ATE421512T1 - Inhibitoren von mitotischem kinesin - Google Patents
Inhibitoren von mitotischem kinesinInfo
- Publication number
- ATE421512T1 ATE421512T1 AT04780791T AT04780791T ATE421512T1 AT E421512 T1 ATE421512 T1 AT E421512T1 AT 04780791 T AT04780791 T AT 04780791T AT 04780791 T AT04780791 T AT 04780791T AT E421512 T1 ATE421512 T1 AT E421512T1
- Authority
- AT
- Austria
- Prior art keywords
- inhibitors
- mitotic kinesin
- compounds
- ksp kinesin
- treating
- Prior art date
Links
- 102000010638 Kinesin Human genes 0.000 title abstract 3
- 108010063296 Kinesin Proteins 0.000 title abstract 3
- 239000003112 inhibitor Substances 0.000 title 1
- 230000000394 mitotic effect Effects 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- RSEBUVRVKCANEP-UHFFFAOYSA-N 2-pyrroline Chemical class C1CC=CN1 RSEBUVRVKCANEP-UHFFFAOYSA-N 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000001413 cellular effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C04—CEMENTS; CONCRETE; ARTIFICIAL STONE; CERAMICS; REFRACTORIES
- C04B—LIME, MAGNESIA; SLAG; CEMENTS; COMPOSITIONS THEREOF, e.g. MORTARS, CONCRETE OR LIKE BUILDING MATERIALS; ARTIFICIAL STONE; CERAMICS; REFRACTORIES; TREATMENT OF NATURAL STONE
- C04B35/00—Shaped ceramic products characterised by their composition; Ceramics compositions; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/622—Forming processes; Processing powders of inorganic compounds preparatory to the manufacturing of ceramic products
- C04B35/626—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B
- C04B35/63—Preparing or treating the powders individually or as batches ; preparing or treating macroscopic reinforcing agents for ceramic products, e.g. fibres; mechanical aspects section B using additives specially adapted for forming the products, e.g.. binder binders
- C04B35/632—Organic additives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Ceramic Engineering (AREA)
- Manufacturing & Machinery (AREA)
- Structural Engineering (AREA)
- Inorganic Chemistry (AREA)
- Materials Engineering (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Transplantation (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US49563703P | 2003-08-15 | 2003-08-15 | |
| US56358004P | 2004-04-19 | 2004-04-19 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE421512T1 true ATE421512T1 (de) | 2009-02-15 |
Family
ID=34221386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04780791T ATE421512T1 (de) | 2003-08-15 | 2004-08-11 | Inhibitoren von mitotischem kinesin |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US20060234984A1 (de) |
| EP (1) | EP1664026B1 (de) |
| JP (1) | JP4773961B2 (de) |
| AT (1) | ATE421512T1 (de) |
| AU (1) | AU2004266232B2 (de) |
| CA (1) | CA2534065A1 (de) |
| CY (1) | CY1108927T1 (de) |
| DE (1) | DE602004019229D1 (de) |
| DK (1) | DK1664026T3 (de) |
| ES (1) | ES2319429T3 (de) |
| HR (1) | HRP20090195T1 (de) |
| PL (1) | PL1664026T3 (de) |
| PT (1) | PT1664026E (de) |
| SI (1) | SI1664026T1 (de) |
| WO (1) | WO2005019206A1 (de) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04012642A (es) * | 2002-06-14 | 2005-03-23 | Merck & Co Inc | Inhibidores de la cinesina mitotica. |
| ES2282647T3 (es) | 2002-06-14 | 2007-10-16 | MERCK & CO., INC. | Inhibidores de cinesina mitotica. |
