ATE277604T1 - Quervernetzte stärke mit hohem amyloseanteil und funktionellen gruppen als matrix für langsame freisetzung pharmazeutischer wirkstoffe - Google Patents

Quervernetzte stärke mit hohem amyloseanteil und funktionellen gruppen als matrix für langsame freisetzung pharmazeutischer wirkstoffe

Info

Publication number
ATE277604T1
ATE277604T1 AT99936029T AT99936029T ATE277604T1 AT E277604 T1 ATE277604 T1 AT E277604T1 AT 99936029 T AT99936029 T AT 99936029T AT 99936029 T AT99936029 T AT 99936029T AT E277604 T1 ATE277604 T1 AT E277604T1
Authority
AT
Austria
Prior art keywords
cross
high amylose
slow release
matrix
functional groups
Prior art date
Application number
AT99936029T
Other languages
English (en)
Inventor
Vincent Lenaerts
Francois Chouinard
Mircea A Mateescu
Pompilia Ispas-Szabo
Original Assignee
Vincent Lenaerts
Francois Chouinard
Mircea A Mateescu
Pompilia Ispas-Szabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vincent Lenaerts, Francois Chouinard, Mircea A Mateescu, Pompilia Ispas-Szabo filed Critical Vincent Lenaerts
Application granted granted Critical
Publication of ATE277604T1 publication Critical patent/ATE277604T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT99936029T 1998-02-24 1999-02-24 Quervernetzte stärke mit hohem amyloseanteil und funktionellen gruppen als matrix für langsame freisetzung pharmazeutischer wirkstoffe ATE277604T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/028,385 US6284273B1 (en) 1998-02-24 1998-02-24 Cross-linked high amylose starch resistant to amylase as a matrix for the slow release of biologically active compounds
PCT/CA1999/000169 WO1999043305A1 (en) 1998-02-24 1999-02-24 Cross-linked high amylose starch having functional groups as a matrix for the slow release of pharmaceutical agents

Publications (1)

Publication Number Publication Date
ATE277604T1 true ATE277604T1 (de) 2004-10-15

Family

ID=21843160

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99936029T ATE277604T1 (de) 1998-02-24 1999-02-24 Quervernetzte stärke mit hohem amyloseanteil und funktionellen gruppen als matrix für langsame freisetzung pharmazeutischer wirkstoffe

Country Status (19)

Country Link
US (2) US6284273B1 (de)
EP (1) EP1059915B1 (de)
JP (1) JP2002504508A (de)
KR (1) KR100713702B1 (de)
CN (1) CN1298297A (de)
AT (1) ATE277604T1 (de)
AU (1) AU755069B2 (de)
BR (1) BR9908187A (de)
CA (1) CA2321461C (de)
CZ (1) CZ301010B6 (de)
DE (1) DE69920669T2 (de)
HU (1) HU225045B1 (de)
IL (1) IL137955A (de)
NO (1) NO329257B1 (de)
NZ (1) NZ506437A (de)
PL (1) PL192468B1 (de)
PT (1) PT1059915E (de)
TR (1) TR200003014T2 (de)
WO (1) WO1999043305A1 (de)

