ATE405660T1 - Verfahren zur insulinproduktion in pflanzen - Google Patents

Verfahren zur insulinproduktion in pflanzen

Info

Publication number
ATE405660T1
ATE405660T1 AT04737835T AT04737835T ATE405660T1 AT E405660 T1 ATE405660 T1 AT E405660T1 AT 04737835 T AT04737835 T AT 04737835T AT 04737835 T AT04737835 T AT 04737835T AT E405660 T1 ATE405660 T1 AT E405660T1
Authority
AT
Austria
Prior art keywords
plants
insulin production
insulin
production
Prior art date
Application number
AT04737835T
Other languages
English (en)
Inventor
Maurice Moloney
Joseph Boothe
Richard Keon
Cory Nykiforuk
Rooijen Gijs Van
Original Assignee
Sembiosys Genetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sembiosys Genetics Inc filed Critical Sembiosys Genetics Inc
Application granted granted Critical
Publication of ATE405660T1 publication Critical patent/ATE405660T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8257—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits for the production of primary gene products, e.g. pharmaceutical products, interferon
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01H—NEW PLANTS OR NON-TRANSGENIC PROCESSES FOR OBTAINING THEM; PLANT REPRODUCTION BY TISSUE CULTURE TECHNIQUES
    • A01H1/00—Processes for modifying genotypes ; Plants characterised by associated natural traits
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Endocrinology (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Diabetes (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Developmental Biology & Embryology (AREA)
  • Environmental Sciences (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT04737835T 2003-06-17 2004-06-17 Verfahren zur insulinproduktion in pflanzen ATE405660T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US47881803P 2003-06-17 2003-06-17
US54953904P 2004-03-04 2004-03-04

Publications (1)

Publication Number Publication Date
ATE405660T1 true ATE405660T1 (de) 2008-09-15

Family

ID=33555509

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04737835T ATE405660T1 (de) 2003-06-17 2004-06-17 Verfahren zur insulinproduktion in pflanzen

Country Status (23)

Country Link
US (2) US7547821B2 (de)
EP (2) EP1959017A1 (de)
JP (2) JP4864701B2 (de)
KR (1) KR101216762B1 (de)
CN (1) CN1836047B (de)
AR (1) AR044803A1 (de)
AT (1) ATE405660T1 (de)
AU (1) AU2004247762B2 (de)
BR (1) BRPI0411479A (de)
CA (1) CA2528741A1 (de)
CY (1) CY1108477T1 (de)
DE (1) DE602004015980D1 (de)
DK (1) DK1633876T3 (de)
EA (1) EA014887B1 (de)
ES (1) ES2313018T3 (de)
IL (1) IL172469A (de)
MX (1) MXPA05013723A (de)
NO (1) NO20055885L (de)
NZ (1) NZ544522A (de)
PL (1) PL1633876T3 (de)
PT (1) PT1633876E (de)
TW (1) TWI345587B (de)
WO (1) WO2004111244A2 (de)

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US8993516B2 (en) * 2008-04-14 2015-03-31 Case Western Reserve University Meal-time insulin analogues of enhanced stability
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CN102268451B (zh) * 2010-06-01 2014-03-12 安胜军 一种含有人胰岛素基因的表达载体及其构建方法与应用
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US9006176B2 (en) * 2011-10-18 2015-04-14 AmideBio LLC Chemically and thermodynamically stable insulin analogues and improved methods for their production
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US9163073B2 (en) 2013-04-17 2015-10-20 Amidebio, Llc Chemically and thermodynamically stable insulin analogues and improved methods for their production
KR101625746B1 (ko) 2013-09-23 2016-05-31 순천대학교 산학협력단 프로미니인슐린 재조합 단백질이 발현된 형질전환 식물 및 이의 제조방법
CA2961037A1 (en) 2014-10-06 2016-04-14 Case Western Reserve University Biphasic single-chain insulin analogues
US20220096607A1 (en) * 2015-04-09 2022-03-31 Kinetiq Therapeutics, Llc Subcutaneous therapeutic enzyme formulations, uses, and methods for generating thereof
ES2886837T3 (es) 2016-12-16 2021-12-21 Novo Nordisk As Composiciones farmacéuticas que contienen insulina
KR102642178B1 (ko) * 2017-08-08 2024-02-29 중앙대학교 산학협력단 돌연변이에 의해, 혈중 반감기 및 공수병 바이러스 중화 효능이 증대된 공수병 바이러스 중화 항체
US20210032307A1 (en) * 2018-02-09 2021-02-04 Jiangsu Hengrui Medicine Co., Ltd. Codon optimized precursor gene and signal peptide gene of human insulin analogue
EP3956355B1 (de) * 2019-04-19 2025-11-26 The Trustees of Indiana University Stabilisierung von prandialen oder basalen insulinanaloga durch eine interne diselenidbrücke
WO2021113136A1 (en) * 2019-12-06 2021-06-10 Dr. Mary Morris & Associates, Llc Methods and compositions for the treatment and prevention of type 1 diabetes
IL299545A (en) * 2020-07-03 2023-02-01 Kriya Therapeutics Inc Different insulin and glucokinase nucleic acids for the treatment of diabetes
EP4190905A1 (de) 2021-12-01 2023-06-07 Core Biogenesis Verfahren zur reinigung von rekombinanten proteinen unter verwendung von ölkörperproteinen

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Also Published As

Publication number Publication date
EP1633876B1 (de) 2008-08-20
IL172469A0 (en) 2006-04-10
JP4864701B2 (ja) 2012-02-01
PT1633876E (pt) 2008-11-03
KR101216762B1 (ko) 2013-01-02
EA200600050A1 (ru) 2006-06-30
DE602004015980D1 (de) 2008-10-02
US20050039235A1 (en) 2005-02-17
AU2004247762A1 (en) 2004-12-23
TWI345587B (en) 2011-07-21
NO20055885L (no) 2006-01-17
PL1633876T3 (pl) 2009-01-30
WO2004111244A3 (en) 2005-02-03
WO2004111244A2 (en) 2004-12-23
TW200510529A (en) 2005-03-16
MXPA05013723A (es) 2006-03-13
US20090282583A1 (en) 2009-11-12
AR044803A1 (es) 2005-10-05
JP2007523611A (ja) 2007-08-23
KR20060052705A (ko) 2006-05-19
EA014887B1 (ru) 2011-02-28
CA2528741A1 (en) 2004-12-23
BRPI0411479A (pt) 2006-07-25
EP1959017A1 (de) 2008-08-20
CY1108477T1 (el) 2014-04-09
ES2313018T3 (es) 2009-03-01
JP2011200251A (ja) 2011-10-13
CN1836047B (zh) 2010-12-22
IL172469A (en) 2011-08-31
HK1088037A1 (en) 2006-10-27
NZ544522A (en) 2008-03-28
US7547821B2 (en) 2009-06-16
CN1836047A (zh) 2006-09-20
DK1633876T3 (da) 2008-12-08
EP1633876A2 (de) 2006-03-15
AU2004247762B2 (en) 2010-05-27

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