UA77950C2 - Use of mutants of cc chemokines for treatment of multiple sclerosis - Google Patents

Use of mutants of cc chemokines for treatment of multiple sclerosis Download PDF

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Publication number: UA77950C2
Authority: UA; Ukraine
Prior art keywords: mutant; chemokine; amino acids; mir; kamte5
Prior art date: 2000-10-04

Application number

UA2003044038A

Other languages

English (en)

Ukrainian (uk)

Original Assignee

Applied Research Systems

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-10-04

Filing date

2001-03-10

Publication date

2007-02-15

2001-03-10 Application filed by Applied Research Systems filed Critical Applied Research Systems

2007-02-15 Publication of UA77950C2 publication Critical patent/UA77950C2/uk

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/521—Chemokines
- C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Veterinary Medicine (AREA)
Neurosurgery (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Molecular Biology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Toxicology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Genetics & Genomics (AREA)
Psychiatry (AREA)
Hospice & Palliative Care (AREA)
Immunology (AREA)
Epidemiology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Enzymes And Modification Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

UA2003044038A 2000-10-04 2001-03-10 Use of mutants of cc chemokines for treatment of multiple sclerosis UA77950C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP00121665		2000-10-04
PCT/EP2001/011428 WO2002028419A2 (en)	2000-10-04	2001-10-03	Chemokine mutants in the treatment of multiple sclerosis

Publications (1)

Publication Number	Publication Date
UA77950C2 true UA77950C2 (en)	2007-02-15

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ID=8170011

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA2003044038A UA77950C2 (en)	2000-10-04	2001-03-10	Use of mutants of cc chemokines for treatment of multiple sclerosis

Country Status (30)

Country	Link
US (1)	US7402303B2 (de)
EP (1)	EP1326628B1 (de)
JP (1)	JP3908165B2 (de)
KR (1)	KR100837898B1 (de)
CN (1)	CN1285381C (de)
AR (1)	AR030854A1 (de)
AT (1)	ATE265222T1 (de)
AU (2)	AU1591902A (de)
BG (1)	BG66137B1 (de)
BR (1)	BR0114407A (de)
CA (1)	CA2423616C (de)
CZ (1)	CZ303409B6 (de)
DE (1)	DE60103078T2 (de)
DK (1)	DK1326628T3 (de)
EA (1)	EA006137B1 (de)
EE (1)	EE05174B1 (de)
ES (1)	ES2217199T3 (de)
HR (1)	HRP20030215B1 (de)
HU (1)	HUP0302194A3 (de)
IL (2)	IL155178A0 (de)
MX (1)	MXPA03003008A (de)
NO (1)	NO330278B1 (de)
PL (1)	PL204231B1 (de)
PT (1)	PT1326628E (de)
RS (1)	RS50738B (de)
SI (1)	SI1326628T1 (de)
SK (1)	SK287523B6 (de)
UA (1)	UA77950C2 (de)
WO (1)	WO2002028419A2 (de)
ZA (1)	ZA200302315B (de)

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* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2003051921A1 (en)	2001-12-17	2003-06-26	Applied Research Systems Ars Holding N.V.	Chemokine mutants acting as chemokine antagonists
US7335350B2 (en)	2002-04-04	2008-02-26	Laboratoires Serono Sa	Chemokines mutants having improved oral bioavailability
WO2004062688A2 (en) *	2002-12-23	2004-07-29	Applied Research Systems Ars Holding N.V.	Use of cc-chemokine mutants against liver diseases
AU2004283910A1 (en) *	2003-10-22	2005-05-06	Laboratoires Serono Sa	Novel CXCL8 antagonists
AT412785B (de) *	2003-12-04	2005-07-25	Kungl Andreas J Dr	Gag-bindungsproteine
ATE322506T1 (de) *	2004-01-19	2006-04-15	Ares Trading Sa	Verfahren zur reinigung von in bakterien exprimierten proteinen
GB0412400D0 (en) *	2004-06-03	2004-07-07	Univ Newcastle	Treatment of inflammatory conditions
EP2218748B1 (de) *	2005-09-03	2012-10-10	Samsung SDI Co., Ltd.	Polybenzoxazin Verbindung, Elektrolyt-Membran enthaltend dieser Verbindung und Elektrolyt-Membran benutzende Brenndstofzell
GB0614755D0 (en)	2006-07-25	2006-09-06	Univ Geneve	Cytokine derivatives
CA2695237A1 (en)	2007-08-02	2009-04-30	Novimmune S.A.	Anti-rantes antibodies and methods of use thereof
KR101784177B1 (ko) *	2010-02-08	2017-10-11	더 트러스티스 오브 더 유니버시티 오브 펜실바니아	Ｒａｎｔｅｓ를 암호화하는 핵산 분자, 그리고 이를 포함하는 조성물 및 이의 사용 방법
CA3101052A1 (en)	2018-05-28	2019-12-05	ORION Biotechnology Switzerland Sarl	Methods of inhibiting cerebral inflammation
US20250186520A1 (en) *	2020-10-26	2025-06-12	City Of Hope	Oncolytic virus compositions and methods for the treatment of cancer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5739103A (en) *	1993-11-12	1998-04-14	Dana-Farber Cancer Institute	Chemokine N-terminal deletion mutations
WO1998006751A1 (en) *	1996-08-16	1998-02-19	Research Corporation Technologies, Inc.	Mcp-3, rantes and mip-1alpha receptor antagonists
EP0906954A1 (de) *	1997-09-29	1999-04-07	Applied Research Systems ARS Holding N.V.	Aminoterminalen verkürzten C-C Chemokine als Chemokine Antagonist
DK1040191T3 (da) *	1997-12-23	2005-12-19	San Raffaele Centro Fond	RANTES-mutanter og terapeutiske anvendelser heraf
CA2361256A1 (en) *	1999-01-29	2000-08-03	James B. Rottman	Method of treating demyelinating inflammatory disease using ccr1 antagonists

2001
- 2001-03-10 UA UA2003044038A patent/UA77950C2/uk unknown
- 2001-10-03 DE DE60103078T patent/DE60103078T2/de not_active Expired - Lifetime
- 2001-10-03 BR BR0114407-3A patent/BR0114407A/pt not_active IP Right Cessation
- 2001-10-03 CZ CZ20030947A patent/CZ303409B6/cs not_active IP Right Cessation
- 2001-10-03 MX MXPA03003008A patent/MXPA03003008A/es active IP Right Grant
- 2001-10-03 AU AU1591902A patent/AU1591902A/xx active Pending
- 2001-10-03 RS YUP-257/03A patent/RS50738B/sr unknown
- 2001-10-03 EE EEP200300139A patent/EE05174B1/xx not_active IP Right Cessation
- 2001-10-03 CN CNB018199178A patent/CN1285381C/zh not_active Expired - Fee Related
- 2001-10-03 ZA ZA200302315A patent/ZA200302315B/en unknown
- 2001-10-03 IL IL15517801A patent/IL155178A0/xx unknown
- 2001-10-03 PT PT01986265T patent/PT1326628E/pt unknown
- 2001-10-03 HU HU0302194A patent/HUP0302194A3/hu unknown
- 2001-10-03 US US10/398,457 patent/US7402303B2/en not_active Expired - Fee Related
- 2001-10-03 DK DK01986265T patent/DK1326628T3/da active
- 2001-10-03 KR KR1020037004599A patent/KR100837898B1/ko not_active Expired - Fee Related
- 2001-10-03 AU AU2002215919A patent/AU2002215919B2/en not_active Ceased
- 2001-10-03 CA CA2423616A patent/CA2423616C/en not_active Expired - Fee Related
- 2001-10-03 WO PCT/EP2001/011428 patent/WO2002028419A2/en not_active Ceased
- 2001-10-03 PL PL362350A patent/PL204231B1/pl not_active IP Right Cessation
- 2001-10-03 HR HR20030215A patent/HRP20030215B1/xx not_active IP Right Cessation
- 2001-10-03 SI SI200130130T patent/SI1326628T1/xx unknown
- 2001-10-03 ES ES01986265T patent/ES2217199T3/es not_active Expired - Lifetime
- 2001-10-03 AT AT01986265T patent/ATE265222T1/de active
- 2001-10-03 EP EP01986265A patent/EP1326628B1/de not_active Expired - Lifetime
- 2001-10-03 EA EA200300439A patent/EA006137B1/ru not_active IP Right Cessation
- 2001-10-03 JP JP2002532243A patent/JP3908165B2/ja not_active Expired - Fee Related
- 2001-10-03 SK SK406-2003A patent/SK287523B6/sk not_active IP Right Cessation
- 2001-10-04 AR ARP010104684A patent/AR030854A1/es unknown
2003
- 2003-03-28 BG BG107685A patent/BG66137B1/bg unknown
- 2003-04-01 IL IL155178A patent/IL155178A/en not_active IP Right Cessation
- 2003-04-03 NO NO20031525A patent/NO330278B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
CA2423616C (en)	2010-03-16
EA006137B1 (ru)	2005-10-27
HUP0302194A3 (en)	2005-12-28
KR100837898B1 (ko)	2008-06-13
KR20030034238A (ko)	2003-05-01
NO330278B1 (no)	2011-03-21
CA2423616A1 (en)	2002-04-11
DK1326628T3 (da)	2004-08-09
SK287523B6 (sk)	2011-01-04
ATE265222T1 (de)	2004-05-15
CN1285381C (zh)	2006-11-22
JP2004510426A (ja)	2004-04-08
WO2002028419A2 (en)	2002-04-11
PT1326628E (pt)	2004-09-30
EP1326628B1 (de)	2004-04-28
EE200300139A (et)	2003-06-16
CZ2003947A3 (cs)	2003-11-12
DE60103078D1 (de)	2004-06-03
HUP0302194A2 (hu)	2003-10-28
ES2217199T3 (es)	2004-11-01
EE05174B1 (et)	2009-06-15
HRP20030215A2 (en)	2005-02-28
BG107685A (bg)	2003-11-28
EP1326628A2 (de)	2003-07-16
JP3908165B2 (ja)	2007-04-25
NO20031525L (no)	2003-04-03
HK1062811A1 (en)	2004-11-26
PL204231B1 (pl)	2009-12-31
AU1591902A (en)	2002-04-15
CN1477969A (zh)	2004-02-25
BG66137B1 (bg)	2011-07-29
YU25703A (sh)	2006-05-25
RS50738B (sr)	2010-08-31
WO2002028419A3 (en)	2002-06-13
SI1326628T1 (en)	2004-10-31
ZA200302315B (en)	2004-03-25
HRP20030215B1 (en)	2011-09-30
IL155178A0 (en)	2003-11-23
CZ303409B6 (cs)	2012-09-05
BR0114407A (pt)	2003-07-29
AR030854A1 (es)	2003-09-03
US7402303B2 (en)	2008-07-22
EA200300439A1 (ru)	2003-08-28
PL362350A1 (en)	2004-10-18
NO20031525D0 (no)	2003-04-03
SK4062003A3 (en)	2003-08-05
AU2002215919B2 (en)	2005-11-24
IL155178A (en)	2009-07-20
US20040101509A1 (en)	2004-05-27
DE60103078T2 (de)	2005-04-07
MXPA03003008A (es)	2003-07-14

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