ATE283277T1 - Verfahren zur entfernung von viren aus proteinlösungen mittels nanofiltration - Google Patents

Verfahren zur entfernung von viren aus proteinlösungen mittels nanofiltration

Info

Publication number
ATE283277T1
ATE283277T1 AT98908308T AT98908308T ATE283277T1 AT E283277 T1 ATE283277 T1 AT E283277T1 AT 98908308 T AT98908308 T AT 98908308T AT 98908308 T AT98908308 T AT 98908308T AT E283277 T1 ATE283277 T1 AT E283277T1
Authority
AT
Austria
Prior art keywords
viruses
nanofiltration
removal
log
protein solutions
Prior art date
Application number
AT98908308T
Other languages
English (en)
Inventor
Harry Hiemstra
Hart Hendricus Gerardus Jo Ter
Nijs Ingrid Margareth Prins-De
Pieter Johannes Hoek
Jan Over
Original Assignee
Sanquin Bloedvoorziening
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26146172&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE283277(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanquin Bloedvoorziening filed Critical Sanquin Bloedvoorziening
Application granted granted Critical
Publication of ATE283277T1 publication Critical patent/ATE283277T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Water Supply & Treatment (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT98908308T 1997-02-24 1998-02-23 Verfahren zur entfernung von viren aus proteinlösungen mittels nanofiltration ATE283277T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL1005332 1997-02-24
EP97200533A EP0860444A1 (de) 1997-02-24 1997-02-24 Methode zur Entfernung von Viren aus Proteinlösungen
PCT/NL1998/000108 WO1998037086A1 (en) 1997-02-24 1998-02-23 Method for removing viruses from protein solution by nanofiltration

Publications (1)

Publication Number Publication Date
ATE283277T1 true ATE283277T1 (de) 2004-12-15

Family

ID=26146172

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98908308T ATE283277T1 (de) 1997-02-24 1998-02-23 Verfahren zur entfernung von viren aus proteinlösungen mittels nanofiltration

Country Status (6)

Country Link
EP (2) EP0860444A1 (de)
AT (1) ATE283277T1 (de)
DE (1) DE69827787T2 (de)
DK (1) DK0979237T3 (de)
ES (1) ES2229481T3 (de)
WO (1) WO1998037086A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2772381B1 (fr) * 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
US6355243B1 (en) 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US7544500B2 (en) * 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
US6867285B2 (en) * 1999-12-20 2005-03-15 Mitsubishi Pharma Corporation Virus-free plasma protein compositions treated with porous membrane and process for producing the same
ES2214967B1 (es) 2003-03-06 2005-06-16 Probitas Pharma, S.A Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento.
WO2004089402A1 (ja) * 2003-04-09 2004-10-21 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute アルブミン製剤の製造方法
FR2861395B1 (fr) 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
AU2012201036B2 (en) * 2003-12-01 2014-12-04 Novo Nordisk Health Care Ag Virus filtration of liquid factor VII compositions
EP1711513B1 (de) 2003-12-01 2014-07-02 Novo Nordisk Health Care AG Nanofiltration von faktor vii lösungen zur entfernung von viren
WO2006042541A1 (en) * 2004-10-21 2006-04-27 Statens Serum Institut A method comprising nanofiltration to obtain an mbl product safe from infectious agents and the product obtainable by this method
ES2775974T3 (es) * 2006-06-26 2020-07-28 Omrix Biopharmaceuticals Inc Eliminación de virus por nanofiltración
ES2298096B1 (es) 2008-01-08 2009-01-01 Grifols, S.A. Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.
NZ589557A (en) 2008-06-04 2012-08-31 Talecris Biotherapeutics Inc Immobilised streptokinase, method and kit for preparing plasmin
US8158405B2 (en) 2008-06-30 2012-04-17 General Electric Company Process for concentrating and processing fluid samples
US8546127B2 (en) 2008-06-30 2013-10-01 General Electric Company Bacteria/RNA extraction device
ES2552337T3 (es) 2009-03-03 2015-11-27 Grifols Therapeutics Inc. Procedimientos para la preparación de plasminógeno
WO2013036445A1 (en) * 2011-09-06 2013-03-14 Medimmune Llc Methods for processing coagulation factors
CN112978859A (zh) * 2021-04-13 2021-06-18 莱特莱德(上海)技术有限公司 一种提取肝素加工废水中肠膜肽的方法
CN116983835B (zh) * 2023-09-28 2024-01-09 杭州华玮生物科技有限公司 一种高强度纤维素除病毒过滤膜及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9500724D0 (sv) * 1994-06-23 1995-02-24 Pharmacia Ab Filtrering
US5677162A (en) * 1995-05-01 1997-10-14 New York Blood Center, Inc. Method for activating prothrombin to thrombin

Also Published As

Publication number Publication date
DE69827787T2 (de) 2006-03-02
EP0979237A1 (de) 2000-02-16
WO1998037086A1 (en) 1998-08-27
EP0860444A1 (de) 1998-08-26
EP0979237B1 (de) 2004-11-24
DK0979237T3 (da) 2005-04-04
DE69827787D1 (de) 2004-12-30
ES2229481T3 (es) 2005-04-16

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