NO954525D0 - BMP-10 sammensetninger - Google Patents

BMP-10 sammensetninger

Info

Publication number
NO954525D0
NO954525D0 NO954525A NO954525A NO954525D0 NO 954525 D0 NO954525 D0 NO 954525D0 NO 954525 A NO954525 A NO 954525A NO 954525 A NO954525 A NO 954525A NO 954525 D0 NO954525 D0 NO 954525D0
Authority
NO
Norway
Prior art keywords
bmp
proteins
compositions
disclosed
bone
Prior art date
Application number
NO954525A
Other languages
English (en)
Norwegian (no)
Other versions
NO954525L (no
Inventor
Anthony J Celeste
John M Wozney
Original Assignee
Genetics Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst filed Critical Genetics Inst
Publication of NO954525L publication Critical patent/NO954525L/no
Publication of NO954525D0 publication Critical patent/NO954525D0/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Epoxy Resins (AREA)
  • Dental Preparations (AREA)
  • Lubricants (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO954525A 1993-05-12 1995-11-09 BMP-10 sammensetninger NO954525D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6169593A 1993-05-12 1993-05-12
PCT/US1994/005290 WO1994026893A1 (en) 1993-05-12 1994-05-12 Bmp-10 compositions

Publications (2)

Publication Number Publication Date
NO954525L NO954525L (no) 1995-11-09
NO954525D0 true NO954525D0 (no) 1995-11-09

Family

ID=22037505

Family Applications (1)

Application Number Title Priority Date Filing Date
NO954525A NO954525D0 (no) 1993-05-12 1995-11-09 BMP-10 sammensetninger

Country Status (12)

Country Link
EP (1) EP0698095B1 (de)
JP (1) JPH09501305A (de)
KR (1) KR100231640B1 (de)
AT (1) ATE265529T1 (de)
AU (1) AU677849B2 (de)
BR (1) BR9406716A (de)
CA (1) CA2161807A1 (de)
DE (1) DE69433742T2 (de)
FI (1) FI955420A7 (de)
NO (1) NO954525D0 (de)
OA (1) OA10192A (de)
WO (1) WO1994026893A1 (de)

Families Citing this family (105)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE20004692U1 (de) 2000-03-14 2001-07-26 Sofamor Danek GmbH, 94469 Deggendorf Wirbelimplantat zum Einschrauben in einen Wirbelzwischenraum
US6150328A (en) 1986-07-01 2000-11-21 Genetics Institute, Inc. BMP products
BR9406715A (pt) * 1993-05-12 1996-02-06 Genetics Inst Molécula de DNA isolada célula hospedeira vetor método para produzir uma proteina (BMP-11) polipeptideo de proteina-11 morfogenética de osso purificada (BMP-11) e molécula de DNA quimérica
US6291206B1 (en) 1993-09-17 2001-09-18 Genetics Institute, Inc. BMP receptor proteins
DE69434651T2 (de) 1993-12-07 2007-03-08 Genetics Institute, Inc., Cambridge Bmp-12, bmp-13 und diese enthaltende sehne-induzierende zusammensetzungen
US5906827A (en) * 1994-06-03 1999-05-25 Creative Biomolecules, Inc. Matrix for the manufacture of autogenous replacement body parts
US5846770A (en) * 1994-11-22 1998-12-08 Genetics Institute, Inc. DNA molecules encoding human chordin
US5782919A (en) 1995-03-27 1998-07-21 Sdgi Holdings, Inc. Interbody fusion device and method for restoration of normal spinal anatomy
US5645084A (en) * 1995-06-07 1997-07-08 Danek Medical, Inc. Method for spinal fusion without decortication
US6206922B1 (en) 1995-03-27 2001-03-27 Sdgi Holdings, Inc. Methods and instruments for interbody fusion
US5635372A (en) * 1995-05-18 1997-06-03 Genetics Institute, Inc. BMP-15 compositions
WO1996039169A1 (en) 1995-06-05 1996-12-12 Genetics Institute, Inc. Methods and compositions for healing and repair of connective tissue attachment
US5902785A (en) * 1995-06-06 1999-05-11 Genetics Institute, Inc. Cartilage induction by bone morphogenetic proteins
US5989289A (en) 1995-10-16 1999-11-23 Sdgi Holdings, Inc. Bone grafts
US6423095B1 (en) 1995-10-16 2002-07-23 Sdgi Holdings, Inc. Intervertebral spacers
US5700774A (en) * 1996-03-26 1997-12-23 Genetics Institute, Inc. Compositions comprising bone morphogenic proteins and truncated parathyroid hormone related peptide, and methods of inducing cartilage by administration of same
US5965403A (en) * 1996-09-18 1999-10-12 Genetics Institute, Inc. Nucleic acids encoding bone morphogenic protein-16 (BMP-16)
KR20000052740A (ko) 1996-10-23 2000-08-25 에스디지아이 홀딩스 인코포레이티드 척수간극기
US6037519A (en) * 1997-10-20 2000-03-14 Sdgi Holdings, Inc. Ceramic fusion implants and compositions
EP0957943B2 (de) 1997-02-07 2008-11-26 Stryker Corporation Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung
US20010016646A1 (en) 1998-03-20 2001-08-23 David C. Rueger Osteogenic devices and methods of use thereof for repair of endochondral bone, osteochondral and chondral defects
US7041641B2 (en) 1997-03-20 2006-05-09 Stryker Corporation Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects
TW562807B (en) * 1997-04-01 2003-11-21 Chugai Pharmaceutical Co Ltd Novel secretory membrane protein
CA2291514C (en) 1997-05-30 2011-07-12 Mariel Therapeutics, Inc. Methods for evaluating tissue morphogenesis and activity
US5972368A (en) 1997-06-11 1999-10-26 Sdgi Holdings, Inc. Bone graft composites and spacers
US20020052026A1 (en) 1997-10-08 2002-05-02 Steven M. Vicik Methods of refolding proteins
US6511509B1 (en) 1997-10-20 2003-01-28 Lifenet Textured bone allograft, method of making and using same
WO1999029719A2 (en) * 1997-12-09 1999-06-17 Ontogeny, Inc. Pancreatic-derived factors, and uses related thereto
US6027917A (en) 1997-12-10 2000-02-22 Genetics Institute, Inc. Bone morphogenetic protein (BMP)-17 and BMP-18 compositions
US7147839B2 (en) 1998-05-29 2006-12-12 Curis, Inc. Methods for evaluating tissue morphogenesis and activity
WO2000007528A1 (en) 1998-08-06 2000-02-17 Sdgi Holdings, Inc. Composited intervertebral bone spacers
US6727224B1 (en) 1999-02-01 2004-04-27 Genetics Institute, Llc. Methods and compositions for healing and repair of articular cartilage
PT1223990E (pt) 1999-10-15 2004-12-31 Fidia Advanced Biopolymers Srl Formulacoes de acido hialuronico para administracao de proteinas osteogenicas
US8758438B2 (en) 2000-12-08 2014-06-24 Warsaw Orthopedic, Inc. Implant for orthopedic applications
US6752831B2 (en) 2000-12-08 2004-06-22 Osteotech, Inc. Biocompatible osteogenic band for repair of spinal disorders
EP1399023B1 (de) 2001-06-01 2008-04-30 Wyeth Zusammensetzungen für die systemische verabreichung von sequenzen, die für knochenmorphogenese-proteinen kodieren
TWI267378B (en) 2001-06-08 2006-12-01 Wyeth Corp Calcium phosphate delivery vehicles for osteoinductive proteins
CN100422334C (zh) * 2001-11-27 2008-10-01 内克西特股份有限公司 秀丽新杆线虫中真核生物蛋白质和核酸分子的生产
CH695985A5 (de) 2002-01-21 2006-11-15 Straumann Holding Ag Oberflächenmodifizierte Implantate.
WO2003093314A2 (en) 2002-05-03 2003-11-13 Millenium Biologix Inc. Connective tissue stimulating peptides
AU2004272072B2 (en) 2003-09-12 2010-07-08 Etex Corporation Injectable calcium phosphate solid rods and pastes for delivery of osteogenic proteins
US8372419B2 (en) 2004-03-10 2013-02-12 Scil Technology Gmbh Coated implants, their manufacturing and use thereof
EP1732589A2 (de) 2004-03-26 2006-12-20 Acceleron Pharma Inc. Bmp-3-propeptide und relevante verfahren
WO2005116052A2 (en) 2004-04-27 2005-12-08 Research Development Foundation ANTAGONISM OF TGF-β SUPERFAMILY RECEPTOR SIGNALING
US7741284B2 (en) 2004-05-12 2010-06-22 Acceleron Pharma Inc. BMP10 propeptides and related methods
ES2369629T3 (es) 2004-05-25 2011-12-02 Stryker Corporation Uso de op-1 para tratar defectos del cartílago.
US7749268B2 (en) 2004-05-26 2010-07-06 Warsaw Orthopedic, Inc. Methods for treating the spine
US7465706B2 (en) 2004-06-24 2008-12-16 Acceleron Pharma Inc. GDF3 propeptides and related methods
EP1771470B1 (de) 2004-07-23 2013-06-26 Acceleron Pharma Inc. Actrii-rezeptorpolypeptide, verfahren und zusammensetzungen
US7473678B2 (en) 2004-10-14 2009-01-06 Biomimetic Therapeutics, Inc. Platelet-derived growth factor compositions and methods of use thereof
KR20190006086A (ko) 2005-11-23 2019-01-16 악셀레론 파마 인코포레이티드 액티빈-ａｃｔｒⅱａ 길항제 및 골 성장을 촉진하기 위한 이들의 용도
US8128933B2 (en) 2005-11-23 2012-03-06 Acceleron Pharma, Inc. Method of promoting bone growth by an anti-activin B antibody
US8147860B2 (en) 2005-12-06 2012-04-03 Etex Corporation Porous calcium phosphate bone material
ES2427993T3 (es) 2006-02-09 2013-11-05 Biomimetic Therapeutics, Llc Composiciones y métodos para el tratamiento de hueso
EP2035030A2 (de) 2006-05-17 2009-03-18 Stryker Corporation Verwendung löslicher morphogener proteinkomplexe zur behandlung von knorpeldefekten
CA2656278C (en) 2006-06-30 2016-02-09 Biomimetic Therapeutics, Inc. Compositions and methods for treating rotator cuff injuries
US9161967B2 (en) 2006-06-30 2015-10-20 Biomimetic Therapeutics, Llc Compositions and methods for treating the vertebral column
AU2007234612B2 (en) 2006-12-14 2013-06-27 Johnson & Johnson Regenerative Therapeutics, Llc Protein stabilization formulations
US8895016B2 (en) 2006-12-18 2014-11-25 Acceleron Pharma, Inc. Antagonists of activin-actriia and uses for increasing red blood cell levels
CA2671925A1 (en) 2006-12-21 2008-07-10 Stryker Corporation Sustained-release formulations comprising crystals, macromolecular gels, and particulate suspensions of biologic agents
EP2111229B1 (de) 2007-02-01 2013-04-10 Acceleron Pharma, Inc. Zusammensetzungen enthaltend Activin-ActRIIA-Antagonisten zur Verwendung bei der Vorbeugung oder Behandlung der Brustkrebs-Metastasen oder des Brustkrebs Knochenverlustes
TWI782836B (zh) 2007-02-02 2022-11-01 美商艾瑟勒朗法瑪公司 衍生自ActRIIB的變體與其用途
ES2756725T3 (es) 2007-02-09 2020-04-27 Acceleron Pharma Inc Composiciones farmacéuticas que comprenden antagonistas de Activina-ActRIIA
US7678764B2 (en) 2007-06-29 2010-03-16 Johnson & Johnson Regenerative Therapeutics, Llc Protein formulations for use at elevated temperatures
CN101801405A (zh) 2007-08-07 2010-08-11 先进科技及再生医学有限责任公司 包含于酸性水溶液中的gdf-5的蛋白质配方
EP3243524A1 (de) 2007-09-18 2017-11-15 Acceleron Pharma Inc. Activin-actriia antagonisten und verfahren zur verringerung oder inhibierung der fsh-sekretion
EP2268302B1 (de) 2008-02-13 2014-04-09 Keith Hruska Bmp-7 zur behandlung von neointimaler hyperplasie
BRPI0911048A2 (pt) 2008-04-14 2015-12-29 Atrm Llc formulações líquidas tamponadas de gdf-5
SMT202300222T1 (it) 2008-08-14 2023-09-06 Acceleron Pharma Inc Trappole di gdf
US8216997B2 (en) 2008-08-14 2012-07-10 Acceleron Pharma, Inc. Methods for increasing red blood cell levels and treating anemia using a combination of GDF traps and erythropoietin receptor activators
KR20110067035A (ko) 2008-09-09 2011-06-20 바이오미메틱 세라퓨틱스, 인크. 건 및 인대 손상의 치료를 위한 혈소판-유래 성장 인자 조성물 및 방법
US8138142B2 (en) 2009-01-13 2012-03-20 Acceleron Pharma Inc. Methods for increasing adiponectin in a patient in need thereof
SG173634A1 (en) 2009-02-12 2011-09-29 Stryker Corp COMPOSITIONS AND METHODS FOR MINIMALLY-INVASIVE SYSTEMIC DELIVERY OF PROTEINS INCLUDING TGF-ß SUPERFAMILY MEMBERS
WO2010093925A2 (en) 2009-02-12 2010-08-19 Stryker Corporation PERIPHERAL ADMINISTRATION OF PROTEINS INCLUDING TGF-β SUPERFAMILY MEMBERS FOR TREATMENT OF SYSTEMIC DISORDERS AND DISEASE
US20120148539A1 (en) 2009-03-24 2012-06-14 Moulay Hicham Alaoui-Ismaili Methods and Compositions for Tissue Engineering
BRPI1010587A2 (pt) 2009-06-08 2019-04-09 Acceleron Pharma Inc. métodos para aumentar adipócitos termogênicos
WO2010144696A1 (en) 2009-06-11 2010-12-16 Burnham Institute For Medical Research Directed differentiation of stem cells
EP2440577A4 (de) 2009-06-12 2013-01-23 Acceleron Pharma Inc Verkürzte actriib-fc-fusionsproteine
US9399086B2 (en) 2009-07-24 2016-07-26 Warsaw Orthopedic, Inc Implantable medical devices
WO2011031856A1 (en) 2009-09-09 2011-03-17 Stryker Corporation Bmp -7 for use in treating pain induced by injuries and diseases of an articular joint
EP2352750B1 (de) 2009-09-17 2012-06-13 Stryker Corporation Puffer zur steuerung des ph-wertes knochenmorphogenetischer proteine
JP6267425B2 (ja) 2009-11-17 2018-01-24 アクセルロン ファーマ， インコーポレイテッド 筋ジストロフィー治療のためのユートロフィン誘導に関するａｃｔｒｉｉｂタンパク質およびその改変体およびその使用
WO2011087768A1 (en) 2009-12-22 2011-07-21 Stryker Corporation Bmp-7 variants with reduced immunogenicity
CN102811622A (zh) 2010-02-22 2012-12-05 生物模拟治疗公司 用于治疗腱病的血小板衍生生长因子组合物和方法
WO2011139594A2 (en) 2010-04-27 2011-11-10 Medtronic, Inc. Artificial bursa for intra-articular drug delivery
CN103298832A (zh) 2010-11-08 2013-09-11 阿塞勒隆制药公司 Actriia结合剂及其用途
US9809636B2 (en) 2012-04-06 2017-11-07 Acceleron Pharma Inc. Methods for increasing red blood cell levels comprising administering BMP9
US10034945B2 (en) 2012-07-13 2018-07-31 Trustees Of Tufts College Silk powder compaction for production of constructs with high mechanical strength and stiffness
NZ707477A (en) 2012-11-02 2019-09-27 Celgene Corp Activin-actrii antagonists and uses for treating bone and other disorders
US9572912B2 (en) 2013-04-19 2017-02-21 Theracell, Inc. Demineralized bone fibers having controlled geometry and shapes and methods thereof
WO2015192111A1 (en) 2014-06-13 2015-12-17 Acceleron Pharma, Inc. Methods and compositions for treating ulcers
GB201412290D0 (en) 2014-07-10 2014-08-27 Cambridge Entpr Ltd Novel use
MA41052A (fr) 2014-10-09 2017-08-15 Celgene Corp Traitement d'une maladie cardiovasculaire à l'aide de pièges de ligands d'actrii
JP2018501307A (ja) 2014-12-03 2018-01-18 セルジーン コーポレイション アクチビン−ＡｃｔＲＩＩアンタゴニスト及び貧血を治療するための使用
US10610366B2 (en) 2015-01-29 2020-04-07 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
KR20180019646A (ko) 2015-06-17 2018-02-26 워쏘우 오르쏘페딕 인코포레이티드 옥시스테롤을 포함하는 임플란트 및 사용 방법
ES2846848T3 (es) 2015-10-26 2021-07-29 Harvard College Polisacáridos reducidos y oxidados y métodos de uso de los mismos
US10688222B2 (en) 2016-11-21 2020-06-23 Warsaw Orthopedic, Inc. Lyophilized moldable implants containing an oxysterol
US10639157B2 (en) 2017-03-14 2020-05-05 Theracell, Inc. Demineralized bone fiber composition for use in minimally invasive surgery
US11464888B2 (en) 2017-06-12 2022-10-11 Warsaw Orthopedic, Inc. Moldable formulations containing an oxysterol in an acellular tissue matrix
AU2018313306B2 (en) 2017-08-11 2024-06-13 Arteriocyte Medical Systems, Inc. Demineralized bone fiber composition for augmentation of fixation
US11103618B2 (en) 2018-02-22 2021-08-31 Warsaw Orthopedic, Inc. Demineralized bone matrix having improved handling characteristics
WO2020163828A1 (en) 2019-02-09 2020-08-13 Theracell, Inc. Demineralized bone fiber implant compositions and methods for augmenting fixation in bone repair
US11498880B2 (en) 2019-07-26 2022-11-15 Warsaw Orthopedic, Inc. Calcium phosphate granules and methods of making them
CN113603792B (zh) * 2021-08-26 2023-06-30 深圳市人民医院 一种重组骨形态发生蛋白-2及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06500991A (ja) * 1990-05-16 1994-01-27 ジェネティックス・インスティテュート・インコーポレイテッド 骨および軟骨誘導蛋白質
AU652472B2 (en) * 1991-06-25 1994-08-25 Genetics Institute, Llc BMP-9 compositions

Also Published As

Publication number Publication date
JPH09501305A (ja) 1997-02-10
OA10192A (en) 1996-12-18
BR9406716A (pt) 1996-02-06
NO954525L (no) 1995-11-09
KR960701997A (ko) 1996-03-28
DE69433742D1 (de) 2004-06-03
FI955420L (fi) 1996-01-08
WO1994026893A1 (en) 1994-11-24
ATE265529T1 (de) 2004-05-15
FI955420A0 (fi) 1995-11-10
KR100231640B1 (ko) 1999-12-01
EP0698095B1 (de) 2004-04-28
DE69433742T2 (de) 2005-07-07
CA2161807A1 (en) 1994-11-24
AU6910794A (en) 1994-12-12
EP0698095A1 (de) 1996-02-28
FI955420A7 (fi) 1996-01-08
AU677849B2 (en) 1997-05-08

Similar Documents

Publication Publication Date Title
ATE265529T1 (de) Bmp-10 zusammensetzungen
ATE223486T1 (de) Bmp-9 zusammensetzungen
DK0536186T3 (da) Knogle- og brusk-dannelsesfremkaldende proteiner
DK0429570T3 (da) Osteoinducerende præparater
CA2108770A1 (en) Bmp-9 compositions
DE69433530D1 (de) Bmp-11 zusammensetzungen
DE69233022D1 (de) Rekombinante knochenmorphogenetische protein heterodimere, zusammensetzungen und verfahren zur verwendung
PT733109E (pt) Proteinas morfogeneticas dos 0ss0s pmo-12 e pmo-13 e as suas composicoes para inducao de tendao
ES2088006T3 (es) Composiciones farmaceuticas osteoinductivas.
ATE153696T1 (de) Verfahren und desoxyribonukleinsäure zur herstellung von gewebefaktor-protein
DE69133338D1 (de) Bmp-5-derivate
DE69821793D1 (de) Neuronale verwendungen des bmp-11
DE69726884D1 (de) Menschliches sdf-5 protein und diesbezügliche zusammensetzungen

Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application