ATE250050T1 - Kristalline base von citalopram, und hydrochlorid-oder hydrobromidsalz davon - Google Patents

Kristalline base von citalopram, und hydrochlorid-oder hydrobromidsalz davon

Info

Publication number
ATE250050T1
ATE250050T1 AT02009350T AT02009350T ATE250050T1 AT E250050 T1 ATE250050 T1 AT E250050T1 AT 02009350 T AT02009350 T AT 02009350T AT 02009350 T AT02009350 T AT 02009350T AT E250050 T1 ATE250050 T1 AT E250050T1
Authority
AT
Austria
Prior art keywords
citalopram
hydrochloride
hydrobromide salt
crystalline base
crystalline
Prior art date
Application number
AT02009350T
Other languages
English (en)
Inventor
Hans Petersen
Klaus Peter Boegesoe
Per Holm
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8159320&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE250050(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of ATE250050T1 publication Critical patent/ATE250050T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Laminated Bodies (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Manufacture Of Macromolecular Shaped Articles (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT02009350T 2000-03-13 2001-02-28 Kristalline base von citalopram, und hydrochlorid-oder hydrobromidsalz davon ATE250050T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200000402 2000-03-13
DKPCT/DK00/00183 2000-04-13

Publications (1)

Publication Number Publication Date
ATE250050T1 true ATE250050T1 (de) 2003-10-15

Family

ID=8159320

Family Applications (3)

Application Number Title Priority Date Filing Date
AT01909568T ATE223396T1 (de) 2000-03-13 2001-02-28 Kristalline base des citaloprams
AT02009350T ATE250050T1 (de) 2000-03-13 2001-02-28 Kristalline base von citalopram, und hydrochlorid-oder hydrobromidsalz davon
AT0016601U AT4364U1 (de) 2000-03-13 2001-03-07 Kristalline citalopram-base

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT01909568T ATE223396T1 (de) 2000-03-13 2001-02-28 Kristalline base des citaloprams

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT0016601U AT4364U1 (de) 2000-03-13 2001-03-07 Kristalline citalopram-base

Country Status (41)

Country Link
US (7) US20010031784A1 (de)
EP (2) EP1169314B2 (de)
JP (1) JP2003527383A (de)
KR (1) KR20020080486A (de)
CN (2) CN1258530C (de)
AR (1) AR029811A1 (de)
AT (3) ATE223396T1 (de)
AU (2) AU746664B2 (de)
BE (1) BE1013210A3 (de)
BG (1) BG107065A (de)
BR (1) BR0109373A (de)
CA (2) CA2411732A1 (de)
CH (2) CH691477A5 (de)
CZ (1) CZ292077B6 (de)
DE (7) DE20007303U1 (de)
DK (3) DK173903B1 (de)
EA (1) EA200200972A1 (de)
ES (3) ES2180471T3 (de)
FI (2) FI20010156A0 (de)
FR (1) FR2806086B1 (de)
GB (2) GB2357762B (de)
GR (1) GR1003796B (de)
HR (1) HRP20020756A2 (de)
HU (3) HU0001581D0 (de)
IE (1) IES20010109A2 (de)
IL (2) IL147339A (de)
IS (1) IS5841A (de)
IT (2) IT1319645B1 (de)
MX (1) MXPA02008793A (de)
NL (2) NL1016435C1 (de)
NO (2) NO312031B1 (de)
PL (1) PL360158A1 (de)
PT (2) PT1169314E (de)
SE (2) SE517136C2 (de)
SI (2) SI1227088T1 (de)
SK (1) SK285528B6 (de)
TR (1) TR200202185T2 (de)
UA (1) UA74360C2 (de)
WO (1) WO2001068627A1 (de)
YU (1) YU68802A (de)
ZA (1) ZA200207148B (de)

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US7713279B2 (en) 2000-12-20 2010-05-11 Fox Hollow Technologies, Inc. Method and devices for cutting tissue
US7708749B2 (en) 2000-12-20 2010-05-04 Fox Hollow Technologies, Inc. Debulking catheters and methods
US8328829B2 (en) 1999-08-19 2012-12-11 Covidien Lp High capacity debulking catheter with razor edge cutting window
US7887556B2 (en) 2000-12-20 2011-02-15 Fox Hollow Technologies, Inc. Debulking catheters and methods
US6299622B1 (en) 1999-08-19 2001-10-09 Fox Hollow Technologies, Inc. Atherectomy catheter with aligned imager
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
GB2357762B (en) * 2000-03-13 2002-01-30 Lundbeck & Co As H Crystalline base of citalopram
US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof
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GB2376233B (en) * 2000-08-10 2003-09-10 Lundbeck & Co As H Crystals of a pharmaceutically acceptable salt of citalopram wherein the median size of the crystals is at least 40 microns
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GB2387844B (en) * 2002-02-27 2005-05-11 Matrix Lab Ltd Separation of impurities from a crude mixture of citalopram
GB2386118A (en) * 2002-02-27 2003-09-10 Cipla Ltd Citalopram
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
GB0204607D0 (en) 2002-02-27 2002-04-10 Matrix Lab Ltd Process
GB2385848A (en) * 2002-02-27 2003-09-03 Cipla Ltd Citalopram salts
EP1346989A1 (de) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Verbessertes Verfahren zur Herstellung von Citalopram und Citalopram Hydrobromid
GB0206708D0 (en) * 2002-03-21 2002-05-01 Cipla Ltd Pharmaceutical salts
US6812355B2 (en) 2002-10-22 2004-11-02 Sekhsaria Chemicals Limited Process for the manufacture of citalopram hydrobromide from 5-bromophthalide
TR200504022T1 (tr) * 2003-03-24 2006-08-21 Hetero Drugs Limited (S)-sitalopram oksalatın yeni sıvı kristal formları.
WO2004094399A1 (en) * 2003-04-21 2004-11-04 Natco Pharma Ltd An improved process for the preparation of citalopram hydrobromide
US8246640B2 (en) 2003-04-22 2012-08-21 Tyco Healthcare Group Lp Methods and devices for cutting tissue at a vascular location
US7019153B2 (en) 2003-06-10 2006-03-28 Sun Pharmaceutical Industries Limited Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
GB0317475D0 (en) * 2003-07-25 2003-08-27 Meditab Specialities Pvt Ltd Product
JP4025735B2 (ja) * 2003-08-21 2007-12-26 ローム アンド ハース カンパニー 水性系を処理する方法
GB0320312D0 (en) 2003-08-29 2003-10-01 Novartis Ag Purification process
CN100569765C (zh) * 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
ITTO20050301A1 (it) * 2005-05-05 2006-11-06 Errekappa Euroterapici Spa Formulazioni liquide orali contenenti citalopram
US20110196032A1 (en) * 2005-05-20 2011-08-11 Ashish Gogia Pharmaceutical Dosage Form of an Antidepressant
TWI347942B (en) * 2005-06-22 2011-09-01 Lundbeck & Co As H Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base
RU2408368C2 (ru) 2005-06-27 2011-01-10 Биовэйл Лэборэториз Интернэшнл С.Р.Л. Препараты соли бупропиона с модифицированным высвобождением
US20070276419A1 (en) 2006-05-26 2007-11-29 Fox Hollow Technologies, Inc. Methods and devices for rotating an active element and an energy emitter on a catheter
US8784440B2 (en) 2008-02-25 2014-07-22 Covidien Lp Methods and devices for cutting tissue
CN102223847B (zh) 2008-10-13 2013-10-30 泰科保健集团有限合伙公司 用于操纵导管轴的装置和方法
KR101323553B1 (ko) 2009-04-29 2013-10-29 코비디엔 엘피 조직을 절제하고 연마하기 위한 방법 및 장치
KR101581091B1 (ko) 2009-05-14 2015-12-30 코비디엔 엘피 세척이 용이한 죽상반 절제 카테터 및 사용 방법
EP2913013B1 (de) 2009-12-02 2016-11-09 Covidien LP Verfahren und Vorrichtung zum Schneiden von Gewebe
IN2012DN04977A (de) 2009-12-11 2015-09-25 Tyco Healthcare
WO2011159697A1 (en) 2010-06-14 2011-12-22 Tyco Healthcare Group Lp Material removal device
WO2012058438A1 (en) 2010-10-28 2012-05-03 Tyco Healthcare Group Lp Material removal device and method of use
RU2553930C2 (ru) 2010-11-11 2015-06-20 Ковидиен Лп Гибкие фрагментирующие катетеры с визуализацией и способы их использования и изготовления
JP5806407B2 (ja) 2011-09-01 2015-11-10 コヴィディエン リミテッド パートナーシップ 螺旋駆動軸を有するカテーテルおよび製造方法
US9579157B2 (en) 2012-09-13 2017-02-28 Covidien Lp Cleaning device for medical instrument and method of use
US9943329B2 (en) 2012-11-08 2018-04-17 Covidien Lp Tissue-removing catheter with rotatable cutter
WO2015200702A1 (en) 2014-06-27 2015-12-30 Covidien Lp Cleaning device for catheter and catheter including the same
US10314667B2 (en) 2015-03-25 2019-06-11 Covidien Lp Cleaning device for cleaning medical instrument
US10292721B2 (en) 2015-07-20 2019-05-21 Covidien Lp Tissue-removing catheter including movable distal tip
US10314664B2 (en) 2015-10-07 2019-06-11 Covidien Lp Tissue-removing catheter and tissue-removing element with depth stop
US20240024288A1 (en) 2019-07-19 2024-01-25 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
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TR200000066T2 (tr) * 1997-07-08 2000-11-21 H. Lundbeck A/S Sitalopram hazırlanması için yöntem.
UA62985C2 (en) * 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
ES2149734T3 (es) * 1997-11-11 2003-02-16 Lundbeck & Co As H Metodo para la preparacion de citalopram.
PL199423B1 (pl) * 1998-10-20 2008-09-30 Lundbeck & Co As H Sposób wytwarzania citalopramu
NZ514671A (en) 1999-04-14 2003-10-31 H Method for the preparation of citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
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US6977306B2 (en) * 2000-05-02 2005-12-20 Sumitomo Chemical Company, Limited Citalopram hydrobromide crystal and method for crystallization thereof

