ATE214104T1 - Verfahren zur charakterisierung von nukleinsäuremolekulen, das die erzeugung von verlängerbaren aufwärtsgelegenen dns-fragmenten, die durch spaltung der nukleinsäure an einer abasischen stelle entsteht, umfasst - Google Patents
Verfahren zur charakterisierung von nukleinsäuremolekulen, das die erzeugung von verlängerbaren aufwärtsgelegenen dns-fragmenten, die durch spaltung der nukleinsäure an einer abasischen stelle entsteht, umfasstInfo
- Publication number
- ATE214104T1 ATE214104T1 AT98917568T AT98917568T ATE214104T1 AT E214104 T1 ATE214104 T1 AT E214104T1 AT 98917568 T AT98917568 T AT 98917568T AT 98917568 T AT98917568 T AT 98917568T AT E214104 T1 ATE214104 T1 AT E214104T1
- Authority
- AT
- Austria
- Prior art keywords
- nucleic acid
- dna
- site
- cliving
- abase
- Prior art date
Links
- 239000012634 fragment Substances 0.000 title abstract 4
- 108020004707 nucleic acids Proteins 0.000 title abstract 4
- 102000039446 nucleic acids Human genes 0.000 title abstract 4
- 150000007523 nucleic acids Chemical class 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 2
- 108020004414 DNA Proteins 0.000 abstract 4
- 208000035657 Abasia Diseases 0.000 abstract 2
- 108020001738 DNA Glycosylase Proteins 0.000 abstract 2
- 102000028381 DNA glycosylase Human genes 0.000 abstract 2
- 238000011144 upstream manufacturing Methods 0.000 abstract 2
- 102000053602 DNA Human genes 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6827—Hybridisation assays for detection of mutation or polymorphism
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IE1998/000030 WO1999054501A1 (en) | 1998-04-22 | 1998-04-22 | A method for the characterisation of nucleic acid molecules involving generation of extendible upstream dna fragments resulting from the cleavage of nucleic acid at an abasic site |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE214104T1 true ATE214104T1 (de) | 2002-03-15 |
Family
ID=11042510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98917568T ATE214104T1 (de) | 1998-04-22 | 1998-04-22 | Verfahren zur charakterisierung von nukleinsäuremolekulen, das die erzeugung von verlängerbaren aufwärtsgelegenen dns-fragmenten, die durch spaltung der nukleinsäure an einer abasischen stelle entsteht, umfasst |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US7175982B1 (de) |
| EP (1) | EP1071811B8 (de) |
| JP (1) | JP2002512044A (de) |
| CN (1) | CN1198943C (de) |
| AT (1) | ATE214104T1 (de) |
| AU (1) | AU753661B2 (de) |
| CA (1) | CA2325854C (de) |
| DE (1) | DE69804143T2 (de) |
| DK (1) | DK1071811T3 (de) |
| ES (1) | ES2172887T3 (de) |
| NO (1) | NO20005311L (de) |
| NZ (1) | NZ508358A (de) |
| PT (1) | PT1071811E (de) |
| WO (1) | WO1999054501A1 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003519829A (ja) | 1999-10-13 | 2003-06-24 | シークエノム・インコーポレーテツド | データベースを作成する方法および多型遺伝的マーカーを同定するためのデータベース |
| US20030190644A1 (en) | 1999-10-13 | 2003-10-09 | Andreas Braun | Methods for generating databases and databases for identifying polymorphic genetic markers |
| US6958214B2 (en) | 2000-07-10 | 2005-10-25 | Sequenom, Inc. | Polymorphic kinase anchor proteins and nucleic acids encoding the same |
| IE20000887A1 (en) * | 2000-11-03 | 2002-12-11 | Univ College Cork Nat Univ Ie | Method for the amplification and optional characterisation of nucleic acids |
| GB0126887D0 (en) * | 2001-11-08 | 2002-01-02 | Univ London | Method for producing and identifying soluble protein domains |
| CA2476481C (en) | 2002-02-21 | 2016-01-26 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| US7399590B2 (en) | 2002-02-21 | 2008-07-15 | Asm Scientific, Inc. | Recombinase polymerase amplification |
| US8030000B2 (en) | 2002-02-21 | 2011-10-04 | Alere San Diego, Inc. | Recombinase polymerase amplification |
| US7435572B2 (en) * | 2002-04-12 | 2008-10-14 | New England Biolabs, Inc. | Methods and compositions for DNA manipulation |
| US7432342B2 (en) | 2002-05-03 | 2008-10-07 | Sequenom, Inc. | Kinase anchor protein muteins, peptides thereof and related documents |
| IE20020544A1 (en) * | 2002-06-28 | 2003-12-31 | Univ College Cork Nat Univ Ie | Method for the characterisation of nucleic acid molecules |
| CA2494993A1 (en) | 2002-08-21 | 2004-03-04 | Epoch Biosciences, Inc. | Abasic site endonuclease assay |
| CA2507189C (en) | 2002-11-27 | 2018-06-12 | Sequenom, Inc. | Fragmentation-based methods and systems for sequence variation detection and discovery |
| KR100683025B1 (ko) * | 2003-06-30 | 2007-02-15 | 마츠시타 덴끼 산교 가부시키가이샤 | 뉴클레오티드쇄 수식방법 |
| CA2552007A1 (en) | 2003-12-29 | 2005-07-21 | Nugen Technologies, Inc. | Methods for analysis of nucleic acid methylation status and methods for fragmentation, labeling and immobilization of nucleic acids |
| US7608394B2 (en) | 2004-03-26 | 2009-10-27 | Sequenom, Inc. | Methods and compositions for phenotype identification based on nucleic acid methylation |
| US9249456B2 (en) | 2004-03-26 | 2016-02-02 | Agena Bioscience, Inc. | Base specific cleavage of methylation-specific amplification products in combination with mass analysis |
| JP2006271311A (ja) * | 2005-03-30 | 2006-10-12 | Hitachi Ltd | 核酸分析方法 |
| EP1929049B1 (de) * | 2005-07-25 | 2013-04-10 | Alere San Diego, Inc. | Verfahren zur multiplexierung einer rekombinase-polymerase-verstärkung |
| JP2009535053A (ja) | 2006-05-04 | 2009-10-01 | エーエスエム サイエンティフィック， インコーポレイテッド | レコンビナーゼポリメラーゼ増幅 |
| EP2152915A2 (de) * | 2007-05-14 | 2010-02-17 | Insight Genetics, Inc. | Verfahren zum screening von nukleinsäuren auf einzelnukleotidvariationen |
| US20100285537A1 (en) * | 2009-04-02 | 2010-11-11 | Fluidigm Corporation | Selective tagging of short nucleic acid fragments and selective protection of target sequences from degradation |
| US9469867B2 (en) | 2009-05-20 | 2016-10-18 | Alere San Diego, Inc. | DNA glycosylase/lyase and AP endonuclease substrates |
| EP2480685B1 (de) | 2009-09-23 | 2013-08-28 | Koninklijke Philips Electronics N.V. | Verfahren zur überwachung der bisulfitvermittelten umwandlung von dna |
| AU2011372509B2 (en) * | 2011-07-01 | 2017-02-09 | Htg Molecular Diagnostics, Inc. | Methods of detecting gene fusions |
| SG10201510189WA (en) | 2011-10-19 | 2016-01-28 | Nugen Technologies Inc | Compositions And Methods For Directional Nucleic Acid Amplification And Sequencing |
| SG11201404243WA (en) | 2012-01-26 | 2014-08-28 | Nugen Technologies Inc | Compositions and methods for targeted nucleic acid sequence enrichment and high efficiency library generation |
| JP6181751B2 (ja) | 2012-06-18 | 2017-08-16 | ニューゲン テクノロジーズ， インコーポレイテッド | 望まれない核酸配列のネガティブ選択のための組成物および方法 |
| US20150011396A1 (en) | 2012-07-09 | 2015-01-08 | Benjamin G. Schroeder | Methods for creating directional bisulfite-converted nucleic acid libraries for next generation sequencing |