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DE19927688A1 (de) * 1999-06-17 2000-12-21 Gruenenthal Gmbh Mehrschichttablette zur Verabreichung einer fixen Kombination von Tramadol und Diclofenac
US6607748B1 (en) * 2000-06-29 2003-08-19 Vincent Lenaerts Cross-linked high amylose starch for use in controlled-release pharmaceutical formulations and processes for its manufacture
US6777000B2 (en) 2001-02-28 2004-08-17 Carrington Laboratories, Inc. In-situ gel formation of pectin
US7494669B2 (en) 2001-02-28 2009-02-24 Carrington Laboratories, Inc. Delivery of physiological agents with in-situ gels comprising anionic polysaccharides
WO2002088331A1 (en) * 2001-05-01 2002-11-07 Universite Du Quebec A Montreal Tridimensional biocompatible support structure for bioartificial organs and uses thereof
US8487002B2 (en) * 2002-10-25 2013-07-16 Paladin Labs Inc. Controlled-release compositions
TWI319713B (en) * 2002-10-25 2010-01-21 Sustained-release tramadol formulations with 24-hour efficacy
PT1558935E (pt) * 2002-10-25 2008-10-16 Labopharm Inc Composições de libertação controlada
US20060172006A1 (en) * 2003-10-10 2006-08-03 Vincent Lenaerts Sustained-release tramadol formulations with 24-hour clinical efficacy
CA2547843A1 (en) * 2004-02-09 2005-08-18 Transfert Plus Societe En Commandite Composition comprising polymeric material and uses thereof
CA2491665A1 (fr) * 2004-12-24 2006-06-24 Louis Cartilier Formulation de comprime pour liberation soutenue de principe actif
ES2620293T3 (es) * 2005-09-09 2017-06-28 Paladin Labs Inc. Composición de liberación sostenida de fármacos
CN101252932B (zh) 2005-09-09 2012-10-03 安吉利尼莱博法姆有限责任公司 用于一天给药一次的曲唑酮组合物
ATE543522T1 (de) * 2005-09-21 2012-02-15 Surmodics Inc In vivo geformte matrizen mit natürlichen biologisch abbaubaren polysacchariden und ihre ophthalmischen verwendungen
CN101309709A (zh) * 2005-09-21 2008-11-19 苏尔莫迪克斯公司 包含天然生物可降解的多糖的涂层和物品
WO2007105719A1 (ja) * 2006-03-14 2007-09-20 National University Corporation NARA Institute of Science and Technology 新規なヘパリン代替材料およびその製造方法
CA2590821A1 (en) * 2007-06-07 2008-12-07 Universite De Montreal High-amylose sodium carboxymethyl starch sustained release excipient and process for preparing the same
CA2678092C (en) * 2007-10-16 2013-07-30 Labopharm Inc. Bilayer composition for the sustained release of acetaminophen and tramadol
CN101161684B (zh) * 2007-11-23 2010-05-19 华南理工大学 交联羧甲基淀粉的红外线合成方法
CA2707980C (en) * 2007-12-17 2015-05-12 Labopharm Inc. Misuse preventative, controlled release formulation
RU2491301C2 (ru) * 2007-12-21 2013-08-27 Акцо Нобель Н.В. Термореактивные полимеры
JP5763525B2 (ja) 2008-05-07 2015-08-12 サーモディクス，インコーポレイティド 粒子からの核酸複合体の送達
EP2331629B1 (de) * 2008-09-15 2016-06-22 Paladin Labs Inc. Auf stärke basierende mikropartikel zur freisetzung von darin enthaltenen wirkstoffen
EP2367541B1 (de) 2008-12-16 2014-07-16 Paladin Labs Inc. Formulierung mit gesteuerter freisetzung und missbrauchsschutz
EP2590636A1 (de) 2010-07-06 2013-05-15 Grünenthal GmbH Neue gastroretentive dosierungsformen mit einem gaba-analog und einem opioid
US8901092B2 (en) 2010-12-29 2014-12-02 Surmodics, Inc. Functionalized polysaccharides for active agent delivery
WO2012116434A1 (en) * 2011-03-01 2012-09-07 4413261 Canada Inc. (Spencer Canada) Two speed monolithic system for controlled release of drugs
JP6605508B2 (ja) * 2014-02-27 2019-11-13 ビー‐オーガニック フィルムス コーポレイション 一重らせんｖ構造を有する官能化デンプン中に含まれる生物活性剤
KR20170093243A (ko) 2014-12-19 2017-08-14 백스터 인터내셔널 인코포레이티드 유동성 지혈 조성물
CN104784738B (zh) * 2015-04-03 2016-12-07 四川大学 一种天然缓释多效医用海绵
CN106279453B (zh) * 2015-05-28 2019-12-10 易媛 交联的高分子化合物及其制备方法、水凝胶、水基压裂液和用途
CN105536058A (zh) * 2016-01-22 2016-05-04 青岛中腾生物技术有限公司 一种医用淀粉海绵及其制备方法和用途
GB2567493B (en) 2017-10-13 2019-12-18 Altus Formulation Inc Starch-based release modifying excipients and pharmaceutical compositions derived therefrom
CN111072791A (zh) * 2019-12-27 2020-04-28 河南新孚望新材料科技有限公司 一种包膜剂用高直链淀粉的制备方法
JP7125216B1 (ja) 2021-03-31 2022-08-24 長瀬産業株式会社 水溶性ポリマーの製造方法、および吸水性樹脂の製造方法
AU2022251740B2 (en) * 2021-03-31 2026-02-26 Nagase & Co., Ltd. Method for producing water-soluble polymer and method for producing water-absorbing resin
WO2025194276A1 (en) * 2024-03-21 2025-09-25 Eric Therasse Pharmaceutical composition comprising microparticles for high drug loading
CN119264282A (zh) * 2024-10-18 2025-01-07 华南理工大学 一种高空腔纳米淀粉及基于其的高耐老化橡胶材料与制备

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US4072535A (en) * 1970-12-28 1978-02-07 A. E. Staley Manufacturing Company Precompacted-starch binder-disintegrant-filler material for direct compression tablets and dry dosage capsules
US4369308A (en) * 1981-07-24 1983-01-18 National Starch And Chemical Corporation Low swelling starches as tablet disintegrants
JPH0791240B2 (ja) * 1987-04-01 1995-10-04 株式会社日本触媒 ２−ハロエチルアミンハロゲン化水素酸塩の製造方法
CA2041774C (en) * 1990-11-27 1994-04-19 Mircea A. Mateescu Use of cross-linked amylose as a matrix for the slow release of biologically active compounds
JPH06271704A (ja) * 1993-03-22 1994-09-27 Asahi Chem Ind Co Ltd 水性易燃性組成物
US5616343A (en) * 1993-03-25 1997-04-01 Labopharm, Inc. Cross-linked amylose as a binder/disintegrant in tablets
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US5593503A (en) * 1995-06-07 1997-01-14 National Starch And Chemical Investment Holding Corporation Process for producing amylase resistant granular starch
US5667637A (en) * 1995-11-03 1997-09-16 Weyerhaeuser Company Paper and paper-like products including water insoluble fibrous carboxyalkyl cellulose
CA2173818A1 (fr) * 1996-04-10 1997-10-11 Francois Chouinard Comprime pharmaceutique a liberation controlee contenant un support a base d'amylose reticule et d'hydroxypropylmethylcellulose
US5879707A (en) * 1996-10-30 1999-03-09 Universite De Montreal Substituted amylose as a matrix for sustained drug release
US5807575A (en) * 1997-02-14 1998-09-15 Rougier Inc. Manufacture of cross-linked amylose useful as a excipient for control release of active compounds

Also Published As

Publication number Publication date
NZ506437A (en) 2003-03-28
KR100713702B1 (ko) 2007-05-02
HUP0100818A2 (hu) 2001-08-28
KR20010034531A (ko) 2001-04-25
US6419957B1 (en) 2002-07-16
HUP0100818A3 (en) 2001-12-28
PL192468B1 (pl) 2006-10-31
EP1059915A1 (de) 2000-12-20
JP2002504508A (ja) 2002-02-12
US6284273B1 (en) 2001-09-04
DE69920669T2 (de) 2005-11-03
CN1298297A (zh) 2001-06-06
HU225045B1 (en) 2006-05-29
CZ20003097A3 (en) 2001-06-13
CA2321461C (en) 2008-04-29
WO1999043305A1 (en) 1999-09-02
CZ301010B6 (cs) 2009-10-14
TR200003014T2 (tr) 2001-02-21
AU755069B2 (en) 2002-12-05
NO20004208D0 (no) 2000-08-23
DE69920669D1 (de) 2004-11-04
NO20004208L (no) 2000-08-23
PT1059915E (pt) 2005-02-28
EP1059915B1 (de) 2004-09-29
BR9908187A (pt) 2000-10-31
PL342596A1 (en) 2001-06-18
CA2321461A1 (en) 1999-09-02
AU3242099A (en) 1999-09-15
IL137955A (en) 2005-12-18
IL137955A0 (en) 2001-10-31
NO329257B1 (no) 2010-09-20

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties