ATE396400T1 - Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand - Google Patents

Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand

Info

Publication number
ATE396400T1
ATE396400T1 AT07008841T AT07008841T ATE396400T1 AT E396400 T1 ATE396400 T1 AT E396400T1 AT 07008841 T AT07008841 T AT 07008841T AT 07008841 T AT07008841 T AT 07008841T AT E396400 T1 ATE396400 T1 AT E396400T1
Authority
AT
Austria
Prior art keywords
protein
known ligand
receptor coupled
rup3 receptor
human rup3
Prior art date
Application number
AT07008841T
Other languages
English (en)
Inventor
Ruoping Chen
James N Leonard
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Application granted granted Critical
Publication of ATE396400T1 publication Critical patent/ATE396400T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Plant Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT07008841T 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand ATE396400T1 (de)

Applications Claiming Priority (23)

Application Number Priority Date Filing Date Title
US10921398P 1998-11-20 1998-11-20
US12041699P 1999-02-16 1999-02-16
US12185299P 1999-02-26 1999-02-26
US12394699P 1999-03-12 1999-03-12
US12394999P 1999-03-12 1999-03-12
US13713199P 1999-05-28 1999-05-28
US13712799P 1999-05-28 1999-05-28
US13643799P 1999-05-28 1999-05-28
US13643999P 1999-05-28 1999-05-28
US13643699P 1999-05-28 1999-05-28
US13656799P 1999-05-28 1999-05-28
US14144899P 1999-06-29 1999-06-29
US15663499P 1999-09-29 1999-09-29
US15663399P 1999-09-29 1999-09-29
US15665399P 1999-09-29 1999-09-29
US15655599P 1999-09-29 1999-09-29
US15728199P 1999-10-01 1999-10-01
US15728299P 1999-10-01 1999-10-01
US15728099P 1999-10-01 1999-10-01
US15729399P 1999-10-01 1999-10-01
US15729499P 1999-10-01 1999-10-01
US41676099A 1999-10-12 1999-10-12
US41704499A 1999-10-12 1999-10-12

Publications (1)

Publication Number Publication Date
ATE396400T1 true ATE396400T1 (de) 2008-06-15

Family

ID=27586698

Family Applications (3)

Application Number Title Priority Date Filing Date
AT99972682T ATE301673T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand
AT07008841T ATE396400T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelte rezeptor rup3 ohne bekannte ligand
AT05003040T ATE366815T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT99972682T ATE301673T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT05003040T ATE366815T1 (de) 1998-11-20 1999-10-13 Menschliche, an ein g-protein gekoppelter rezeptor rup3 ohne bekannten ligand

Country Status (12)

Country Link
EP (8) EP1580271A3 (de)
JP (5) JP2003534767A (de)
KR (5) KR100926208B1 (de)
AT (3) ATE301673T1 (de)
AU (2) AU770056B2 (de)
CA (2) CA2645717A1 (de)
DK (3) DK1133559T3 (de)
ES (3) ES2289610T3 (de)
IL (2) IL142538A0 (de)
NZ (3) NZ527622A (de)
PT (3) PT1133559E (de)
WO (1) WO2000031258A2 (de)

Families Citing this family (92)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1690939B8 (de) 1998-03-12 2010-10-13 Astellas Pharma Inc. Neue G Protein-gekoppelte Rezeptorproteine
US6071722A (en) * 1998-04-24 2000-06-06 Smithkline Beecham Corporation Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)
JP2002512780A (ja) * 1998-04-24 2002-05-08 スミスクライン ビーチャム コーポレーション 新規７ｔｍ受容体ａｘｏｒ−２のクローニング
WO2000026339A2 (en) * 1998-11-03 2000-05-11 Smithkline Beecham Corporation Axor14, a g-protein coupled receptor
USRE42190E1 (en) 1998-11-20 2011-03-01 Arena Pharmaceuticals, Inc. Method of identifying a compound for inhibiting or stimulating human G protein-coupled receptors
US20030017528A1 (en) 1998-11-20 2003-01-23 Ruoping Chen Human orphan G protein-coupled receptors
US7816492B2 (en) 1998-11-20 2010-10-19 Arena Pharmaceuticals, Inc. Human G protein-coupled receptors
US6221660B1 (en) 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
EP1157038A4 (de) * 1999-02-26 2005-01-19 Smithkline Beecham Corp KLONIERUNG EINES P2Y-äHNLICHEN 7TM-REZEPTORS (AXOR17)
US6620615B1 (en) * 1999-04-23 2003-09-16 Curagen Corporation G-protein coupled receptor—encoding nucleic acids
EP1189944A4 (de) * 1999-06-21 2002-09-11 Smithkline Beecham Corp G-protein gekoppelter rezeptor axor16
JP2003504054A (ja) * 1999-07-13 2003-02-04 メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフトング Ｇ−タンパク質共役型受容体およびそのｄｎａ配列
CA2381437A1 (en) * 1999-07-30 2001-02-08 Merck Patent Gesellschaft Mit Beschraenkter Haftung G-protein coupled receptor and dna sequences thereof
CA2382889A1 (en) * 1999-08-27 2001-03-08 Takuya Watanabe Novel g protein-coupled receptor protein and dna thereof
US6998255B1 (en) 1999-09-24 2006-02-14 Solvay Pharmaceuticals B.V. Human G-protein coupled receptor
GB9923177D0 (en) * 1999-09-30 1999-12-01 Pfizer Ltd Novel polypeptide
US6204017B1 (en) 1999-10-07 2001-03-20 Schering Corporation Polynucleotide encoding a histamine receptor
GB9923890D0 (en) * 1999-10-08 1999-12-08 Pfizer Ltd Novel polypeptide
GB9923893D0 (en) * 1999-10-08 1999-12-08 Pfizer Ltd Novel polypeptide
GB9924960D0 (en) * 1999-10-21 1999-12-22 Pfizer Ltd Novel polypeptide
GB9924956D0 (en) * 1999-10-21 1999-12-22 Pfizer Ltd Novel polypeptide
AU1575601A (en) * 1999-10-27 2001-05-08 Pharmacia & Upjohn Company G protein-coupled receptors expressed in brain
ATE375390T1 (de) * 1999-10-29 2007-10-15 Pfizer G-protein-gekoppelter rezeptor-ähnliche proteine
WO2001032864A2 (en) * 1999-11-03 2001-05-10 Merck Patent Gmbh Gpcr-kd5 polypeptides and dna sequences thereof
US6461836B1 (en) * 1999-11-05 2002-10-08 Smithkline Beecham Corporation Molecular cloning of a 7TM receptor (AxOR34) and screening methods thereof
AU784543B2 (en) * 1999-11-16 2006-04-27 Pharmacia & Upjohn Company Novel G protein-coupled receptors
US7029857B1 (en) 1999-12-17 2006-04-18 H. Lundbeck A/S Processes for obtaining compounds employing SNORF72 receptors
WO2001046414A1 (fr) * 1999-12-20 2001-06-28 Banyu Pharmaceutical Co., Ltd. Nouvelle proteine receptrice couplee a la proteine de fixation de guanosine triphosphate, bg26
AU2288601A (en) 1999-12-23 2001-07-03 Millennium Pharmaceuticals, Inc. P2Y12 receptor
AU2230401A (en) * 1999-12-28 2001-07-09 Helix Research Institute Novel guanosine triphosphate-binding protein-coupled receptors, genes thereof and production and use of the same
GB0001700D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Novel protein
DE60129933T2 (de) 2000-02-04 2008-02-14 Takeda Pharmaceutical Co. Ltd. Verfahren zum screening
EP1266005B1 (de) * 2000-03-14 2007-03-07 Bayer HealthCare AG Regulation des menschliches lipoxin a4 rezeptor-ähnliches protein
WO2001068844A2 (en) * 2000-03-17 2001-09-20 Bayer Aktiengesellschaft Regulation of human leukotriene b4-like g protein-coupled receptor
US20030077709A1 (en) * 2000-03-21 2003-04-24 Masazumi Kamohara Novel leukotriene B4 receptor
AU2001242800A1 (en) * 2000-03-28 2001-10-08 Takeda Chemical Industries Ltd. Novel g protein-coupled receptor protein and dna thereof
WO2001073023A1 (fr) * 2000-03-31 2001-10-04 Helix Research Institute Nouveau recepteur gprv53 couple a une proteine se liant a la guanosine-triphosphate, gene correspondant et procede de production et d'utilisation associe
WO2001077326A1 (fr) * 2000-04-12 2001-10-18 Takeda Chemical Industries, Ltd. Proteine receptrice couplee a la proteine g et son adn
EP1178110A1 (de) * 2000-08-01 2002-02-06 Aventis Pharma Deutschland GmbH EDG8 Rezeptor für Sphingosine 1-Phosphate , dessen Herstellung und Anwendung
EP1287133B1 (de) * 2000-05-18 2006-12-13 Bayer HealthCare AG Regulation eines menschlichen dopamine-ähnlichen g-protein gekoppelten rezeptor.
WO2002000719A2 (en) * 2000-06-23 2002-01-03 Tularik Inc. Human and mouse g-protein couipled receptors
WO2002000725A2 (en) * 2000-06-26 2002-01-03 Akzo Nobel N.V. G-protein coupled receptor org10
WO2002002599A2 (en) * 2000-06-30 2002-01-10 Ingenium Pharmaceuticals Ag HUMAN G PROTEIN-COUPLED RECEPTOR IGPcR17, AND USES THEROF
AU2001271838A1 (en) 2000-07-06 2002-01-21 Bayer Corporation Human neuropeptide y-like g protein-coupled receptor
EP1311546A2 (de) * 2000-08-09 2003-05-21 Millenium Pharmaceuticals, Inc. Verfahren zur verwendung des menschlichen g-protein-gekoppelten rezeptors 14266
US6790608B2 (en) 2000-09-20 2004-09-14 The Regents Of The University Of California Methods of identifying and ADP-glucose receptor ligand, agonist or antagonist
AU2002210982A1 (en) 2000-11-01 2002-05-15 Yamanouchi Pharmaceutical Co..Ltd. Method of screening antiplatelet
JP4178028B2 (ja) * 2000-11-07 2008-11-12 タケダ ケンブリッジ リミテッド 受容体
AU1989002A (en) * 2000-11-27 2002-06-03 Arena Pharm Inc Endogenous and non-endogenous versions of human g protein-coupled receptors
EP1338651B9 (de) 2000-12-01 2007-05-09 Astellas Pharma Inc. Verfahren zum screening von diabetes-heilverfahren
AU2002246680A1 (en) 2000-12-22 2002-07-30 University Of South Florida Sphingosine 1-phosphate receptor gene, sppr
WO2002052047A2 (en) * 2000-12-22 2002-07-04 Mergen Ltd. Methods for identifying g-protein coupled receptors associated with diseases
GB0100782D0 (en) * 2001-01-11 2001-02-21 Glaxo Group Ltd Assay
ES2311601T3 (es) * 2001-04-25 2009-02-16 Astellas Pharma Inc. Receptores acoplado a proteina que se une a trifosfato de guanosina place 6002312 y su gen y produccion y uso del mismo.
US7858755B2 (en) 2001-07-09 2010-12-28 Euroscreen S.A. Monoclonal antibodies that bind Chemerin polypeptide
US7419658B2 (en) 2001-07-09 2008-09-02 Euroscreen S.A. Isolated ligand of ChemerinR
US20030096299A1 (en) 2001-07-09 2003-05-22 Valerie Wittamer Natural ligand of G protein coupled receptor ChemR23 and uses thereof
US6946244B2 (en) 2001-08-07 2005-09-20 Euroscreen, S.A. Methods of identifying a ligand, an agonist, and an antagonist of G protein coupled receptor GPR86 (P2Y13)
CN1324047C (zh) 2002-04-12 2007-07-04 先灵公司 G蛋白偶联受体的配体与方法
AU2003261874A1 (en) * 2002-09-02 2004-03-29 Takeda Pharmaceutical Company Limited Adrenocortical hormone secretion controller
JPWO2004033687A1 (ja) * 2002-10-11 2006-02-09 アステラス製薬株式会社 腎不全治療薬をスクリーニングする方法
US7056685B1 (en) 2002-11-05 2006-06-06 Amgen Inc. Receptor ligands and methods of modulating receptors
JP4516430B2 (ja) 2002-12-20 2010-08-04 メルク・シャープ・エンド・ドーム・コーポレイション １−（アミノ）インダン並びに（１，２−ジヒドロ−３−アミノ）−ベンゾフラン、ベンゾチオフェン及びインドール
CA2512899A1 (en) 2003-01-14 2004-08-05 Arena Pharmaceuticals Inc. 1,2,3-trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto such as diabetes and hyperglycemia
US7083933B1 (en) 2003-05-09 2006-08-01 Prosidion Limited Methods for identification of modulators of OSGPR116 activity
US7524638B1 (en) 2003-06-27 2009-04-28 Osi Pharmaceuticals, Inc. Methods for identification of modulators of OSGPR114 or OSGPR78 activity, and their use in the treatment of disease
CN1812803A (zh) * 2003-06-27 2006-08-02 唐纳士公司 人类肥大细胞表达的膜蛋白
DOP2006000008A (es) * 2005-01-10 2006-08-31 Arena Pharm Inc Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
GB0508990D0 (en) * 2005-05-03 2005-06-08 Novartis Ag Organic compounds
EP1971862B1 (de) 2006-04-11 2010-11-10 Arena Pharmaceuticals, Inc. Verfahren zur verwendung des gpr119-rezeptors zur identifizierung von verbindungen zur erhöhung der knochenmasse bei einer person
US7638541B2 (en) 2006-12-28 2009-12-29 Metabolex Inc. 5-ethyl-2-{4-[4-(4-tetrazol-1-yl-phenoxymethyl)-thiazol-2-yl]-piperidin-1-yl}-pyrimidine
BRPI0814294A2 (pt) 2007-07-19 2015-02-03 Metabolex Inc Agonistas de receptor heterocíclico ligado a n para o tratamento do diabetes e de desordens metabólicas.
JP5465177B2 (ja) 2007-09-20 2014-04-09 アイアールエム・リミテッド・ライアビリティ・カンパニー Ｇｐｒ１１９活性のモジュレーターとしての化合物および組成物
EP2108960A1 (de) 2008-04-07 2009-10-14 Arena Pharmaceuticals, Inc. Verfahren zur Verwendung eines A G Protein-gekoppelten Rezeptors zur Identifikation von Peptid YY (PYY) Sekretagoga und nützliche Verbindungen zur Behandlung von durch (PYY) Sekretagoga modulierten Zuständen und nützliche Verbindungen zur Behandlung von Zuständen durch PYY
AR077642A1 (es) 2009-07-09 2011-09-14 Arena Pharm Inc Moduladores del metabolismo y el tratamiento de trastornos relacionados con el mismo
US8410127B2 (en) 2009-10-01 2013-04-02 Metabolex, Inc. Substituted tetrazol-1-yl-phenoxymethyl-thiazol-2-yl-piperidinyl-pyrimidine salts
US8791100B2 (en) 2010-02-02 2014-07-29 Novartis Ag Aryl benzylamine compounds
JP2013523819A (ja) 2010-04-06 2013-06-17 アリーナ ファーマシューティカルズ， インコーポレイテッド Ｇｐｒ１１９レセプターのモジュレーターおよびそれに関連する障害の処置
BR112012032248A2 (pt) 2010-06-23 2016-09-13 Metabolex Inc composições de 5-etil-2-{4-[-4(-4-tetrazol-1-il-fenoximetil)-tiazol-2-il]-piperidin-1-il}-pirimidina
CN103539791B (zh) 2010-09-22 2017-01-11 艾尼纳制药公司 Gpr119 受体调节剂和对与其相关的障碍的治疗
US20140018371A1 (en) 2011-04-01 2014-01-16 Arena Pharmaceuticals, Inc. Modulators Of The GPR119 Receptor And The Treatment Of Disorders Related Thereto
WO2012145361A1 (en) 2011-04-19 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012145604A1 (en) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012145603A1 (en) 2011-04-22 2012-10-26 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2012170702A1 (en) 2011-06-08 2012-12-13 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2013055910A1 (en) 2011-10-12 2013-04-18 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
WO2014074668A1 (en) 2012-11-08 2014-05-15 Arena Pharmaceuticals, Inc. Modulators of gpr119 and the treatment of disorders related thereto
CA3002540C (en) 2015-01-06 2023-11-07 Arena Pharmaceuticals, Inc. Use of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl)acetic acid for treating conditions related to the s1p1 receptor
WO2016209809A1 (en) 2015-06-22 2016-12-29 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid(compound1) for use in sipi receptor-associated disorders
AU2017305392A1 (en) 2016-08-03 2019-02-21 Cymabay Therapeutics, Inc. Oxymethylene aryl compounds for treating inflammatory gastrointestinal diseases or gastrointestinal conditions
MA49456A (fr) 2017-06-19 2020-04-29 Arena Pharm Inc Composés et procédés pour le traitement de nafld et de nash
ES2987794T3 (es) 2018-06-06 2024-11-18 Arena Pharm Inc Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2237937A1 (en) * 1995-11-15 1997-06-05 Cor Therapeutics, Inc. Novel purinergic receptor
WO1997024929A1 (en) * 1996-01-11 1997-07-17 Human Genome Sciences, Inc. Human g-protein coupled receptor
WO1998031810A2 (en) * 1997-01-21 1998-07-23 Schering Corporation Mammalian chemokines; receptors; reagents; uses
US6221627B1 (en) * 1997-02-24 2001-04-24 Smithkline Beecham Corporation cDNA clone HDPB130 that encodes a novel human 7-transmembrane receptor
US5955303A (en) * 1997-03-06 1999-09-21 Incyte Pharmaceuticals, Inc. Human chemokine receptor-like protein
US6555339B1 (en) * 1997-04-14 2003-04-29 Arena Pharmaceuticals, Inc. Non-endogenous, constitutively activated human protein-coupled receptors
US6060272A (en) * 1997-05-07 2000-05-09 Human Genome Sciences, Inc. Human G-protein coupled receptors
EP0899332A3 (de) * 1997-08-15 2000-07-05 Smithkline Beecham Corporation G-Protein gekoppelter Rezeptor HFIAO41
CA2239255A1 (en) * 1997-10-23 1999-04-23 Smithkline Beecham Corporation Cdna clone hneaa81 that encodes a human 7-transmembrane receptor
US5932445A (en) * 1997-11-07 1999-08-03 Incyte Pharmaceuticals, Inc. Signal peptide-containing proteins
KR100629185B1 (ko) * 1997-11-11 2006-09-28 오노 야꾸힝 고교 가부시키가이샤 인간 리조포스파티드산 수용체 물질 및 그 용도
US6207412B1 (en) * 1997-11-13 2001-03-27 The Regents Of The University Of California Identification of a G protein-coupled receptor transcriptionally regulated by protein tyrosine kinase signaling in hematopoietic cells