| WO2014144092A1 (en) | 2013-03-15 | 2014-09-18 | Nugen Technologies, Inc. | Sequential sequencing |
| CA2929596C (en) | 2013-11-13 | 2022-07-05 | Nugen Technologies, Inc. | Compositions and methods for identification of a duplicate sequencing read |
| US10266828B2 (en) | 2013-12-16 | 2019-04-23 | Syddansk Universitet | RAS exon 2 skipping for cancer treatment |
| US9745614B2 (en) | 2014-02-28 | 2017-08-29 | Nugen Technologies, Inc. | Reduced representation bisulfite sequencing with diversity adaptors |
| CN107075581B (zh) | 2014-08-06 | 2022-03-18 | 纽亘技术公司 | 由靶向测序进行数字测量 |
| US12492430B2 (en) | 2017-04-11 | 2025-12-09 | Tecan Genomics, Inc. | Library quantitation and qualification |
| US11099202B2 (en) | 2017-10-20 | 2021-08-24 | Tecan Genomics, Inc. | Reagent delivery system |
| EP3851542A1 (de) | 2020-01-20 | 2021-07-21 | Tecan Genomics, Inc. | Verarmung von reichlich uninformativen sequenzen |
| CN113275053A (zh) | 2020-02-03 | 2021-08-20 | 帝肯基因组学公司 | 试剂存储系统 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996030545A1 (en) * | 1995-03-24 | 1996-10-03 | Mitokor | Mutation detection by differential primer extension of mutant and wildtype target sequences |
| US5656430A (en) * | 1995-06-07 | 1997-08-12 | Trevigen, Inc. | Oscillating signal amplifier for nucleic acid detection |
| JP3790797B2 (ja) | 1995-07-11 | 2006-06-28 | フォーファス | グリコシラーゼによる候補座位のヌクレオチド配列の検出 |
| US6190865B1 (en) | 1995-09-27 | 2001-02-20 | Epicentre Technologies Corporation | Method for characterizing nucleic acid molecules |
-
1998
- 1998-04-22 AT AT98917568T patent/ATE214104T1/de not_active IP Right Cessation
- 1998-04-22 PT PT98917568T patent/PT1071811E/pt unknown
- 1998-04-22 WO PCT/IE1998/000030 patent/WO1999054501A1/en not_active Ceased
- 1998-04-22 CA CA002325854A patent/CA2325854C/en not_active Expired - Fee Related
- 1998-04-22 AU AU70750/98A patent/AU753661B2/en not_active Ceased
- 1998-04-22 NZ NZ508358A patent/NZ508358A/en unknown
- 1998-04-22 US US09/673,739 patent/US7175982B1/en not_active Expired - Fee Related
- 1998-04-22 ES ES98917568T patent/ES2172887T3/es not_active Expired - Lifetime
- 1998-04-22 DK DK98917568T patent/DK1071811T3/da active
- 1998-04-22 DE DE69804143T patent/DE69804143T2/de not_active Expired - Fee Related
- 1998-04-22 JP JP2000544829A patent/JP2002512044A/ja active Pending
- 1998-04-22 EP EP98917568A patent/EP1071811B8/de not_active Expired - Lifetime
- 1998-04-22 CN CNB988139812A patent/CN1198943C/zh not_active Expired - Fee Related
-
2000
- 2000-10-20 NO NO20005311A patent/NO20005311L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DE69804143T2 (de) | 2002-08-01 |
| US7175982B1 (en) | 2007-02-13 |
| DK1071811T3 (da) | 2002-06-17 |
| NO20005311D0 (no) | 2000-10-20 |
| EP1071811B1 (de) | 2002-03-06 |
| WO1999054501A1 (en) | 1999-10-28 |
| ES2172887T3 (es) | 2002-10-01 |
| PT1071811E (pt) | 2002-08-30 |
| DE69804143D1 (de) | 2002-04-11 |
| AU7075098A (en) | 1999-11-08 |
| JP2002512044A (ja) | 2002-04-23 |
| CA2325854A1 (en) | 1999-10-28 |
| CA2325854C (en) | 2005-12-06 |
| AU753661B2 (en) | 2002-10-24 |
| CN1291240A (zh) | 2001-04-11 |
| EP1071811B8 (de) | 2003-01-02 |
| NZ508358A (en) | 2002-07-26 |
| NO20005311L (no) | 2000-12-21 |
| EP1071811A1 (de) | 2001-01-31 |
| CN1198943C (zh) | 2005-04-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |