and stability
AR105416A1 (es) 2015-05-08 2017-10-04 Novozymes As VARIANTES DE a-AMILASA Y POLINUCLEÓTIDOS QUE LAS CODIFICAN
CN107532154B (zh) 2015-05-27 2022-09-27 国投生物科技投资有限公司 具有纤维二糖水解酶活性的多肽以及对其进行编码的多核苷酸
WO2016196202A1 (en) 2015-05-29 2016-12-08 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
WO2016193420A1 (en) 2015-06-04 2016-12-08 Novozymes A/S Use of m4 metalloprotease in wort production
EP3310908B1 (de) 2015-06-16 2020-08-05 Novozymes A/S Polypeptide mit lipaseaktivität und polynukleotide zur codierung davon
CN121406620A (zh) 2015-06-18 2026-01-27 诺维信公司 枯草杆菌酶变体以及编码它们的多核苷酸
US10676727B2 (en) 2015-06-18 2020-06-09 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
WO2016207373A1 (en) 2015-06-26 2016-12-29 Novozymes A/S Polypeptides having peroxygenase activity
AU2016282355B2 (en) 2015-06-26 2020-04-09 Novozymes A/S Method for producing a coffee extract
EP3313990A4 (de) 2015-06-26 2019-01-23 Novozymes A/S Bio-endbearbeitungssystem
CA2987160C (en) 2015-07-01 2022-12-13 Novozymes A/S Methods of reducing odor
AU2016286612B2 (en) 2015-07-02 2021-01-28 Novozymes A/S Animal feed compositions and uses thereof
CN114292829A (zh) 2015-07-06 2022-04-08 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
CN108138153A (zh) 2015-07-24 2018-06-08 诺维信股份有限公司 具有阿拉伯呋喃糖苷酶活性的多肽以及编码它们的多核苷酸
WO2017019491A1 (en) 2015-07-24 2017-02-02 Novozymes Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
BR112018003179A2 (pt) 2015-08-20 2018-09-25 Albumedix As conjugados e variantes de albumina
WO2017035270A1 (en) 2015-08-24 2017-03-02 Novozymes A/S Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid
MX2018002183A (es) 2015-08-27 2018-05-28 Harvard College Composiciones y metodos para tratamiento del dolor.
US10479984B2 (en) 2015-09-22 2019-11-19 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
GB201517450D0 (en) 2015-10-02 2015-11-18 Ipsen Biopharm Ltd Method
WO2017060662A1 (en) 2015-10-07 2017-04-13 The Secretary Of State For Health Method for providing a control for use in a screen for pathogenic virus
WO2017060475A2 (en) 2015-10-07 2017-04-13 Novozymes A/S Polypeptides
US20180171318A1 (en) 2015-10-14 2018-06-21 Novozymes A/S Polypeptides Having Protease Activity and Polynucleotides Encoding Same
EP3362574B1 (de) 2015-10-14 2021-07-07 Novozymes A/S Glycoamylasevarianten und polynukleotide zur codierung davon
US10675589B2 (en) 2015-10-14 2020-06-09 Novozymes A/S Cleaning of water filtration membranes
CN108291212A (zh) 2015-10-14 2018-07-17 诺维信公司 多肽变体
WO2017070219A1 (en) 2015-10-20 2017-04-27 Novozymes A/S Lytic polysaccharide monooxygenase (lpmo) variants and polynucleotides encoding same
ES3069936T3 (en) 2015-10-28 2026-06-11 Novozymes As Detergent composition comprising amylase and protease variants
US11001821B2 (en) 2015-11-24 2021-05-11 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
EP3384019B1 (de) 2015-12-01 2020-06-24 Novozymes A/S Verfahren zur herstellung von lipasen
US10035995B2 (en) 2015-12-07 2018-07-31 Eastman Chemical Company CALB variants
ES2932192T3 (es) 2015-12-07 2023-01-16 Henkel Ag & Co Kgaa Composiciones para el lavado de vajilla que comprenden polipéptidos que tienen actividad beta-glucanasa y sus usos
JP7146637B2 (ja) 2015-12-22 2022-10-04 アルブミディクス リミティド 改善されたタンパク質発現株
WO2017112847A1 (en) 2015-12-22 2017-06-29 Albumedix A/S Improved protein expression strains
CN108603185B (zh) 2015-12-30 2022-05-17 诺维信公司 酶变体以及编码它们的多核苷酸
US20210171927A1 (en) 2016-01-29 2021-06-10 Novozymes A/S Beta-glucanase variants and polynucleotides encoding same
US11685911B2 (en) 2016-02-16 2023-06-27 Monaghan Mushroom S Group Fungal polypeptides having lysozyme activity
BR112018067371A2 (pt) 2016-03-02 2019-01-15 Novozymes As variante de celobio-hidrolase, composição de enzimas, formulação de caldo inteiro ou composição de cultura de células, polinucleotídeo, célula hospedeira recombinante, planta, parte de planta ou célula de planta transgênica, métodos para produção e para obtenção de uma variante de celobio-hidrolase, planta trangênica, e, processos para degradação de um material celulósico, para produção de um produto de fermentação e para fermentação de um material celulósico
CN109072209A (zh) 2016-03-24 2018-12-21 诺维信公司 纤维二糖水解酶变体和编码其的多核苷酸
PL3448409T3 (pl) 2016-04-29 2026-02-23 Defensin Therapeutics Aps Leczenie chorób wątroby, dróg żółciowych i trzustki defensynami
US10626354B2 (en) 2016-04-29 2020-04-21 Novozymes A/S Detergent compositions and uses thereof
US20240218340A1 (en) 2016-05-03 2024-07-04 Novozymes A/S Enzyme Variants and Polynucleotides Encoding Same
JP6985295B2 (ja) 2016-05-09 2021-12-22 ノボザイムス アクティーゼルスカブ 向上した性能を有する変異体ポリペプチドおよびその使用
EP3246401A1 (de) 2016-05-20 2017-11-22 Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives Neue fettsäuredecarboxylase und deren verwendungen
ES3014057T3 (en) 2016-05-24 2025-04-16 Novozymes As Gastric stable polypeptides having alpha-galactosidase activity and polynucleotides encoding same
AU2017270269A1 (en) 2016-05-24 2018-11-15 Novozymes A/S Compositions comprising polypeptides having galactanase activity and polypeptides having beta-galactosidase activity
CN109312321A (zh) 2016-05-24 2019-02-05 诺维信公司 包含具有半乳聚糖酶活性的多肽和具有β-半乳糖苷酶活性的多肽的组合物
AU2017269498A1 (en) 2016-05-24 2018-11-08 Novozymes A/S Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
WO2017205535A1 (en) 2016-05-27 2017-11-30 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2017210188A1 (en) 2016-05-31 2017-12-07 Novozymes A/S Stabilized liquid peroxide compositions
WO2017207762A1 (en) 2016-06-03 2017-12-07 Novozymes A/S Subtilase variants and polynucleotides encoding same
WO2017211803A1 (en) 2016-06-07 2017-12-14 Novozymes A/S Co-expression of heterologous polypeptides to increase yield
CN117721095A (zh) 2016-06-30 2024-03-19 诺维信公司 脂肪酶变体及包含表面活性剂和脂肪酶变体的组合物
WO2018002379A2 (en) 2016-07-01 2018-01-04 Novozymes A/S Enzymatic preparation of indigo dyes and in situ dyeing process
WO2018002261A1 (en) 2016-07-01 2018-01-04 Novozymes A/S Detergent compositions
CN109715794A (zh) 2016-07-05 2019-05-03 诺维信公司 果胶裂解酶变体以及编码它们的多核苷酸
MX2019000139A (es) 2016-07-08 2019-06-10 Novozymes As Polipeptidos que tienen actividad xilanasa y polinucleotidos que los codifican.
RU2752204C2 (ru) 2016-07-08 2021-07-23 Новозимс А/С Варианты ксиланазы и кодирующие их полинуклеотиды
WO2018007573A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Detergent compositions with galactanase
CN109415708A (zh) 2016-07-13 2019-03-01 宝洁公司 食物芽孢杆菌脱氧核糖核酸酶变体及其用途
CN109790525A (zh) 2016-07-18 2019-05-21 诺维信公司 脂肪酶变体、编码其的多核苷酸及其用途
WO2018017792A1 (en) 2016-07-20 2018-01-25 Novozymes A/S Heat-stable metagenomic carbonic anhydrases and their use
CN109661465A (zh) 2016-07-21 2019-04-19 诺维信公司 丝氨酸蛋白酶变体以及对其进行编码的多核苷酸
FI3487996T3 (fi) 2016-07-21 2024-07-10 Novozymes As Seriiniproteaasivariantteja ja niitä koodittavia polynukleotideja
WO2018015444A1 (en) 2016-07-22 2018-01-25 Novozymes A/S Crispr-cas9 genome editing with multiple guide rnas in filamentous fungi
WO2018026868A1 (en) 2016-08-01 2018-02-08 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
EP3504330A1 (de) 2016-08-24 2019-07-03 Novozymes A/S Gh9-endoglucanase-varianten und polynukleotide zur codierung davon
WO2018037064A1 (en) 2016-08-24 2018-03-01 Henkel Ag & Co. Kgaa Detergent compositions comprising xanthan lyase variants i
AU2017317564B2 (en) 2016-08-24 2021-09-30 Henkel Ag & Co. Kgaa Detergent composition comprising GH9 endoglucanase variants I
US11512300B2 (en) 2016-08-24 2022-11-29 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
US20190284647A1 (en) 2016-09-29 2019-09-19 Novozymes A/S Spore Containing Granule
US20210284933A1 (en) 2016-10-25 2021-09-16 Novozymes A/S Detergent compositions
WO2018085370A1 (en) 2016-11-02 2018-05-11 Novozymes A/S Processes for reducing production of primeverose during enzymatic saccharification of lignocellulosic material
JP7645607B2 (ja) 2016-11-16 2025-03-14 ヤンセン バイオテツク，インコーポレーテツド 抗ｉｌ２３特異的抗体で乾癬を治療する方法
EP3541954A1 (de) 2016-11-21 2019-09-25 Novozymes A/S Durch hefezellenextrakt unterstützte konstruktion von dna-molekülen
CN110072997A (zh) 2016-11-23 2019-07-30 诺维信公司 具有蛋白酶活性的多肽和编码其的多核苷酸
US20210292723A1 (en) 2016-11-29 2021-09-23 Novozymes A/S Alpha-Amylase Variants and Polynucleotides Encoding Same
MX2019006122A (es) 2016-11-30 2019-08-14 Novozymes As Metodo de hornear.
WO2018106792A1 (en) 2016-12-06 2018-06-14 Novozymes A/S Improved processes for production of ethanol from xylose-containing cellulosic substrates using engineered yeast strains
CA3045079A1 (en) 2016-12-13 2018-06-21 Defensin Therapeutics Aps Methods for treating inflammatory conditions of the lungs
CN110114465A (zh) 2016-12-20 2019-08-09 诺维信公司 用于戊糖发酵的重组酵母菌株
AU2017380488B2 (en) 2016-12-21 2023-09-14 Novozymes A/S Polypeptides having lysozyme activity, polynucleotides encoding same and uses and compositions thereof
CN110234351A (zh) 2017-01-30 2019-09-13 詹森生物科技公司 用于治疗活动性银屑病关节炎的抗tnf抗体、组合物和方法
EP3577219B1 (de) 2017-02-01 2023-08-23 Novozymes A/S Alpha-amylase varianten
RU2019123965A (ru) 2017-02-01 2021-02-01 Дзе Проктер Энд Гэмбл Компани Очищающие композиции, содержащие варианты амилазы
KR20240038148A (ko) 2017-02-07 2024-03-22 얀센 바이오테크 인코포레이티드 활성 강직성 척추염의 치료를 위한 항-tnf 항체, 조성물, 및 방법
MX2019009551A (es) 2017-02-20 2020-01-30 Novozymes As Enzima lipolitica para usarse en horneado.
CA3055530A1 (en) 2017-03-07 2018-09-13 Danisco Us Inc. Thermostable glucoamylase and methods of use, thereof
US11479798B2 (en) 2017-03-29 2022-10-25 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell with altered membrane lipid composition
CN110651040A (zh) 2017-03-31 2020-01-03 诺维信公司 具有dna酶活性的多肽
EP3601549B1 (de) 2017-03-31 2026-07-01 Novozymes A/S Polypeptide mit dnase-aktivität
CN110651041A (zh) 2017-03-31 2020-01-03 诺维信公司 具有dna酶活性的多肽
US11149233B2 (en) 2017-03-31 2021-10-19 Novozymes A/S Polypeptides having RNase activity
CN110651029B (zh) 2017-04-04 2022-02-15 诺维信公司 糖基水解酶
WO2018185152A1 (en) 2017-04-04 2018-10-11 Novozymes A/S Polypeptide compositions and uses thereof
EP3607039A1 (de) 2017-04-04 2020-02-12 Novozymes A/S Polypeptide
BR112019021223A2 (pt) 2017-04-11 2020-04-28 Novozymes A/S variante de glucoamilase, métodos para aumentar a atividade de hidrólise de amido em bruto de uma glucoamilase e para produzir uma variante de glucoamilase, composição, uso de uma variante de glucoamilase, processos para produzir um produto de fermentação e para produzir um produto de xarope, polinucleotídeo codificando a variante de glucoamilase, construto de ácido nucleico, vetor de expressão, e, célula hospedeira.
WO2018202846A1 (en) 2017-05-05 2018-11-08 Novozymes A/S Compositions comprising lipase and sulfite
CA3058095A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2018206535A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Carbohydrate-binding domain and polynucleotides encoding the same
EP3622064B1 (de) 2017-05-08 2025-05-14 Novozymes A/S Mannanase-varianten und dafür codierende polynukleotide
EP3401385A1 (de) 2017-05-08 2018-11-14 Henkel AG & Co. KGaA Tensidzusammensetzungen enthaltend polypeptide enthaltend eine carbohydrate binding domain
WO2018220116A1 (en) 2017-05-31 2018-12-06 Novozymes A/S Xylose fermenting yeast strains and processes thereof for ethanol production
AU2018275794A1 (en) 2017-06-02 2019-12-05 Novozymes A/S Improved yeast for ethanol production
WO2018224544A1 (en) 2017-06-08 2018-12-13 Novozymes A/S Compositions comprising polypeptides having cellulase activity and amylase activity, and uses thereof in cleaning and detergent compositions
WO2018224035A1 (en) 2017-06-09 2018-12-13 Novozymes A/S Polypeptide, use and method for hydrolysing protein
EP4026908A1 (de) 2017-06-20 2022-07-13 Albumedix Ltd Verbesserte proteinexpressionsstämme
EP3642339B1 (de) 2017-06-22 2025-09-10 Novozymes A/S Xylanasevarianten und polynukleotide zur codierung davon
DK3645555T3 (da) 2017-06-28 2022-03-07 Novozymes As Polypeptider med trehalaseaktivitet og polynukleotider, der koder for disse
US20200181542A1 (en) 2017-06-30 2020-06-11 Novozymes A/S Enzyme Slurry Composition
KR102683528B1 (ko) 2017-07-24 2024-07-10 노보자임스 에이/에스 습식 제분에서의 gh5 및 gh30
CA3070281A1 (en) 2017-08-08 2019-02-14 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
US20210130744A1 (en) 2017-08-24 2021-05-06 Henkel Ag & Co. Kgaa Detergent composition comprising xanthan lyase variants ii
EP3673056A1 (de) 2017-08-24 2020-07-01 Henkel AG & Co. KGaA Waschmittelzusammensetzung mit gh9-endoglucanasevarianten ii
WO2019038058A1 (en) 2017-08-24 2019-02-28 Novozymes A/S GH9 ENDOGLUCANASE VARIANTS AND POLYNUCLEOTIDES ENCODING SUCH VARIANTS
CN111344404A (zh) 2017-08-24 2020-06-26 诺维信公司 黄原胶裂解酶变体以及编码其的多核苷酸
AU2018322748B2 (en) 2017-08-29 2024-05-02 Novozymes A/S Baker's yeast expressing anti-staling/freshness amylases
HUE072278T2 (hu) 2017-08-31 2025-11-28 Novozymes As D-pszikóz-3-epimeráz aktivitású polipeptidek és ezeket kódoló polinukleotidok
WO2019046703A1 (en) 2017-09-01 2019-03-07 Novozymes A/S METHODS OF ENHANCING GENOME EDITION IN FUNGI
US20200196633A1 (en) 2017-09-01 2020-06-25 Novozymes A/S Animal Feed Additives Comprising Polypeptide Having Protease Activity and Uses Thereof
CN111050566A (zh) 2017-09-01 2020-04-21 诺维信公司 包含具有蛋白酶活性的多肽的动物饲料添加剂及其用途
WO2019047199A1 (en) 2017-09-11 2019-03-14 Danisco Us Inc. GLUCOAMYLASE AND METHODS OF USE THEREOF
TW201922780A (zh) 2017-09-25 2019-06-16 美商健生生物科技公司 以抗ｉｌ１２／ｉｌ２３抗體治療狼瘡之安全且有效之方法
MX2020003779A (es) 2017-09-27 2020-08-03 Procter & Gamble Composiciones detergentes que comprenden lipasas.
CN118910005A (zh) 2017-09-27 2024-11-08 诺维信公司 脂肪酶变体和包含此类脂肪酶变体的微囊组合物
US11746310B2 (en) 2017-10-02 2023-09-05 Novozymes A/S Polypeptides having mannanase activity and polynucleotides encoding same
CN111373036A (zh) 2017-10-02 2020-07-03 诺维信公司 具有甘露聚糖酶活性的多肽和编码它们的多核苷酸
WO2019070883A1 (en) 2017-10-04 2019-04-11 Novozymes A/S POLYPEPTIDES WITH PROTEASE ACTIVITY AND POLYNUCLEOTIDES ENCODING SAME
WO2019083818A1 (en) 2017-10-23 2019-05-02 Novozymes A/S IMPROVING EXPRESSION OF PROTEASE BY CO-EXPRESSION WITH PROPEPTIDE
WO2019081724A1 (en) 2017-10-27 2019-05-02 Novozymes A/S VARIANTS OF DNASE
PL3476936T3 (pl) 2017-10-27 2022-04-11 The Procter & Gamble Company Kompozycje detergentu zawierające odmiany polipeptydowe
DE102017125560A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine iii enthalten
DE102017125559A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine ii enthalten
DE102017125558A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine i enthalten
MX2020004716A (es) 2017-11-06 2020-11-06 Janssen Biotech Inc Método seguro y eficaz para tratar la artritis psoriásica con el anticuerpo específico anti-il23.
KR20200095472A (ko) 2017-11-10 2020-08-10 디펜신 테라퓨틱스 에이피에스 조산아에서의 점막 방어 및 장/폐 기능의 성숙화
EP3707252A1 (de) 2017-11-10 2020-09-16 Novozymes A/S Temperaturempfindliches cas9-protein
CN111989400B (zh) 2017-11-14 2024-05-24 丹尼斯科美国公司 α-淀粉酶、组合物和方法
WO2019096903A1 (en) 2017-11-20 2019-05-23 Novozymes A/S New galactanases (ec 3.2.1.89) for use in soy processing
KR20200097251A (ko) 2017-11-24 2020-08-18 디펜신 테라퓨틱스 에이피에스 디펜신에 의한 이식편 대 숙주 질환의 예방 및 치료
US11725197B2 (en) 2017-12-04 2023-08-15 Novozymes A/S Lipase variants and polynucleotides encoding same
FI3720955T3 (fi) 2017-12-08 2023-09-05 Novozymes As Alfa-amylaasivariantteja ja niitä koodaavia polynukleotideja
ES2954431T3 (es) 2017-12-08 2023-11-22 Novozymes As Variantes de alfa-amilasa y polinucleótidos que codifican las mismas
WO2019125804A1 (en) 2017-12-20 2019-06-27 Basf Se Nucleases and methods for making and using them
WO2019122083A1 (en) 2017-12-22 2019-06-27 Novozymes A/S Wheat milling process and gh8 xylanases
MX2020007914A (es) 2018-01-29 2020-10-28 Novozymes As Microorganismos con uso de nitrogeno mejorado para produccion de etanol.
US20210123033A1 (en) 2018-02-08 2021-04-29 Novozymes A/S Lipases, Lipase Variants and Compositions Thereof
US20210071155A1 (en) 2018-02-08 2021-03-11 Novozymes A/S Lipase Variants and Compositions Thereof
US20190264140A1 (en) 2018-02-28 2019-08-29 The Procter & Gamble Company Methods of cleaning
JP7516250B2 (ja) 2018-03-05 2024-07-16 ヤンセン バイオテツク，インコーポレーテツド 抗ｉｌ－２３特異的抗体を用いたクローン病の治療方法
US11525151B2 (en) 2018-03-09 2022-12-13 Danisco Us Inc. Glucoamylases and methods of use, thereof
EP3765185B1 (de) 2018-03-13 2023-07-19 Novozymes A/S Mikroverkapselung unter verwendung von aminozuckeroligomeren
WO2019185726A1 (en) 2018-03-29 2019-10-03 Novozymes A/S Mannanase variants and polynucleotides encoding same
CN112105729B (zh) 2018-04-09 2024-05-14 诺维信公司 具有α-淀粉酶活性的多肽以及编码它们的多核苷酸
US11566239B2 (en) 2018-04-19 2023-01-31 Novozymes A/S Stabilized cellulase variants
CN112272701B (zh) 2018-04-19 2024-05-14 诺维信公司 稳定化的纤维素酶变体
WO2019224184A1 (en) 2018-05-21 2019-11-28 Ipsen Biopharm Limited Suppression of bone cancer-induced allodynia
BR112020022593A2 (pt) 2018-05-31 2021-02-09 Novozymes A/S método para tratar polpa de dissolução, polpa de dissolução, fibra têxtil ou celulose derivatizada, e, uso de uma monoxigenase lítica de polissacarídeo.
GB201809135D0 (en) 2018-06-04 2018-07-18 Sec Dep For Health Methods for detecting anitviral-drug resistant virus
WO2019243376A1 (en) 2018-06-18 2019-12-26 Ipsen Biopharm Limited Intramuscular injection of botulinum toxin for the treatment of vulvodynia
SG11202012529VA (en) 2018-06-27 2021-01-28 Boehringer Ingelheim Rcv Gmbh Means and methods for increased protein expression by use of transcription factors
WO2020002575A1 (en) 2018-06-28 2020-01-02 Novozymes A/S Polypeptides having pectin lyase activity and polynucleotides encoding same
CA3105609A1 (en) 2018-07-04 2020-01-09 Danisco Us Inc Glucoamylases and methods of use, thereof
WO2020016838A2 (en) 2018-07-18 2020-01-23 Janssen Biotech, Inc. Sustained response predictors after treatment with anti-il23 specific antibody
CN112601818A (zh) 2018-07-25 2021-04-02 诺维信公司 用于生产乙醇的表达酶的酵母
GB201812261D0 (en) 2018-07-27 2018-09-12 Micropharm Ltd Therapies for treating oral mucositis
GB201812262D0 (en) 2018-07-27 2018-09-12 Micropharm Ltd Therapies for treating proctitis
GB201813884D0 (en) 2018-08-24 2018-10-10 Sec Dep For Health Culture media
US11473076B2 (en) 2018-08-31 2022-10-18 Novozymes A/S Animal feed additives and compositions comprising an S8 serine protease
HUE063462T2 (hu) 2018-09-24 2024-01-28 Janssen Biotech Inc A colitis ulcerosa kezelésének biztonságos és hatékony eljárása anti-IL12/IL23 antitesttel
GB201815844D0 (en) 2018-09-28 2018-11-14 Ipsen Biopharm Ltd Therapeutic & comestic uses of botulinum neurotoxin serotype e
JP7604365B2 (ja) 2018-09-28 2024-12-23 イプセン バイオファーム リミテッド 細胞ベースのクロストリジウム神経毒アッセイ
GB201815817D0 (en) 2018-09-28 2018-11-14 Ispen Biopharm Ltd Clostridial neurotoxins comprising and exogenous activation loop
CN113056476A (zh) 2018-10-03 2021-06-29 诺维信公司 具有α-甘露聚糖降解活性的多肽以及编码它们的多核苷酸
WO2020070461A1 (en) 2018-10-04 2020-04-09 Secretary of State for Health and Social Care Immunoassay for detection of streptococcus pneumoniae serotypes
WO2020076697A1 (en) 2018-10-08 2020-04-16 Novozymes A/S Enzyme-expressing yeast for ethanol production
EP3874051A1 (de) 2018-10-31 2021-09-08 Novozymes A/S Genombearbeitung durch geführte endonuklease und einzelsträngiges oligonukleotid
MA55149A (fr) 2018-11-20 2021-09-29 Janssen Biotech Inc Procédé sûr et efficace de traitement du psoriasis avec un anticorps spécifique anti-il-23
US20220016221A1 (en) 2018-12-05 2022-01-20 Ipsen Biopharm Limited Treatment of symptoms of traumatic brain injury
WO2020123463A1 (en) 2018-12-12 2020-06-18 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
WO2020128864A1 (en) 2018-12-18 2020-06-25 Janssen Biotech, Inc. Safe and effective method of treating lupus with anti-il12/il23 antibody
EP3898962A2 (de) 2018-12-21 2021-10-27 Novozymes A/S Polypeptide mit peptidoglycanabbauender aktivität und polynukleotide zur codierung davon
GB201900621D0 (en) 2019-01-16 2019-03-06 Ipsen Biopharm Ltd Labelled polypeptides
WO2020160126A1 (en) 2019-01-31 2020-08-06 Novozymes A/S Polypeptides having xylanase activity and use thereof for improving the nutritional quality of animal feed
CN113840837A (zh) 2019-03-14 2021-12-24 詹森生物科技公司 用于产生抗tnf抗体组合物的方法
EP3938390A1 (de) 2019-03-14 2022-01-19 Janssen Biotech, Inc. Herstellungsverfahren zur herstellung von anti-tnf-antikörperzusammensetzungen
MA55283A (fr) 2019-03-14 2022-01-19 Janssen Biotech Inc Procédés de production de compositions d'anticorps anti-tnf
KR20210141990A (ko) 2019-03-14 2021-11-23 얀센 바이오테크 인코포레이티드 항-il12/il23 항체 조성물을 생성하기 위한 제조 방법
MX2021011328A (es) 2019-03-18 2021-12-10 Janssen Biotech Inc Método para tratar la psoriasis en sujetos pediátricos con anticuerpo anti-il12/il23.
BR112021018731A2 (pt) 2019-03-21 2021-12-21 Novozymes As Variantes de alfa-amilase e polinucleotídeos codificando as mesmas
CA3131705A1 (en) 2019-03-27 2020-10-01 Umc Utrecht Holding B.V. Engineered iga antibodies and methods of use
CN113785039B (zh) 2019-04-03 2024-06-18 诺维信公司 具有β-葡聚糖酶活性的多肽、编码其的多核苷酸及其在清洁和洗涤剂组合物中的用途
US12247237B2 (en) 2019-04-10 2025-03-11 Novozymes A/S Polypeptide variants
MX2021012289A (es) 2019-04-12 2021-11-12 Novozymes As Variantes de glucosido hidrolasa estabilizadas.
WO2020229191A1 (en) 2019-05-15 2020-11-19 Novozymes A/S Temperature-sensitive rna-guided endonuclease
GB201907016D0 (en) 2019-05-17 2019-07-03 Ipsen Biopharm Ltd Screening method to determine suitability for participation in a clinical trial
EP3972690A4 (de) 2019-05-23 2023-07-05 Janssen Biotech, Inc. Verfahren zur behandlung einer entzündlichen darmerkrankung mit einer kombinationstherapie von antikörpern gegen il-23 und tnf-alpha
US20200385453A1 (en) 2019-06-04 2020-12-10 Janssen Biotech, Inc. Safe and Effective Method of Treating Psoriatic Arthritis with Anti-IL23 Specific Antibody
GB201908155D0 (en) 2019-06-07 2019-07-24 Univ Warwick Leader sequence
EP3986996A1 (de) 2019-06-24 2022-04-27 The Procter & Gamble Company Reinigungszusammensetzungen mit amylasevarianten
US20220251528A1 (en) 2019-06-24 2022-08-11 Novozymes A/S Alpha-Amylase Variants
EP3994255A1 (de) 2019-07-02 2022-05-11 Novozymes A/S Lipasevarianten und zusammensetzungen davon
GB201909619D0 (en) 2019-07-04 2019-08-21 Univ Oxford Innovation Ltd Methods for diagnosing multiple sclerosis
EP4004211A1 (de) 2019-07-25 2022-06-01 Novozymes A/S Fadenpilzexpressionssystem
WO2021018751A1 (en) 2019-07-26 2021-02-04 Novozymes A/S Enzymatic treatment of paper pulp
MX2021015821A (es) 2019-07-26 2022-02-03 Novozymes As Microorganismos con transporte de nitrogeno mejorado para la produccion de etanol.
GB201911063D0 (en) 2019-08-02 2019-09-18 Tarian Biologics Ltd Formulations
GB201911064D0 (en) 2019-08-02 2019-09-18 Tarian Biologics Ltd Therapy
MX2021015818A (es) 2019-08-06 2022-02-03 Novozymes As Proteinas de fusion para mejorar la expresion de enzimas.
CN114364795A (zh) 2019-08-22 2022-04-15 巴斯夫欧洲公司 淀粉酶变体
EP4031661A1 (de) 2019-09-16 2022-07-27 Novozymes A/S Polypeptide mit beta-glucanase-aktivität und polynukleotide zur codierung davon
GB201913804D0 (en) 2019-09-25 2019-11-06 Prostate Cancer Res Centre Fusion polypeptides
GB201914034D0 (en) 2019-09-30 2019-11-13 Ipsen Biopharm Ltd Treatment of neurological disorders
EP4038170A1 (de) 2019-10-03 2022-08-10 Novozymes A/S Polypeptide mit mindestens zwei kohlenhydratbindungsdomänen
CA3158982A1 (en) 2019-12-10 2021-06-17 Monica TASSONE Microorganism for improved pentose fermentation
GB201918313D0 (en) 2019-12-12 2020-01-29 Lift Biosciences Ltd Cells for treating cancer
GB201918341D0 (en) 2019-12-12 2020-01-29 Lift Biosciences Ltd Cells for treating infections
US20230049145A1 (en) 2019-12-12 2023-02-16 Fresenius Kabi Deutschland Gmbh Glycosylated polypeptides
EP4077622A1 (de) 2019-12-19 2022-10-26 The Procter & Gamble Company Reinigungszusammensetzungen mit polypeptiden mit alpha-amylase-aktivität
WO2021123184A2 (en) 2019-12-19 2021-06-24 Novozymes A/S Alpha-amylase variants
CN114761551B (zh) 2019-12-19 2025-09-12 诺维信公司 木聚糖酶变体和编码其的多核苷酸
EP4077656A2 (de) 2019-12-20 2022-10-26 Novozymes A/S Polypeptide mit proteolytischer aktivität und verwendung davon
WO2021148278A1 (en) 2020-01-24 2021-07-29 Novozymes A/S Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide
EP4097226A1 (de) 2020-01-31 2022-12-07 Novozymes A/S Mannanase-varianten und dafür codierende polynukleotide
GB202001353D0 (en) 2020-01-31 2020-03-18 Ipsen Biopharm Ltd Treatment of skin conditions
WO2021152123A1 (en) 2020-01-31 2021-08-05 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2021163015A1 (en) 2020-02-10 2021-08-19 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
WO2021163030A2 (en) 2020-02-10 2021-08-19 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
MX2022009515A (es) 2020-02-10 2022-09-02 Novozymes As Variantes de alfa-amilasa y polinucleotidos que las codifican.
GB2594683A (en) 2020-02-17 2021-11-10 Vaxbio Ltd Vaccine
EP4110909A1 (de) 2020-02-26 2023-01-04 Novozymes A/S Polypeptidvarianten
GB202003611D0 (en) 2020-03-12 2020-04-29 Univ Oxford Innovation Ltd Stabilised viral fusion proteins
GB202003813D0 (en) 2020-03-16 2020-04-29 Ipsen Biopharm Ltd Treatment of upper facial lines
TW202426039A (zh) 2020-03-16 2024-07-01 英商艾普森生物製藥有限公司 肢體痙攣之治療
EP4133066A1 (de) 2020-04-08 2023-02-15 Novozymes A/S Kohlenhydratbindende modulvarianten
US12509670B2 (en) 2020-04-17 2025-12-30 Danisco Us Inc. Glucoamylase and methods of use thereof
CN115516071A (zh) 2020-04-21 2022-12-23 诺维信公司 包含具有果聚糖降解活性的多肽的清洁组合物
CA3181949A1 (en) 2020-05-05 2021-11-11 Janssen Biotech, Inc. Methods of treating crohn's disease with anti-il23 specific antibody
GB202006803D0 (en) 2020-05-07 2020-06-24 Imperial College Innovations Ltd Method for identifying RNA binding protein binding sites on RNA
CA3183927A1 (en) 2020-05-21 2021-11-25 Janssen Biotech, Inc. Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
TWI916375B (zh) 2020-06-25 2026-03-01 英商梅迪繆思有限公司 軸突損傷之預防
GB2596820A (en) 2020-07-07 2022-01-12 Spicona Inc Combination vaccine
AU2021308574A1 (en) 2020-07-13 2023-03-09 Janssen Biotech, Inc. Safe and effective method of treating psoriatic arthritis with anti-IL23 specific antibody
GB202010934D0 (en) 2020-07-15 2020-08-26 Ipsen Biopharm Ltd Controlling operation of a bioreactor vessel
GB202011055D0 (en) 2020-07-17 2020-09-02 Ipsen Bioinnovation Ltd Treatment of post-operative pain
WO2022013574A1 (en) 2020-07-17 2022-01-20 Imperial College Innovations Limited Hybrid double antigen sars-cov-2 antibody detection assay
GB202011902D0 (en) 2020-07-30 2020-09-16 Imperial College Innovations Ltd Antinobacillus pleuropneumoniae vaccines
WO2022024065A1 (en) 2020-07-30 2022-02-03 Janssen Biotech, Inc. Method of treating psoriasis in pediatric subjects with anti-il12/il23 antibody
EP4200424A1 (de) 2020-08-18 2023-06-28 Novozymes A/S Mit amylase-signalpeptiden exprimierte dispersine
JP7885201B2 (ja) 2020-08-25 2026-07-06 ノボザイムス アクティーゼルスカブ ファミリー４４キシログルカナーゼの変異体
EP4204548A1 (de) 2020-08-28 2023-07-05 Novozymes A/S Polyesterabbauende proteasevarianten
WO2022049403A1 (en) 2020-09-07 2022-03-10 Imperial College Innovations Limited Sars-cov-2 antibody detection assay
CN116829592A (zh) 2020-09-11 2023-09-29 免疫医疗有限公司 治疗性b7-h4结合分子
US20230365639A1 (en) 2020-09-14 2023-11-16 Aesculus Bio Aps Defensin fragment derived lipopeptides for treatment of drug-resistant microorganisms
CA3192419A1 (en) 2020-09-15 2022-03-24 Adam Byrne Treatment of idiopathic pulmonary fibrosis
GB202015618D0 (en) 2020-10-01 2020-11-18 Ipsen Biopharm Ltd Method for producing beta-trypsin
CN116507725A (zh) 2020-10-07 2023-07-28 诺维信公司 α-淀粉酶变体
US20230407273A1 (en) 2020-10-13 2023-12-21 Novozymes A/S Glycosyltransferase variants for improved protein production
GB202016349D0 (en) 2020-10-15 2020-12-02 Imp College Innovations Ltd Proteome analysis in pulmonary hypertension
EP4237525A1 (de) 2020-10-28 2023-09-06 Novozymes A/S Verwendung von lipoxygenase
WO2022090361A2 (en) 2020-10-29 2022-05-05 Novozymes A/S Lipase variants and compositions comprising such lipase variants
AU2021370998A1 (en) 2020-11-02 2023-05-25 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
US20240271175A1 (en) 2020-11-02 2024-08-15 Novozymes A/S Leader peptides and polynucleotides encoding the same
GB202017673D0 (en) 2020-11-09 2020-12-23 Imperial College Innovations Ltd Treatment of pulmonary arterial hypertensive
WO2022106404A1 (en) 2020-11-18 2022-05-27 Novozymes A/S Combination of proteases
WO2022106400A1 (en) 2020-11-18 2022-05-27 Novozymes A/S Combination of immunochemically different proteases
US20240052000A1 (en) 2020-12-15 2024-02-15 Novozymes A/S Mutated host cells with reduced cell motility on
WO2023225459A2 (en) 2022-05-14 2023-11-23 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
WO2023288294A1 (en) 2021-07-16 2023-01-19 Novozymes A/S Compositions and methods for improving the rainfastness of proteins on plant surfaces
GB202100566D0 (en) 2021-01-15 2021-03-03 Ipsen Biopharm Ltd Treatment of brain damage
EP4284905A1 (de) 2021-01-28 2023-12-06 Novozymes A/S Lipase mit geringer geruchsbildung
WO2022171780A2 (en) 2021-02-12 2022-08-18 Novozymes A/S Alpha-amylase variants
WO2022175440A1 (en) 2021-02-18 2022-08-25 Novozymes A/S Inactive heme polypeptides
EP4294917A1 (de) 2021-02-22 2023-12-27 Basf Se Amylasevarianten
EP4047088A1 (de) 2021-02-22 2022-08-24 Basf Se Amylasevarianten
GB202102832D0 (en) 2021-02-26 2021-04-14 Ip2Ipo Innovations Ltd Retroviral vectors
GB202103372D0 (en) 2021-03-11 2021-04-28 Ipsen Biopharm Ltd Modified clostridial neurotoxins
EP4305146A1 (de) 2021-03-12 2024-01-17 Novozymes A/S Polypeptidvarianten
EP4305062A1 (de) 2021-03-12 2024-01-17 Janssen Biotech, Inc. Verfahren zur behandlung von patienten mit psoriasisarthritis mit unzureichender reaktion auf eine tnf-therapie mit anti-il23-spezifischem antikörper
US20240060061A1 (en) 2021-03-15 2024-02-22 Novozymes A/S Dnase variants
MX2023005793A (es) 2021-03-15 2023-05-29 Procter & Gamble Composiciones de limpieza que contienen variantes de polipeptido.
EP4060036A1 (de) 2021-03-15 2022-09-21 Novozymes A/S Polypeptidvarianten
EP4308607A2 (de) 2021-03-18 2024-01-24 MedImmune Limited An ccr9 bindendes therapeutisches bindungsmolekül
WO2022199418A1 (en) 2021-03-26 2022-09-29 Novozymes A/S Detergent composition with reduced polymer content
GB202104294D0 (en) 2021-03-26 2021-05-12 Ipsen Biopharm Ltd Clostridial neurotoxins comprising an exogenous activation loop
JP2024513191A (ja) 2021-03-30 2024-03-22 イプセン バイオファーム リミテッド 疼痛及び炎症性障害の処置
CN117396217A (zh) 2021-03-30 2024-01-12 益普生生物制药有限公司 无催化活性的梭菌神经毒素用于疼痛和炎性疾病的治疗
US20240180197A1 (en) 2021-04-12 2024-06-06 Novozymes A/S Method for producing a meat analogue product
GB202105277D0 (en) 2021-04-13 2021-05-26 Imperial College Innovations Ltd Signal peptides
GB202105278D0 (en) 2021-04-13 2021-05-26 Imperial College Innovations Ltd Cell therapy
GB202105276D0 (en) 2021-04-13 2021-05-26 Imperial College Innovations Ltd Delivery of gene therapy vectors
CN117355608A (zh) 2021-05-27 2024-01-05 诺维信公司 转录调节物和编码其的多核苷酸
US20250011809A1 (en) 2021-05-27 2025-01-09 Cell Therapy Catapult Limited Viral vector production
BR112023025624A2 (pt) 2021-06-07 2024-02-27 Novozymes As Célula de levedura recombinante, célula hospedeira recombinante, composição, cocultura, métodos de produção de um derivado de uma célula hospedeira recombinante e de produção de um produto de fermentação, e, uso de uma célula hospedeira recombinante
CA3220135A1 (en) 2021-06-16 2022-12-22 Novozymes A/S Method for controlling slime in a pulp or paper making process
IL309996A (en) 2021-07-09 2024-03-01 Janssen Biotech Inc Production methods for the production of anti-TNF antibody compositions
CN117730090A (zh) 2021-07-13 2024-03-19 诺维信公司 重组角质酶表达
MA66538B1 (fr) 2021-09-16 2026-03-31 Ipsen Biopharm Limited Bont/a modifiée destinée à être utilisée dans le traitement de la dystonie cervicale
CA3228712A1 (en) 2021-09-23 2023-03-30 Nicolae GRIGORE Modified bont/a for use in the treatment of a disorder affecting an eyelid muscle of a subject
GB202113602D0 (en) 2021-09-23 2021-11-10 Ipsen Biopharm Ltd Treatment of a disorder affecting an eyelid muscle of a subject
US20240417709A1 (en) 2021-10-12 2024-12-19 Novozymes A/S Endoglucanase with improved stability
CA3234874A1 (en) 2021-10-15 2023-04-20 Martijn Scheffers Glucoamylase variants and methods for use thereof
US20250000816A1 (en) 2021-11-11 2025-01-02 Nutri-Gentix Limited Nutritional compositions
AU2022392458A1 (en) 2021-11-22 2024-05-02 Ipsen Biopharm Limited Treatment of pain
GB202116795D0 (en) 2021-11-22 2022-01-05 Ipsen Biopharm Ltd Treatment of visceral pain
WO2023104846A1 (en) 2021-12-10 2023-06-15 Novozymes A/S Improved protein production in recombinant bacteria
WO2023118871A1 (en) 2021-12-21 2023-06-29 Imperial College Innovations Limited Pseudotyped lentiviral vectors
WO2023118436A1 (en) 2021-12-22 2023-06-29 Novozymes A/S Method of producing a milk-based product
WO2023118565A1 (en) 2021-12-23 2023-06-29 Novozymes A/S Reduction of residual dna in microbial fermentation products
EP4475850A1 (de) 2022-02-09 2024-12-18 Imperial College Innovations Limited Behandlung von telangiectasie
EP4476240A1 (de) 2022-02-10 2024-12-18 Novozymes A/S Verbesserte expression rekombinanter proteine
WO2023161245A1 (en) 2022-02-22 2023-08-31 Novozymes A/S Oral care composition comprising enzymes
CN118660951A (zh) 2022-03-02 2024-09-17 诺维信公司 木葡聚糖酶用于改善洗涤剂的可持续性的用途
JP2025509233A (ja) 2022-03-08 2025-04-11 ノボザイムス アクティーゼルスカブ デアミダーゼ阻害剤及びデアミダーゼドメインを有する融合ポリペプチド
EP4242303A1 (de) 2022-03-08 2023-09-13 Novozymes A/S Fusionspolypeptide mit desamidasehemmer und desamidasedomänen
KR20240159839A (ko) 2022-03-09 2024-11-06 아스트라제네카 아베 FRα에 대한 결합 분자
EP4490517A1 (de) 2022-03-11 2025-01-15 Astrazeneca AB Bewertungsverfahren für eine anti-fr-alpha-antikörper-wirkstoff-konjugattherapie
AU2023253826A1 (en) 2022-04-11 2024-11-21 Boehringer Ingelheim International Gmbh Combination treatment
GB202206361D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of a facial dystonia
GB202206348D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of limb spasticity
GB202206353D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of cervical dystonia
GB202206362D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of upper facial lines
CN119053708A (zh) 2022-05-17 2024-11-29 诺维信公司 用于减少游离脂肪酸的方法
EP4544036A1 (de) 2022-06-21 2025-04-30 Novozymes A/S Mannanasevarianten und dafür codierende polynukleotide
WO2023247514A1 (en) 2022-06-22 2023-12-28 Novozymes A/S Recombinant mannanase expression
WO2023247664A2 (en) 2022-06-24 2023-12-28 Novozymes A/S Lipase variants and compositions comprising such lipase variants
EP4547210A1 (de) 2022-06-30 2025-05-07 Novozymes A/S Mutansasen und mundpflegezusammensetzungen damit
JP2025525309A (ja) 2022-07-15 2025-08-05 ノボザイムス アクティーゼルスカブ デアミダーゼ阻害剤活性を有するポリペプチド
WO2024033133A2 (en) 2022-08-11 2024-02-15 Basf Se Enzyme compositions comprising an amylase
JP2025526654A (ja) 2022-08-11 2025-08-15 ビーエーエスエフ ソシエタス・ヨーロピア プロテアーゼ、マンナナーゼ及び／又はセルラーゼを含む酵素組成物
GB202212472D0 (en) 2022-08-26 2022-10-12 Ip2Ipo Innovations Ltd Retroviral vectors
GB202213479D0 (en) 2022-09-14 2022-10-26 Ipsen Biopharm Ltd Cell-free clostridial neurotoxin assays
CN119948159A (zh) 2022-09-15 2025-05-06 诺维信公司 真菌信号肽
GB202213936D0 (en) 2022-09-23 2022-11-09 Imperial College Innovations Ltd Introns
GB202214232D0 (en) 2022-09-28 2022-11-09 Ispen Biopharm Ltd Clostridial neurotoxins comprising an activating exogenous protease cleavage site
GB202214229D0 (en) 2022-09-28 2022-11-09 Ipsen Biopharm Ltd Clostridial neurotoxins comprising an activating endosomal protease cleavage site
GB202214445D0 (en) 2022-09-30 2022-11-16 Imp College Innovations Ltd Gene therapy
EP4593873A1 (de) 2022-09-30 2025-08-06 Ipsen Biopharm Limited Clostridium-neurotoxin zur verwendung bei der behandlung von blasenschmerzsyndrom
GB202214720D0 (en) 2022-10-06 2022-11-23 Path Spray Ltd Compositions for detecting biological agents
WO2024118901A2 (en) 2022-11-30 2024-06-06 Novozymes A/S Carbonic anhydrase variants and polynucleotides encoding same
CN120989059A (zh) 2022-12-05 2025-11-21 诺维信公司 蛋白酶变体以及编码其的多核苷酸
WO2024120767A1 (en) 2022-12-05 2024-06-13 Novozymes A/S Modified rna polymerase activities
WO2024121191A1 (en) 2022-12-06 2024-06-13 Novozymes A/S Method for producing a meat analogue product involving protein-deamidase
EP4629838A1 (de) 2022-12-08 2025-10-15 Novozymes A/S Polypeptid mit lysozymaktivität und polynukleotide zur codierung davon
EP4629835A1 (de) 2022-12-08 2025-10-15 Novozymes A/S Faserabbauende enzyme für tierfutter mit ölsaatmaterial
EP4634355A1 (de) 2022-12-14 2025-10-22 Novozymes A/S Verbesserte lipase (gcl1)-varianten
CN120322453A (zh) 2022-12-14 2025-07-15 诺维信公司 高强度液体蛋白酶配制品
WO2024126811A1 (en) 2022-12-16 2024-06-20 Boehringer Ingelheim Rcv Gmbh & Co Kg Means and methods for increased protein expression by use of a combination of transport proteins and either chaperones or transcription factors
EP4634395A1 (de) 2022-12-16 2025-10-22 Basf Se Neue ethylendiamin-n,n'-dibernsteinsäure (edds) synthasen
EP4638725A1 (de) 2022-12-19 2025-10-29 Novozymes A/S Polypeptide der kohlenhydratesterasefamilie 3 (ce3) mit acetylxylanesteraseaktivität und polynukleotide zur codierung davon
CN120283060A (zh) 2022-12-19 2025-07-08 诺维信公司 用于使用纤维降解酶和工程化酵母生产发酵产物的工艺
CN120380140A (zh) 2022-12-19 2025-07-25 诺维信公司 具有阿魏酸酯酶和/或乙酰木聚糖酯酶活性的碳水化合物酯酶家族1（ce1）多肽和编码其的多核苷酸
WO2024133344A1 (en) 2022-12-20 2024-06-27 Novozymes A/S A method for providing a candidate biological sequence and related electronic device
EP4389864A1 (de) 2022-12-20 2024-06-26 Basf Se Cutinasen
WO2024133497A1 (en) 2022-12-21 2024-06-27 Novozymes A/S Recombinant protease for cell detachment
AU2023410701A1 (en) 2022-12-21 2025-05-22 Novo Nordisk Pharmatech A/S Microbial proteases for cell detachment
EP4389865A1 (de) 2022-12-21 2024-06-26 Novozymes A/S Rekombinante protease zur zellablösung
EP4389886A1 (de) 2022-12-22 2024-06-26 Novozymes A/S Lactaseenzyme und verfahren zur herstellung eines milchbasierten produkts
CN120435539A (zh) 2023-01-23 2025-08-05 诺维信公司 清洁组合物及其用途
TW202448517A (zh) 2023-02-16 2024-12-16 瑞典商阿斯特捷利康公司 用治療性結合分子治療癌症的組合療法
CN120417880A (zh) 2023-02-22 2025-08-01 诺维信公司 包含转化酶的口腔护理组合物
GB202303328D0 (en) 2023-03-07 2023-04-19 Imperial College Innovations Ltd Synthetic promoters
GB202304385D0 (en) 2023-03-24 2023-05-10 Prostate Cancer Res Combinatorial IL-15 therapy
GB202307439D0 (en) 2023-05-18 2023-07-05 Ipsen Biopharm Ltd Treatment of a headache disorder with botylinum neurotoxin a
AU2024303961A1 (en) 2023-06-13 2025-12-11 Novozymes A/S Processes for producing fermentation products using engineered yeast expressing a beta-xylosidase
EP4735563A1 (de) 2023-06-28 2026-05-06 Novozymes A/S Lipasen enthaltende waschmittelzusammensetzung
AU2024289271A1 (en) 2023-07-05 2025-11-27 Novozymes A/S Foamable dairy products
WO2025008364A1 (en) 2023-07-05 2025-01-09 Novozymes A/S Methods for obtaining plant-based ready-to-drink coffee or tea beverages
EP4273249A3 (de) 2023-07-07 2024-05-22 Novozymes A/S Verbesserte expression rekombinanter proteine
CN121464215A (zh) 2023-07-10 2026-02-03 诺维信公司 人工信号肽
WO2025032096A1 (en) 2023-08-09 2025-02-13 Novozymes A/S Methods for obtaining a plant-based food ingredient
AU2024325961A1 (en) 2023-08-15 2026-01-29 Novozymes A/S Polypeptides having alkaline phosphatase activity for animal feed
CN121620590A (zh) 2023-09-01 2026-03-06 诺维信公司 稳定的液体脱酰胺酶组合物
EP4777622A1 (de) 2023-09-13 2026-07-22 Novozymes A/S Stabilisierte deamidasezusammensetzungen
EP4780251A1 (de) 2023-09-19 2026-07-29 Novozymes A/S Verfahren zur beurteilung der proteinsubstratgelierung durch mikrobielle transglutaminase
WO2025068117A1 (en) 2023-09-26 2025-04-03 Novozymes A/S Using protein deamidase in processes for obtaining a seed-based dairy alternative beverage with improved stability
WO2024240965A2 (en) 2023-09-29 2024-11-28 Novozymes A/S Droplet-based screening method
CN122029266A (zh) 2023-10-24 2026-05-12 诺维信公司 木葡聚糖酶用于替代光学增亮剂的用途
WO2025093845A1 (en) 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of high dose chimeric botulinum toxin a for the treatment of upper facial lines
AU2023471835A1 (en) 2023-11-01 2026-04-30 Ipsen Biopharm Limited Use of chimeric botulinum toxin a for treating blepharospasm and hemifacial spasm
WO2025103765A1 (en) 2023-11-17 2025-05-22 Novozymes A/S Lytic polysaccharide monooxygenases and their use in detergent
WO2025111274A2 (en) 2023-11-20 2025-05-30 Novozymes A/S Epimerase variants and polynucleotides encoding same
CN122270290A (zh) 2023-11-30 2026-06-23 诺维信公司 包含肽酶或内酯酶的口腔护理组合物
GB202318884D0 (en) 2023-12-11 2024-01-24 Ipsen Biopharm Ltd Formulation
WO2025132815A1 (en) 2023-12-20 2025-06-26 Novozymes A/S Novel cas nucleases and polynucleotides encoding the same
WO2025133162A1 (en) 2023-12-20 2025-06-26 Novozymes A/S Recombinant protein expression
WO2025132872A1 (en) 2023-12-20 2025-06-26 Novozymes A/S Modified leguminous protein with improved colloidal stability
CN122374461A (zh) 2023-12-22 2026-07-10 诺维信公司 发酵方法
GB202320108D0 (en) 2023-12-28 2024-02-14 Ipsen Biopharm Ltd Biosensor
WO2025140303A1 (en) 2023-12-28 2025-07-03 Novozymes A/S Enzymatic treatment of a material comprising corn protein
WO2025168806A1 (en) 2024-02-08 2025-08-14 Novozymes A/S Polypeptides having carbonic anhydrase activity and polynucleotides encoding same
WO2025191164A2 (en) 2024-03-12 2025-09-18 Novozymes A/S Use of chymopapain in cell detachment
GB202404021D0 (en) 2024-03-20 2024-05-01 Ipsen Biopharm Ltd Cell-based neurotoxin assay
AU2025239494A1 (en) 2024-03-22 2026-06-25 Novozymes A/S Oral care compositions comprising dnases
WO2025217017A1 (en) 2024-04-08 2025-10-16 Novozymes A/S Compositions and methods for increasing phosphorous availability
WO2025226596A1 (en) 2024-04-24 2025-10-30 Novozymes A/S Methods for producing secreted polypeptides
WO2025229230A1 (en) 2024-05-03 2025-11-06 Novozymes A/S Combined carbon capture and soda ash process
WO2025233391A1 (en) 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
WO2025233389A1 (en) 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
EP4650443A1 (de) 2024-05-13 2025-11-19 Novozymes A/S Stabilisierte flüssige deamidasezusammensetzungen
WO2025242320A1 (en) 2024-05-21 2025-11-27 Novozymes A/S Stabilized ready-to-drink coffee beverages
WO2025247765A1 (en) 2024-05-30 2025-12-04 Chr. Hansen A/S Non-heated fermented meat analogue product prepared with vegetable protein transglutaminase and pediococcus strains
WO2025257254A1 (en) 2024-06-12 2025-12-18 Novozymes A/S Lipases and lipase variants and the use thereof
WO2026017381A1 (en) 2024-07-17 2026-01-22 Novozymes A/S Optimized bacillus host cells
WO2024254620A2 (en) 2024-08-01 2024-12-12 Novozymes A/S Protease for diagnostics
WO2026057740A1 (en) 2024-09-12 2026-03-19 Astrazeneca Ab Treatment of cancer with therapeutic binding molecules
WO2026062400A1 (en) 2024-09-19 2026-03-26 Lift Biosciences Ltd Preparation of cells
WO2026068782A1 (en) 2024-09-30 2026-04-02 Novozymes A/S Protease variants and polynucleotides encoding same
WO2026076952A1 (en) 2024-10-08 2026-04-16 Novozymes A/S Processes for obtaining dairy protein-based ready-to-drink beverages
WO2026099414A1 (en) 2024-11-08 2026-05-15 Novozymes A/S Method for producing gos syrup
WO2026104217A2 (en) 2024-11-12 2026-05-21 Basf Se Polypeptides having pectinase activity for use in cleaning compositions
WO2026109764A1 (en) 2024-11-22 2026-05-28 Novozymes A/S Stabilized solid formulation of antibodies
WO2026109480A1 (en) 2024-11-25 2026-05-28 Novozymes A/S Gh26 mannanases and their use in detergent
GB202417349D0 (en) 2024-11-26 2025-01-08 Nanosyrinx Ltd Method of purification
WO2026132184A1 (en) 2024-12-18 2026-06-25 Novozymes A/S Dispersin variants and their use in animal feed
WO2026132220A1 (en) 2024-12-18 2026-06-25 Novozymes A/S Gastric stable dispersin variants
WO2026131655A2 (en) 2024-12-18 2026-06-25 Basf Se Stable mannanase for blends
WO2026132030A1 (en) 2024-12-19 2026-06-25 Novozymes A/S Cas nucleases and polynucleotides encoding the same
WO2026131506A1 (en) 2024-12-20 2026-06-25 Basf Se Apolipoproteins for use in cleaning compositions
WO2026131444A1 (en) 2024-12-20 2026-06-25 Novozymes A/S Alpha-amylases, baking compositions and methods
WO2026139262A1 (en) 2024-12-23 2026-07-02 Basf Se Polypeptides having chitinase activity for use in cleaning compositions
WO2026159189A1 (en) 2025-01-24 2026-07-30 Novozymes A/S Method for producing hybrid meat
GB202501392D0 (en) 2025-01-30 2025-03-19 Imperial College Innovations Ltd Deuterated analogues

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988006630A1 (en) * 1987-03-02 1988-09-07 Genex Corporation Method for the preparation of binding molecules
JPH02500329A (ja) * 1987-05-21 1990-02-08 クリエイテイブ・バイオマリキユールズ・インコーポレーテツド ターゲット化多機能蛋白質
WO1989001526A1 (en) * 1987-08-07 1989-02-23 Genelabs Incorporated Coincidence cloning method and library
CA2016842A1 (en) * 1989-05-16 1990-11-16 Richard A. Lerner Method for tapping the immunological repertoire
CA2016841C (en) * 1989-05-16 1999-09-21 William D. Huse A method for producing polymers having a preselected activity
EP0478627A4 (en) * 1989-05-16 1992-08-19 William D. Huse Co-expression of heteromeric receptors

Also Published As

Publication number Publication date
CA2092802A1 (en) 1992-03-29
IL99552A0 (en) 1992-08-18
WO1992006204A1 (en) 1992-04-16
TW314553B (de) 1997-09-01
EP0550645B1 (de) 2001-08-22
DE69132700D1 (de) 2001-09-27
AU8731891A (en) 1992-04-28
EP0550645A1 (de) 1993-07-14
AU667291B2 (en) 1996-03-21
JP3373510B2 (ja) 2003-02-04
IE913425A1 (en) 1992-04-08
DE69132700T2 (de) 2001-12-06
EP0550645A4 (en) 1993-09-01
NZ239988A (en) 1995-06-27
JPH06505145A (ja) 1994-06-16
IE63054B1 (en) 1995-03-22

Similar Documents

Publication Publication Date Title
DE69132700D1 (de) Oberflächen lokalisierte expressionsbanken von heteromeren rezeptoren
FI894595L (fi) Gaspermeabel, vaetskeimpermeabel ovaevt material.
NO904777D0 (no) Belagt slipemateriale.
NO872261D0 (no) Belegningsmateriale.
FI892765L (fi) Kompositmaterial.
FI895072A0 (fi) Rullningsmaskin foer bandformigt material, saerskilt foer papper och kartong.
NO890156L (no) Opploesningsmiddelsvellede komposittmembraner.
DK2691A (da) Peptider, der binder retroviral protease
NO905176L (no) Belagte tekstilmaterialer.
NO901535L (no) Molekylaersikter og anvendelse derav som oksydasjonskatalysator.
DE69005415D1 (de) Kolonnen-Packungsmaterial.
DE69023911D1 (de) Flüssigkeitsapplikator.
DE68923037D1 (de) Harzhaltige Reinigungsmittelzusammensetzung.
BR8901275A (pt) Composicao detergente aquosa,abrasiva,homogenea,despejavel
DE69011142D1 (de) Kompositmaterial.
DE68901414D1 (de) Kohlenwasserstoff-dehydrierungsreakionen.
NO910826D0 (no) Fremgangsmaate ved bestemmelse av mettede forbindelser, olefiner og aromater i en blanding.
FI895405A0 (fi) Svaorantaendbara, hoegtemperaturbestaendiga pappersartade material baserade pao termostabila polymerer.
FI890583A0 (fi) Matrisformig foerevisningsanordning.
NO891172D0 (no) Basismateriale for overflatebelegg.
DK268290A (da) Anvendelse af kationiske, ikke-silikatiske lagforbindelser i vaskemidler
NO883886D0 (no) Flammehemmende ethylencopolymermateriale.
NO885128D0 (no) Enzymholdige, flytende vaskemiddelblandinger.
SE8800468D0 (sv) Banformat material, speciellt for anvendning som undertak
NO891651D0 (no) Polymere materialer.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties