DK1133989T3 - Polymersammensætning til anvendelse i terapi - Google Patents

Polymersammensætning til anvendelse i terapi

Info

Publication number
DK1133989T3
DK1133989T3 DK01200604T DK01200604T DK1133989T3 DK 1133989 T3 DK1133989 T3 DK 1133989T3 DK 01200604 T DK01200604 T DK 01200604T DK 01200604 T DK01200604 T DK 01200604T DK 1133989 T3 DK1133989 T3 DK 1133989T3
Authority
DK
Denmark
Prior art keywords
therapy
polymer composition
phosphate
polymers
hyperphosphatemia
Prior art date
Application number
DK01200604T
Other languages
English (en)
Inventor
Stephen Randall Holmes-Farley
Harry W Mandeville Iii
George Mcclelland Whitesides
Original Assignee
Genzyme Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26802726&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1133989(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genzyme Corp filed Critical Genzyme Corp
Application granted granted Critical
Publication of DK1133989T3 publication Critical patent/DK1133989T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/795Polymers containing sulfur
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/12Drugs for disorders of the metabolism for electrolyte homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Resins (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Polyesters Or Polycarbonates (AREA)
DK01200604T 1993-08-11 1994-08-10 Polymersammensætning til anvendelse i terapi DK1133989T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10559193A 1993-08-11 1993-08-11
US08/238,458 US5496545A (en) 1993-08-11 1994-05-05 Phosphate-binding polymers for oral administration
EP94925819A EP0716606B1 (en) 1993-08-11 1994-08-10 Phosphate-binding polymers for oral administration

Publications (1)

Publication Number Publication Date
DK1133989T3 true DK1133989T3 (da) 2006-09-11

Family

ID=26802726

Family Applications (2)

Application Number Title Priority Date Filing Date
DK94925819T DK0716606T3 (da) 1993-08-11 1994-08-10 Phosphatbindende polymerer til oral indgivelse
DK01200604T DK1133989T3 (da) 1993-08-11 1994-08-10 Polymersammensætning til anvendelse i terapi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK94925819T DK0716606T3 (da) 1993-08-11 1994-08-10 Phosphatbindende polymerer til oral indgivelse

Country Status (15)

Country Link
US (1) US5496545A (da)
EP (3) EP0716606B1 (da)
JP (2) JP3113283B2 (da)
KR (1) KR100346766B1 (da)
AT (2) ATE324900T1 (da)
AU (1) AU689797B2 (da)
CA (3) CA2402590A1 (da)
DE (5) DE10299003I1 (da)
DK (2) DK0716606T3 (da)
ES (2) ES2161780T3 (da)
LU (2) LU90884I2 (da)
NL (2) NL300080I1 (da)
NZ (1) NZ271826A (da)
PT (2) PT1133989E (da)
WO (1) WO1995005184A2 (da)

