ATE346841T1 - Azabicyclo-verbindungen welche die inhibition der zell adhesion modulieren - Google Patents
Azabicyclo-verbindungen welche die inhibition der zell adhesion modulierenInfo
- Publication number
- ATE346841T1 ATE346841T1 AT99943058T AT99943058T ATE346841T1 AT E346841 T1 ATE346841 T1 AT E346841T1 AT 99943058 T AT99943058 T AT 99943058T AT 99943058 T AT99943058 T AT 99943058T AT E346841 T1 ATE346841 T1 AT E346841T1
- Authority
- AT
- Austria
- Prior art keywords
- ny4y5
- linkage
- alkyl
- modulate
- inhibition
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 2
- 230000023578 negative regulation of cell adhesion Effects 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 230000002378 acidificating effect Effects 0.000 abstract 2
- 125000000524 functional group Chemical group 0.000 abstract 2
- -1 imino, oxo, thioxo Chemical group 0.000 abstract 2
- 125000004450 alkenylene group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- 125000004419 alkynylene group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000000732 arylene group Chemical group 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000005724 cycloalkenylene group Chemical group 0.000 abstract 1
- 125000002993 cycloalkylene group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000004446 heteroarylalkyl group Chemical group 0.000 abstract 1
- 125000006588 heterocycloalkylene group Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004043 oxo group Chemical group O=* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/04—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms
- C07D215/08—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to the ring carbon atoms with acylated ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Secondary Cells (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Electroluminescent Light Sources (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9818641.4A GB9818641D0 (en) | 1998-08-26 | 1998-08-26 | Chemical compounds |
| US11000898P | 1998-11-25 | 1998-11-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE346841T1 true ATE346841T1 (de) | 2006-12-15 |
Family
ID=26314269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99943058T ATE346841T1 (de) | 1998-08-26 | 1999-08-26 | Azabicyclo-verbindungen welche die inhibition der zell adhesion modulieren |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6608084B1 (de) |
| EP (1) | EP1114028B1 (de) |
| KR (1) | KR20010085630A (de) |
| CN (1) | CN1323295A (de) |
| AT (1) | ATE346841T1 (de) |
| AU (1) | AU754557B2 (de) |
| BR (1) | BR9913222A (de) |
| CA (1) | CA2341677A1 (de) |
| DE (1) | DE69934238T2 (de) |
| DK (1) | DK1114028T3 (de) |
| ES (1) | ES2276530T3 (de) |
| HU (1) | HUP0104766A3 (de) |
| IL (2) | IL141596A0 (de) |
| MX (1) | MXPA01001995A (de) |
| NO (1) | NO20010942L (de) |
| NZ (1) | NZ509781A (de) |
| PL (1) | PL346248A1 (de) |
| PT (1) | PT1114028E (de) |
| SK (1) | SK2612001A3 (de) |
| TR (1) | TR200100588T2 (de) |
| WO (1) | WO2000015612A1 (de) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4591800A (en) * | 1999-05-05 | 2000-11-21 | Aventis Pharma Limited | Ureas as cell adhesion modulators |
| YU41202A (sh) | 1999-12-28 | 2005-03-15 | Pfizer Products Inc. | Ne-peptidni inhibitori vezivanja za ćeliju zavisnog od vla-4 korisni pri tretiranju inflamatornih, autoimunih i respiratornih bolesti |
| AU2001235806A1 (en) * | 2000-03-01 | 2001-09-12 | Aventis Pharma Limited | 2,3-dihydro-1h-indolinyl-alkanoic acids as cell adhesion inhibitors |
| EP1283199A4 (de) * | 2000-05-16 | 2003-12-17 | Takeda Chemical Industries Ltd | Antagonisten des melanin-konzentrierenden hormons |
| FR2812633A1 (fr) * | 2000-08-04 | 2002-02-08 | Aventis Cropscience Sa | Derives de phenyl(thio)urees et phenyl(thio)carbamates fongicides |
| CA2427750C (en) | 2000-11-04 | 2011-01-04 | Aventis Pharma Limited | Substituted alkanoic acids |
| CA2430978C (en) | 2000-12-28 | 2012-05-15 | Daiichi Pharmaceutical Co., Ltd. | Vla-4 inhibitors |
| JP4583751B2 (ja) * | 2001-06-06 | 2010-11-17 | アベンティス・フアーマ・リミテッド | 炎症性疾患の治療に使用するための置換されたテトラヒドロイソキノリン |
| US7557130B2 (en) | 2001-07-26 | 2009-07-07 | Ucb Pharma, S.A. | Bicyclic heteroaromatic alanines |
| WO2003093237A1 (en) * | 2002-04-30 | 2003-11-13 | Ucb, S.A. | 2,6-quinolinyl and 2,6-naphthyl derivatives, processes for preparing them and their uses as vla-4 inhibitors |
| BRPI0408248A (pt) | 2003-03-12 | 2006-03-01 | Pfizer Prod Inc | derivados azabicìclicos de piridiloximetila e de benzisoxazol |
| JP4676884B2 (ja) | 2003-07-24 | 2011-04-27 | 第一三共株式会社 | シクロヘキサンカルボン酸類 |
| CA2610800A1 (en) | 2005-06-09 | 2006-12-14 | Ucb Pharma, S.A. | 2,6 quinolinyl derivatives, processes for preparing them and their use as medicament |
| US7790745B2 (en) | 2005-10-21 | 2010-09-07 | Bristol-Myers Squibb Company | Tetrahydroisoquinoline LXR Modulators |
| US7741317B2 (en) * | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
| CN101360736A (zh) * | 2005-11-23 | 2009-02-04 | 阿斯利康(瑞典)有限公司 | L-丙氨酸衍生物 |
| JP2009539815A (ja) * | 2006-06-09 | 2009-11-19 | アストラゼネカ アクチボラグ | 固形腫瘍の治療用のａ５ｂ１アンタゴニストとしてのＮ−（ベンゾイル）−Ｏ−［２−（ピリジン−２−イルアミノ）エチル］−Ｌ−チロシン誘導体と関連化合物 |
| WO2008093065A1 (en) * | 2007-01-29 | 2008-08-07 | Astrazeneca Ab | L-ALANINE DERIVATIVES AS α5βL ANTAGONISTS |
| WO2008125811A1 (en) * | 2007-04-11 | 2008-10-23 | Astrazeneca Ab | N-[HETEROARYLCARBONYL]-S-THIENYL-L-ALANINE DERIVATIVES AS α5β1 ANTAGONISTS |
| UY32138A (es) | 2008-09-25 | 2010-04-30 | Boehringer Ingelheim Int | Amidas sustituidas del ácido 2-(2,6-dicloro-fenilamino)-6-fluoro-1-metil-1h-bencimidazol-5-carboxílico y sus sales farmacéuticamente aceptables |
| UY32470A (es) | 2009-03-05 | 2010-10-29 | Boehringer Ingelheim Int | Derivados de 2-{2-cloro-5-[(sustituido) metil]fenilamino} -1-metil]fenilamino}-1-metilbencimidazol-5-carboxamidas-n-(sustituidas) y sus sales fisiológicamente aceptables, composiciones conteniéndolos y aplicaciones |
| JP5732453B2 (ja) | 2009-06-25 | 2015-06-10 | アルカーメス ファーマ アイルランド リミテッド | Ｎｈ酸性化合物のプロドラッグ |
| PT2445502T (pt) | 2009-06-25 | 2017-09-22 | Alkermes Pharma Ireland Ltd | Compostos heterocíclicos para o tratamento de distúrbios neurológicos e psicológicos |
| EP2521545B1 (de) | 2010-01-07 | 2019-11-27 | Alkermes Pharma Ireland Limited | Prodrugs aus heteroaromatischen verbindungen |
| EP2521711B1 (de) * | 2010-01-07 | 2017-08-16 | Alkermes Pharma Ireland Limited | Quartäre ammoniumsalz-prodrugs |
| US20110166128A1 (en) * | 2010-01-07 | 2011-07-07 | Alkermes, Inc. | Diaryldiazepine Prodrugs for the Treatment of Neurological and Psychological Disorders |
| WO2011084851A1 (en) * | 2010-01-07 | 2011-07-14 | Alkermes, Inc. | Asenapine produrugs |
| WO2011084850A1 (en) * | 2010-01-07 | 2011-07-14 | Alkermes, Inc. | Prodrugs for the treatment of schizophrenia and bipolar disease |
| US8598156B2 (en) | 2010-03-25 | 2013-12-03 | Glaxosmithkline Llc | Chemical compounds |
| NZ604423A (en) | 2010-06-24 | 2015-01-30 | Alkermes Pharma Ireland Ltd | Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives |
| US8759537B2 (en) | 2010-08-20 | 2014-06-24 | Boehringer Ingelheim International Gmbh | 3H-imidazo [4, 5-C] pyridine-6-carboxamides as anti-inflammatory agents |
| US8586604B2 (en) | 2010-08-20 | 2013-11-19 | Boehringer Ingelheim International Gmbh | Inhibitors of the microsomal prostaglandin E2 synthase-1 |
| UY33779A (es) | 2010-12-10 | 2012-07-31 | Boehringer Ingelheim Int | ?2-(fenilamino)-1H-bencimidazol-5-carboxamidas novedosas? |
| US8466186B2 (en) | 2010-12-10 | 2013-06-18 | Boehringer Ingelheim International Gmbh | Compounds |
| US8486968B2 (en) | 2010-12-10 | 2013-07-16 | Boehringer Ingelheim International Gmbh | Compounds |
| US8894846B2 (en) * | 2010-12-23 | 2014-11-25 | Stephen Lee Yarbro | Using supercritical fluids to refine hydrocarbons |
| ES2972387T3 (es) | 2011-03-18 | 2024-06-12 | Alkermes Pharma Ireland Ltd | Composiciones farmacéuticas que comprenden ésteres de sorbitán |
| GB201106817D0 (en) | 2011-04-21 | 2011-06-01 | Astex Therapeutics Ltd | New compound |
| WO2013088255A1 (en) | 2011-12-15 | 2013-06-20 | Alkermes Pharma Ireland Limited | Prodrugs of secondary amine compounds |
| US9999670B2 (en) | 2012-03-19 | 2018-06-19 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising benzyl alcohol |
| WO2013142202A1 (en) | 2012-03-19 | 2013-09-26 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising glycerol esters |
| CA2867121C (en) | 2012-03-19 | 2021-05-25 | Alkermes Pharma Ireland Limited | Pharmaceutical compositions comprising fatty acid esters |
| JP6654042B2 (ja) | 2012-09-19 | 2020-02-26 | アルカームス ファーマ アイルランド リミテッド | 貯蔵安定性が改善された医薬組成物 |
| US9980973B2 (en) | 2012-10-19 | 2018-05-29 | Astex Therapeutics Limited | Bicyclic heterocycle compounds and their uses in therapy |
| GB201218864D0 (en) | 2012-10-19 | 2012-12-05 | Astex Therapeutics Ltd | Bicyclic heterocycle compounds and their uses in therapy |
| GB201218862D0 (en) | 2012-10-19 | 2012-12-05 | Astex Therapeutics Ltd | Bicyclic heterocycle compounds and their uses in therapy |
| GB201218850D0 (en) | 2012-10-19 | 2012-12-05 | Astex Therapeutics Ltd | Bicyclic heterocycle compounds and their uses in therapy |
| CN115368356B (zh) | 2013-12-20 | 2025-05-09 | 阿斯特克斯治疗有限公司 | 双环杂环化合物及其治疗用途 |
| AU2015231278B2 (en) | 2014-03-20 | 2020-01-23 | Alkermes Pharma Ireland Limited | Aripiprazole formulations having increased injection speeds |
| AU2019230014B2 (en) | 2018-03-05 | 2024-11-28 | Alkermes Pharma Ireland Limited | Aripiprazole dosing strategy |
| WO2020092394A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
| ES2987796T3 (es) | 2018-10-30 | 2024-11-18 | Gilead Sciences Inc | Derivados de N-benzoil-fenilalanina como inhibidores de la integrina alfa4beta7 para el tratamiento de enfermedades inflamatorias |
| WO2020092401A1 (en) | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | COMPOUNDS FOR INHIBITION OF ALPHA 4β7 INTEGRIN |
| DK3873884T3 (da) | 2018-10-30 | 2025-02-17 | Gilead Sciences Inc | 3-(quinolin-8-yl)-1,4-dihydropyrido[3,4-d]pyrimidin-2,4-dion-derivater som alpha4beta7-integrinhæmmere til behandling af inflammatoriske sygdomme |
| AU2020329207B2 (en) | 2019-08-14 | 2024-02-29 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1497118A1 (de) * | 1965-05-29 | 1969-04-17 | Agfa Gevaert Ag | Sensibilisierte elektrophotographische Schichten |
| ZA814057B (en) * | 1980-06-18 | 1982-07-28 | May & Baker Ltd | Indole and indoline derivatives |
| DE68920147T2 (de) * | 1989-10-12 | 1995-06-29 | Ibm | Anzeigesystem. |
| AU693143B2 (en) * | 1993-12-06 | 1998-06-25 | Cytel Corporation | CS-1 peptidomimetics, compositions and methods of using the same |
| WO1998007716A2 (en) | 1996-08-23 | 1998-02-26 | The Board Of Regents For Oklahoma State University | Heteroarotinoids-anticancer agents with receptor specificity and tgase activity |
| DE19647381A1 (de) * | 1996-11-15 | 1998-05-20 | Hoechst Ag | Neue Heterocyclen als Inhibitoren der Leukozytenadhäsion und VLA-4-Antagonisten |
-
1999
- 1999-08-26 PT PT99943058T patent/PT1114028E/pt unknown
- 1999-08-26 BR BR9913222-2A patent/BR9913222A/pt not_active Application Discontinuation
- 1999-08-26 KR KR1020017002476A patent/KR20010085630A/ko not_active Ceased
- 1999-08-26 AT AT99943058T patent/ATE346841T1/de not_active IP Right Cessation
- 1999-08-26 CN CN99811991A patent/CN1323295A/zh active Pending
- 1999-08-26 MX MXPA01001995A patent/MXPA01001995A/es not_active IP Right Cessation
- 1999-08-26 DE DE69934238T patent/DE69934238T2/de not_active Expired - Lifetime
- 1999-08-26 NZ NZ509781A patent/NZ509781A/en unknown
- 1999-08-26 DK DK99943058T patent/DK1114028T3/da active
- 1999-08-26 EP EP99943058A patent/EP1114028B1/de not_active Expired - Lifetime
- 1999-08-26 ES ES99943058T patent/ES2276530T3/es not_active Expired - Lifetime
- 1999-08-26 PL PL99346248A patent/PL346248A1/xx not_active Application Discontinuation
- 1999-08-26 IL IL14159699A patent/IL141596A0/xx active IP Right Grant
- 1999-08-26 HU HU0104766A patent/HUP0104766A3/hu unknown
- 1999-08-26 SK SK261-2001A patent/SK2612001A3/sk unknown
- 1999-08-26 WO PCT/GB1999/002819 patent/WO2000015612A1/en not_active Ceased
- 1999-08-26 CA CA002341677A patent/CA2341677A1/en not_active Abandoned
- 1999-08-26 AU AU56343/99A patent/AU754557B2/en not_active Ceased
- 1999-08-26 US US09/856,106 patent/US6608084B1/en not_active Expired - Lifetime
- 1999-08-26 TR TR2001/00588T patent/TR200100588T2/xx unknown
-
2001
- 2001-02-22 IL IL141596A patent/IL141596A/en not_active IP Right Cessation
- 2001-02-23 NO NO20010942A patent/NO20010942L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1114028B1 (de) | 2006-11-29 |
| NZ509781A (en) | 2003-05-30 |
| WO2000015612A1 (en) | 2000-03-23 |
| DE69934238T2 (de) | 2007-06-21 |
| AU5634399A (en) | 2000-04-03 |
| IL141596A0 (en) | 2002-03-10 |
| PL346248A1 (en) | 2002-01-28 |
| CA2341677A1 (en) | 2000-03-23 |
| DK1114028T3 (da) | 2007-04-30 |
| MXPA01001995A (es) | 2004-07-30 |
| NO20010942D0 (no) | 2001-02-23 |
| DE69934238D1 (de) | 2007-01-11 |
| BR9913222A (pt) | 2001-10-16 |
| KR20010085630A (ko) | 2001-09-07 |
| PT1114028E (pt) | 2007-02-28 |
| TR200100588T2 (tr) | 2001-08-21 |
| ES2276530T3 (es) | 2007-06-16 |
| HUP0104766A3 (en) | 2002-08-28 |
| SK2612001A3 (en) | 2001-11-06 |
| EP1114028A1 (de) | 2001-07-11 |
| AU754557B2 (en) | 2002-11-21 |
| US6608084B1 (en) | 2003-08-19 |
| NO20010942L (no) | 2001-04-19 |
| HUP0104766A2 (hu) | 2002-04-29 |
| IL141596A (en) | 2006-07-05 |
| CN1323295A (zh) | 2001-11-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69934238D1 (de) | Azabicyclo-verbindungen welche die inhibition der zell adhesion modulieren | |
| WO2002025376A3 (en) | Oxime derivatives and the use thereof as latent acids | |
| DE69521500D1 (de) | Phosphorsäurediester-derivate | |
| HUP9802859A2 (hu) | Acil-amino-szalicilsav-amid-származékok és alkalmazásuk peszticidként | |
| SU496737A3 (ru) | Способ получени серусодержащих кремнийорганических соединений | |
| DK174772B1 (da) | Fremgangsmåde til fremstilling af nucleotider og hertil anvendelige forbindelser | |
| DE60009480D1 (de) | Harnstoffderivate und ihr gebrauch als zell adhesion modulatoren | |
| ATE108470T1 (de) | Polymerisationsverfahren unter verwendung von verbindungen mit polymerisierbaren acylurethan- strukturen. | |
| DK1706414T3 (da) | Fremgangsmåde til fluorcytidinderivater | |
| AP2000001924A0 (en) | Dihydro-benzo(1,4)oxazines and tetrahydroquinoxalines. | |
| FI971227A0 (fi) | Pyramidinyylipyratsolijohdannaisia | |
| NO20020029D0 (no) | Fremgangsmåte for fremstilling av amilodipinbenzensulfonat | |
| DE60309251D1 (de) | Verfahren zur Herstellung von Donepezil | |
| EP1602649A3 (de) | Verfahren zur Herstellung von monofunktionalisiertem 1,4,7,10-Tetraazacyclododecan | |
| TR200002950T2 (tr) | Matris-Metaloproteinaz önleyicilerinin üretiminde faydalı alkilleştirici engellenmiş sülfonamitlerin işlemi. | |
| DE60140333D1 (de) | Lichtempfindliche Verbindung und lichtempfindliches Harz | |
| CA2274375A1 (en) | Process for preparing 3-arylsulfur hydroxamic acids | |
| CA1205809A (en) | Process for the preparation of 2-(thien-2-yl)- and 2- (thien-3-yl)-ethylamine derivatives | |
| DK2887D0 (da) | Phosphonyl-hydroxyacyl-proliner | |
| DE69910140D1 (de) | Verfahren zur Sulfurierung von Phosphor-enthaltenden Verbindungen | |
| ES480969A1 (es) | Procedimiento para la aclaracion optica de materiales organicos, en especial de tipo textil. | |
| EA200001077A3 (ru) | Новые соединения аминопирролина, способ их получения и содержащие их фармацевтические композиции | |
| ATE194388T1 (de) | Stereoselektive herstellung von 2-substituierten succinatderivaten | |
| TW363967B (en) | Bisquaternary ammonium compound of 2,2'- dimethyl-l, l'-binaphthyl and process for their preparation | |
| EA200000876A1 (ru) | Дигидробензо(1,4)оксазины и тетрагидрохиноксалины |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1114028 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |