ATE246200T1 - Dem menschlichen gewebefaktor ähnliche dns- segmente, polypeptide und antikörper - Google Patents

Dem menschlichen gewebefaktor ähnliche dns- segmente, polypeptide und antikörper

Info

Publication number
ATE246200T1
ATE246200T1 AT88903654T AT88903654T ATE246200T1 AT E246200 T1 ATE246200 T1 AT E246200T1 AT 88903654 T AT88903654 T AT 88903654T AT 88903654 T AT88903654 T AT 88903654T AT E246200 T1 ATE246200 T1 AT E246200T1
Authority
AT
Austria
Prior art keywords
human tissue
tissue factor
dna segments
antibodies
polypeptides
Prior art date
Application number
AT88903654T
Other languages
English (en)
Inventor
Thomas S Edgington
James H Morrissey
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27364291&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE246200(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US07/067,103 external-priority patent/US5110730A/en
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE246200T1 publication Critical patent/ATE246200T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/36—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
    • Y10S530/809—Fused cells, e.g. hybridoma

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT88903654T 1987-03-31 1988-03-29 Dem menschlichen gewebefaktor ähnliche dns- segmente, polypeptide und antikörper ATE246200T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3304787A 1987-03-31 1987-03-31
US07/067,103 US5110730A (en) 1987-03-31 1987-06-25 Human tissue factor related DNA segments
US07/165,939 US5223427A (en) 1987-03-31 1988-03-09 Hybridomas producing monoclonal antibodies reactive with human tissue-factor glycoprotein heavy chain
PCT/US1988/000998 WO1988007543A1 (en) 1987-03-31 1988-03-29 Human tissue factor related dna segments, polypeptides and antibodies

Publications (1)

Publication Number Publication Date
ATE246200T1 true ATE246200T1 (de) 2003-08-15

Family

ID=27364291

Family Applications (1)

Application Number Title Priority Date Filing Date
AT88903654T ATE246200T1 (de) 1987-03-31 1988-03-29 Dem menschlichen gewebefaktor ähnliche dns- segmente, polypeptide und antikörper

Country Status (13)

Country Link
US (2) US5223427A (de)
EP (2) EP0309548B1 (de)
JP (1) JP2809415B2 (de)
AT (1) ATE246200T1 (de)
AU (1) AU605864B2 (de)
CA (1) CA1340544C (de)
DE (1) DE3856560T2 (de)
DK (1) DK175703B1 (de)
ES (1) ES2009590A6 (de)
FI (2) FI100184B (de)
NO (1) NO305211B1 (de)
PT (1) PT87138B (de)
WO (1) WO1988007543A1 (de)

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US5374617A (en) * 1992-05-13 1994-12-20 Oklahoma Medical Research Foundation Treatment of bleeding with modified tissue factor in combination with FVIIa
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EP0833911B1 (de) * 1995-06-07 2004-05-12 Ortho Pharmaceutical Corporation Cdr-transplantierte antikörper gegen "tissue factor" und verfahren zur deren verwendung
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
US6132729A (en) 1997-01-22 2000-10-17 Board Of Regents, The University Of Texas System Combined tissue factor and chemotherapeutic methods and compositions for coagulation and tumor treatment
US5986065A (en) * 1997-03-10 1999-11-16 Sunol Molecular Corporation Antibodies for inhibiting blood coagulation and methods of use thereof
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US6818213B1 (en) 1998-07-13 2004-11-16 Board Of Regents, The University Of Texas System Cancer treatment compositions comprising therapeutic conjugates that bind to aminophospholipids
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JP6055404B2 (ja) * 2010-06-15 2016-12-27 ゲンマブ エー／エス 組織因子に対するヒト抗体薬物結合体
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KR102945203B1 (ko) 2017-05-08 2026-03-31 시애틀 프로젝트 코포레이션 알파바이러스 신생항원 벡터
KR101989954B1 (ko) * 2017-10-16 2019-06-17 고려대학교 산학협력단 돼지 조직인자 세포외 도메인 단백질을 특이적으로 인식하는 단일클론항체 및 이의 용도
KR20240134250A (ko) * 2018-01-04 2024-09-06 아이코닉 테라퓨틱스, 인코포레이티드 항-조직 인자 항체, 항체-약물 결합체, 및 관련 방법
TWI841554B (zh) 2018-03-21 2024-05-11 丹麥商珍美寶股份有限公司 以鉑為主之劑與抗組織因子抗體－藥物共軛物的組合治療癌症之方法
JP7460608B2 (ja) 2018-05-07 2024-04-02 ジェンマブ エー／エス 抗ｐｄ－１抗体と抗組織因子抗体－薬物コンジュゲートとの組み合わせを用いるがんの治療方法
TWI844571B (zh) 2018-10-30 2024-06-11 丹麥商珍美寶股份有限公司 使用抗血管內皮生長因子（ｖｅｇｆ）抗體與抗組織因子（ｔｆ）抗體－藥物共軛體之組合以治療癌症之方法
KR20210090650A (ko) 2018-11-07 2021-07-20 그릿스톤 바이오, 인코포레이티드 알파바이러스 신생항원 벡터 및 인터페론 억제제
SG11202113187WA (en) 2019-05-30 2021-12-30 Gritstone Bio Inc Modified adenoviruses
IL300026A (en) 2020-08-06 2023-03-01 Gritstone Bio Inc Multiepitope vaccine cassettes

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IE81149B1 (en) * 1987-02-12 2000-05-03 Genentech Inc Methods and deoxyribonucleic acid for the preparation of tissue factor protein
EP0321526A1 (de) * 1987-06-12 1989-06-28 Mount Sinai School Of Medicine Of The City University Of New York Klonierung und expression von humanem gewebefaktor

Also Published As

Publication number Publication date
AU1627488A (en) 1988-11-02
EP0309548A1 (de) 1989-04-05
PT87138B (pt) 1992-07-31
WO1988007543A1 (en) 1988-10-06
PT87138A (pt) 1988-04-01
EP0309548A4 (en) 1991-08-07
FI885543A0 (fi) 1988-11-29
EP0309548B1 (de) 2003-07-30
DK666888A (da) 1989-01-31
DE3856560T2 (de) 2004-08-05
DK175703B1 (da) 2005-01-24
NO305211B1 (no) 1999-04-19
DK666888D0 (da) 1988-11-29
US5223427A (en) 1993-06-29
FI97813C (fi) 1997-02-25
DE3856560D1 (de) 2003-09-04
FI885543L (fi) 1988-11-29
JPH01503438A (ja) 1989-11-22
AU605864B2 (en) 1991-01-24
EP1364969A3 (de) 2004-12-29
NO885326L (no) 1989-01-30
EP1364969A2 (de) 2003-11-26
NO885326D0 (no) 1988-11-29
JP2809415B2 (ja) 1998-10-08
ES2009590A6 (es) 1989-10-01
CA1340544C (en) 1999-05-18
FI97813B (fi) 1996-11-15
US5622931A (en) 1997-04-22
FI954347A0 (fi) 1995-09-15
FI954347L (fi) 1995-09-15
FI100184B (fi) 1997-10-15

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