ATE282031T1 - Verfahren zur herstellung von citalopram - Google Patents

Verfahren zur herstellung von citalopram

Info

Publication number: ATE282031T1
Authority: AT; Austria
Prior art keywords: producing citalopram; citalopram; producing
Prior art date: 2000-03-13

Application number

AT01913728T

Other languages

English (en)

Inventor

Hans Petersen

Original Assignee

Lundbeck & Co As H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-13

Filing date

2001-03-07

Publication date

2004-11-15

2001-03-07 Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H

2004-11-15 Application granted granted Critical

2004-11-15 Publication of ATE282031T1 publication Critical patent/ATE282031T1/de

Links

WSEQXVZVJXJVFP-UHFFFAOYSA-N 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile Chemical compound O1CC2=CC(C#N)=CC=C2C1(CCCN(C)C)C1=CC=C(F)C=C1 WSEQXVZVJXJVFP-UHFFFAOYSA-N 0.000 title 1
229960001653 citalopram Drugs 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Neurosurgery (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Steroid Compounds (AREA)
Furan Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT01913728T 2000-03-13 2001-03-07 Verfahren zur herstellung von citalopram ATE282031T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DKPA200000404		2000-03-13
PCT/DK2001/000149 WO2001068628A1 (en)	2000-03-13	2001-03-07	Method for the preparation of citalopram

Publications (1)

Publication Number	Publication Date
ATE282031T1 true ATE282031T1 (de)	2004-11-15

Family

ID=8159323

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01913728T ATE282031T1 (de)	2000-03-13	2001-03-07	Verfahren zur herstellung von citalopram

Country Status (31)

Country	Link
US (1)	US6717000B2 (de)
EP (1)	EP1265880B1 (de)
JP (1)	JP2003527384A (de)
KR (1)	KR20020080471A (de)
CN (1)	CN1423644A (de)
AR (1)	AR029893A1 (de)
AT (1)	ATE282031T1 (de)
AU (1)	AU3920301A (de)
BE (1)	BE1011598A6 (de)
BG (1)	BG107048A (de)
BR (1)	BR0109267A (de)
CA (1)	CA2402386A1 (de)
CZ (1)	CZ20023383A3 (de)
DE (1)	DE60107061D1 (de)
EA (1)	EA200200971A1 (de)
FR (1)	FR2806085B1 (de)
HR (1)	HRP20020741A2 (de)
HU (1)	HUP0300180A2 (de)
IE (1)	IES20010206A2 (de)
IL (1)	IL151489A0 (de)
IS (1)	IS6528A (de)
IT (1)	ITMI20010487A1 (de)
MX (1)	MXPA02008872A (de)
NL (1)	NL1017500C1 (de)
NO (1)	NO20024214L (de)
NZ (1)	NZ521202A (de)
PL (1)	PL360108A1 (de)
SK (1)	SK14592002A3 (de)
TR (1)	TR200202167T2 (de)
WO (1)	WO2001068628A1 (de)
ZA (1)	ZA200206898B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NZ514671A (en)	1999-04-14	2003-10-31	H	Method for the preparation of citalopram
NL1017417C1 (nl)	2000-03-03	2001-03-16	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
KR20020080481A (ko)	2000-03-13	2002-10-23	하. 룬트벡 아크티에 셀스카브	시탈로프람의 제조 방법
CZ20023100A3 (cs) *	2000-03-13	2003-02-12	H. Lundbeck A/S	Způsob výroby citalopramu
SK14512002A3 (sk)	2000-03-14	2003-03-04	H. Lundbeck A/S	Spôsob výroby citalopramu, medziprodukt a citalopram výrobený týmto spôsobom
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
TR200504022T1 (tr) *	2003-03-24	2006-08-21	Hetero Drugs Limited	(S)-sitalopram oksalatın yeni sıvı kristal formları.
CN100569765C (zh)	2003-12-19	2009-12-16	杭州民生药业集团有限公司	西酞普兰中间体晶体碱

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1143703A (de)	1965-03-18
GB1526331A (en)	1976-01-14	1978-09-27	Kefalas As	Phthalanes
GB8419963D0 (en)	1984-08-06	1984-09-12	Lundbeck & Co As H	Intermediate compound and method
GB8814057D0 (en)	1988-06-14	1988-07-20	Lundbeck & Co As H	New enantiomers & their isolation
US5296507A (en)	1990-09-06	1994-03-22	H.Lundbeck A/S	Treatment of cerbrovascular disorders
DE19626659A1 (de)	1996-07-03	1998-01-08	Basf Ag	Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de)	1996-07-10	1998-01-15	Basf Ag	Verfahren zur Herstellung von Phthaliden
TR200000066T2 (tr)	1997-07-08	2000-11-21	H. Lundbeck A/S	Sitalopram hazırlanması için yöntem.
UA62985C2 (en) *	1997-11-10	2004-01-15	Lunnbeck As H	A method for the preparation of citalopram
ES2149734T3 (es)	1997-11-11	2003-02-16	Lundbeck & Co As H	Metodo para la preparacion de citalopram.
PL199423B1 (pl)	1998-10-20	2008-09-30	Lundbeck & Co As H	Sposób wytwarzania citalopramu
CN1149208C (zh)	1998-12-23	2004-05-12	H.隆德贝克有限公司	制备5-氰基2-苯并[c]呋喃酮的方法
AR022329A1 (es)	1999-01-29	2002-09-04	Lundbeck & Co As H	Metodo para la preparacion de 5-cianoftalida
NZ514671A (en)	1999-04-14	2003-10-31	H	Method for the preparation of citalopram
ITMI991581A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
ITMI991579A1 (it)	1999-06-25	2001-01-15	Lundbeck & Co As H	Metodo per la preparazione di citalopram
CH692298A5 (de)	1999-10-25	2002-04-30	Lundbeck & Co As H	Verfahren zur Herstellung von Zwischenstufen für die Citalopramsynthese sowie zur Herstellung von Escitalopram.
AR026063A1 (es)	1999-11-01	2002-12-26	Lundbeck & Co As H	Metodo para la preparacion de 5-carboxiftalida.
US6310222B1 (en)	1999-11-01	2001-10-30	Sumika Fine Chemicals Co., Ltd.	Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
EA004742B1 (ru)	1999-12-28	2004-08-26	Х.Лундбекк А/С	Способ получения циталопрама
WO2001049672A1 (en)	1999-12-30	2001-07-12	H. Lundbeck A/S	Method for the preparation of citalopram
TR200201783T2 (tr)	2000-01-14	2002-12-23	H. Lundbeck A/S	5-Siyanofatalid hazırlamak için yöntem
US6433196B1 (en)	2000-02-17	2002-08-13	Sumika Fine Chemicals Co., Ltd.	Production method of citalopram, intermediate therefor and production method of the intermediate
IES20010143A2 (en)	2000-02-24	2001-07-25	Lundbeck & Co As H	Method for the preparation of citalopram
NL1017415C1 (nl)	2000-02-24	2001-05-18	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl)	2000-03-03	2001-03-16	Lundbeck & Co As H	Werkwijze voor de bereiding van Citalopram.
GB0005477D0 (en)	2000-03-07	2000-04-26	Resolution Chemicals Limited	Process for the preparation of citalopram
KR20020080481A (ko)	2000-03-13	2002-10-23	하. 룬트벡 아크티에 셀스카브	시탈로프람의 제조 방법
GB2357762B (en)	2000-03-13	2002-01-30	Lundbeck & Co As H	Crystalline base of citalopram
CZ20023100A3 (cs)	2000-03-13	2003-02-12	H. Lundbeck A/S	Způsob výroby citalopramu
SK14512002A3 (sk)	2000-03-14	2003-03-04	H. Lundbeck A/S	Spôsob výroby citalopramu, medziprodukt a citalopram výrobený týmto spôsobom
EP1274699A1 (de)	2000-03-16	2003-01-15	H. Lundbeck A/S	Verfahren zur herstellung von 5-cyano-1-(4-fluorophenyl)-1,3-dihydroisobenzofuranen
AR032455A1 (es)	2000-05-12	2003-11-12	Lundbeck & Co As H	Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
BR0106976A (pt)	2000-07-06	2002-07-23	Lundbeck & Co As H	Método para a preparação de citalopram
IL144817A0 (en)	2000-08-18	2002-06-30	Lundbeck & Co As H	Method for the preparation of citalopram
JP3798982B2 (ja)	2000-12-22	2006-07-19	ハー・ルンドベック・アクチエゼルスカベット	純粋なシタロプラムの製造方法
CA2359810C (en)	2000-12-28	2002-11-05	H. Lundbeck A/S	Process for the preparation of pure citalopram

