ATE325108T1 - Pyrrolidin-derivate als inhibitoren von cyclischer amp-phosphodiesterase - Google Patents

Pyrrolidin-derivate als inhibitoren von cyclischer amp-phosphodiesterase

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Publication number
ATE325108T1
ATE325108T1 AT00987999T AT00987999T ATE325108T1 AT E325108 T1 ATE325108 T1 AT E325108T1 AT 00987999 T AT00987999 T AT 00987999T AT 00987999 T AT00987999 T AT 00987999T AT E325108 T1 ATE325108 T1 AT E325108T1
Authority
AT
Austria
Prior art keywords
cyclic amp
phosphodiesterase inhibitors
pyrrolidine derivatives
amp phosphodiesterase
disclosed
Prior art date
Application number
AT00987999T
Other languages
English (en)
Inventor
Timothy J Martins
Kerry W Fowler
Joshua Odingo
Edward A Kesicki
Amy Oliver
Laurence E Burgess
John J Gaudino
Zachary S Jones
Bradley J Newhouse
Stephen Schlachter
Original Assignee
Icos Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Icos Corp filed Critical Icos Corp
Application granted granted Critical
Publication of ATE325108T1 publication Critical patent/ATE325108T1/de

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    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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AT00987999T 1999-12-23 2000-11-28 Pyrrolidin-derivate als inhibitoren von cyclischer amp-phosphodiesterase ATE325108T1 (de)

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Application Number Priority Date Filing Date Title
US09/471,846 US6258833B1 (en) 1999-12-23 1999-12-23 Cyclic AMP-specific phosphodiesterase inhibitors

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ATE325108T1 true ATE325108T1 (de) 2006-06-15

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EP (1) EP1242400B1 (de)
JP (1) JP4294903B2 (de)
KR (1) KR20020063600A (de)
CN (1) CN1434813A (de)
AT (1) ATE325108T1 (de)
AU (1) AU778543B2 (de)
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