ATE204756T1 - Phosphatbindende polymere für orale verabreichung - Google Patents

Phosphatbindende polymere für orale verabreichung

Info

Publication number
ATE204756T1
ATE204756T1 AT94925819T AT94925819T ATE204756T1 AT E204756 T1 ATE204756 T1 AT E204756T1 AT 94925819 T AT94925819 T AT 94925819T AT 94925819 T AT94925819 T AT 94925819T AT E204756 T1 ATE204756 T1 AT E204756T1
Authority
AT
Austria
Prior art keywords
oral administration
binding polymers
phosphate binding
polymers
phosphate
Prior art date
Application number
AT94925819T
Other languages
English (en)
Inventor
Stephen Randall Holmes-Farley
W Harry Mandeville Iii
George Mcclelland Whitesides
Original Assignee
Geltex Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26802726&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE204756(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Geltex Pharma Inc filed Critical Geltex Pharma Inc
Application granted granted Critical
Publication of ATE204756T1 publication Critical patent/ATE204756T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/795Polymers containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Epoxy Resins (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Polyurethanes Or Polyureas (AREA)
AT94925819T 1993-08-11 1994-08-10 Phosphatbindende polymere für orale verabreichung ATE204756T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10559193A 1993-08-11 1993-08-11
US08/238,458 US5496545A (en) 1993-08-11 1994-05-05 Phosphate-binding polymers for oral administration
PCT/US1994/009060 WO1995005184A2 (en) 1993-08-11 1994-08-10 Phosphate-binding polymers for oral administration

Publications (1)

Publication Number Publication Date
ATE204756T1 true ATE204756T1 (de) 2001-09-15

Family

ID=26802726

Family Applications (2)

Application Number Title Priority Date Filing Date
AT94925819T ATE204756T1 (de) 1993-08-11 1994-08-10 Phosphatbindende polymere für orale verabreichung
AT01200604T ATE324900T1 (de) 1993-08-11 1994-08-10 Polymer zur therapeutischen anwendung

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT01200604T ATE324900T1 (de) 1993-08-11 1994-08-10 Polymer zur therapeutischen anwendung

Country Status (15)

Country Link
US (1) US5496545A (de)
EP (3) EP1133989B1 (de)
JP (2) JP3113283B2 (de)
KR (1) KR100346766B1 (de)
AT (2) ATE204756T1 (de)
AU (1) AU689797B2 (de)
CA (3) CA2310960C (de)
DE (5) DE10299003I1 (de)
DK (2) DK0716606T3 (de)
ES (2) ES2260154T3 (de)
LU (2) LU90884I2 (de)
NL (2) NL300080I1 (de)
NZ (1) NZ271826A (de)
PT (2) PT1133989E (de)
WO (1) WO1995005184A2 (de)