2001
- 2001-03-05 NL NL1017500A patent/NL1017500C1/nl not_active IP Right Cessation
- 2001-03-05 IE IE20010206A patent/IES20010206A2/en not_active IP Right Cessation
- 2001-03-07 HR HR20020741A patent/HRP20020741A2/hr not_active Application Discontinuation
- 2001-03-07 EA EA200200971A patent/EA200200971A1/ru unknown
- 2001-03-07 AU AU39203/01A patent/AU3920301A/en not_active Abandoned
- 2001-03-07 BR BR0109267-7A patent/BR0109267A/pt not_active IP Right Cessation
- 2001-03-07 CZ CZ20023383A patent/CZ20023383A3/cs unknown
- 2001-03-07 NZ NZ521202A patent/NZ521202A/en unknown
- 2001-03-07 WO PCT/DK2001/000149 patent/WO2001068628A1/en not_active Ceased
- 2001-03-07 AT AT01913728T patent/ATE282031T1/de not_active IP Right Cessation
- 2001-03-07 IL IL15148901A patent/IL151489A0/xx unknown
- 2001-03-07 JP JP2001567720A patent/JP2003527384A/ja not_active Withdrawn
- 2001-03-07 DE DE60107061T patent/DE60107061D1/de not_active Expired - Lifetime
- 2001-03-07 CA CA002402386A patent/CA2402386A1/en not_active Abandoned
- 2001-03-07 SK SK1459-2002A patent/SK14592002A3/sk unknown
- 2001-03-07 AR ARP010101064A patent/AR029893A1/es unknown
- 2001-03-07 CN CN01806481A patent/CN1423644A/zh active Pending
- 2001-03-07 PL PL36010801A patent/PL360108A1/xx not_active Application Discontinuation
- 2001-03-07 TR TR2002/02167T patent/TR200202167T2/xx unknown
- 2001-03-07 HU HU0300180A patent/HUP0300180A2/hu unknown
- 2001-03-07 KR KR1020027011671A patent/KR20020080471A/ko not_active Withdrawn
- 2001-03-07 MX MXPA02008872A patent/MXPA02008872A/es unknown
- 2001-03-07 EP EP01913728A patent/EP1265880B1/de not_active Expired - Lifetime
- 2001-03-08 IT IT2001MI000487A patent/ITMI20010487A1/it unknown
- 2001-03-09 FR FR0103245A patent/FR2806085B1/fr not_active Expired - Fee Related
- 2001-03-13 BE BE2001/0159A patent/BE1011598A6/fr not_active IP Right Cessation
2002
- 2002-08-27 IS IS6528A patent/IS6528A/is unknown
- 2002-08-28 ZA ZA200206898A patent/ZA200206898B/en unknown
- 2002-09-02 BG BG107048A patent/BG107048A/xx unknown
- 2002-09-04 NO NO20024214A patent/NO20024214L/no not_active Application Discontinuation
- 2002-09-09 US US10/238,843 patent/US6717000B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
TR200202167T2 (tr)	2002-12-23
EP1265880B1 (de)	2004-11-10
NO20024214L (no)	2002-10-31
IS6528A (is)	2002-08-27
JP2003527384A (ja)	2003-09-16
US6717000B2 (en)	2004-04-06
BG107048A (en)	2003-05-30
ZA200206898B (en)	2004-04-20
HRP20020741A2 (en)	2003-12-31
AR029893A1 (es)	2003-07-23
EP1265880A1 (de)	2002-12-18
NO20024214D0 (no)	2002-09-04
CZ20023383A3 (cs)	2003-01-15
IL151489A0 (en)	2003-04-10
KR20020080471A (ko)	2002-10-23
BR0109267A (pt)	2002-12-17
WO2001068628A1 (en)	2001-09-20
CN1423644A (zh)	2003-06-11
HUP0300180A2 (en)	2003-05-28
EA200200971A1 (ru)	2003-02-27
DE60107061D1 (de)	2004-12-16
BE1011598A6 (fr)	2001-07-03
AU3920301A (en)	2001-09-24
IES20010206A2 (en)	2002-03-06
SK14592002A3 (sk)	2003-03-04
PL360108A1 (en)	2004-09-06
ITMI20010487A1 (it)	2002-09-08
CA2402386A1 (en)	2001-09-20
FR2806085A1 (fr)	2001-09-14
MXPA02008872A (es)	2003-02-10
NZ521202A (en)	2004-11-26
US20030069304A1 (en)	2003-04-10
FR2806085B1 (fr)	2005-02-25
NL1017500C1 (nl)	2001-04-26

