ATE374018T1 - Prozess zur herstellung von nano- und mikrokapseln aus spinnenseidenprotein - Google Patents

Prozess zur herstellung von nano- und mikrokapseln aus spinnenseidenprotein

Info

Publication number
ATE374018T1
ATE374018T1 AT05016712T AT05016712T ATE374018T1 AT E374018 T1 ATE374018 T1 AT E374018T1 AT 05016712 T AT05016712 T AT 05016712T AT 05016712 T AT05016712 T AT 05016712T AT E374018 T1 ATE374018 T1 AT E374018T1
Authority
AT
Austria
Prior art keywords
spider silk
silk protein
producing nano
micro capsules
nano
Prior art date
Application number
AT05016712T
Other languages
English (en)
Inventor
Thomas Scheibel
Andreas Bausch
Daniel Huemmerich
Kevin Hermanson
Original Assignee
Univ Muenchen Tech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Muenchen Tech filed Critical Univ Muenchen Tech
Application granted granted Critical
Publication of ATE374018T1 publication Critical patent/ATE374018T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/11—Encapsulated compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5052—Proteins, e.g. albumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5169—Proteins, e.g. albumin, gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5192—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
    • C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/413—Nanosized, i.e. having sizes below 100 nm

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Birds (AREA)
  • Optics & Photonics (AREA)
  • Nanotechnology (AREA)
  • Biomedical Technology (AREA)
  • Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Insects & Arthropods (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
AT05016712T 2005-08-01 2005-08-01 Prozess zur herstellung von nano- und mikrokapseln aus spinnenseidenprotein ATE374018T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05016712A EP1757276B1 (de) 2005-08-01 2005-08-01 Prozess zur Herstellung von Nano- und Mikrokapseln aus Spinnenseidenprotein

Publications (1)

Publication Number Publication Date
ATE374018T1 true ATE374018T1 (de) 2007-10-15

Family

ID=35197006

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05016712T ATE374018T1 (de) 2005-08-01 2005-08-01 Prozess zur herstellung von nano- und mikrokapseln aus spinnenseidenprotein

Country Status (12)

Country Link
US (2) US8372436B2 (de)
EP (1) EP1757276B1 (de)
JP (1) JP5129746B2 (de)
CN (1) CN101309676B (de)
AT (1) ATE374018T1 (de)
CA (1) CA2617530C (de)
DE (1) DE602005002654T2 (de)
DK (1) DK1757276T3 (de)
ES (1) ES2294606T3 (de)
PL (1) PL1757276T3 (de)
PT (1) PT1757276E (de)
WO (1) WO2007014755A1 (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6092337A (ja) * 1983-10-26 1985-05-23 Sekisui Plastics Co Ltd 発泡フエノ−ル樹脂成形物の製造方法
CN101370556A (zh) * 2006-01-20 2009-02-18 巴斯夫欧洲公司 蛋白质微粒在化妆品中的用途
EP2097117B1 (de) * 2006-12-11 2013-05-22 Medizinische Hochschule Hannover Implantat aus vernetzten spinnen-seidenfäden
JP2008201767A (ja) * 2007-01-24 2008-09-04 Fujifilm Corp 頭髪用組成物
US20080175807A1 (en) 2007-01-24 2008-07-24 Fujifilm Corporation Composition for hair
JP2008255020A (ja) * 2007-04-02 2008-10-23 Fujifilm Corp 抗老化皮膚外用剤
CA2683974A1 (en) * 2007-04-18 2008-10-30 The Regents Of The University Of California Protein-modified nano-droplets, compositions and methods of production
WO2008155304A1 (de) * 2007-06-20 2008-12-24 Basf Se Synthetische repetitive proteine, deren herstellung und verwendung
JP5889199B2 (ja) * 2009-11-30 2016-03-22 アーエムシルク ゲーエムベーハー 化合物の制御送達及び持続送達のためのシルク粒子
EP2549986B1 (de) * 2010-03-24 2019-10-30 Northeastern University Makrophagenabgabe an mehrere ziele
KR101494711B1 (ko) 2011-11-04 2015-02-26 동아대학교 산학협력단 산왕거미 유래 메이저 엠풀레이트 스피드로인 단백질의 반복적인 ｃ-말단 영역의 폴리펩티드 서열 및 이를 코딩하는 염기서열
CN104822366B (zh) * 2012-07-13 2018-03-06 塔夫茨大学 在丝纤蛋白生物材料中香料和/或调味剂的包封
BR112015000739A2 (pt) * 2012-07-13 2017-06-27 Univ Tufts encapsulamento de fases imiscíveis em biomaterials fibroina de seda
JP6450680B2 (ja) * 2012-09-06 2019-01-09 アーエムシルク ゲーエムベーハー 高靱性シルク繊維を作製する方法
WO2014152097A1 (en) * 2013-03-15 2014-09-25 Banner Pharmacaps Inc. Silk-based capsules
GB201415681D0 (en) * 2014-09-04 2014-10-22 Cambridge Entpr Ltd And President And Fellows Of Harvard College Protien Capsules
DE102014218503A1 (de) 2014-09-16 2016-03-17 Henkel Ag & Co. Kgaa Proteinhaltiges Waschmittel
DE102014218502A1 (de) 2014-09-16 2016-03-17 Henkel Ag & Co. Kgaa Proteinhaltiges Reinigungsmittel
DE102014218507A1 (de) 2014-09-16 2016-03-17 Henkel Ag & Co. Kgaa Spinnenseidenproteine als Enzymstabilisatoren
PE20171791A1 (es) 2014-12-02 2017-12-28 Silk Therapeutics Inc Prendas de vestir de seda y productos de alto rendimiento y metodos para elaborarla
CN104927777B (zh) * 2015-06-02 2018-04-24 清华大学深圳研究生院 相变储能微胶囊制备方法及应用
HK1255640A1 (zh) 2015-07-14 2019-08-23 Evolved By Nature, Inc. 丝性能服装和产品及其制备方法
ES3024660T3 (en) 2016-06-22 2025-06-05 Amsilk Gmbh Articles comprising a silk polypeptide for antigen delivery
DE102016222480B4 (de) 2016-11-16 2020-02-13 Adidas Ag Bekleidungsstück, das Spinnenseide aufweist oder Schuh, der Spinnenseide aufweist, und ein entsprechendes Herstellungsverfahren
US11390988B2 (en) 2017-09-27 2022-07-19 Evolved By Nature, Inc. Silk coated fabrics and products and methods of preparing the same
CA3109325A1 (en) 2018-08-17 2020-02-20 Amsilk Gmbh Use of a structural polypeptide for plant coating
CN109329910A (zh) * 2018-09-28 2019-02-15 青岛大学 一种蜘蛛丝组合物口服液的制备方法
CA3144971A1 (en) * 2019-07-12 2021-01-21 Bolt Threads, Inc. Recombinant spider silk extrudate formulations
US12403216B2 (en) * 2019-10-18 2025-09-02 Trustees Of Tufts College Chemical modification of silk fibroin for fabrication of enzymatically crosslinked hydrogels with tunable gelation kinetics and bioactivity
CN111214385B (zh) * 2020-03-13 2022-05-17 珀莱雅化妆品股份有限公司 一种负载皮肤营养剂的纳米粒乳液及其制备方法
US20240050353A1 (en) * 2020-12-24 2024-02-15 University Of Tsukuba Fibroin micro-sphere and method for producing same
WO2023076924A1 (en) 2021-10-26 2023-05-04 Rensselaer Polytechnic Institute Systems and methods for increased production of recombinant biopolymers via genome engineering and downregulation of basal expression
WO2023152202A1 (en) 2022-02-10 2023-08-17 Amsilk Gmbh Gradient printing reservoir and printing method

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2683159B1 (fr) * 1991-10-31 1994-02-25 Coletica Procede de fabrication de nanocapsules a paroi a base de proteines reticulees; nanocapsules ainsi obtenues et compositions cosmetiques, pharmaceutiques et alimentaires en comportant application.
JP3094181B2 (ja) * 1992-04-09 2000-10-03 清 山内 再生天然ケラチンを壁材とするマイクロカプセル及びその製造方法
ATE253635T1 (de) 1993-06-15 2003-11-15 Du Pont Rekombinante spinnerseide analoge
JPH08268905A (ja) 1995-03-31 1996-10-15 Takayuki Nagashima コロイド状絹フィブロイン及びそれを含有する組成物
JPH08295697A (ja) 1995-04-26 1996-11-12 Kanebo Ltd 高濃度絹フィブロイン水溶液の製造方法
JP2997758B2 (ja) 1996-01-23 2000-01-11 農林水産省蚕糸・昆虫農業技術研究所長 創傷被覆材
JP3537297B2 (ja) 1996-08-15 2004-06-14 聖治 寺内 フィブロイン流動体及びその製造方法
FR2774588B1 (fr) * 1998-02-11 2000-05-05 Oreal Composition cosmetique ou dermatologique contenant au moins une proteine de soie d'arachnides naturelle, recombinante ou un analogue
JP2972877B1 (ja) * 1998-07-24 1999-11-08 農林水産省蚕糸・昆虫農業技術研究所長 高分子素材のドープ、高分子素材からなるマイクロビーズおよびそのビーズの製造方法
JP2001163899A (ja) 1999-12-09 2001-06-19 Natl Inst Of Sericultural & Entomological Science 機能性絹フィブロインの製造方法とその利用
US6608242B1 (en) 2000-05-25 2003-08-19 E. I. Du Pont De Nemours And Company Production of silk-like proteins in plants
WO2003045336A1 (en) * 2001-11-29 2003-06-05 National Institute Of Agrobiological Sciences Emulsifier and process for producing the same
US20040132978A1 (en) * 2002-11-12 2004-07-08 Fahnestock Stephen R. Method for purifying and recovering silk proteins in soluble form and uses thereof
CN1288193C (zh) * 2004-03-10 2006-12-06 复旦大学 蚕丝蛋白纳米微球及其制备方法
CA2608862C (en) 2004-06-11 2020-05-05 Trustees Of Tufts College Silk-based drug delivery system

Also Published As

Publication number Publication date
DE602005002654T2 (de) 2008-06-19
EP1757276A1 (de) 2007-02-28
US8729238B2 (en) 2014-05-20
WO2007014755A1 (en) 2007-02-08
EP1757276B1 (de) 2007-09-26
CA2617530A1 (en) 2007-02-08
DK1757276T3 (da) 2008-02-04
CA2617530C (en) 2013-10-01
US8372436B2 (en) 2013-02-12
ES2294606T3 (es) 2008-04-01
CN101309676A (zh) 2008-11-19
US20130136779A1 (en) 2013-05-30
PT1757276E (pt) 2008-01-02
US20100056438A1 (en) 2010-03-04
JP5129746B2 (ja) 2013-01-30
PL1757276T3 (pl) 2008-02-29
DE602005002654D1 (de) 2007-11-08
CN101309676B (zh) 2012-02-29
JP2009502492A (ja) 2009-01-29

Similar Documents

Publication Publication Date Title
DE602005002654D1 (de) Prozess zur Herstellung von Nano- und Mikrokapseln aus Spinnenseidenprotein
SE0301010D0 (sv) Novel compounds
ATE520656T1 (de) Verfahren zur herstellung von 2-oxo-1- pyrrolidinderivaten
DE602006012459D1 (de) Screening-verfahren, verfahren zur aufreinigung nichtdiffundierbarer a-beta-oligomere, selektive antikörper gegen diese nichtdiffundierbaren a-beta-oligomere und verfahren zur herstellung dieser antikörper
ATE444746T1 (de) Eine herstellungsmethode von entacapon- enthaltenden granulaten für orale dosierformen
EA200901529A1 (ru) Производные арилоазол-2-илцианоэтиламина, способ их получения и способ их применения
NO20070687L (no) Ny karbamylert EPO og fremgangsmate for deres fremstilling
DE602004014121D1 (de) Luftdüsenverfahren zur herstellung von elastischen verbundgarnen
EP1726299A3 (de) Kerne und Mikrokapsel zur parenteralen Verabreichung sowie Verfahren zu deren Herstellung
ATE473224T1 (de) Verfahren zur herstellung von nebivolol
ATE548353T1 (de) Verfahren zur herstellung von substituierte n- aryl-n'-ä3-(1h-pyrazol-5-yl)phenylü-harnstoffe and intermediate davon.
WO2002099082A3 (en) Expression of spider silk proteins in higher plants
WO2007052023A3 (en) Novel compounds
WO2007025861A3 (de) Modifizierte kohlenstoff-nanopartikel, verfahren zu deren herstellung und deren verwendung
DK1668001T3 (da) Substituerede heteroarylbenzofuransyrer
ATE486857T1 (de) Verfahren zur herstellung von telmisartan
DE502006001472D1 (de) Verfahren zur kontinuierlichen Herstellung von hochviskosen vernetzbaren Siliconmassen
IN2015DN02596A (de)
ATE442355T1 (de) Herstellung von 4,5-dialkyl-3-acylpyrrol-2- carbonsäurederivaten durch synthese nach fischer- fink und anschliebende acylierung
DE502005003727D1 (de) Verfahren zur Herstellung von nanopartikulären Feststoffen
EA200900257A1 (ru) Полиморфные формы сульфатов зипразидона
DE602004001646D1 (de) Verfahren zur Herstellung von Pyran
DE60322416D1 (de) Methode zur herstellung von indan-1,3-dicarbonsäuren
ATE464289T1 (de) Neues verfahren zur herstellung von thoc
ATE498601T1 (de) Neues verfahren zur herstellung von timberon

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1757276

Country of ref document: EP