Families Citing this family (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0684958T3 (da) * 1993-02-17 1998-10-19 Btg Int Ltd Polymerer indeholdende guanidinogrupper til anvendelse i terapi
US5487888A (en) 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
GB9503061D0 (en) * 1995-02-16 1995-04-05 British Tech Group Polymeric compounds
DE19528524C2 (de) * 1995-08-03 1999-11-11 Hans Dietl Calciumhaltiges Mittel zur intestinalen Phosphatbindung und Verfahren zu seiner Herstellung
TW528597B (en) * 1996-03-05 2003-04-21 Mitsubishi Electric Corp Medicament for preventive and/or therapeutic treatment of hyperphosphatemia
EP0922461A4 (de) * 1996-07-19 2002-07-17 Nikken Chemicals Co Ltd Heilmittel gegen hyperphosphatanämie
EP0934352B1 (de) * 1996-10-23 2007-05-02 Dow Global Technologies Inc. Wasserlösliche polymere für die verminderung der absorption von diätetikem phosphat oder oxalat
WO1998042355A1 (en) * 1997-03-25 1998-10-01 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers combined with a calcium supplement for oral administration
TW592727B (en) * 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US5985938A (en) 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6566407B2 (en) 1997-11-05 2003-05-20 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
AU2682499A (en) * 1998-02-17 1999-08-30 Dimitri R. Kioussis Anion binding polymers and the use thereof
WO1999047587A1 (en) * 1998-03-19 1999-09-23 Geltex Pharmaceuticals, Inc. Continuous crosslinking of polymer gels
US6294163B1 (en) 1998-10-02 2001-09-25 Geltex Pharmaceuticals, Inc. Polymers containing guanidinium groups as bile acid sequestrants
JP4749649B2 (ja) * 1998-10-12 2011-08-17 中外製薬株式会社 リン酸結合性ポリマー
TW568788B (en) 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US6271264B1 (en) 1998-12-01 2001-08-07 Geltex Pharmaceuticals, Inc. Polymers containing spirobicyclic ammonium moieties as bile acid sequestrants
PT1175451E (pt) * 1999-04-16 2007-09-24 Abbott Lab ''processo para produção de cloridrato de polialilamina reticulada''
US6190649B1 (en) 1999-04-23 2001-02-20 Geltex Pharmaceuticals, Inc. Polyether-based bile acid sequestrants
US6180754B1 (en) 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
US6362266B1 (en) 1999-09-03 2002-03-26 The Dow Chemical Company Process for reducing cohesiveness of polyallylamine polymer gels during drying
AU7856200A (en) * 1999-10-07 2001-05-10 University Of Maryland Sugar binding polymers and the use thereof
ATE311203T1 (de) * 1999-10-15 2005-12-15 Dow Global Technologies Inc Dialyselösung die polyglycol als osmotischen mittels enthält
US20030202958A1 (en) * 1999-10-15 2003-10-30 Strickland Alan D. Dialysis solution including polyglycol osmotic agent
AU778262B2 (en) * 1999-10-19 2004-11-25 Genzyme Corporation Direct compression polymer tablet core
US6733780B1 (en) * 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
AU2001241076A1 (en) * 2000-03-09 2001-09-17 Hisamitsu Pharmaceutical Co. Inc. Crosslinked anion-exchange resin or salt thereof
US6844372B2 (en) 2000-03-09 2005-01-18 Hisamitsu Pharmaceutical Co., Inc. Crosslinked anion-exchange resin or salt thereof and phosphorus adsorbent comprising the same
WO2001068106A1 (en) 2000-03-13 2001-09-20 Hisamitsu Pharmaceutical Co., Inc. Preventives and/or remedies for hyperphosphatemia
WO2002032974A2 (en) * 2000-10-18 2002-04-25 Fujisawa Pharmaceutical Co., Ltd. Polymer and its use for the treatment and/or prevention of hyperphosphoremia
US7199160B2 (en) * 2000-11-28 2007-04-03 Mitsubishi Pharma Corporation Antiobestic agents and health foods
AU2002224109A1 (en) * 2000-11-28 2002-06-11 Mitsubishi Pharma Corporation Excretion accelerator for accumulative chlorine compound
AT409630B (de) * 2000-12-13 2002-09-25 Dsm Fine Chem Austria Gmbh Alkylierung von n-bzw. amino- oder ammoniumgruppen haltigen, vernetzten polymeren
DE10065710A1 (de) * 2000-12-29 2002-07-04 Bayer Ag Arzneimittel enthaltend ein Polyamin als Wirksubstanz
US6710162B2 (en) 2001-02-16 2004-03-23 Genzyme Corporation Method of drying a material having a cohesive phase
NZ528829A (en) * 2001-04-18 2006-06-30 Genzyme Corp Low salt forms of polyallylamine
EP1923064B1 (de) 2001-04-18 2017-06-28 Genzyme Corporation Verwendung von Aminpolymeren zur Minderung des Serumglukosegehaltes
WO2002085382A1 (en) 2001-04-18 2002-10-31 Genzyme Corporation Methods of treating syndrome x with aliphatic polyamines
WO2002085379A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for improving vascular access in patients with vascular shunts
ES2637020T3 (es) * 2001-04-18 2017-10-10 Genzyme Corporation Uso de polímero de amina para reducir la glucosa sérica
MX2008011686A (es) * 2001-05-25 2010-05-27 Marathon Oil Co Inhibicion de sulfuracion del deposito utilizando una inyeccion de agua tratada.
US7041280B2 (en) * 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
JP2003033651A (ja) * 2001-07-24 2003-02-04 Chisso Corp 経口リン吸着剤及びそれを含む食品
WO2003011308A1 (en) * 2001-07-30 2003-02-13 Mitsubishi Pharma Corporation Drugs for ameliorating postcibal hyperglycemia
US6600011B2 (en) 2001-10-09 2003-07-29 Genzyme Corporation Process for purification and drying of polymer hydrogels
FR2833169B1 (fr) * 2001-12-07 2004-07-16 Oreal Composition filtrante contenant un derive de 1,3,5-triazine, un derive du dibenzoylmethane, et un derive de 2-hydroxybenzophenone aminosubstitue
US7119120B2 (en) * 2001-12-26 2006-10-10 Genzyme Corporation Phosphate transport inhibitors
EP2316468A1 (de) 2002-02-22 2011-05-04 Shire LLC Abgabesystem und Verfahren zum Schutz und zur Verabreichung von Dextroamphetamin
JP4465193B2 (ja) * 2002-03-19 2010-05-19 ジェンザイム コーポレーション リン酸塩輸送インヒビター
AT411463B (de) 2002-09-03 2004-01-26 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von alkylierten n- bzw. amino-, ammonium- oder spirobicyclischen ammoniumgruppen haltigen, vernetzten polymeren
AU2003282867A1 (en) * 2002-10-22 2004-05-13 Genzyme Corporation Amine polymers for promoting bone formation
AT412473B (de) 2003-01-15 2005-03-25 Dsm Fine Chem Austria Gmbh Verfahren zur kontinuierlichen trocknung von n- bzw. amino-, ammonium- oder spirobicyclische ammoniumgruppen haltigen polymeren
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) * 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US8519058B2 (en) * 2004-02-23 2013-08-27 E I Du Pont De Nemours And Company Crosslinked polymers containing biomass derived materials
US8426528B2 (en) * 2004-02-23 2013-04-23 E I Du Pont De Nemours And Company Preparation of crosslinked polymers containing biomass derived materials
ES2397159T3 (es) 2004-03-26 2013-03-05 Mitsubishi Tanabe Pharma Corporation Agente mejorador de la resistencia a insulina
EP3574896A1 (de) 2004-03-30 2019-12-04 Relypsa, Inc. Ionenbindende polymere und verwendungen davon
US20050276781A1 (en) * 2004-06-09 2005-12-15 Ross Edward A Molecularly imprinted phosphate binders for therapeutic use
AU2005290229A1 (en) * 2004-09-24 2006-04-06 Biosphere Medical, Inc. Microspheres capable of binding radioisotopes, optionally comprising metallic microparticles, and methods of use thereof
JP2008531751A (ja) * 2004-10-13 2008-08-14 イリプサ, インコーポレイテッド 架橋アミンポリマー
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
JP4547620B2 (ja) * 2004-12-02 2010-09-22 日東紡績株式会社 架橋アリルアミン類重合体の製造方法
ITME20040015A1 (it) * 2004-12-07 2005-03-07 Vincenzo Savica Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico.
WO2006072054A1 (en) * 2004-12-30 2006-07-06 Genzyme Corporation Zinc-containing treatments for hyperphosphatemia
CN101163731A (zh) * 2005-02-23 2008-04-16 纳幕尔杜邦公司 使用α,ω-二官能醛糖二酰胺作为单体和交联剂的方法
EP1869090A1 (de) * 2005-03-16 2007-12-26 Council Of Scientific And Industrial Research Verbessertes verfahren zur herstellung eines vernetzten polyallylaminpolymers
AU2006279429B2 (en) * 2005-08-17 2010-02-25 Hill's Pet Nutrition, Inc. Methods and compositions for the prevention and treatment of kidney disease
EP1951266A2 (de) * 2005-09-02 2008-08-06 Genzyme Corporation Verfahren zur entfernung von phosphat und dafür verwendetes polymer
AR056499A1 (es) * 2005-09-06 2007-10-10 Serapis Farmaceuticals Ltd Compuestos
AU2012205214B2 (en) * 2005-09-15 2015-05-21 Genzyme Corporation Formulation for Amine Polymers
PT1924246E (pt) 2005-09-15 2016-02-10 Genzyme Corp Formulação sachê para polímeros com funcionalidade amina
GB2446076B (en) 2005-09-30 2010-11-24 Ilypsa Inc Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
CA2624170C (en) 2005-09-30 2014-02-25 Ilypsa, Inc. Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal
CN101304739A (zh) * 2005-11-08 2008-11-12 基酶有限公司 用于治疗高磷酸盐血症的含镁聚合物
NZ569756A (en) * 2005-12-12 2011-07-29 Allaccem Inc Methods and systems for preparing antimicrobial films and coatings utilising polycyclic bridged ammonium salts
ITRM20060204A1 (it) * 2006-04-10 2007-10-11 Vincenzo Savica Farmaci e alimentei per diete normoproteiche iperproteiche ipopro teiche tutte ipofosforiche e bevande ipofosforiche
WO2007130463A2 (en) * 2006-05-05 2007-11-15 Genzyme Corporation Amine condensation polymers as phosphate sequestrants
ES2398477T3 (es) 2006-06-16 2013-03-19 Mitsubishi Tanabe Pharma Corporation Agente para la prevención y/o el tratamiento de glomerulopatía
US20100135950A1 (en) * 2006-07-05 2010-06-03 Genzyme Corporation Iron(II)-Containing Treatments for Hyperphosphatemia
AU2007275711A1 (en) * 2006-07-18 2008-01-24 Genzyme Corporation Amine dendrimers
JP5301273B2 (ja) 2006-08-09 2013-09-25 田辺三菱製薬株式会社 錠剤
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
WO2008062437A2 (en) * 2006-09-01 2008-05-29 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
WO2008042222A2 (en) 2006-09-29 2008-04-10 Genzyme Corporation Amide dendrimer compositions
ES2573636T3 (es) 2006-10-25 2016-06-09 Wisconsin Alumni Research Foundation Métodos para reducir la absorción de fosfato empleando un anticuerpo anti-Npt2B
AU2007309026B2 (en) 2006-10-26 2013-09-12 Aovatechnologies, Inc. Methods of reducing phosphate absorption
EP2120972A1 (de) 2006-12-14 2009-11-25 Genzyme Corporation Amido-amin-polymerzusammensetzungen
JP2008169758A (ja) * 2007-01-11 2008-07-24 Bosch Corp ターボチャージャ駆動制御方法及びその装置
EP2125026B1 (de) 2007-02-21 2014-09-24 AllAccem, Inc. Auf verbrückter polycyclischer verbindung basierende zusammensetzungen zur hemmung und linderung von erkrankungen
EP2114376A1 (de) * 2007-02-23 2009-11-11 Genzyme Corporation Amin-polymerzusammensetzungen
EP2131820A1 (de) * 2007-03-08 2009-12-16 Genzyme Corporation Sulfonpolymerzusammensetzungen
US8034833B2 (en) * 2008-03-20 2011-10-11 Biolink Life Sciences, Inc. Phosphorus binder for treatment of renal disease
US20100166696A1 (en) * 2007-04-27 2010-07-01 Dhal Pradeep K Amido-amine dendrimer compositions
KR20100045965A (ko) 2007-07-11 2010-05-04 도레이 카부시키가이샤 가교 폴리알릴아민 또는 그 산부가염 및 그 의약 용도
EP2016947A1 (de) * 2007-07-17 2009-01-21 Chemo Ibérica, S.A. Neuartiges Verfahren zur Herstellung vernetzter Poly(allylamin-)Polymere in einem einzigen Schritt
WO2009023544A2 (en) * 2007-08-10 2009-02-19 Ilypsa, Inc. Dosage unit anion-exchange polymer pharmaceutical compositions
US8188068B2 (en) * 2007-08-10 2012-05-29 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in pets
US8153617B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in humans
US8153618B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for topical applications for pets
US20090074833A1 (en) * 2007-08-17 2009-03-19 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling bone resorption
TWI592159B (zh) 2007-11-16 2017-07-21 威佛(國際)股份有限公司 藥學組成物
EP2217215A1 (de) * 2007-12-14 2010-08-18 Genzyme Corporation Beschichtete pharmazeutische zusammensetzungen
US8389640B2 (en) * 2008-04-15 2013-03-05 Lupin Limited Process for the preparation of cross-linked polyallylamine polymer
US20100016270A1 (en) * 2008-06-20 2010-01-21 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling cholesterol levels
US20100004218A1 (en) * 2008-06-20 2010-01-07 Whiteford Jeffery A Bridged polycyclic compound based compositions for renal therapy
WO2009154747A1 (en) * 2008-06-20 2009-12-23 Genzyme Corporation Pharmaceutical compositions
DE102008030046A1 (de) 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
US8404784B2 (en) * 2008-12-03 2013-03-26 Navinta Llc Manufacturing process of making polymeric amine salts
US20100166861A1 (en) * 2008-12-29 2010-07-01 Kelly Noel Lynch Pharmaceutical formulations of sevalamer, or salts thereof, and copovidone
CA2749397A1 (en) 2009-01-22 2010-08-05 Usv Limited Pharmaceutical compositions comprising phosphate-binding polymer
AU2010261339A1 (en) 2009-06-16 2012-01-19 Watson Pharma Private Limited Processes for the preparation of sevelamer carbonate
US8673272B2 (en) * 2009-07-27 2014-03-18 Isp Investments Inc. Ultraviolet-absorbing compounds
GB0921951D0 (en) * 2009-12-16 2010-02-03 Fujifilm Mfg Europe Bv Curable compositions and membranes
JP5377265B2 (ja) * 2009-12-16 2013-12-25 一般財団法人川村理化学研究所 ポリマー/酒石酸結晶性ナノ複合体及びその製造方法
ES2414383T5 (es) 2010-01-15 2016-12-12 Graphic Packaging International, Inc. Garra de cadena continua para cajas de cartón octogonales
CN105017481B (zh) 2010-02-24 2018-10-02 瑞立普萨公司 用作胆汁酸螯合剂的交联聚乙烯胺、聚烯丙胺和乙烯亚胺
JP5717422B2 (ja) * 2010-11-30 2015-05-13 株式会社パイロットコーポレーション ゲル状組成物の製造方法
IT1404163B1 (it) * 2011-02-01 2013-11-15 Chemi Spa Processo per la preparazione di poliallilamine reticolate o loro sali farmaceuticamente accettabili
DK2672945T3 (en) 2011-02-09 2016-03-21 Synthon Bv STABILIZED PACKAGING TYPES OF sevelamer.
CN102796262B (zh) * 2011-05-24 2014-11-12 北大方正集团有限公司 一种碳酸司维拉姆的制备方法
WO2013064193A1 (en) 2011-11-04 2013-05-10 Synthon Bv Pharmaceutical compositions comprising sevelamer
US20130123433A1 (en) 2011-11-14 2013-05-16 Formosa Laboratories, Inc. Method for preparing poly(allylamine) hydrochloride and derivatives therefrom
WO2013087237A1 (en) 2011-12-13 2013-06-20 Synthon Bv Purification of sevelamer and related polyallylamines
EP2791183A1 (de) 2011-12-13 2014-10-22 Synthon BV Herstellung von sevelamer mit vermindertem allylamingehalt
CN102675510B (zh) * 2012-05-28 2014-04-02 诚达药业股份有限公司 司维拉姆的合成工艺
ES2471340B1 (es) 2012-12-21 2015-08-17 Laboratorios Rubió, S.A. Composición farmacéutica oral para fármacos de elevada posología
CN105263477B (zh) 2013-03-13 2019-01-15 生物领域医疗公司 用于放射性同位素结合微粒的组合物和相关方法
CN103446179B (zh) * 2013-05-14 2017-03-15 厦门绿洲安源投资管理有限公司 作为磷酸盐、脂肪酸和胆汁酸绑定螯合剂的双亲聚富勒烯树状交联聚阳离子凝胶的应用
SI3287133T1 (sl) 2013-06-05 2019-09-30 Tricida Inc. Polimeri, ki vežejo protone,za peroralno dajanje
EP3593808B1 (de) 2014-12-10 2020-12-09 Tricida Inc. Protonenbindende polymere zur oralen verabreichung
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
CN105985448B (zh) 2015-03-20 2018-09-18 杨达志 多糖-聚胺共聚物及其质子化的阳离子共聚物、制备方法及作为磷酸盐移除剂的应用
CA2980472C (en) 2015-03-20 2023-08-29 Howard University Microcarriers, matrices and scaffolds for culturing mammalian cells and methods of manufacture
US10245284B2 (en) 2015-08-19 2019-04-02 Alpex Pharma S.A. Granular composition for oral administration
DK3426608T3 (da) 2016-03-08 2021-08-09 Technion Res & Dev Foundation Desinfektion og fjernelse af nitrogenarter fra saltvands-akvakultursystemer
BR112018072714A2 (pt) 2016-05-06 2019-02-19 Tricida, Inc. composições de ligação a hcl para e método de tratamento de distúrbios de ácido-base
WO2018124264A1 (ja) 2016-12-28 2018-07-05 富士フイルム株式会社 窒素原子含有ポリマー又はその塩の乳化液、その製造方法、及び粒子の製造方法
CN107412166B (zh) * 2017-08-08 2020-03-24 同济大学 一种纳米复合吸附磷材料及其制备与应用
US10934380B1 (en) 2017-09-25 2021-03-02 Tricida, Inc. Crosslinked poly(allylamine) polymer pharmaceutical compositions
JP7018451B2 (ja) 2017-10-16 2022-02-10 富士フイルム株式会社 高リン血症治療剤および粒子
EP3698799B1 (de) * 2017-10-16 2022-01-26 FUJIFILM Corporation Mittel zur behandlung von hyperphosphatämie
US10479865B2 (en) 2017-11-01 2019-11-19 Strides Shasun Limited Process for the preparation of sevelamer carbonate
SG11202003451UA (en) 2017-11-03 2020-05-28 Tricida Inc Compositions for and method of treating acid-base disorders
CN112047854B (zh) * 2020-10-20 2021-07-02 中国科学院长春应用化学研究所 一种n-乙烯基烷基酰胺的制备方法
EP4295836A1 (de) 2022-06-22 2023-12-27 Labomed Pharmaceutical Company S.A. Beutel mit einer flüssigen suspension eines sevelamersalzes
EP4605439A1 (de) * 2022-10-20 2025-08-27 Universiteit Gent Verfahren zur herstellung amidierter polymere

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE580490A (fr) * 1958-07-15 1960-01-08 Merck & Co Inc Compositions et procédés pour abaisser la teneur en cholestérol du sang
US3308020A (en) * 1961-09-22 1967-03-07 Merck & Co Inc Compositions and method for binding bile acids in vivo including hypocholesteremics
US3332841A (en) * 1961-10-04 1967-07-25 Lilly Co Eli Method of treating hyperacidity
DE1927336A1 (de) * 1968-06-17 1969-12-18 Upjohn Co Orale Dosierungsform zur Bekaempfung von Hypercholesterinaemie
US3980770A (en) * 1971-06-04 1976-09-14 Pharmacia Aktiebolag Polymerization products containing amino groups useful in serum cholesterol level control
DK136015B (da) * 1973-02-09 1977-08-01 Sandoz Ag Fremgangsmåde til fremstilling af en aluminiumhydrogel til anvendelse som phosphatbindingsmiddel.
AR206115A1 (es) * 1973-06-11 1976-06-30 Merck & Co Inc Procedimiento para preparar un polimero lineal no ramificado y no reticulado
US4205064A (en) * 1973-06-11 1980-05-27 Merck & Co., Inc. Bile acid sequestering composition containing poly[{alkyl-(3-ammoniopropyl)imino}-trimethylenedihalides]
US4016209A (en) * 1975-04-23 1977-04-05 Merck & Co., Inc. 3-[N'-(3-Halopropyl)-N-'-methylamino]-N,N,N-trimethyl-1-propanaminium halide and acid addition salts thereof
US4181718A (en) * 1975-12-29 1980-01-01 Mason Norbert S Polyanion-stabilized aluminum hydrogels
US4071478A (en) * 1976-06-07 1978-01-31 Merck & Co., Inc. Controlled partially cross-linked 3,3-ionenes
DE2741323A1 (de) * 1977-03-10 1978-09-14 Werner Klaus Konzack Raederfahrzeug
US4143130A (en) * 1977-08-29 1979-03-06 Warren-Teed Laboratories, Inc. Method for treating kidney stones
JPS5566513A (en) * 1978-11-14 1980-05-20 Ono Pharmaceut Co Ltd Drug for arteriosclerosis comprising high polymer compound as active constituent
US4247393A (en) * 1979-01-11 1981-01-27 Wallace Richard A Hemodialysis assist device
ATE12511T1 (de) * 1980-12-12 1985-04-15 Smith & Nephew Ass Polymere, deren herstellung und verwendungen.
JPS6090243A (ja) * 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
OA08092A (fr) * 1984-05-11 1987-03-31 Bristol Myers Co Novel bile sequestrant resin and uses.
US4631305A (en) * 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
JPS62132830A (ja) * 1985-12-05 1987-06-16 Teijin Ltd 徐放性医薬品組成物
DE68913602T2 (de) * 1988-07-13 1994-06-16 Collaborative Biomed Prod Gewebe-Immobilisierungs- und Zellkultursystem und Verfahren zum Anbringen biologisch wirksamer Teile an einem Substrat.
KR900701285A (ko) * 1988-08-26 1990-12-01 로버어트 에이 아미테이지 미세-구슬상 콜레스티폴 염산염
GB8829835D0 (en) * 1988-12-21 1989-02-15 Smith Kline French Lab Compounds
DE3901527A1 (de) * 1989-01-20 1990-07-26 Hoechst Ag Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate
US5053423A (en) * 1990-03-22 1991-10-01 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
JPH0687974B2 (ja) * 1990-03-27 1994-11-09 忠一 平山 発熱物質の吸着材料
JPH0424180A (ja) * 1990-05-16 1992-01-28 Daikin Ind Ltd クローラ式小型運搬機
AU659106B2 (en) * 1990-11-06 1995-05-11 Fgn, Inc. Method for treating colonic polyps by the use of esters and amides of substituted phenyl and pyridyl amino carboxylates
IE914179A1 (en) * 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
JP2785529B2 (ja) * 1991-08-21 1998-08-13 日東紡績株式会社 エタノール徐放剤およびそれを用いた食品保存用組成物
EP0534304A1 (de) * 1991-09-21 1993-03-31 Hoechst Aktiengesellschaft Cycloalkylierte Polyethyleniminderivate und ihre Verwendung als Hypolipidämika
SE470006B (sv) * 1991-09-26 1993-10-25 Corline Systems Ab Nytt konjugat, dess framställning och användning samt substrat preparerat med konjugatet
AU3592693A (en) * 1992-01-21 1993-08-03 University Of Utah, The Method and composition for heparin binding using polyaminocations covalently immobilised on polymeric surfaces with polyethylene oxide spacers
WO1993022380A1 (en) * 1992-05-06 1993-11-11 Isp Investments Inc. Polymers of vinyl-pyrrolidone and aminoalkyl acrylamides
DE4227019A1 (de) * 1992-08-14 1994-02-17 Geckeler Kurt E Priv Doz Dr Herstellung und Modifikation von Materialien auf der Basis von Amino- oder Amidpolymeren
SK31395A3 (en) * 1992-08-20 1995-08-09 Du Pont Crosslinked polymeric ammonium salts
US5302531A (en) * 1992-10-22 1994-04-12 Miles Inc. Composition for the semiquantitative determination of specific gravity of a test sample
DK0684958T3 (da) * 1993-02-17 1998-10-19 Btg Int Ltd Polymerer indeholdende guanidinogrupper til anvendelse i terapi
JPH09500368A (ja) * 1993-06-02 1997-01-14 ジェルテックス ファーマシューティカルズ,インコーポレイテッド 胆汁酸塩を除去するための組成物および方法

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CA2402590A1 (en) 1995-02-23
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