ATE235483T1 - Neue chalchone - Google Patents

Neue chalchone

Info

Publication number
ATE235483T1
ATE235483T1 AT00964042T AT00964042T ATE235483T1 AT E235483 T1 ATE235483 T1 AT E235483T1 AT 00964042 T AT00964042 T AT 00964042T AT 00964042 T AT00964042 T AT 00964042T AT E235483 T1 ATE235483 T1 AT E235483T1
Authority
AT
Austria
Prior art keywords
chalchone
new
medicament
prevention
manufacture
Prior art date
Application number
AT00964042T
Other languages
English (en)
Inventor
Ezio Bombardelli
Piero Valenti
Original Assignee
Indena Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Indena Spa filed Critical Indena Spa
Application granted granted Critical
Publication of ATE235483T1 publication Critical patent/ATE235483T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/28—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only
    • C07D311/30—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 2 only not hydrogenated in the hetero ring, e.g. flavones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/78—Ring systems having three or more relevant rings
    • C07D311/80—Dibenzopyrans; Hydrogenated dibenzopyrans
    • C07D311/82—Xanthenes
    • C07D311/84—Xanthenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 9
    • C07D311/86—Oxygen atoms, e.g. xanthones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT00964042T 1999-09-03 2000-08-28 Neue chalchone ATE235483T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9920910.8A GB9920910D0 (en) 1999-09-03 1999-09-03 Novel chalcones
PCT/EP2000/008366 WO2001017988A1 (en) 1999-09-03 2000-08-28 Novel chalcones

Publications (1)

Publication Number Publication Date
ATE235483T1 true ATE235483T1 (de) 2003-04-15

Family

ID=10860346

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00964042T ATE235483T1 (de) 1999-09-03 2000-08-28 Neue chalchone

Country Status (21)

Country Link
US (1) US6620842B2 (de)
EP (1) EP1212315B1 (de)
JP (1) JP2003508527A (de)
KR (1) KR100819576B1 (de)
CN (1) CN1177843C (de)
AT (1) ATE235483T1 (de)
AU (1) AU776226B2 (de)
CA (1) CA2382130A1 (de)
CZ (1) CZ2002787A3 (de)
DE (1) DE60001851T2 (de)
DK (1) DK1212315T3 (de)
ES (1) ES2193106T3 (de)
GB (1) GB9920910D0 (de)
HK (1) HK1043999B (de)
HU (1) HUP0202579A3 (de)
NO (1) NO20021049L (de)
PL (1) PL353064A1 (de)
PT (1) PT1212315E (de)
RU (1) RU2252938C2 (de)
SK (1) SK3112002A3 (de)
WO (1) WO2001017988A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60333094D1 (de) 2002-04-17 2010-08-05 Cytokinetics Inc Verbindungen, zusammensetzungen und verfahren
US7638554B2 (en) * 2002-04-18 2009-12-29 Sri International Flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
US20030229136A1 (en) * 2002-04-18 2003-12-11 Nurulain Zaveri Novel flavanoids as chemotherapeutic, chemopreventive, and antiangiogenic agents
EP1539727B1 (de) 2002-07-17 2009-02-18 Cytokinetics, Inc. Verbindungen, zusammensetzungen und verfahren zur behandlung von zellulären proliferativen erkrankungen
US6864264B1 (en) * 2002-08-20 2005-03-08 Gloria L. Anderson 1-adamantyl chalcones for the treatment of proliferative disorders
CN100336797C (zh) * 2005-08-19 2007-09-12 浙江大学 四取代查耳酮衍生物及制备方法和用途
CN104169267B (zh) * 2012-03-01 2017-03-01 香港理工大学 含炔烃的类黄酮、含叠氮化物的类黄酮和含三唑的类黄酮作为调节剂用于癌症的多药耐药

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT58310A (en) * 1988-12-21 1992-02-28 Upjohn Co Anti-atherosclerotic and anti-thrombotic 1-benzopyran-4-one- and 2-amino-1,3-benzoxazin-4-one derivatives, process for producing them and pharmaceutical compositions containing them
US5023341A (en) * 1989-09-19 1991-06-11 Allergan, Inc. Compounds having a disubstituted acetylene moiety and retinoic acid-like biological activity
US4996230A (en) * 1990-02-16 1991-02-26 Eli Lilly And Company Leukotriene antagonists
AU7963691A (en) * 1990-05-17 1991-12-10 Baylor College Of Medicine Growth inhibitors and methods of treating cancer and cell proliferative diseases
IT1271301B (it) * 1994-12-20 1997-05-27 Indena Spa Calconi naturali e sintetici e loro esteri ad attivita' antiproliferativa nei tumori dell'utero,dell'ovaio e del seno e formulazioni che li contengono
US5525625A (en) * 1995-01-24 1996-06-11 Warner-Lambert Company 2-(2-Amino-3-methoxyphenyl)-4-oxo-4H-[1]benzopyran for treating proliferative disorders

Also Published As

Publication number Publication date
US20030055056A1 (en) 2003-03-20
KR100819576B1 (ko) 2008-04-22
EP1212315B1 (de) 2003-03-26
HUP0202579A3 (en) 2003-07-28
US6620842B2 (en) 2003-09-16
EP1212315A1 (de) 2002-06-12
DE60001851T2 (de) 2003-12-11
CN1371372A (zh) 2002-09-25
GB9920910D0 (en) 1999-11-10
RU2252938C2 (ru) 2005-05-27
HK1043999A1 (en) 2002-10-04
CN1177843C (zh) 2004-12-01
KR20020031598A (ko) 2002-05-02
DE60001851D1 (de) 2003-04-30
SK3112002A3 (en) 2003-10-07
AU7510900A (en) 2001-04-10
AU776226B2 (en) 2004-09-02
NO20021049L (no) 2002-05-03
HK1043999B (en) 2003-08-15
DK1212315T3 (da) 2003-06-23
CA2382130A1 (en) 2001-03-15
ES2193106T3 (es) 2003-11-01
NO20021049D0 (no) 2002-03-01
PL353064A1 (en) 2003-10-06
JP2003508527A (ja) 2003-03-04
HUP0202579A2 (hu) 2002-11-28
CZ2002787A3 (cs) 2002-06-12
PT1212315E (pt) 2003-08-29
WO2001017988A1 (en) 2001-03-15

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