Legal Events

Date	Code	Title	Description
2005-05-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DE69907037D1 (de)	2003-05-22	Verfahren zur herstellung von citalopram
DE69900891D1 (de)	2002-03-21	Verfahren zur herstellung von citalopram
ATE235478T1 (de)	2003-04-15	Verfahren zur herstellung von citalopram
ATE281448T1 (de)	2004-11-15	Verfahren zur herstellung von citalopram
DE60100016D1 (de)	2002-10-02	Verfahren zur herstellung von reinem citalopram
DE69904853D1 (de)	2003-02-13	Verfahren zur herstellung von citalopram
ATE386736T1 (de)	2008-03-15	Verfahren zur herstellung von benzimidazol-2-yl - chinolinonderivaten
AT7110U9 (de)	2004-11-25	Verfahren zur herstellung von amlodipinmaleat
ATE222900T1 (de)	2002-09-15	Verfahren zur herstellung von 5-cyanophthalid
ATE277920T1 (de)	2004-10-15	Verfahren zur vorbereitung von reinem citalopram
ATE232524T1 (de)	2003-02-15	Verfahren zur herstellung von citalopram
ATE331804T1 (de)	2006-07-15	Verfahren zur herstellung von ansamitocin
DE60003264D1 (de)	2003-07-17	Verfahren zur herstellung von glycerylethern
DE50102444D1 (de)	2004-07-01	Verfahren zur herstellung von isocyanatoorganosilanen
ATE316518T1 (de)	2006-02-15	Verfahren zur herstellung von (r)-2-alkyl-3- phenyl-1-propanolen
DE50111560D1 (de)	2007-01-11	Verfahren zur herstellung von guerbetalkoholen
DE60103173D1 (de)	2004-06-09	Verfahren zur herstellung von 3-amino-2-chlor-4-methylpyridin
ATE389645T1 (de)	2008-04-15	Verfahren zur herstellung von citalopram
DE50006772D1 (de)	2004-07-15	Verfahren zur herstellung von oxindolen
ATE355268T1 (de)	2006-03-15	Verfahren zur herstellung von citalopram
DE60105991D1 (de)	2004-11-04	Verfahren zur herstellung von 6-aminocapronamid
DE60107061D1 (de)	2004-12-16	Verfahren zur herstellung von citalopram
ATE232845T1 (de)	2003-03-15	Verfahren zur herstellung von cyclopropenen
DE50001895D1 (de)	2003-05-28	Verfahren zur herstellung von phosphonomethylglycin
ATE325810T1 (de)	2006-06-15	Verfahren zur herstellung von acetylamidiniophenylalanyl-cyclohexylglycyl- pyridylalaninamiden