EP1054903A4 (de) * 1998-02-20 2002-10-09 Smithkline Beecham Corp Fischboy, ein g-protein gekoppelter rezeptor
EP1690939B8 (de) * 1998-03-12 2010-10-13 Astellas Pharma Inc. Neue G Protein-gekoppelte Rezeptorproteine
AU3749499A (en) * 1998-04-16 1999-11-01 Millenium Pharmaceuticals, Inc. Novel molecules of the bgckr-related protein family and uses thereof
JP2002512780A (ja) * 1998-04-24 2002-05-08 スミスクライン ビーチャム コーポレーション 新規７ｔｍ受容体ａｘｏｒ−２のクローニング
SE9801455D0 (sv) * 1998-04-24 1998-04-24 Astra Pharma Inc New receptor
US6071722A (en) * 1998-04-24 2000-06-06 Smithkline Beecham Corporation Nucleic acids encoding a G-protein coupled 7TM receptor (AXOR-1)
JP2002531057A (ja) * 1998-08-19 2002-09-24 ミレニアム・ファーマシューティカルズ・インコーポレイテッド Ｅｄｇ受容体ファミリーに関連したｇタンパク質結合受容体である１４２７４受容体
EP1104465A1 (de) * 1998-08-20 2001-06-06 Millennium Pharmaceuticals, Inc. 14400 rezeptor, ein g-protein gekoppeltes rezeptor
WO2000011015A1 (en) * 1998-08-24 2000-03-02 Alphagene, Inc. Secreted proteins and polynucleotides encoding them
WO2000012707A1 (en) * 1998-09-02 2000-03-09 Millennium Pharmaceuticals, Inc. 14926 receptor, a novel g-protein coupled receptor
NZ510712A (en) * 1998-10-13 2004-11-26 Arena Pharm Inc Non-endogenous, constitutively activated human G protein-coupled receptors
WO2000023588A2 (en) * 1998-10-16 2000-04-27 Millennium Pharmaceuticals, Inc. G-protein coupled receptors
EP1127128A1 (de) * 1998-11-04 2001-08-29 Chiron Corporation Isolierte vshk-1 rezeptor-polypeptide und verfahren zu deren anwendung
DE69933688T2 (de) * 1998-11-06 2007-08-23 Bayer Healthcare Ag G-protein-gekoppelter rezeptoren, die holomog zu ebv-induzierter gpcr (ebi-2) sind, verfahren zur identifizierung von ihren entsprechenden liganden
US6221660B1 (en) * 1999-02-22 2001-04-24 Synaptic Pharmaceutical Corporation DNA encoding SNORF25 receptor
US6689866B1 (en) * 1999-03-09 2004-02-10 Curagen Corporation Polynucleotides and proteins encoded thereby
US6590938B1 (en) * 1999-09-30 2003-07-08 Conexant Systems, Inc. DCT domain conversion of a higher definition signal to lower definition signal
GB9923177D0 (en) * 1999-09-30 1999-12-01 Pfizer Ltd Novel polypeptide

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AU3790400A (en) 2000-06-13
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NZ511087A (en) 2004-01-30
DK1584683T3 (da) 2007-10-29
KR100963367B1 (ko) 2010-06-14
EP1849866B1 (de) 2008-05-21
DK1133559T3 (da) 2006-04-10
EP2295572A1 (de) 2011-03-16
EP1780280A1 (de) 2007-05-02
JP2007209352A (ja) 2007-08-23
ATE366815T1 (de) 2007-08-15
KR20070097564A (ko) 2007-10-04
ATE301673T1 (de) 2005-08-15
EP1133559B1 (de) 2005-08-10
KR20010086040A (ko) 2001-09-07
EP1849866A2 (de) 2007-10-31
WO2000031258A3 (en) 2000-10-05
JP2008133300A (ja) 2008-06-12
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KR20080024234A (ko) 2008-03-17
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PT1584683E (pt) 2007-10-17
EP1580271A2 (de) 2005-09-28
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CA2348377A1 (en) 2000-06-02
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