Families Citing this family (157)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU692432B2 (en) * 1993-02-17 1998-06-11 British Technology Group Limited Polymeric compounds
US5487888A (en) * 1993-05-20 1996-01-30 Geltex, Inc. Iron-binding polymers for oral administration
US5667775A (en) 1993-08-11 1997-09-16 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers for oral administration
GB9503061D0 (en) * 1995-02-16 1995-04-05 British Tech Group Polymeric compounds
DE19528524C2 (de) * 1995-08-03 1999-11-11 Hans Dietl Calciumhaltiges Mittel zur intestinalen Phosphatbindung und Verfahren zu seiner Herstellung
ES2162658T3 (es) * 1996-03-05 2002-01-01 Mitsubishi Chem Corp Utilizacion de resinas intercambiadoras anionicas para la fabricacion de un medicamento destinado al tratamiento de la hiperfosfatemia.
EP0922461A4 (en) * 1996-07-19 2002-07-17 Nikken Chemicals Co Ltd MEDICINE AGAINST HYPERPHOSPHATANEMIA
EP0934352B1 (en) * 1996-10-23 2007-05-02 Dow Global Technologies Inc. Water-soluble polymers for the reduction of dietary phosphate or oxalate absorption
WO1998042355A1 (en) * 1997-03-25 1998-10-01 Geltex Pharmaceuticals, Inc. Phosphate-binding polymers combined with a calcium supplement for oral administration
TW592727B (en) * 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
US6423754B1 (en) * 1997-06-18 2002-07-23 Geltex Pharmaceuticals, Inc. Method for treating hypercholesterolemia with polyallylamine polymers
NZ516848A (en) * 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
US6726905B1 (en) 1997-11-05 2004-04-27 Genzyme Corporation Poly (diallylamines)-based phosphate binders
US6566407B2 (en) 1997-11-05 2003-05-20 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
US5985938A (en) * 1997-11-05 1999-11-16 Geltex Pharmaceuticals, Inc. Method for reducing oxalate
AU2682499A (en) * 1998-02-17 1999-08-30 Dimitri R. Kioussis Anion binding polymers and the use thereof
WO1999047587A1 (en) * 1998-03-19 1999-09-23 Geltex Pharmaceuticals, Inc. Continuous crosslinking of polymer gels
US6294163B1 (en) 1998-10-02 2001-09-25 Geltex Pharmaceuticals, Inc. Polymers containing guanidinium groups as bile acid sequestrants
JP4749649B2 (ja) * 1998-10-12 2011-08-17 中外製薬株式会社 リン酸結合性ポリマー
TW568788B (en) * 1998-10-12 2004-01-01 Chugai Pharmaceutical Co Ltd Polymer combining with phosphoric acid and preparation containing the same
US6271264B1 (en) 1998-12-01 2001-08-07 Geltex Pharmaceuticals, Inc. Polymers containing spirobicyclic ammonium moieties as bile acid sequestrants
WO2000063259A1 (en) * 1999-04-16 2000-10-26 Abbott Laboratories Process for producing cross-linked polyallylamine hydrochloride
US6190649B1 (en) 1999-04-23 2001-02-20 Geltex Pharmaceuticals, Inc. Polyether-based bile acid sequestrants
US6180754B1 (en) 1999-09-03 2001-01-30 The Dow Chemical Company Process for producing cross-linked polyallylamine polymer
US6362266B1 (en) 1999-09-03 2002-03-26 The Dow Chemical Company Process for reducing cohesiveness of polyallylamine polymer gels during drying
WO2001025291A1 (en) * 1999-10-07 2001-04-12 University Of Maryland Sugar binding polymers and the use thereof
ATE311203T1 (de) * 1999-10-15 2005-12-15 Dow Global Technologies Inc Dialyselösung die polyglycol als osmotischen mittels enthält
US20030202958A1 (en) * 1999-10-15 2003-10-30 Strickland Alan D. Dialysis solution including polyglycol osmotic agent
US20020054903A1 (en) * 1999-10-19 2002-05-09 Joseph Tyler Direct compression polymer tablet core
US6733780B1 (en) 1999-10-19 2004-05-11 Genzyme Corporation Direct compression polymer tablet core
KR100794427B1 (ko) * 1999-10-19 2008-01-16 젠자임 코포레이션 직접 압축형 중합체 정제 코어
AU2001241076A1 (en) * 2000-03-09 2001-09-17 Hisamitsu Pharmaceutical Co. Inc. Crosslinked anion-exchange resin or salt thereof
AU2001241077A1 (en) 2000-03-09 2001-09-17 Hisamitsu Pharmaceutical Co. Inc. Crosslinked anion-exchange resin or salt thereof and phosphorus adsorbent comprising the same
AU2001241095A1 (en) 2000-03-13 2001-09-24 Hisamitsu Pharmaceutical Co. Inc. Preventives and/or remedies for hyperphosphatemia
WO2002032974A2 (en) * 2000-10-18 2002-04-25 Fujisawa Pharmaceutical Co., Ltd. Polymer and its use for the treatment and/or prevention of hyperphosphoremia
WO2002043761A1 (en) * 2000-11-28 2002-06-06 Mitsubishi Pharma Corporation Antiobestic agents and health foods
WO2002043744A1 (fr) * 2000-11-28 2002-06-06 Mitsubishi Pharma Corporation Accelerateur d'excretion pour compose chlore accumule
AT409630B (de) * 2000-12-13 2002-09-25 Dsm Fine Chem Austria Gmbh Alkylierung von n-bzw. amino- oder ammoniumgruppen haltigen, vernetzten polymeren
DE10065710A1 (de) * 2000-12-29 2002-07-04 Bayer Ag Arzneimittel enthaltend ein Polyamin als Wirksubstanz
US6710162B2 (en) 2001-02-16 2004-03-23 Genzyme Corporation Method of drying a material having a cohesive phase
EP1379259A1 (en) * 2001-04-18 2004-01-14 Genzyme Corporation Methods of treating syndrome x with aliphatic polyamines
AU2002252632B2 (en) * 2001-04-18 2004-09-23 Genzyme Corporation Low salt forms of polyallylamine
WO2002085379A1 (en) * 2001-04-18 2002-10-31 Geltex Pharmaceuticals, Inc. Method for improving vascular access in patients with vascular shunts
EP1923064B1 (en) 2001-04-18 2017-06-28 Genzyme Corporation Use of amine polymer for lowering serum glucose
CA2444046C (en) * 2001-04-18 2011-06-07 Steven K. Burke Use of colesevelam in reducing serum glucose
MX2008011686A (es) * 2001-05-25 2010-05-27 Marathon Oil Co Inhibicion de sulfuracion del deposito utilizando una inyeccion de agua tratada.
US7041280B2 (en) * 2001-06-29 2006-05-09 Genzyme Corporation Aryl boronate functionalized polymers for treating obesity
JP2003033651A (ja) * 2001-07-24 2003-02-04 Chisso Corp 経口リン吸着剤及びそれを含む食品
US7879869B2 (en) 2001-07-30 2011-02-01 Mitsubishi Tanabe Pharma Corporation Drugs for ameliorating postcibal hyperglycemia
US6600011B2 (en) 2001-10-09 2003-07-29 Genzyme Corporation Process for purification and drying of polymer hydrogels
FR2833169B1 (fr) * 2001-12-07 2004-07-16 Oreal Composition filtrante contenant un derive de 1,3,5-triazine, un derive du dibenzoylmethane, et un derive de 2-hydroxybenzophenone aminosubstitue
US7119120B2 (en) * 2001-12-26 2006-10-10 Genzyme Corporation Phosphate transport inhibitors
EP2316468A1 (en) 2002-02-22 2011-05-04 Shire LLC Delivery system and methods for protecting and administering dextroamphetamine
ATE337326T1 (de) * 2002-03-19 2006-09-15 Genzyme Corp Hemmer des phosphattransports
AT411463B (de) 2002-09-03 2004-01-26 Dsm Fine Chem Austria Gmbh Verfahren zur herstellung von alkylierten n- bzw. amino-, ammonium- oder spirobicyclischen ammoniumgruppen haltigen, vernetzten polymeren
US7220406B2 (en) * 2002-10-22 2007-05-22 Genzyme Corporation Method for promoting bone formation
AT412473B (de) 2003-01-15 2005-03-25 Dsm Fine Chem Austria Gmbh Verfahren zur kontinuierlichen trocknung von n- bzw. amino-, ammonium- oder spirobicyclische ammoniumgruppen haltigen polymeren
US7335795B2 (en) 2004-03-22 2008-02-26 Ilypsa, Inc. Crosslinked amine polymers
US7608674B2 (en) * 2003-11-03 2009-10-27 Ilypsa, Inc. Pharmaceutical compositions comprising cross-linked small molecule amine polymers
US7449605B2 (en) * 2003-11-03 2008-11-11 Ilypsa, Inc. Crosslinked amine polymers
US7767768B2 (en) * 2003-11-03 2010-08-03 Ilypsa, Inc. Crosslinked amine polymers
US7385012B2 (en) 2003-11-03 2008-06-10 Ilypsa, Inc. Polyamine polymers
US7459502B2 (en) * 2003-11-03 2008-12-02 Ilypsa, Inc. Pharmaceutical compositions comprising crosslinked polyamine polymers
WO2005082978A1 (en) * 2004-02-23 2005-09-09 E.I. Dupont De Nemours And Company Preparation of crosslinked polymers containing biomass derived materials
EP1732973A1 (en) * 2004-02-23 2006-12-20 E.I.Du pont de nemours and company Crosslinked polymers containing biomass derived materials
CN1953756A (zh) 2004-03-26 2007-04-25 三菱制药株式会社 胰岛素抗性改善剂
PT2184059E (pt) 2004-03-30 2012-07-06 Relypsa Inc Polímeros de ligação a ião e seus usos
US20050276781A1 (en) * 2004-06-09 2005-12-15 Ross Edward A Molecularly imprinted phosphate binders for therapeutic use
JP5079510B2 (ja) * 2004-09-24 2012-11-21 バイオスフィア メディカル, インコーポレイテッド 放射性同位体を結合し得、任意選択的に金属微粒子を含むミクロスフェア、およびそれらの使用方法
CA2583634C (en) * 2004-10-13 2013-03-19 Ilypsa, Inc. Crosslinked amine polymers
US20060177415A1 (en) * 2004-11-01 2006-08-10 Burke Steven K Once a day formulation for phosphate binders
US7985418B2 (en) 2004-11-01 2011-07-26 Genzyme Corporation Aliphatic amine polymer salts for tableting
JP4547620B2 (ja) * 2004-12-02 2010-09-22 日東紡績株式会社 架橋アリルアミン類重合体の製造方法
ITME20040015A1 (it) * 2004-12-07 2005-03-07 Vincenzo Savica Chewing gum, caramelle gommose, pastiglie, compresse a lento rilascio di chelanti fosfato e/o fosforo salivare e capsule a lento rilascio di chelanti fosfato e/o fosforo a livello gastroenterico.
WO2006072054A1 (en) * 2004-12-30 2006-07-06 Genzyme Corporation Zinc-containing treatments for hyperphosphatemia
EP1858955A1 (en) * 2005-02-23 2007-11-28 E.I. Dupont De Nemours And Company Processes using alpha, omega-difunctional aldaramides as monomers and crosslinkers
CA2601236A1 (en) * 2005-03-16 2006-09-21 Usv Limited An improved process for the preparation of crosslinked polyallylamine polymer
US8492432B2 (en) * 2005-08-17 2013-07-23 Hill's Pet Nutrition, Inc. Methods for the treatment of kidney disease
US8986669B2 (en) * 2005-09-02 2015-03-24 Genzyme Corporation Method for removing phosphate and polymer used therefore
AR056499A1 (es) * 2005-09-06 2007-10-10 Serapis Farmaceuticals Ltd Compuestos
AU2012205214B2 (en) * 2005-09-15 2015-05-21 Genzyme Corporation Formulation for Amine Polymers
EP3000460A1 (en) * 2005-09-15 2016-03-30 Genzyme Corporation Sachet formulation for amine polymers
CA2624112A1 (en) 2005-09-30 2007-04-05 Ilypsa, Inc. Methods for preparing core-shell composites having cross-linked shells and core-shell composites resulting therefrom
GB2446077B (en) 2005-09-30 2010-10-13 Ilypsa Inc Methods and compositions for selectively removing potassium ion from the gastrointestinal tract of a mammal
EP1945196A2 (en) * 2005-11-08 2008-07-23 Genzyme Corporation Magnesium-containing polymers for hyperphosphatemia
NZ569756A (en) 2005-12-12 2011-07-29 Allaccem Inc Methods and systems for preparing antimicrobial films and coatings utilising polycyclic bridged ammonium salts
ITRM20060204A1 (it) * 2006-04-10 2007-10-11 Vincenzo Savica Farmaci e alimentei per diete normoproteiche iperproteiche ipopro teiche tutte ipofosforiche e bevande ipofosforiche
EP2016114A2 (en) * 2006-05-05 2009-01-21 Genzyme Corporation Amine condensation polymers as phosphate sequestrants
ES2398477T3 (es) 2006-06-16 2013-03-19 Mitsubishi Tanabe Pharma Corporation Agente para la prevención y/o el tratamiento de glomerulopatía
WO2008005217A2 (en) * 2006-07-05 2008-01-10 Genzyme Corporation Iron(ii)-containing treatments for hyperphosphatemia
AU2007275711A1 (en) * 2006-07-18 2008-01-24 Genzyme Corporation Amine dendrimers
EP2050456A4 (en) 2006-08-09 2013-01-23 Mitsubishi Tanabe Pharma Corp COMPRESSED
US7964182B2 (en) * 2006-09-01 2011-06-21 USV, Ltd Pharmaceutical compositions comprising phosphate-binding polymer
CA2749074A1 (en) * 2006-09-01 2008-05-29 Usv Limited Process for the preparation of sevelamer hydrochloride and formulation thereof
EP2066293A2 (en) 2006-09-29 2009-06-10 Genzyme Corporation Amide dendrimer compositions
CN101568349B (zh) 2006-10-25 2012-09-19 威斯康星大学校友研究基金会 减少磷酸盐吸收的方法
JP2010508281A (ja) 2006-10-26 2010-03-18 ウィスコンシン・アラムナイ・リサーチ・ファウンデイション リン酸塩吸収の低減方法
US8163799B2 (en) * 2006-12-14 2012-04-24 Genzyme Corporation Amido-amine polymer compositions
JP2008169758A (ja) * 2007-01-11 2008-07-24 Bosch Corp ターボチャージャ駆動制御方法及びその装置
CA2683383C (en) 2007-02-21 2016-01-05 Allaccem, Incorporated Bridged polycyclic compound based compositions for the inhibition and amelioration of disease
JP2010519298A (ja) * 2007-02-23 2010-06-03 ゲンズイメ コーポレーション アミンポリマー組成物
EP2131820A1 (en) * 2007-03-08 2009-12-16 Genzyme Corporation Sulfone polymer compositions
US8034833B2 (en) * 2008-03-20 2011-10-11 Biolink Life Sciences, Inc. Phosphorus binder for treatment of renal disease
EP2152277A1 (en) * 2007-04-27 2010-02-17 Genzyme Corporation Amido-amine dendrimer compositions
BRPI0813928A2 (pt) 2007-07-11 2014-12-30 Toray Industries Polialilamina reticulada, composição farmacêutica, agente terapêutico ou profilático para hiperfosfatemia, método terapêutico ou profilático para hiperfosfatemia, uso da polialilamina reticulada, e, composto para terapia ou profilaxia de hiperfosfatemia
EP2016947A1 (en) * 2007-07-17 2009-01-21 Chemo Ibérica, S.A. Novel one step process for preparing cross-linked poly(allylamine) polymers
US8188068B2 (en) * 2007-08-10 2012-05-29 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in pets
WO2009023544A2 (en) * 2007-08-10 2009-02-19 Ilypsa, Inc. Dosage unit anion-exchange polymer pharmaceutical compositions
US8153617B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for coating oral surfaces in humans
US8153618B2 (en) * 2007-08-10 2012-04-10 Allaccem, Inc. Bridged polycyclic compound based compositions for topical applications for pets
US20090074833A1 (en) * 2007-08-17 2009-03-19 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling bone resorption
TWI592159B (zh) 2007-11-16 2017-07-21 威佛(國際)股份有限公司 藥學組成物
WO2009078958A1 (en) * 2007-12-14 2009-06-25 Genzyme Corporation Coated pharmaceutical compositions
WO2009128085A1 (en) * 2008-04-15 2009-10-22 Lupin Limited Process for the preparation of cross-linked polyallylamine polymer
US20100004218A1 (en) * 2008-06-20 2010-01-07 Whiteford Jeffery A Bridged polycyclic compound based compositions for renal therapy
US20110142952A1 (en) * 2008-06-20 2011-06-16 Harris David J Pharmaceutical Compositions
US20100016270A1 (en) * 2008-06-20 2010-01-21 Whiteford Jeffery A Bridged polycyclic compound based compositions for controlling cholesterol levels
DE102008030046A1 (de) 2008-06-25 2009-12-31 Ratiopharm Gmbh Kompaktiertes Polyallylamin-Polymer
US8404784B2 (en) * 2008-12-03 2013-03-26 Navinta Llc Manufacturing process of making polymeric amine salts
US20100166861A1 (en) * 2008-12-29 2010-07-01 Kelly Noel Lynch Pharmaceutical formulations of sevalamer, or salts thereof, and copovidone
US20110081413A1 (en) * 2009-01-22 2011-04-07 Ashok Omray Pharmaceutical Compositions Comprising Phosphate-Binding Polymer
WO2010146603A1 (en) 2009-06-16 2010-12-23 Watson Pharma Private Limited Processes for the preparation of sevelamer carbonate
US8673272B2 (en) * 2009-07-27 2014-03-18 Isp Investments Inc. Ultraviolet-absorbing compounds
JP5377265B2 (ja) * 2009-12-16 2013-12-25 一般財団法人川村理化学研究所 ポリマー/酒石酸結晶性ナノ複合体及びその製造方法
GB0921951D0 (en) * 2009-12-16 2010-02-03 Fujifilm Mfg Europe Bv Curable compositions and membranes
EP2345590B2 (en) 2010-01-15 2016-07-27 Graphic Packaging International, Inc. Flight lug for octagonal cartons
WO2011106542A2 (en) 2010-02-24 2011-09-01 Relypsa, Inc. Crosslinked polyvrnylamine, poly all ylamine, and polyethyleneimine for use as bile acid sequestrants
JP5717422B2 (ja) * 2010-11-30 2015-05-13 株式会社パイロットコーポレーション ゲル状組成物の製造方法
IT1404163B1 (it) * 2011-02-01 2013-11-15 Chemi Spa Processo per la preparazione di poliallilamine reticolate o loro sali farmaceuticamente accettabili
DK2672945T3 (da) 2011-02-09 2016-03-21 Synthon Bv Stabiliserede pakningsformer af sevelamer.
CN102796262B (zh) * 2011-05-24 2014-11-12 北大方正集团有限公司 一种碳酸司维拉姆的制备方法
EP2773329B1 (en) 2011-11-04 2016-01-13 Synthon BV Pharmaceutical compositions comprising sevelamer
US20130123433A1 (en) 2011-11-14 2013-05-16 Formosa Laboratories, Inc. Method for preparing poly(allylamine) hydrochloride and derivatives therefrom
WO2013087237A1 (en) 2011-12-13 2013-06-20 Synthon Bv Purification of sevelamer and related polyallylamines
RU2014128587A (ru) 2011-12-13 2016-02-10 Синтон Б.В. Получение севеламера с пониженным содержанием аллиламина
CN102675510B (zh) * 2012-05-28 2014-04-02 诚达药业股份有限公司 司维拉姆的合成工艺
ES2471340B1 (es) 2012-12-21 2015-08-17 Laboratorios Rubió, S.A. Composición farmacéutica oral para fármacos de elevada posología
WO2014159759A1 (en) 2013-03-13 2014-10-02 Biosphere Medical, Inc. Compositions and associated methods for radioisotope-binding microparticles
CN103446179B (zh) * 2013-05-14 2017-03-15 厦门绿洲安源投资管理有限公司 作为磷酸盐、脂肪酸和胆汁酸绑定螯合剂的双亲聚富勒烯树状交联聚阳离子凝胶的应用
SI3287133T1 (sl) 2013-06-05 2019-09-30 Tricida Inc. Polimeri, ki vežejo protone,za peroralno dajanje
LT3229816T (lt) 2014-12-10 2020-05-25 Tricida Inc. Protoną prijungiantys polimerai, skirti peroraliniam įvedimui
MA41202A (fr) 2014-12-18 2017-10-24 Genzyme Corp Copolymères polydiallymine réticulé pour le traitement du diabète de type 2
CN107530370B (zh) 2015-03-20 2021-01-26 杨达志 用于培养哺乳动物细胞的微载体、基质和支架及其制造方法
WO2016150342A1 (zh) 2015-03-20 2016-09-29 杨达志 多糖-聚氨共聚物及其在降低血浆中低密度脂蛋白浓度的应用
US10245284B2 (en) 2015-08-19 2019-04-02 Alpex Pharma S.A. Granular composition for oral administration
WO2017153986A1 (en) 2016-03-08 2017-09-14 Technion Research & Development Foundation Limited Disinfection and removal of nitrogen species from saline aquaculture systems
WO2017193024A1 (en) 2016-05-06 2017-11-09 Tricida, Inc. Hcl-binding compositions for and method of treating acid-base disorders
BR112019013364A2 (pt) 2016-12-28 2020-04-14 Fujifilm Corp emulsão de polímero contendo átomo de nitrogênio ou sal do mesmo, método de produção para o mesmo e método de produção para partículas
CN107412166B (zh) * 2017-08-08 2020-03-24 同济大学 一种纳米复合吸附磷材料及其制备与应用
US10934380B1 (en) 2017-09-25 2021-03-02 Tricida, Inc. Crosslinked poly(allylamine) polymer pharmaceutical compositions
TW201922268A (zh) 2017-10-16 2019-06-16 日商富士軟片股份有限公司 高磷血症治療劑及粒子
CN111225674A (zh) * 2017-10-16 2020-06-02 富士胶片株式会社 高磷血症治疗剂
US10479865B2 (en) 2017-11-01 2019-11-19 Strides Shasun Limited Process for the preparation of sevelamer carbonate
IL319146A (en) 2017-11-03 2025-04-01 Tricida Inc Compositions for and method of treating acid-base disorders
CN112047854B (zh) * 2020-10-20 2021-07-02 中国科学院长春应用化学研究所 一种n-乙烯基烷基酰胺的制备方法
EP4295836A1 (en) 2022-06-22 2023-12-27 Labomed Pharmaceutical Company S.A. Sachet comprising a liquid suspension of a sevelamer salt
WO2024084076A1 (en) * 2022-10-20 2024-04-25 Universiteit Gent Method to prepare amidated polymers

Family Cites Families (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE580490A (fr) * 1958-07-15 1960-01-08 Merck & Co Inc Compositions et procédés pour abaisser la teneur en cholestérol du sang
US3308020A (en) * 1961-09-22 1967-03-07 Merck & Co Inc Compositions and method for binding bile acids in vivo including hypocholesteremics
US3332841A (en) * 1961-10-04 1967-07-25 Lilly Co Eli Method of treating hyperacidity
DE1927336A1 (de) * 1968-06-17 1969-12-18 Upjohn Co Orale Dosierungsform zur Bekaempfung von Hypercholesterinaemie
US3980770A (en) * 1971-06-04 1976-09-14 Pharmacia Aktiebolag Polymerization products containing amino groups useful in serum cholesterol level control
DK136015B (da) * 1973-02-09 1977-08-01 Sandoz Ag Fremgangsmåde til fremstilling af en aluminiumhydrogel til anvendelse som phosphatbindingsmiddel.
US4205064A (en) * 1973-06-11 1980-05-27 Merck & Co., Inc. Bile acid sequestering composition containing poly[{alkyl-(3-ammoniopropyl)imino}-trimethylenedihalides]
AR206115A1 (es) * 1973-06-11 1976-06-30 Merck & Co Inc Procedimiento para preparar un polimero lineal no ramificado y no reticulado
US4016209A (en) * 1975-04-23 1977-04-05 Merck & Co., Inc. 3-[N'-(3-Halopropyl)-N-'-methylamino]-N,N,N-trimethyl-1-propanaminium halide and acid addition salts thereof
US4181718A (en) * 1975-12-29 1980-01-01 Mason Norbert S Polyanion-stabilized aluminum hydrogels
US4071478A (en) * 1976-06-07 1978-01-31 Merck & Co., Inc. Controlled partially cross-linked 3,3-ionenes
DE2741323A1 (de) * 1977-03-10 1978-09-14 Werner Klaus Konzack Raederfahrzeug
US4143130A (en) * 1977-08-29 1979-03-06 Warren-Teed Laboratories, Inc. Method for treating kidney stones
JPS5566513A (en) * 1978-11-14 1980-05-20 Ono Pharmaceut Co Ltd Drug for arteriosclerosis comprising high polymer compound as active constituent
US4247393A (en) * 1979-01-11 1981-01-27 Wallace Richard A Hemodialysis assist device
ATE12511T1 (de) * 1980-12-12 1985-04-15 Smith & Nephew Ass Polymere, deren herstellung und verwendungen.
JPS6090243A (ja) * 1983-10-25 1985-05-21 Nitto Boseki Co Ltd 小球状モノアリルアミン橋かけ重合体の製造方法
EP0162388B1 (en) * 1984-05-11 1989-09-13 Bristol-Myers Company Novel bile sequestrant resin and uses
US4631305A (en) * 1985-03-22 1986-12-23 The Upjohn Company Polymeric material as a disintegrant in a compressed tablet
JPS62132830A (ja) * 1985-12-05 1987-06-16 Teijin Ltd 徐放性医薬品組成物
DE68913602T2 (de) * 1988-07-13 1994-06-16 Collaborative Biomed Prod Gewebe-Immobilisierungs- und Zellkultursystem und Verfahren zum Anbringen biologisch wirksamer Teile an einem Substrat.
WO1990002148A1 (en) * 1988-08-22 1990-03-08 The Upjohn Company Fine-beaded colestipol hydrochloride
GB8829835D0 (en) * 1988-12-21 1989-02-15 Smith Kline French Lab Compounds
DE3901527A1 (de) * 1989-01-20 1990-07-26 Hoechst Ag Alkylierte polyethyleniminderivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel sowie pharmazeutische praeparate
US5053423A (en) * 1990-03-22 1991-10-01 Quadra Logic Technologies Inc. Compositions for photodynamic therapy
JPH0687974B2 (ja) * 1990-03-27 1994-11-09 忠一 平山 発熱物質の吸着材料
JPH0424180A (ja) * 1990-05-16 1992-01-28 Daikin Ind Ltd クローラ式小型運搬機
AU659106B2 (en) * 1990-11-06 1995-05-11 Fgn, Inc. Method for treating colonic polyps by the use of esters and amides of substituted phenyl and pyridyl amino carboxylates
IE914179A1 (en) * 1990-12-07 1992-06-17 Ici Plc Nitrogen derivatives
JP2785529B2 (ja) * 1991-08-21 1998-08-13 日東紡績株式会社 エタノール徐放剤およびそれを用いた食品保存用組成物
EP0534304A1 (de) * 1991-09-21 1993-03-31 Hoechst Aktiengesellschaft Cycloalkylierte Polyethyleniminderivate und ihre Verwendung als Hypolipidämika
SE470006B (sv) * 1991-09-26 1993-10-25 Corline Systems Ab Nytt konjugat, dess framställning och användning samt substrat preparerat med konjugatet
WO1993014127A1 (en) * 1992-01-21 1993-07-22 University Of Utah Method and composition for heparin binding using polyaminocations covalently immobilised on polymeric surfaces with polyethylene oxide spacers
AU4225993A (en) * 1992-05-06 1993-11-29 Isp Investments Inc. Polymers of vinyl-pyrrolidone and aminoalkyl acrylamides
DE4227019A1 (de) * 1992-08-14 1994-02-17 Geckeler Kurt E Priv Doz Dr Herstellung und Modifikation von Materialien auf der Basis von Amino- oder Amidpolymeren
JPH08500386A (ja) * 1992-08-20 1996-01-16 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー 架橋ポリマーアンモニウム塩
US5302531A (en) * 1992-10-22 1994-04-12 Miles Inc. Composition for the semiquantitative determination of specific gravity of a test sample
AU692432B2 (en) * 1993-02-17 1998-06-11 British Technology Group Limited Polymeric compounds
AU7047994A (en) * 1993-06-02 1994-12-20 Geltex Pharmaceuticals, Inc. Compositions and process for removing bile salts

Also Published As

Publication number Publication date
EP1676581A3 (en) 2008-12-03
DE122009000081I1 (de) 2010-04-29
PT1133989E (pt) 2006-08-31
EP1133989A2 (en) 2001-09-19
CA2310960C (en) 2003-05-27
JP3113283B2 (ja) 2000-11-27
HK1009243A1 (en) 1999-05-28
CA2169356A1 (en) 1995-02-23
KR960703607A (ko) 1996-08-31
EP1676581A2 (en) 2006-07-05
JPH09504782A (ja) 1997-05-13
JP2001055336A (ja) 2001-02-27
LU90884I2 (en) 2002-03-25
WO1995005184A2 (en) 1995-02-23
ES2161780T3 (es) 2001-12-16
DE69428122T2 (de) 2002-04-18
DE10299003I1 (de) 2002-05-08
EP1133989B1 (en) 2006-05-03
PT716606E (pt) 2002-02-28
DE10299003I2 (de) 2006-07-13
KR100346766B1 (ko) 2003-10-04
EP0716606A4 (en) 1999-12-22
ES2260154T3 (es) 2006-11-01
US5496545A (en) 1996-03-05
WO1995005184A3 (en) 1995-03-23
NL300428I1 (nl) 2010-02-01
EP1133989A3 (en) 2004-05-12
HK1036753A1 (en) 2002-01-18
CA2310960A1 (en) 1995-02-23
DE69434726T2 (de) 2007-01-18
EP0716606A1 (en) 1996-06-19
NL300080I1 (nl) 2002-04-02
ATE204756T1 (de) 2001-09-15
NZ271826A (en) 2000-06-23
AU689797B2 (en) 1998-04-09
DE69434726D1 (de) 2006-06-08
CA2169356C (en) 2000-07-04
EP0716606B1 (en) 2001-08-29
DK0716606T3 (da) 2001-12-17
CA2402590A1 (en) 1995-02-23
AU7560794A (en) 1995-03-14
LU91629I2 (fr) 2011-08-25
ATE324900T1 (de) 2006-06-15
DE69428122D1 (de) 2001-10-04

Similar Documents

Publication Publication Date Title
DK1133989T3 (da) Polymersammensætning til anvendelse i terapi
DE69432559D1 (de) Verwendung von eisenbindenden polymeren zur herstellung eines medikaments zur oralen verabreichung
WO1996039156A3 (en) Phosphate-binding polymers for oral administration
BR0112799A (pt) Composição farmacêutica, processo para preparação e utilização da mesma, conjunto e processo para tratamento de obesidade, utilização de um inibidor de lìpase e de um sequestrante de ácido de bìlis e processo de tratamento ou prevencão de efeitos colaterais gastrointestinais
EP1138673A3 (en) Novel carbamates and ureas as modifiers of multi-drug resistance
SI1465626T1 (sl) Farmacevtski sestavki (komplet), ki obsegajo dihidropiridionske spojine in imunoregulacijsko (ali protivnetno) sredstvo, in njihove uporabe
AU1975295A (en) Antithrombotic agents
CA2163361A1 (en) Therapeutic substituted guanidines
BR9914044A (pt) ésteres tetrahidropirido
NO20002547D0 (no) Poly(vinylamin)-baserte superabsorberende geler og fremgangsmÕte for fremstilling derav
ATE106737T1 (de) Pharmazeutische zusammensetzungen zur behandlung gastrointestinaler störungen.
NZ330944A (en) Peptide derivatives
BR9814945A (pt) Utilização de fanquinona para o tratamento de doença de alzheimer, composição farmacêutica e kit
TR199802200A2 (xx) S�lfonamid s�bstit�e edilmi� benzopiran t�revleri, �retilme y�ntemi.
ZA979338B (en) Peptide compounds.
WO2001030334A3 (en) 6-methoxy-2-naphthylacetic acid prodrugs compositions for treating inflammation
TR199701605A2 (xx) S�lfonamid-substit�e edilmi� bile�ikler
MY114084A (en) Phosphate - binding polymers for oral administration
MX9705305A (es) Polimeros fijadores de fosfato para administracion oral.