ATE214104T1 - Verfahren zur charakterisierung von nukleinsäuremolekulen, das die erzeugung von verlängerbaren aufwärtsgelegenen dns-fragmenten, die durch spaltung der nukleinsäure an einer abasischen stelle entsteht, umfasst - Google Patents

Verfahren zur charakterisierung von nukleinsäuremolekulen, das die erzeugung von verlängerbaren aufwärtsgelegenen dns-fragmenten, die durch spaltung der nukleinsäure an einer abasischen stelle entsteht, umfasst

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Publication number
ATE214104T1
ATE214104T1 AT98917568T AT98917568T ATE214104T1 AT E214104 T1 ATE214104 T1 AT E214104T1 AT 98917568 T AT98917568 T AT 98917568T AT 98917568 T AT98917568 T AT 98917568T AT E214104 T1 ATE214104 T1 AT E214104T1
Authority
AT
Austria
Prior art keywords
nucleic acid
dna
site
cliving
abase
Prior art date
Application number
AT98917568T
Other languages
English (en)
Inventor
Thomas Valentine Mccarthy
Patrick Martin Vaughan
Original Assignee
Entpr Ie Trd As Bioresearch Ie
Univ College Cork Nat Univ Ie
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Publication date
Application filed by Entpr Ie Trd As Bioresearch Ie, Univ College Cork Nat Univ Ie filed Critical Entpr Ie Trd As Bioresearch Ie
Application granted granted Critical
Publication of ATE214104T1 publication Critical patent/ATE214104T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT98917568T 1998-04-22 1998-04-22 Verfahren zur charakterisierung von nukleinsäuremolekulen, das die erzeugung von verlängerbaren aufwärtsgelegenen dns-fragmenten, die durch spaltung der nukleinsäure an einer abasischen stelle entsteht, umfasst ATE214104T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/IE1998/000030 WO1999054501A1 (en) 1998-04-22 1998-04-22 A method for the characterisation of nucleic acid molecules involving generation of extendible upstream dna fragments resulting from the cleavage of nucleic acid at an abasic site

Publications (1)

Publication Number Publication Date
ATE214104T1 true ATE214104T1 (de) 2002-03-15

Family

ID=11042510

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98917568T ATE214104T1 (de) 1998-04-22 1998-04-22 Verfahren zur charakterisierung von nukleinsäuremolekulen, das die erzeugung von verlängerbaren aufwärtsgelegenen dns-fragmenten, die durch spaltung der nukleinsäure an einer abasischen stelle entsteht, umfasst

Country Status (14)

Country Link
US (1) US7175982B1 (de)
EP (1) EP1071811B8 (de)
JP (1) JP2002512044A (de)
CN (1) CN1198943C (de)
AT (1) ATE214104T1 (de)
AU (1) AU753661B2 (de)
CA (1) CA2325854C (de)
DE (1) DE69804143T2 (de)
DK (1) DK1071811T3 (de)
ES (1) ES2172887T3 (de)
NO (1) NO20005311L (de)
NZ (1) NZ508358A (de)
PT (1) PT1071811E (de)
WO (1) WO1999054501A1 (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2387035A1 (en) 1999-10-13 2001-04-19 Sequenom, Inc. Methods for generating databases and databases for identifying polymorphic genetic markers
US7668658B2 (en) 1999-10-13 2010-02-23 Sequenom, Inc. Methods for generating databases and databases for identifying polymorphic genetic markers
US6958214B2 (en) 2000-07-10 2005-10-25 Sequenom, Inc. Polymorphic kinase anchor proteins and nucleic acids encoding the same
IE20000887A1 (en) * 2000-11-03 2002-12-11 Univ College Cork Nat Univ Ie Method for the amplification and optional characterisation of nucleic acids
GB0126887D0 (en) 2001-11-08 2002-01-02 Univ London Method for producing and identifying soluble protein domains
US8030000B2 (en) 2002-02-21 2011-10-04 Alere San Diego, Inc. Recombinase polymerase amplification
US7270981B2 (en) 2002-02-21 2007-09-18 Asm Scientific, Inc. Recombinase polymerase amplification
US7399590B2 (en) 2002-02-21 2008-07-15 Asm Scientific, Inc. Recombinase polymerase amplification
JP4663988B2 (ja) * 2002-04-12 2011-04-06 ニュー・イングランド・バイオラブズ・インコーポレイティッド Ｄｎａ操作のための方法および組成物
WO2003093296A2 (en) 2002-05-03 2003-11-13 Sequenom, Inc. Kinase anchor protein muteins, peptides thereof, and related methods
IE20020544A1 (en) * 2002-06-28 2003-12-31 Univ College Cork Nat Univ Ie Method for the characterisation of nucleic acid molecules
EP1543154A4 (de) 2002-08-21 2006-08-16 Epoch Biosciences Inc Assay mit endonuklease für abasische stellen
AU2003298733B2 (en) 2002-11-27 2009-06-18 Agena Bioscience, Inc. Fragmentation-based methods and systems for sequence variation detection and discovery
WO2005014808A1 (ja) * 2003-06-30 2005-02-17 Matsushita Electric Industrial Co., Ltd. ヌクレオチド鎖修飾方法
WO2005065321A2 (en) 2003-12-29 2005-07-21 Nugen Technologies, Inc. Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids
US7608394B2 (en) 2004-03-26 2009-10-27 Sequenom, Inc. Methods and compositions for phenotype identification based on nucleic acid methylation
CA2561381C (en) 2004-03-26 2015-05-12 Sequenom, Inc. Base specific cleavage of methylation-specific amplification products in combination with mass analysis
JP2006271311A (ja) * 2005-03-30 2006-10-12 Hitachi Ltd 核酸分析方法
WO2007096702A2 (en) * 2005-07-25 2007-08-30 Asm Scientific, Inc. Methods for multiplexing recombinase polymerase amplification
US8071308B2 (en) 2006-05-04 2011-12-06 Alere San Diego, Inc. Recombinase polymerase amplification
CA2687218A1 (en) * 2007-05-14 2008-11-27 Insight Genetics, Inc. Methods of screening nucleic acids for single nucleotide variations
US20100285537A1 (en) * 2009-04-02 2010-11-11 Fluidigm Corporation Selective tagging of short nucleic acid fragments and selective protection of target sequences from degradation
JP5847076B2 (ja) 2009-05-20 2016-01-20 バイオサイト インコーポレイテッド Ｄｎａグリコシラーゼ／リアーゼおよびａｐエンドヌクレアーゼ基質
US8889353B2 (en) 2009-09-23 2014-11-18 Koninklijke Philips N.V. Method for monitoring the bisulfite-mediated conversion of DNA
CA3113672A1 (en) * 2011-07-01 2013-01-10 Htg Molecular Diagnostics, Inc. Methods of detecting gene fusions
WO2013059746A1 (en) 2011-10-19 2013-04-25 Nugen Technologies, Inc. Compositions and methods for directional nucleic acid amplification and sequencing
EP2807292B1 (de) 2012-01-26 2019-05-22 Tecan Genomics, Inc. Zusammensetzungen und verfahren zur gezielten nukleinsäuresequenzanreicherung und erzeugung einer hocheffizienten bibliothek
CA2877094A1 (en) 2012-06-18 2013-12-27 Nugen Technologies, Inc. Compositions and methods for negative selection of non-desired nucleic acid sequences
US20150011396A1 (en) 2012-07-09 2015-01-08 Benjamin G. Schroeder Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing
US9822408B2 (en) 2013-03-15 2017-11-21 Nugen Technologies, Inc. Sequential sequencing
WO2015073711A1 (en) 2013-11-13 2015-05-21 Nugen Technologies, Inc. Compositions and methods for identification of a duplicate sequencing read
US10266828B2 (en) 2013-12-16 2019-04-23 Syddansk Universitet RAS exon 2 skipping for cancer treatment
US9745614B2 (en) 2014-02-28 2017-08-29 Nugen Technologies, Inc. Reduced representation bisulfite sequencing with diversity adaptors
CA2957633A1 (en) 2014-08-06 2016-02-11 Nugen Technologies, Inc. Digital measurements from targeted sequencing
US12492430B2 (en) 2017-04-11 2025-12-09 Tecan Genomics, Inc. Library quantitation and qualification
US11099202B2 (en) 2017-10-20 2021-08-24 Tecan Genomics, Inc. Reagent delivery system
EP3851542A1 (de) 2020-01-20 2021-07-21 Tecan Genomics, Inc. Verarmung von reichlich uninformativen sequenzen
US12059674B2 (en) 2020-02-03 2024-08-13 Tecan Genomics, Inc. Reagent storage system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU5296496A (en) * 1995-03-24 1996-10-16 Mitokor Mutation detection by differential primer extension of mutant and wildtype target sequences
US5656430A (en) * 1995-06-07 1997-08-12 Trevigen, Inc. Oscillating signal amplifier for nucleic acid detection
ES2176358T3 (es) * 1995-07-11 2002-12-01 Forfas Trading As Biores Irela Deteccion mediada por glucosilasa de secuencias nucleotidicas conocidas.
US6190865B1 (en) 1995-09-27 2001-02-20 Epicentre Technologies Corporation Method for characterizing nucleic acid molecules

Also Published As

Publication number Publication date
DE69804143D1 (de) 2002-04-11
CN1291240A (zh) 2001-04-11
AU753661B2 (en) 2002-10-24
ES2172887T3 (es) 2002-10-01
DE69804143T2 (de) 2002-08-01
EP1071811B8 (de) 2003-01-02
EP1071811A1 (de) 2001-01-31
CA2325854A1 (en) 1999-10-28
CN1198943C (zh) 2005-04-27
WO1999054501A1 (en) 1999-10-28
CA2325854C (en) 2005-12-06
NO20005311D0 (no) 2000-10-20
JP2002512044A (ja) 2002-04-23
NZ508358A (en) 2002-07-26
NO20005311L (no) 2000-12-21
AU7075098A (en) 1999-11-08
DK1071811T3 (da) 2002-06-17
PT1071811E (pt) 2002-08-30
US7175982B1 (en) 2007-02-13
EP1071811B1 (de) 2002-03-06

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