ATE222759T1 - Tranilast enthaltendes externum und verfahren zu dessen herstellung - Google Patents

Tranilast enthaltendes externum und verfahren zu dessen herstellung

Info

Publication number
ATE222759T1
ATE222759T1 AT97902588T AT97902588T ATE222759T1 AT E222759 T1 ATE222759 T1 AT E222759T1 AT 97902588 T AT97902588 T AT 97902588T AT 97902588 T AT97902588 T AT 97902588T AT E222759 T1 ATE222759 T1 AT E222759T1
Authority
AT
Austria
Prior art keywords
tranilast
active ingredient
aqueous base
externum
producing
Prior art date
Application number
AT97902588T
Other languages
English (en)
Inventor
Masao Mori
Noriyasu Saito
Original Assignee
Lead Chem Co Ltd
Kissei Pharmaceutical
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lead Chem Co Ltd, Kissei Pharmaceutical filed Critical Lead Chem Co Ltd
Application granted granted Critical
Publication of ATE222759T1 publication Critical patent/ATE222759T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT97902588T 1996-02-07 1997-02-06 Tranilast enthaltendes externum und verfahren zu dessen herstellung ATE222759T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4549396 1996-02-07
PCT/JP1997/000283 WO1997028793A1 (fr) 1996-02-07 1997-02-06 Preparation a usage externe comprenant du tranilast et processus de production de cette preparation

Publications (1)

Publication Number Publication Date
ATE222759T1 true ATE222759T1 (de) 2002-09-15

Family

ID=12720933

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97902588T ATE222759T1 (de) 1996-02-07 1997-02-06 Tranilast enthaltendes externum und verfahren zu dessen herstellung

Country Status (11)

Country Link
US (1) US6239177B1 (de)
EP (1) EP0974350B1 (de)
JP (1) JP4154621B2 (de)
KR (1) KR100449939B1 (de)
CN (1) CN1081030C (de)
AT (1) ATE222759T1 (de)
DE (2) DE69715049T2 (de)
DK (1) DK0974350T3 (de)
ES (1) ES2151464T3 (de)
PT (1) PT974350E (de)
WO (1) WO1997028793A1 (de)

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KR19990082523A (ko) * 1996-02-15 1999-11-25 간자와 무츠와 혈관생성 억제제
JP4865958B2 (ja) * 2001-05-23 2012-02-01 株式会社トクホン 鎮痛抗炎症局所作用型の貼付剤
WO2004041270A1 (ja) * 2002-11-05 2004-05-21 Lead Chemical Co.,Ltd. ３−メチル−１−フェニル−２−ピラゾリン−５−オン含有経皮吸収製剤
JP2004307364A (ja) * 2003-04-03 2004-11-04 Yuutoku Yakuhin Kogyo Kk 経皮吸収貼付剤
AU2003280739A1 (en) * 2003-11-12 2004-06-06 Lead Chemical Co., Ltd. Percutaneous absorption type cerebral protective agent
US9066912B2 (en) * 2003-11-17 2015-06-30 Ethicon, Inc. Drug-enhanced adhesion prevention
US20050106230A1 (en) * 2003-11-17 2005-05-19 Young Janel E. Drug-enhanced adhesion prevention
US20050239892A1 (en) * 2003-11-21 2005-10-27 Trustees Of Tufts College Therapeutic avenathramide compounds
US7105263B2 (en) * 2003-12-30 2006-09-12 Samsung Electronics Company Dry toner comprising encapsulated pigment, methods and uses
JP4590224B2 (ja) * 2004-07-20 2010-12-01 株式会社日本点眼薬研究所 トラニラストまたは薬理学的に許容される塩を含有する懸濁性医薬組成物
JP4843824B2 (ja) 2004-08-18 2011-12-21 株式会社 メドレックス 外用剤
US7473738B2 (en) * 2004-09-30 2009-01-06 Johnson & Johnson Vision Care, Inc. Lactam polymer derivatives
US20080009519A1 (en) * 2004-11-17 2008-01-10 Lawrence Steinman Method of modulating t cell functioning
US20100041756A1 (en) * 2004-11-17 2010-02-18 Michael Lionel Selley method of modulating b cell functioning
JP2007051089A (ja) * 2005-08-18 2007-03-01 Medorekkusu:Kk 外用剤
WO2007046544A1 (ja) * 2005-10-21 2007-04-26 Medrx Co., Ltd. カルボキシル基を有する肥満細胞脱顆粒抑制剤と有機アミンとの塩を含有する外用剤
JP4959991B2 (ja) * 2006-03-03 2012-06-27 株式会社日本点眼薬研究所 トラニラストまたはその薬理学的に許容される塩を含有する懸濁性医薬組成物
MX352516B (es) 2006-07-05 2017-04-06 Fibrotech Therapeutics Pty Ltd Compuestos terapeuticos.
US8883190B2 (en) * 2006-12-01 2014-11-11 Wake Forest University Health Sciences Urologic devices incorporating collagen inhibitors
EP2030617A1 (de) * 2007-08-17 2009-03-04 Sygnis Bioscience GmbH & Co. KG Verwendungen von Tranilast und Derivaten daraus zur Behandlung neurologischer Leiden
CN101152164B (zh) * 2007-09-14 2011-04-06 李世荣 含有抗肥大细胞类药物的抗瘢痕外用贴膜及其制备方法
CN101152163B (zh) * 2007-09-14 2010-05-26 李世荣 含有激素类药物的抗瘢痕外用贴膜及其制备方法
CN102574843B (zh) 2009-10-22 2015-06-17 法博太科制药有限公司 抗纤维化剂的稠环类似物
WO2012176668A1 (ja) * 2011-06-20 2012-12-27 久光製薬株式会社 リドカイン含有パップ剤
JP6096021B2 (ja) * 2013-03-22 2017-03-15 ファイテン株式会社 顎関節症用外用剤
JP6558117B2 (ja) * 2014-08-19 2019-08-14 大正製薬株式会社 皮膚用剤
MA41266A (fr) * 2014-12-22 2017-10-31 Hisamitsu Pharmaceutical Co Cataplasme
WO2016136556A1 (ja) 2015-02-24 2016-09-01 久光製薬株式会社 パップ剤
CN104784101A (zh) * 2015-03-05 2015-07-22 中国药科大学制药有限公司 一种曲尼司特凝胶和软膏剂的处方及制备方法
KR101691472B1 (ko) 2015-07-06 2017-01-09 이광재 배낭에 탈착이 용이한 스틱 걸이
CN109843286A (zh) * 2016-08-23 2019-06-04 纽里姆药物有限公司 治疗瘙痒和/或搔痒的方法
JP7185631B2 (ja) 2017-02-03 2022-12-07 サータ セラピューティクス プロプライエタリー リミテッド 抗線維化化合物
CN108324724A (zh) * 2018-04-10 2018-07-27 苏州芝宇生物科技有限公司 一种克立硼罗可溶性膜制剂的制法及其应用
BR112021015884A2 (pt) 2019-02-14 2021-10-05 Hisamitsu Pharmaceutical Co., Inc. Cataplasma

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JPS62169723A (ja) * 1986-01-22 1987-07-25 Teisan Seiyaku Kk 徐放化製剤
JPS63238024A (ja) * 1987-03-26 1988-10-04 Towa Yakuhin Kk 水難溶性薬物を含有する外用ゲル組成物
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US5719197A (en) * 1988-03-04 1998-02-17 Noven Pharmaceuticals, Inc. Compositions and methods for topical administration of pharmaceutically active agents
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Also Published As

Publication number Publication date
EP0974350A4 (de) 2000-01-26
HK1018218A1 (en) 1999-12-17
EP0974350B1 (de) 2002-08-28
US6239177B1 (en) 2001-05-29
KR19990082254A (ko) 1999-11-25
DE69715049D1 (de) 2002-10-02
ES2151464T1 (es) 2001-01-01
CN1081030C (zh) 2002-03-20
JP4154621B2 (ja) 2008-09-24
CN1210462A (zh) 1999-03-10
ES2151464T3 (es) 2002-12-16
DE69715049T2 (de) 2003-04-03
DE974350T1 (de) 2001-01-25
WO1997028793A1 (fr) 1997-08-14
EP0974350A1 (de) 2000-01-26
DK0974350T3 (da) 2002-11-25
KR100449939B1 (ko) 2004-11-20
PT974350E (pt) 2002-12-31

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee