ATE267183T1 - Piperazine und piperidine derivate - Google Patents

Piperazine und piperidine derivate

Info

Publication number: ATE267183T1
Authority: AT; Austria
Prior art keywords: piperazine; piperidine derivatives; piperidine; derivatives
Prior art date: 1998-11-13

Application number

AT99955980T

Other languages

English (en)

Inventor

Gerrit P Toorop

Roelof W Feenstra

Der Heijden Johannes A M Van

Johannes Mos

Stephen K Long

Gerben M Visser

Cornelis G Kruse

Scharrenburg Gustaaf J M Van

Anne G Hf Toorop

Original Assignee

Duphar Int Res

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-13

Filing date

1999-11-10

Publication date

2004-06-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8234340&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE267183(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1999-11-10 Application filed by Duphar Int Res filed Critical Duphar Int Res

2004-06-15 Application granted granted Critical

2004-06-15 Publication of ATE267183T1 publication Critical patent/ATE267183T1/de

Links

GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 title 2
NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical class C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/32—Oxygen atoms
- C07D209/34—Oxygen atoms in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
- C07D277/62—Benzothiazoles
- C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Hospice & Palliative Care (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Hydrogenated Pyridines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

AT99955980T 1998-11-13 1999-11-10 Piperazine und piperidine derivate ATE267183T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP98203871		1998-11-13
PCT/EP1999/008702 WO2000029397A1 (en)	1998-11-13	1999-11-10	New piperazine and piperidine compounds

Publications (1)

Publication Number	Publication Date
ATE267183T1 true ATE267183T1 (de)	2004-06-15

Family

ID=8234340

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT99955980T ATE267183T1 (de)	1998-11-13	1999-11-10	Piperazine und piperidine derivate

Country Status (27)

Country	Link
US (1)	US6780864B1 (de)
EP (1)	EP1131308B1 (de)
JP (1)	JP3638874B2 (de)
KR (1)	KR100619465B1 (de)
CN (1)	CN1225462C (de)
AR (1)	AR021256A1 (de)
AT (1)	ATE267183T1 (de)
AU (1)	AU756470B2 (de)
BR (1)	BR9915293B1 (de)
CA (1)	CA2350137C (de)
CZ (1)	CZ299774B6 (de)
DE (1)	DE69917478T2 (de)
DK (1)	DK1131308T3 (de)
DZ (1)	DZ2934A1 (de)
ES (1)	ES2217833T3 (de)
HU (1)	HUP0104922A3 (de)
IL (2)	IL143028A0 (de)
MX (1)	MXPA01004854A (de)
NO (1)	NO318888B1 (de)
NZ (1)	NZ511584A (de)
PL (1)	PL193685B1 (de)
RU (1)	RU2225406C2 (de)
SI (1)	SI1131308T1 (de)
SK (1)	SK285648B6 (de)
TW (1)	TWI252230B (de)
UA (1)	UA71590C2 (de)
WO (1)	WO2000029397A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
UA73981C2 (en)	2000-03-10	2005-10-17	Merck Patent Gmbh	(r)-(-)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane for treatment of extrapyramidal movement disorders (variants), pharmaceutical composition and kit
JP2003532676A (ja) *	2000-05-12	2003-11-05	ソルベイ・フアーマシユーチカルズ・ベー・ブイ	ＣＮＳ障害を治療するための組合せられたドーパミンＤ２、５−ＨＴ１Ａおよびαアドレノレセプターアゴニスト作用、を有する化合物の使用
ATE255578T1 (de) *	2000-05-12	2003-12-15	Solvay Pharm Bv	Piperazin- und piperidinverbindungen
BR0115297A (pt) *	2000-11-14	2003-08-26	Merck Patent Ges Mit Beschonkt	Usos de antagonistas seletivos do receptor de dopamina d2 e agonistas do receptor 5-ht1a combinados
AR034206A1 (es)	2001-02-16	2004-02-04	Solvay Pharm Bv	Un procedimiento para la preparacion de mesilatos de derivados de piperazina y dichos mesilatos
US6800648B2 (en) *	2001-04-26	2004-10-05	Wyeth	Antipsychotic aminomethyl derivatives of 7,8-dihydro-3H-1,6,9-trioxa-3-AZA-cyclopenta[a]naphthalen-2-one
US6743796B2 (en)	2001-05-07	2004-06-01	Wyeth	Piperazinyl-isatins
DK1408976T5 (da)	2001-07-20	2011-01-10	Psychogenics Inc	Behandling af ADHD (Attention deficit hyperactivity disorder)
EP1408964B1 (de)	2001-07-26	2007-01-24	MERCK PATENT GmbH	Verwendung von 2- 5-(4-fluorphenyl)-3-pyridylmethylaminomethyl-chroman und seiner physiologisch annehmbaren salze
EP1336406A1 (de) *	2002-02-14	2003-08-20	Solvay Pharmaceuticals B.V.	Partieller Dopamin-D2 Rezeptoragonist plus Substanzen mit Serotonin- und/oder Noradrenalin inhibitorischer Aktivität
AU2003244160A1 (en) *	2002-06-25	2004-01-06	Sumitomo Pharmaceuticals Co., Ltd.	Novel benzoxazolinone derivative
US7435738B2 (en)	2003-08-18	2008-10-14	Solvay Pharmaceuticals, Inc.	Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)
US7596407B2 (en)	2004-03-26	2009-09-29	Solvay Pharmaceuticals, B.V.	Transdermal iontophoretic delivery of piperazinyl-2(3H)-benzoxazolone compounds
EP1595542A1 (de) *	2004-03-26	2005-11-16	Solvay Pharmaceuticals B.V.	Transdermale iontophoretische Verabreichung von Piperazinyl-2(3H)-benzoxazolon-Verbindungen
DE602005016244D1 (de)	2004-05-27	2009-10-08	Ucb Pharma Sa	Benzoxazolonderivate, verfahren zu deren herstellung und deren anwendungen
US7405216B2 (en)	2004-08-18	2008-07-29	Solvay Pharmaceuticals, B.V.	Stable crystalline form of bifeprunox mesylate (7-[4-([1,1′-biphenyl]-3-ylmethyl)-1-piperazinyl]-2(3H)-benzoxazolone monomethanesulfonate)
US7964604B2 (en)	2005-02-18	2011-06-21	Solvay Pharmaceuticals B.V.	Bifeprunox mesylate maintenance dose compositions and methods for using the same
US7423040B2 (en)	2005-02-18	2008-09-09	Irene Eijgendaal	Stable crystalline form of bifeprunox mesylate, dosage forms thereof and methods for using same
US7750013B2 (en)	2005-08-22	2010-07-06	Solvay Pharmaceuticals, B.V.	N-oxides as prodrugs of piperazine and piperidine derivatives
AR058022A1 (es) *	2005-08-22	2008-01-23	Solvay Pharm Bv	Derivados de benzooxazoles, composiciones farmaceuticas y su uso para el tratamiento de desordenes del sistema nervioso.
WO2007023141A1 (en) *	2005-08-22	2007-03-01	Solvay Pharmaceuticals B.V.	N-oxides as prodrugs of piperazine & piperidine derivatives
US8106056B2 (en)	2006-06-16	2012-01-31	Solvay Pharmaceuticals B.V.	Combination preparations comprising bifeprunox and a dopamine agonist
US7786126B2 (en)	2006-06-16	2010-08-31	Solvay Pharmaceuticals B.V.	Combination preparations comprising SLV308 and a dopamine agonist
UY32934A (es) *	2009-10-12	2011-05-31	Abbott Healthcare Products Bv	Monohidrato de pardoprunox
US11103499B2 (en)	2016-08-26	2021-08-31	EXCIVA (UG) (haftungsbeschränkt)	Compositions and methods thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2567884B1 (fr) *	1984-07-19	1987-03-06	Roussel Uclaf	Nouveaux derives de l'indole, leur preparation, leur application comme medicaments et les compositions les renfermant
EP0185429A1 (de) *	1984-12-21	1986-06-25	Duphar International Research B.V	Bizyklische Piperazine
DE3586794T2 (de) *	1984-12-21	1993-05-27	Duphar Int Res	Arzneimittel mit psychotroper wirkung.
DK148392D0 (da)	1992-12-09	1992-12-09	Lundbeck & Co As H	Heterocykliske forbindelser
IL114026A (en)	1994-06-08	1999-06-20	Lundbeck & Co As H	4-aryl-1-(indanmethyl dihydrobenzofuranmethyl or dihydrobenzo thiophenemethyl) piperidines tetrahydropyridines or piperazines and pharmaceutical compositions containing them
WO1996003400A1 (en) *	1994-07-26	1996-02-08	Pfizer Inc.	4-indole derivatives as serotonin agonists and antagonists
ES2271967T3 (es)	1996-03-29	2007-04-16	Duphar International Research B.V	Compuestos de piperazina y piperidina.
EP0900792B1 (de)	1997-09-02	2003-10-29	Duphar International Research B.V	Piperidin- und Piperazin Derivate als 5-HT1-Rezeptor-Agonisten

1999
- 1999-10-11 UA UA2001064076A patent/UA71590C2/uk unknown
- 1999-11-10 EP EP99955980A patent/EP1131308B1/de not_active Expired - Lifetime
- 1999-11-10 KR KR1020017005978A patent/KR100619465B1/ko not_active Expired - Fee Related
- 1999-11-10 MX MXPA01004854A patent/MXPA01004854A/es not_active IP Right Cessation
- 1999-11-10 SK SK649-2001A patent/SK285648B6/sk not_active IP Right Cessation
- 1999-11-10 ES ES99955980T patent/ES2217833T3/es not_active Expired - Lifetime
- 1999-11-10 SI SI9930574T patent/SI1131308T1/xx unknown
- 1999-11-10 RU RU2001116117/04A patent/RU2225406C2/ru not_active IP Right Cessation
- 1999-11-10 DK DK99955980T patent/DK1131308T3/da active
- 1999-11-10 HU HU0104922A patent/HUP0104922A3/hu unknown
- 1999-11-10 CZ CZ20011657A patent/CZ299774B6/cs not_active IP Right Cessation
- 1999-11-10 CN CNB998130710A patent/CN1225462C/zh not_active Expired - Fee Related
- 1999-11-10 US US09/831,149 patent/US6780864B1/en not_active Expired - Fee Related
- 1999-11-10 BR BRPI9915293-2A patent/BR9915293B1/pt not_active IP Right Cessation
- 1999-11-10 AU AU12709/00A patent/AU756470B2/en not_active Ceased
- 1999-11-10 IL IL14302899A patent/IL143028A0/xx active IP Right Grant
- 1999-11-10 PL PL99347635A patent/PL193685B1/pl not_active IP Right Cessation
- 1999-11-10 WO PCT/EP1999/008702 patent/WO2000029397A1/en not_active Ceased
- 1999-11-10 DZ DZ990234A patent/DZ2934A1/xx active
- 1999-11-10 NZ NZ511584A patent/NZ511584A/xx not_active IP Right Cessation
- 1999-11-10 DE DE69917478T patent/DE69917478T2/de not_active Expired - Lifetime
- 1999-11-10 AT AT99955980T patent/ATE267183T1/de active
- 1999-11-10 CA CA002350137A patent/CA2350137C/en not_active Expired - Fee Related
- 1999-11-10 JP JP2000582384A patent/JP3638874B2/ja not_active Expired - Fee Related
- 1999-11-12 AR ARP990105763A patent/AR021256A1/es active IP Right Grant
2000
- 2000-01-05 TW TW089100097A patent/TWI252230B/zh not_active IP Right Cessation
2001
- 2001-05-08 IL IL143028A patent/IL143028A/en not_active IP Right Cessation
- 2001-05-11 NO NO20012339A patent/NO318888B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
DZ2934A1 (fr)	2004-03-15
SI1131308T1 (en)	2004-10-31
BR9915293B1 (pt)	2011-11-01
JP3638874B2 (ja)	2005-04-13
HUP0104922A3 (en)	2003-05-28
PL193685B1 (pl)	2007-03-30
WO2000029397A1 (en)	2000-05-25
AU756470B2 (en)	2003-01-16
TWI252230B (en)	2006-04-01
KR100619465B1 (ko)	2006-09-05
CZ20011657A3 (cs)	2001-10-17
IL143028A0 (en)	2002-04-21
CA2350137C (en)	2008-04-22
US6780864B1 (en)	2004-08-24
MXPA01004854A (es)	2005-07-25
CN1378540A (zh)	2002-11-06
NO20012339L (no)	2001-05-11
AR021256A1 (es)	2002-07-03
IL143028A (en)	2006-12-10
CZ299774B6 (cs)	2008-11-19
EP1131308A1 (de)	2001-09-12
AU1270900A (en)	2000-06-05
PL347635A1 (en)	2002-04-22
NO20012339D0 (no)	2001-05-11
DE69917478D1 (de)	2004-06-24
HUP0104922A2 (en)	2002-08-28
DE69917478T2 (de)	2004-09-16
NZ511584A (en)	2003-01-31
SK285648B6 (sk)	2007-05-03
SK6492001A3 (en)	2001-10-08
JP2002530276A (ja)	2002-09-17
EP1131308B1 (de)	2004-05-19
BR9915293A (pt)	2001-08-07
HK1039489A1 (en)	2002-04-26
RU2225406C2 (ru)	2004-03-10
DK1131308T3 (da)	2004-06-28
NO318888B1 (no)	2005-05-18
CA2350137A1 (en)	2000-05-25
UA71590C2 (en)	2004-12-15
KR20010080995A (ko)	2001-08-25
CN1225462C (zh)	2005-11-02
ES2217833T3 (es)	2004-11-01

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2004-12-15

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Publication	Publication Date	Title
DE69917478D1 (de)	2004-06-24	Piperazine und piperidine derivate
NO20023787L (no)	2002-10-11	Piperazin- og piperidinderivater
ATE305933T1 (de)	2005-10-15	Piperazin derivate
ATE353326T1 (de)	2007-02-15	Piperazin-derivate
ATE407131T1 (de)	2008-09-15	Substituierte bipiperidine -zwischenverbindungen und deren derivate
BR9712037A (pt)	1999-08-24	Derivados de piperazina
DE69911378D1 (de)	2003-10-23	Fluorierte ionomere und verwendung davon
DE69913169D1 (de)	2004-01-08	Sportschuh und dafür vorgesehene dornen
AR028343A1 (es)	2003-05-07	Derivados de pirrolidina y piperidina
DE69903143D1 (de)	2002-10-31	Chromanon und thiochromanon derivate
ATE278695T1 (de)	2004-10-15	Piperidinderivate
DE60032898D1 (de)	2007-02-22	Arylthiazolidindion- und aryloxazolidinderivate
ATE321042T1 (de)	2006-04-15	Piperazin-derivate
DE69903961D1 (de)	2002-12-19	Muscarinagonisten und antagonisten
HU9802129D0 (en)	1998-11-30	New piperazine and piperidine derivatives
PT1283838E (pt)	2004-04-30	Compostos de piperazina e de piperidina
ATE266637T1 (de)	2004-05-15	3,3-biarylpiperidin- und 3,3- biarylmorpholinderivate
DE60029075D1 (de)	2006-08-10	Kopiergerät und Kopierverfahren
DE69916694D1 (de)	2004-06-03	2-Hydroxy-5-methyl-hexan-3-on und 3-hydroxy-5-methyl-hexan-2-on
ATE247105T1 (de)	2003-08-15	Antipsychotische 4-(1h-indolyl-1-yl)-1- substituierte piperidine derivate
DE69904738D1 (de)	2003-02-06	2-phenylpyran-4-one derivate
DK0937458T3 (da)	2005-05-17	Pyrrolidin- og piperidinderivater
NO992302L (no)	1999-05-14	Piperidin-derivater
DE60036885D1 (de)	2007-12-06	Succinimidverbindungen und deren verwendung
ATE362915T1 (de)	2007-06-15	Heterocyclische derivate und arzneistoffe