Also Published As

Publication number Publication date
CH691537A5 (de) 2001-08-15
DE10108042A1 (de) 2001-10-18
NO20020356D0 (no) 2002-01-23
CN1680350A (zh) 2005-10-12
DK1227088T3 (da) 2003-12-22
FI109022B (fi) 2002-05-15
US20010031784A1 (en) 2001-10-18
SI1169314T2 (sl) 2011-08-31
NO315851B1 (no) 2003-11-03
WO2001068627A1 (en) 2001-09-20
ITMI20010406A1 (it) 2002-08-28
HUP0100531A2 (hu) 2002-01-28
DE60100786T2 (de) 2004-07-15
IL147339A (en) 2004-09-27
EP1169314B2 (de) 2011-06-01
YU68802A (sh) 2005-11-28
EA200200972A1 (ru) 2003-02-27
HU0100450D0 (en) 2001-04-28
DE60100022D1 (de) 2002-10-10
SI1169314T1 (en) 2002-12-31
FI20010225L (fi) 2001-09-14
EP1227088A1 (de) 2002-07-31
SE526022C2 (sv) 2005-06-14
EP1169314A1 (de) 2002-01-09
DE60100786D1 (de) 2003-10-23
AT4364U1 (de) 2001-06-25
BE1013210A3 (fr) 2001-10-02
CZ2001808A3 (cs) 2002-01-16
EP1169314B1 (de) 2002-09-04
HU0001581D0 (en) 2000-06-28
CA2360287C (en) 2003-09-09
DE20007303U1 (de) 2000-07-27
GB2357762B (en) 2002-01-30
IS5841A (is) 2001-09-14
PT1227088E (pt) 2003-12-31
DK173903B1 (da) 2002-02-11
FI20010156A0 (fi) 2001-01-25
AU3725201A (en) 2001-09-13
ES2173054T1 (es) 2002-10-16
US20060247451A1 (en) 2006-11-02
AU746664B2 (en) 2002-05-02
BG107065A (bg) 2003-05-30
CA2360287A1 (en) 2001-09-20
PT1169314E (pt) 2002-11-29
NO312031B1 (no) 2002-03-04
DE20121240U1 (de) 2002-07-04
CN1429220A (zh) 2003-07-09
KR20020080486A (ko) 2002-10-23
US20040167210A1 (en) 2004-08-26
SE0200730L (sv) 2002-08-29
MXPA02008793A (es) 2003-02-12
BR0109373A (pt) 2002-12-24
GB0102797D0 (en) 2001-03-21
JP2003527383A (ja) 2003-09-16
GB0105982D0 (en) 2001-05-02
IT1319645B1 (it) 2003-10-23
TR200202185T2 (tr) 2002-12-23
CZ292077B6 (cs) 2003-07-16
EP1227088B1 (de) 2003-09-17
ITMI20002425A1 (it) 2002-05-09
ES2159491A1 (es) 2001-10-01
SE517136C2 (sv) 2002-04-16
HU0100531D0 (en) 2001-03-28
FI20010225A0 (fi) 2001-02-07
HUP0100531A3 (en) 2004-04-28
HK1054750A1 (en) 2003-12-12
AR029811A1 (es) 2003-07-16
ES2173054T3 (es) 2002-12-16
IL147339A0 (en) 2002-08-14
NL1016435C1 (nl) 2000-11-06
ES2159491B1 (es) 2002-05-01
GR1003796B (el) 2002-02-08
FR2806086A1 (fr) 2001-09-14
CH691477A5 (de) 2001-07-31
US20030078442A1 (en) 2003-04-24
HRP20020756A2 (en) 2004-12-31
PL360158A1 (en) 2004-09-06
SI1227088T1 (en) 2003-12-31
AU2001100197B4 (en) 2001-12-06
CA2411732A1 (en) 2001-09-20
GB2357762A (en) 2001-07-04
NO20010619L (no) 2001-09-14
DE60100022T2 (de) 2003-03-06
NL1017413C1 (nl) 2001-09-13
NO20010619D0 (no) 2001-02-06
DK1169314T3 (da) 2002-10-14
AU2001100197A4 (en) 2001-09-20
ES2180471T3 (es) 2004-05-01
FR2806086B1 (fr) 2003-05-09
IL158072A0 (en) 2004-03-28
SK13132002A3 (sk) 2003-01-09
US20050165244A1 (en) 2005-07-28
US20040132808A1 (en) 2004-07-08
CN1258530C (zh) 2006-06-07
SK285528B6 (sk) 2007-03-01
ATE223396T1 (de) 2002-09-15
SE0200730D0 (sv) 2002-03-12
NO20020356L (no) 2001-09-14
SE0103046D0 (sv) 2001-09-14
DE10164687B4 (de) 2006-04-27
DE60100022T3 (de) 2011-11-17
ZA200207148B (en) 2003-04-23
SE0103046L (sv) 2001-11-14
ES2180471T1 (es) 2003-02-16
UA74360C2 (uk) 2005-12-15
US20050165092A1 (en) 2005-07-28
IES20010109A2 (en) 2002-02-20
DE1227088T1 (de) 2003-02-06

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