ATE269154T1 - Lipidnanokapseln, seine herstellungsverfahren sowie verwendung als medizin - Google Patents

Lipidnanokapseln, seine herstellungsverfahren sowie verwendung als medizin

Info

Publication number
ATE269154T1
ATE269154T1 AT01911828T AT01911828T ATE269154T1 AT E269154 T1 ATE269154 T1 AT E269154T1 AT 01911828 T AT01911828 T AT 01911828T AT 01911828 T AT01911828 T AT 01911828T AT E269154 T1 ATE269154 T1 AT E269154T1
Authority
AT
Austria
Prior art keywords
medicine
lipidnano
capsules
production process
producing
Prior art date
Application number
AT01911828T
Other languages
English (en)
Inventor
Beatrice Heurtault
Patrick Saulnier
Jean-Pierre Benoit
Jacques-Emile Proust
Brigitte Pech
Joel Richard
Original Assignee
Mainelab
Univ Angers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mainelab, Univ Angers filed Critical Mainelab
Application granted granted Critical
Publication of ATE269154T1 publication Critical patent/ATE269154T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5123—Organic compounds, e.g. fats, sugars
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5146—Organic macromolecular compounds; Dendrimers obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyamines, polyanhydrides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/0004—Preparation of sols
    • B01J13/0026—Preparation of sols containing a liquid organic phase
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
    • B01J13/02—Making microcapsules or microballoons
    • B01J13/06—Making microcapsules or microballoons by phase separation
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/017—Mixtures of compounds
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/14—Derivatives of phosphoric acid
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K23/00—Use of substances as emulsifying, wetting, dispersing, or foam-producing agents
    • C09K23/34—Higher-molecular-weight carboxylic acid esters
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Materials Engineering (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01911828T 2000-03-02 2001-03-02 Lipidnanokapseln, seine herstellungsverfahren sowie verwendung als medizin ATE269154T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0002688A FR2805761B1 (fr) 2000-03-02 2000-03-02 Nanocapsules lipidiques, procede de preparation et utilisation comme medicament
PCT/FR2001/000621 WO2001064328A1 (fr) 2000-03-02 2001-03-02 Nanocapsules lipidiques, procede de preparation et utilisation comme medicament

Publications (1)

Publication Number Publication Date
ATE269154T1 true ATE269154T1 (de) 2004-07-15

Family

ID=8847644

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01911828T ATE269154T1 (de) 2000-03-02 2001-03-02 Lipidnanokapseln, seine herstellungsverfahren sowie verwendung als medizin

Country Status (22)

Country Link
US (2) US8057823B2 (de)
EP (1) EP1265698B1 (de)
JP (1) JP4790187B2 (de)
KR (1) KR100638527B1 (de)
CN (1) CN1257011C (de)
AT (1) ATE269154T1 (de)
AU (2) AU4075301A (de)
BR (1) BRPI0108921B8 (de)
CA (1) CA2401766C (de)
DE (1) DE60103863T2 (de)
DK (1) DK1265698T3 (de)
ES (1) ES2221640T3 (de)
FR (1) FR2805761B1 (de)
HU (1) HU226483B1 (de)
IL (1) IL151560A0 (de)
MX (1) MXPA02008638A (de)
NO (1) NO334188B1 (de)
PT (1) PT1265698E (de)
SI (1) SI1265698T1 (de)
TR (1) TR200401812T4 (de)
WO (1) WO2001064328A1 (de)
ZA (1) ZA200206985B (de)

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AU2003247061B2 (en) * 2002-06-11 2008-10-09 Ethypharm Stealth lipid nanocapsules, methods for the preparation thereof and use thereof as a carrier for active principle(s)
CA2504329C (en) * 2002-11-01 2013-08-20 Biodelivery Sciences International, Inc. Geodate delivery vehicles
FR2849379B1 (fr) * 2002-12-26 2005-02-11 Cosnessens Encapsulation d'actifs liposolubles
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FR2864900B1 (fr) 2004-01-09 2007-10-12 Oreal Dispersion aqueuse de nanocapsules a coeur huileux
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FR2916973B1 (fr) * 2007-06-11 2010-02-26 Univ Angers Nanocapsules a coeur lipidique chargees en actif(s) hydrosoluble(s) ou hydrodispersible(s)
FR2916974B1 (fr) * 2007-06-11 2010-11-26 Univ Angers Procede de preparation de nanoparticules lipidiques
FR2917976B1 (fr) * 2007-06-29 2010-05-28 Galderma Sa Composition dermatologique comprenant des vehicules lipidiques de calcitriol, son procede de preparation et son utilisation
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FR2934955B1 (fr) * 2008-08-14 2011-07-08 Commissariat Energie Atomique Encapsulation d'agents therapeutiques lipophiles ou amphiphiles dans des nanoemulsions
FR2939699B1 (fr) * 2008-12-12 2011-05-06 Univ Angers Procede de preparation de nanoparticules lipidiques
FR2943544B1 (fr) * 2009-03-31 2012-04-20 Univ Angers Procede de preparation de capsules lipidiques fonctionnalisees.
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FR2988609B1 (fr) * 2012-03-30 2015-09-04 Commissariat Energie Atomique Formulation pour l'hormonotherapie
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FR3017294B1 (fr) 2014-02-07 2021-10-01 Atlangram Nanoparticules lipidiques comprenant un antibiotique et leurs utilisations en therapie
EP3148590A1 (de) * 2014-05-30 2017-04-05 AbbVie Deutschland GmbH & Co. KG Poly(alkyl-2-cyanoacrylat)nanokapseln mit hoher wirkstoffladung
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Also Published As

Publication number Publication date
EP1265698A1 (de) 2002-12-18
PT1265698E (pt) 2004-11-30
HUP0300209A3 (en) 2005-04-28
AU4075301A (en) 2001-09-12
FR2805761B1 (fr) 2002-08-30
MXPA02008638A (es) 2004-09-06
US20030152635A1 (en) 2003-08-14
WO2001064328A1 (fr) 2001-09-07
FR2805761A1 (fr) 2001-09-07
NO334188B1 (no) 2014-01-13
CA2401766A1 (fr) 2001-09-07
US8057823B2 (en) 2011-11-15
IL151560A0 (en) 2003-04-10
DE60103863D1 (de) 2004-07-22
HUP0300209A2 (hu) 2003-06-28
ZA200206985B (en) 2003-10-07
DE60103863T2 (de) 2005-06-30
CN1257011C (zh) 2006-05-24
NO20024181D0 (no) 2002-09-02
NO20024181L (no) 2002-10-22
CA2401766C (fr) 2009-05-19
KR20030003692A (ko) 2003-01-10
EP1265698B1 (de) 2004-06-16
US20090238865A1 (en) 2009-09-24
JP4790187B2 (ja) 2011-10-12
ES2221640T3 (es) 2005-01-01
SI1265698T1 (en) 2004-10-31
BR0108921A (pt) 2003-01-21
HU226483B1 (en) 2009-03-02
KR100638527B1 (ko) 2006-10-25
BRPI0108921B8 (pt) 2021-05-25
AU2001240753B2 (en) 2005-04-14
DK1265698T3 (da) 2004-10-25
CN1419472A (zh) 2003-05-21
BR0108921B1 (pt) 2014-09-30
JP2003525257A (ja) 2003-08-26
TR200401812T4 (tr) 2004-09-21

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