ATE411280T1 - Phenoxyessigsäure-derivate zur behandlung von störungen der atemwege - Google Patents
Phenoxyessigsäure-derivate zur behandlung von störungen der atemwegeInfo
- Publication number
- ATE411280T1 ATE411280T1 AT04726045T AT04726045T ATE411280T1 AT E411280 T1 ATE411280 T1 AT E411280T1 AT 04726045 T AT04726045 T AT 04726045T AT 04726045 T AT04726045 T AT 04726045T AT E411280 T1 ATE411280 T1 AT E411280T1
- Authority
- AT
- Austria
- Prior art keywords
- respiratory disorders
- treatment
- acid derivatives
- phenoxyacetic acid
- disorders
- Prior art date
Links
- LCPDWSOZIOUXRV-UHFFFAOYSA-N phenoxyacetic acid Chemical class OC(=O)COC1=CC=CC=C1 LCPDWSOZIOUXRV-UHFFFAOYSA-N 0.000 title abstract 2
- 208000023504 respiratory system disease Diseases 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
- C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
- C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring
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Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0301009A SE0301009D0 (sv) | 2003-04-07 | 2003-04-07 | Novel compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE411280T1 true ATE411280T1 (de) | 2008-10-15 |
Family
ID=20290948
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04726045T ATE411280T1 (de) | 2003-04-07 | 2004-04-06 | Phenoxyessigsäure-derivate zur behandlung von störungen der atemwege |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20060211765A1 (de) |
| EP (1) | EP1636175B1 (de) |
| JP (1) | JP4588018B2 (de) |
| AT (1) | ATE411280T1 (de) |
| DE (1) | DE602004017174D1 (de) |
| ES (1) | ES2314389T3 (de) |
| SE (1) | SE0301009D0 (de) |
| WO (1) | WO2004089884A1 (de) |
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| SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| RU2387652C2 (ru) | 2004-03-11 | 2010-04-27 | Актелион Фармасьютиклз Лтд | Производные тетрагидропиридоиндола |
| BRPI0510043A (pt) * | 2004-04-20 | 2007-10-16 | Pfizer | método de tratamento de dor neuropática usando antagonista de receptor crth2 |
| GB0409921D0 (en) * | 2004-05-04 | 2004-06-09 | Novartis Ag | Organic compounds |
| GB0415320D0 (en) * | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| JP5208510B2 (ja) | 2004-11-23 | 2013-06-12 | アストラゼネカ・アクチエボラーグ | 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体 |
| KR101289995B1 (ko) | 2005-09-27 | 2013-07-26 | 시오노기 앤드 컴파니, 리미티드 | Pgd2 수용체 길항제 활성을 갖는 설폰아마이드 유도체 |
| JP5155171B2 (ja) | 2005-10-06 | 2013-02-27 | アストラゼネカ・アクチエボラーグ | 新規化合物 |
| RU2424229C2 (ru) * | 2005-10-06 | 2011-07-20 | Астразенека Аб | Производные бифенилоксиуксусной кислоты, их применение для изготовления лекарственного средства и промежуточные соединения |
| TW200745003A (en) * | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| GB0520324D0 (en) * | 2005-10-06 | 2005-11-16 | Astrazeneca Ab | Novel compounds |
| US20080255150A1 (en) * | 2005-11-05 | 2008-10-16 | Astrazeneca Ab | Novel Compounds |
| WO2007062678A1 (en) * | 2005-11-29 | 2007-06-07 | 7Tm Pharma A/S | Phenoxyacetic acid derivatives as crth2 receptor ligands |
| EP1963259B1 (de) * | 2005-12-15 | 2012-02-15 | AstraZeneca AB | Substituierte diphenylether, -amine, -sulfide und methane zur behandlung von atemwegserkrankungen |
| UA100983C2 (ru) * | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
| CA2707785C (en) | 2007-12-14 | 2015-11-03 | Pulmagen Therapeutics (Asthma) Limited | Indoles and their therapeutic use |
| WO2009089192A1 (en) * | 2008-01-07 | 2009-07-16 | Ligand Pharmaceuticals Inc. | 2-phenyl phenoxyacetic acids useful for treating inflammatory disorders |
| WO2009151910A2 (en) * | 2008-05-25 | 2009-12-17 | Wyeth | Combination product of receptor tyrosine kinase inhibitor and fatty acid synthase inhibitor for treating cancer |
| WO2010102154A2 (en) * | 2009-03-05 | 2010-09-10 | Ligand Pharmaceuticals Incorporated | Biaryl oxyacetic acid compounds |
| JP5800898B2 (ja) | 2010-07-05 | 2015-10-28 | アクテリオン ファーマシューティカルズ リミテッドActelion Pharmaceuticals Ltd | 1−フェニル−置換ヘテロシクリル誘導体及びプロスタグランジンd2受容体調節剤としてのそれらの使用 |
| EP2457900A1 (de) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | Neue Pyrazolderivate mit CRTH2-antagonistischem Verhalten |
| EP2526945A1 (de) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | Neue CRTH2-Antagonisten |
| EP2548876A1 (de) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | Neue CRTH2-Antagonisten |
| EP2548863A1 (de) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | Neue CRTH2-Antagonisten |
| SG11201402796SA (en) | 2011-12-16 | 2014-06-27 | Atopix Therapeutics Ltd | Combination of crth2 antagonist and a proton pump inhibitor for the treatment of eosinophilic esophagitis |
| RU2014129613A (ru) | 2011-12-21 | 2016-02-10 | Актелион Фармасьютиклз Лтд | Гетероциклильные производные и их применение в качестве модуляторов рецептора простагландина d2 |
| US9169270B2 (en) | 2012-07-05 | 2015-10-27 | Actelion Pharmaceuticals Ltd. | 1-phenyl-substituted heterocyclyl derivatives and their use as prostaglandin D2 receptor modulators |
| AU2014364327B2 (en) * | 2013-12-10 | 2021-03-04 | The Regents Of The University Of California | Differential diagnosis of liver disease |
| DK3307262T3 (da) | 2015-06-15 | 2021-08-09 | Nmd Pharma As | Forbindelser til anvendelse ved behandling af neuromuskulære lidelser |
| US11730714B2 (en) | 2017-12-14 | 2023-08-22 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
| US11591284B2 (en) | 2017-12-14 | 2023-02-28 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
| TWI794369B (zh) | 2017-12-14 | 2023-03-01 | 丹麥商Nmd藥品公司 | 用於治療神經肌肉病症的化合物 |
| US10385028B2 (en) | 2017-12-14 | 2019-08-20 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
| US11147788B2 (en) | 2017-12-14 | 2021-10-19 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
| TW201927738A (zh) | 2017-12-14 | 2019-07-16 | 丹麥商Nmd藥品公司 | 用於治療神經肌肉病症的化合物 |
| TWI780281B (zh) | 2017-12-14 | 2022-10-11 | 丹麥商Nmd藥品公司 | 用於治療神經肌肉病症的化合物 |
| US12415771B2 (en) | 2019-06-19 | 2025-09-16 | Nmd Pharma A/S | Compounds for the treatment of neuromuscular disorders |
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| JPS5239888B2 (de) * | 1973-05-28 | 1977-10-07 | ||
| US4670566A (en) * | 1979-07-12 | 1987-06-02 | A. H. Robins Company, Incorporated | 3-methyl-hio-4-(5-, 6-, or 7-)phenylindolindolin-2-ones |
| US5006542A (en) * | 1988-10-31 | 1991-04-09 | E. R. Squibb & Sons, Inc. | Arylthioalkylphenyl carboxylic acids, derivatives thereof, compositions containing same and method of use |
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| AU2003297398B2 (en) * | 2002-12-20 | 2009-09-24 | Amgen Inc. | Asthma and allergic inflammation modulators |
| AU2004232682B2 (en) * | 2003-03-28 | 2006-12-07 | Eli Lilly And Company | Isoquinoline-5-sulfonic acid amides as inhibitors of Akt (protein kinase B) |
| SE0301010D0 (sv) * | 2003-04-07 | 2003-04-07 | Astrazeneca Ab | Novel compounds |
| SA04250253B1 (ar) * | 2003-08-21 | 2009-11-10 | استرازينيكا ايه بي | احماض فينوكسي اسيتيك مستبدلة باعتبارها مركبات صيدلانية لعلاج الامراض التنفسية مثل الربو ومرض الانسداد الرئوي المزمن |
| US7166738B2 (en) * | 2004-04-23 | 2007-01-23 | Roche Palo Alto Llc | Non-nucleoside reverse transcriptase inhibitors |
| GB0415320D0 (en) * | 2004-07-08 | 2004-08-11 | Astrazeneca Ab | Novel compounds |
| GB0418830D0 (en) * | 2004-08-24 | 2004-09-22 | Astrazeneca Ab | Novel compounds |
| GB0422057D0 (en) * | 2004-10-05 | 2004-11-03 | Astrazeneca Ab | Novel compounds |
| JP5208510B2 (ja) * | 2004-11-23 | 2013-06-12 | アストラゼネカ・アクチエボラーグ | 呼吸器疾患の処置に有用なフェノキシ酢酸誘導体 |
| JP5155171B2 (ja) * | 2005-10-06 | 2013-02-27 | アストラゼネカ・アクチエボラーグ | 新規化合物 |
| TW200745003A (en) * | 2005-10-06 | 2007-12-16 | Astrazeneca Ab | Novel compounds |
| US20080255150A1 (en) * | 2005-11-05 | 2008-10-16 | Astrazeneca Ab | Novel Compounds |
| EP1963259B1 (de) * | 2005-12-15 | 2012-02-15 | AstraZeneca AB | Substituierte diphenylether, -amine, -sulfide und methane zur behandlung von atemwegserkrankungen |
| UA100983C2 (ru) * | 2007-07-05 | 2013-02-25 | Астразенека Аб | Бифенилоксипропановая кислота как модулятор crth2 и интермедиаты |
-
2003
- 2003-04-07 SE SE0301009A patent/SE0301009D0/xx unknown
-
2004
- 2004-04-06 DE DE602004017174T patent/DE602004017174D1/de not_active Expired - Lifetime
- 2004-04-06 JP JP2006508006A patent/JP4588018B2/ja not_active Expired - Fee Related
- 2004-04-06 ES ES04726045T patent/ES2314389T3/es not_active Expired - Lifetime
- 2004-04-06 EP EP04726045A patent/EP1636175B1/de not_active Expired - Lifetime
- 2004-04-06 US US10/552,082 patent/US20060211765A1/en not_active Abandoned
- 2004-04-06 WO PCT/SE2004/000534 patent/WO2004089884A1/en not_active Ceased
- 2004-04-06 AT AT04726045T patent/ATE411280T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1636175A1 (de) | 2006-03-22 |
| WO2004089884A1 (en) | 2004-10-21 |
| SE0301009D0 (sv) | 2003-04-07 |
| JP2006522117A (ja) | 2006-09-28 |
| JP4588018B2 (ja) | 2010-11-24 |
| ES2314389T3 (es) | 2009-03-16 |
| US20060211765A1 (en) | 2006-09-21 |
| DE602004017174D1 (de) | 2008-11-27 |
| EP1636175B1 (de) | 2008-10-15 |
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