ATE41034T1 - Herstellung von protein a. - Google Patents

Herstellung von protein a.

Info

Publication number
ATE41034T1
ATE41034T1 AT84302874T AT84302874T ATE41034T1 AT E41034 T1 ATE41034 T1 AT E41034T1 AT 84302874 T AT84302874 T AT 84302874T AT 84302874 T AT84302874 T AT 84302874T AT E41034 T1 ATE41034 T1 AT E41034T1
Authority
AT
Austria
Prior art keywords
protein
production
disclosed
methods
gram
Prior art date
Application number
AT84302874T
Other languages
English (en)
Inventor
Stephen R Fahnestock
Original Assignee
Genex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genex Corp filed Critical Genex Corp
Application granted granted Critical
Publication of ATE41034T1 publication Critical patent/ATE41034T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/75—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Bacillus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/839—Bacillus subtilis

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Mycology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
AT84302874T 1983-04-28 1984-04-27 Herstellung von protein a. ATE41034T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/489,326 US4617266A (en) 1983-04-28 1983-04-28 Production of Protein A
EP84302874A EP0124374B1 (de) 1983-04-28 1984-04-27 Herstellung von Protein A

Publications (1)

Publication Number Publication Date
ATE41034T1 true ATE41034T1 (de) 1989-03-15

Family

ID=23943384

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84302874T ATE41034T1 (de) 1983-04-28 1984-04-27 Herstellung von protein a.

Country Status (5)

Country Link
US (1) US4617266A (de)
EP (1) EP0124374B1 (de)
JP (1) JPS59205996A (de)
AT (1) ATE41034T1 (de)
DE (1) DE3476896D1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5151350A (en) * 1982-10-27 1992-09-29 Repligen Corporation Cloned genes encoding recombinant protein a
JPS59205983A (ja) * 1983-04-28 1984-11-21 ジエネツクス・コ−ポレイシヨン 異種遺伝子を原核微生物で発現させる方法
US4828994A (en) * 1984-09-21 1989-05-09 Genex Corporation Bacillus strains with reduced extracellular protease levels
US4691009A (en) * 1984-12-26 1987-09-01 Repligen Corporation Hybrid proteins produced by an ultrahigh prokaryotic expression system
SE459503B (sv) * 1985-05-03 1989-07-10 Excorim Kommanditbolag Hybrid-dna-molekyl innefattande dna-sekvens som kodar foer protein g samt foerfarande foer framstaellning av protein g
SE448190B (sv) * 1985-06-03 1987-01-26 Pharmacia Ab Sett att bestemma fc-dels-bindande bakteriella polypeptider
GB8519848D0 (en) * 1985-08-07 1985-09-11 Schweiz Rotes Kreuz Treatment of chronic inflammatory disease
WO1987002385A1 (en) * 1985-10-11 1987-04-23 Genetics Institute, Inc. Method for producing heterologous proteins
SE459662B (sv) * 1986-03-21 1989-07-24 Pharmacia Ab Hybrid-dna-molekyl som kodar foer ett protein med samma igg specificitet som protein g, plasmid innehaallande densamma samt foerfarande foer framstaellning av proteinet
US4931390A (en) * 1986-04-16 1990-06-05 Public Health Research Institute Of The City Of New York, Inc. Expression of the cloned lysostaphin gene
AU8270187A (en) * 1986-10-28 1988-05-25 Memorial Sloan-Kettering Cancer Center Dna expressing fc receptor protein
BR8805646A (pt) * 1987-02-27 1989-10-17 Gist Brocades Nv Processo para amplificacao de genes estaveis em adn cromossomico de microorganismos procarioticos
WO1988009343A1 (fr) * 1987-05-29 1988-12-01 Sagami Chemical Research Center Proteine fusionnee contenant une lymphotoxine
JPH01269492A (ja) * 1988-04-19 1989-10-26 Toyobo Co Ltd 耐熱性プロテアーゼの製造方法
JPH0740924B2 (ja) * 1990-08-22 1995-05-10 エム・ディ・リサーチ株式会社 形質転換体および融合蛋白質の製造方法
JPH0740926B2 (ja) * 1990-10-09 1995-05-10 エム・ディ・リサーチ株式会社 形質転換体およびペプチド前駆体タンパク質の製造方法
SE9704141D0 (sv) * 1997-11-12 1997-11-12 Sbl Vaccin Ab New protein and nucleotide sequence, encoding said protein
GB0011186D0 (en) * 2000-05-09 2000-06-28 Agrol Limited Modification of bacteria
US7211258B2 (en) * 2002-04-10 2007-05-01 Protalex, Inc. Protein A compositions and methods of use
US7425331B2 (en) * 2002-04-10 2008-09-16 Protalex, Inc. Protein A methods of use
EP2251425B1 (de) 2004-07-06 2016-04-20 Kaneka Corporation Verfahren zur Herstellung eines Protein-A-ähnlichen Proteins unter Verwendung eines Bakteriums der Gattung Brevibacillus
US7375188B2 (en) * 2005-07-29 2008-05-20 Mallinckrodt Baker, Inc. Vegetarian protein a preparation and methods thereof
US8592555B2 (en) * 2008-08-11 2013-11-26 Emd Millipore Corporation Immunoglobulin-binding proteins with improved specificity
SG195555A1 (en) * 2008-12-24 2013-12-30 Emd Millipore Corp Caustic stable chromatography ligands
SG186552A1 (en) 2011-06-08 2013-01-30 Emd Millipore Corp Chromatography matrices including novel staphylococcus aureus protein a based ligands
CN110872565A (zh) * 2018-08-31 2020-03-10 重庆市畜牧科学院 培养蜂毒肽重组质粒的枯草芽孢杆菌感受态细胞的培养基

Also Published As

Publication number Publication date
US4617266A (en) 1986-10-14
EP0124374A1 (de) 1984-11-07
EP0124374B1 (de) 1989-03-01
JPS59205996A (ja) 1984-11-21
DE3476896D1 (en) 1989-04-06

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee