DK0979237T3 - Fremgangsmåde til fjernelse af virus fra proteinoplösning ved nanofiltrering - Google Patents

Fremgangsmåde til fjernelse af virus fra proteinoplösning ved nanofiltrering

Info

Publication number
DK0979237T3
DK0979237T3 DK98908308T DK98908308T DK0979237T3 DK 0979237 T3 DK0979237 T3 DK 0979237T3 DK 98908308 T DK98908308 T DK 98908308T DK 98908308 T DK98908308 T DK 98908308T DK 0979237 T3 DK0979237 T3 DK 0979237T3
Authority
DK
Denmark
Prior art keywords
nanofiltration
protein solution
log
removing virus
virus
Prior art date
Application number
DK98908308T
Other languages
Danish (da)
English (en)
Inventor
Harry Hiemstra
Hart Hendricus Gerardus Jo Ter
Nijs Ingrid Margareth Prins-De
Pieter Johannes Hoek
Jan Over
Original Assignee
Sanquin Bloedvoorziening
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26146172&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0979237(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Sanquin Bloedvoorziening filed Critical Sanquin Bloedvoorziening
Application granted granted Critical
Publication of DK0979237T3 publication Critical patent/DK0979237T3/da

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/145—Ultrafiltration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6429—Thrombin (3.4.21.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21005—Thrombin (3.4.21.5)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Water Supply & Treatment (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
DK98908308T 1997-02-24 1998-02-23 Fremgangsmåde til fjernelse af virus fra proteinoplösning ved nanofiltrering DK0979237T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP97200533A EP0860444A1 (de) 1997-02-24 1997-02-24 Methode zur Entfernung von Viren aus Proteinlösungen
NL1005332 1997-02-24
EP98908308A EP0979237B1 (de) 1997-02-24 1998-02-23 Verfahren zur entfernung von viren aus proteinlösungen mittels nanofiltration
PCT/NL1998/000108 WO1998037086A1 (en) 1997-02-24 1998-02-23 Method for removing viruses from protein solution by nanofiltration

Publications (1)

Publication Number Publication Date
DK0979237T3 true DK0979237T3 (da) 2005-04-04

Family

ID=26146172

Family Applications (1)

Application Number Title Priority Date Filing Date
DK98908308T DK0979237T3 (da) 1997-02-24 1998-02-23 Fremgangsmåde til fjernelse af virus fra proteinoplösning ved nanofiltrering

Country Status (6)

Country Link
EP (2) EP0860444A1 (de)
AT (1) ATE283277T1 (de)
DE (1) DE69827787T2 (de)
DK (1) DK0979237T3 (de)
ES (1) ES2229481T3 (de)
WO (1) WO1998037086A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2772381B1 (fr) † 1997-12-15 2001-06-08 Lab Francais Du Fractionnement Procede de preparation par filtration d'une solution de facteur viii securisee viralement
US6355243B1 (en) 1999-11-13 2002-03-12 Bayer Corporation Method of thrombolysis by local delivery of active plasmin
US7544500B2 (en) * 1999-11-13 2009-06-09 Talecris Biotherapeutics, Inc. Process for the production of a reversibly inactive acidified plasmin composition
KR20020063597A (ko) * 1999-12-20 2002-08-03 미츠비시 웰파마 가부시키가이샤 다공성막으로 처리되어 바이러스가 제거된 혈장 단백질조성물 및 그 제조 방법
ES2214967B1 (es) 2003-03-06 2005-06-16 Probitas Pharma, S.A Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento.
US8258264B2 (en) 2003-04-09 2012-09-04 Juridical Foundation The Chemo-Sero-Therapeutic Research Institute Process for producing albumin preparation
FR2861395B1 (fr) * 2003-10-23 2006-02-17 Lab Francais Du Fractionnement Facteur viii viralement securise a faible teneur en multimeres superieurs
CN106916802B (zh) 2003-12-01 2022-03-25 诺和诺德医疗保健公司 液体因子vii组合物的病毒过滤
AU2012201036B2 (en) * 2003-12-01 2014-12-04 Novo Nordisk Health Care Ag Virus filtration of liquid factor VII compositions
US7776821B2 (en) * 2004-10-21 2010-08-17 Statens Serum Institut Method comprising nanofiltration to obtain an MBL product safe from infectious agents and the product obtainable by this method
ES2775974T3 (es) * 2006-06-26 2020-07-28 Omrix Biopharmaceuticals Inc Eliminación de virus por nanofiltración
ES2298096B1 (es) * 2008-01-08 2009-01-01 Grifols, S.A. Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos.
NZ589557A (en) 2008-06-04 2012-08-31 Talecris Biotherapeutics Inc Immobilised streptokinase, method and kit for preparing plasmin
US8158405B2 (en) 2008-06-30 2012-04-17 General Electric Company Process for concentrating and processing fluid samples
US8546127B2 (en) 2008-06-30 2013-10-01 General Electric Company Bacteria/RNA extraction device
HUE025670T2 (en) 2009-03-03 2016-04-28 Grifols Therapeutics Inc A method for producing plasminogen
CA2847818A1 (en) 2011-09-06 2013-03-14 Medimmune, Llc Methods for processing coagulation factors
CN112978859A (zh) * 2021-04-13 2021-06-18 莱特莱德(上海)技术有限公司 一种提取肝素加工废水中肠膜肽的方法
CN116983835B (zh) * 2023-09-28 2024-01-09 杭州华玮生物科技有限公司 一种高强度纤维素除病毒过滤膜及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9500724D0 (sv) * 1994-06-23 1995-02-24 Pharmacia Ab Filtrering
US5677162A (en) * 1995-05-01 1997-10-14 New York Blood Center, Inc. Method for activating prothrombin to thrombin

Also Published As

Publication number Publication date
EP0979237A1 (de) 2000-02-16
ATE283277T1 (de) 2004-12-15
ES2229481T3 (es) 2005-04-16
EP0860444A1 (de) 1998-08-26
DE69827787D1 (de) 2004-12-30
EP0979237B1 (de) 2004-11-24
WO1998037086A1 (en) 1998-08-27
DE69827787T2 (de) 2006-03-02

Similar Documents

Publication Publication Date Title
DE69827787D1 (de) Verfahren zur entfernung von viren aus proteinlösungen mittels nanofiltration
ATE346861T1 (de) Verfahren zur reinigung und isolierung von viren, aus pflanzenquellen
DK0891420T3 (da) Fremgangsmåde til replikation af influenzavirus i cellekultur samt de ved fremgangsmåden opnåelige influenzavirus
DK164537C (da) Fremgangsmaade til inaktivering af hepatitis-b-virus eller non-a, non-b-hepatitisvirus i pattedyrsblodplasma eller pattedyrsplasmaproteinoploesninger
AU696246B2 (en) Process for the sterilization of biological compositions and the product produced thereby
AU5370598A (en) Methods for purifying viruses
SG156673A1 (en) Improved viral purification methods
JP4495404B2 (ja) ナノろ過によってタンパク溶液からウイルスを分離する方法
DE50109784D1 (de) Stabilisiertes Protein-Präparat und Verfahren zu seiner Herstellung
ATE257175T1 (de) Rekombinantes infektiöses nicht-in-segmente- geteiltes, negativ-strange-rns-virus
ES2101077T3 (es) Procedimiento para la inactivacion de priones.
DE69721840D1 (en) Zuckerrohr bacilliformviruspromotor
Schlegel et al. Virus inactivation of plasma‐derived proteins by pasteurization in the presence of guanidine hydrochloride
DK0480949T3 (da) Fremstilling af virus og oprensning af virale kappeproteiner til vaccineanvendelse
CA2169122A1 (en) Removal of viruses from protein solutions by ultrafiltration
JPH11286453A (ja) 紫外線照射によるタンパク質含有組成物のウイルス不活化処理方法
ES2196870T3 (es) Procedimiento para la purificacion o aislamiento de acidos nucleicos virales.
ATE414147T1 (de) Nukleinsäurereinigung
ATE179428T1 (de) Verfahren zur herstellung von hepatitis antigenen und impfstoffen
Van Holten et al. Incorporation of an additional viral‐clearance step into a human immunoglobulin manufacturing process
DE69125066D1 (de) cDNS-Sequenz und Detektion des Hepatitis C-Virus
DE59813486D1 (de) Verfahren zur Herstellung von Blutplasmaprodukten durch Ausschluss von Spenden mit hohen Parvo-B19-Virenkonzentrationen
CA2524246C (en) Process for producing albumin preparations comprising virus-removing filtration
US20040000482A1 (en) Viral removal
AU2003209815B2 (en) Recovery of viruses