| US20050182125A1 (en) * | 2003-05-16 | 2005-08-18 | Ambit Biosciences Corporation | Pyrrole compounds and uses thereof |
| US20040248972A1 (en) * | 2003-05-16 | 2004-12-09 | Ambit Biosciences Corporation | Compounds and uses thereof |
| US20040242673A1 (en) * | 2003-05-16 | 2004-12-02 | Ambit Biosciences Corporation | Heterocyclic compounds and uses thereof |
| AU2004266232B2 (en) * | 2003-08-15 | 2008-07-03 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
| US7666862B2 (en) | 2003-08-15 | 2010-02-23 | Merck & Co., Inc. | Mitotic Kinesin Inhibitors |
| AU2004264533B2 (en) | 2003-08-15 | 2009-01-22 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
| JP2007533762A (ja) * | 2004-04-19 | 2007-11-22 | メルク エンド カムパニー インコーポレーテッド | 2,2−二置換ピロールの調製方法 |
| JP2008505090A (ja) | 2004-07-01 | 2008-02-21 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害剤のプロドラッグ |
| US20100093767A1 (en) * | 2004-12-03 | 2010-04-15 | Takeda San Diego, Inc. | Mitotic Kinase Inhibitors |
| JP2008533144A (ja) * | 2005-03-16 | 2008-08-21 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害剤 |
| WO2006123182A2 (en) | 2005-05-17 | 2006-11-23 | Merck Sharp & Dohme Limited | Cyclohexyl sulphones for treatment of cancer |
| AR068888A1 (es) | 2007-10-19 | 2009-12-16 | Schering Corp | Derivados de 1, 3, 4 - tiadiazol, una composicion farmaceutica que los comprende y su uso en la preparacion de medicamentos para el tratamiento de enfermedades mediadas por la inhibicion de la quinesina ksp. |
| CN102123990B (zh) | 2008-06-19 | 2014-07-09 | 武田药品工业株式会社 | 杂环化合物及其用途 |
| WO2010114780A1 (en) | 2009-04-01 | 2010-10-07 | Merck Sharp & Dohme Corp. | Inhibitors of akt activity |
| US8859776B2 (en) | 2009-10-14 | 2014-10-14 | Merck Sharp & Dohme Corp. | Substituted piperidines that increase p53 activity and the uses thereof |
| US8999957B2 (en) | 2010-06-24 | 2015-04-07 | Merck Sharp & Dohme Corp. | Heterocyclic compounds as ERK inhibitors |
| CA2805265A1 (en) | 2010-08-02 | 2012-02-09 | Merck Sharp & Dohme Corp. | Rna interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (ctnnb1) gene expression using short interfering nucleic acid (sina) |
| WO2012024170A2 (en) | 2010-08-17 | 2012-02-23 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF HEPATITIS B VIRUS (HBV) GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACID (siNA) |
| WO2012030685A2 (en) | 2010-09-01 | 2012-03-08 | Schering Corporation | Indazole derivatives useful as erk inhibitors |
| WO2012058210A1 (en) | 2010-10-29 | 2012-05-03 | Merck Sharp & Dohme Corp. | RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA) |
| EP2654748B1 (de) | 2010-12-21 | 2016-07-27 | Merck Sharp & Dohme Corp. | Indazolderivate als erk-hemmer |
| WO2012116217A1 (en) * | 2011-02-25 | 2012-08-30 | Irm Llc | Compounds and compositions as trk inhibitors |
| EP2770987B1 (de) | 2011-10-27 | 2018-04-04 | Merck Sharp & Dohme Corp. | Neue verbindungen als erk-hemmer |
| WO2013165816A2 (en) | 2012-05-02 | 2013-11-07 | Merck Sharp & Dohme Corp. | SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS |
| WO2014052563A2 (en) | 2012-09-28 | 2014-04-03 | Merck Sharp & Dohme Corp. | Novel compounds that are erk inhibitors |
| ME02925B (de) | 2012-11-28 | 2018-04-20 | Merck Sharp & Dohme | Zusammensetzungen und verfahren zur behandlung von krebs |
| TW201429969A (zh) | 2012-12-20 | 2014-08-01 | Merck Sharp & Dohme | 作爲hdm2抑制劑之經取代咪唑吡啶 |
| WO2014120748A1 (en) | 2013-01-30 | 2014-08-07 | Merck Sharp & Dohme Corp. | 2,6,7,8 substituted purines as hdm2 inhibitors |
| US20160194368A1 (en) | 2013-09-03 | 2016-07-07 | Moderna Therapeutics, Inc. | Circular polynucleotides |
| CN104370939B (zh) * | 2014-10-14 | 2016-10-26 | 上海交通大学 | 一种手性二氢吡咯类化合物的制备方法 |
| JOP20190055A1 (ar) | 2016-09-26 | 2019-03-24 | Merck Sharp & Dohme | أجسام مضادة ضد cd27 |
| US10975084B2 (en) | 2016-10-12 | 2021-04-13 | Merck Sharp & Dohme Corp. | KDM5 inhibitors |
| CN118267470A (zh) | 2017-04-13 | 2024-07-02 | 赛罗帕私人有限公司 | 抗SIRPα抗体 |
| US10947234B2 (en) | 2017-11-08 | 2021-03-16 | Merck Sharp & Dohme Corp. | PRMT5 inhibitors |
| EP3706747B1 (de) | 2017-11-08 | 2025-09-03 | Merck Sharp & Dohme LLC | Prmt5-inhibitoren |
| WO2019148412A1 (en) | 2018-02-01 | 2019-08-08 | Merck Sharp & Dohme Corp. | Anti-pd-1/lag3 bispecific antibodies |
| WO2020033282A1 (en) | 2018-08-07 | 2020-02-13 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
| EP3833669A4 (de) | 2018-08-07 | 2022-05-11 | Merck Sharp & Dohme Corp. | Prmt5-inhibitoren |
| US11981701B2 (en) | 2018-08-07 | 2024-05-14 | Merck Sharp & Dohme Llc | PRMT5 inhibitors |
| WO2020033288A1 (en) | 2018-08-07 | 2020-02-13 | Merck Sharp & Dohme Corp. | Prmt5 inhibitors |
| CN115003303B (zh) | 2019-12-17 | 2024-03-08 | 默沙东公司 | Prmt5抑制剂 |
| JP7589247B2 (ja) | 2019-12-17 | 2024-11-25 | メルク・シャープ・アンド・ドーム・エルエルシー | Prmt5阻害剤 |
| EP4076460B1 (de) | 2019-12-17 | 2026-01-21 | Merck Sharp & Dohme LLC | 1,4-dihydro-2h-spiro[isoquinoline-3,4'-piperidin]-derivate als prmt5 inhibitoren zur behandlung von krebs |
| US12595248B2 (en) | 2019-12-17 | 2026-04-07 | Merck Sharp & Dohme Llc | PRMT5 inhibitors |
| KR20240135076A (ko) | 2021-08-10 | 2024-09-10 | 애브비 인코포레이티드 | 니코틴아미드 ripk1 억제제 |
| WO2026027944A1 (en) | 2024-07-30 | 2026-02-05 | Sairopa B.V. | Anti-sirp alpha antibody formulations and uses thereof |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3142699A (en) * | 1958-04-24 | 1964-07-28 | Bayer Ag | Urethane compounds and process therefor |
| US3647790A (en) * | 1969-04-08 | 1972-03-07 | American Home Prod | Ouinoxalinyl-oxazolidines and -oxazines |
| US4477389A (en) * | 1982-10-25 | 1984-10-16 | The United States Of America As Represented By The Secretary Of Agriculture | Polyhalogenated phenyl isocyanate synthesis with excess phosgene and either triethylamine or tetramethylurea |
| GB9206757D0 (en) | 1992-03-27 | 1992-05-13 | Ferring Bv | Novel peptide receptor ligands |
| AU4064597A (en) | 1996-08-16 | 1998-03-06 | Du Pont Pharmaceuticals Company | Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof |
| US6057342A (en) * | 1996-08-16 | 2000-05-02 | Dupont Pharmaceutical Co. | Amidinophenyl-pyrrolidines, -pyrrolines, and -isoxazolidines and derivatives thereof |
| US6440686B1 (en) | 2000-06-15 | 2002-08-27 | Cytokinetics, Inc. | Methods for screening and therapeutic applications of kinesin modulators |
| AU2002363960B2 (en) | 2001-12-06 | 2008-07-10 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
| JP2003177052A (ja) * | 2001-12-13 | 2003-06-27 | Takata Corp | シート重量計測装置 |
| EP1492487B1 (de) * | 2002-03-08 | 2009-11-11 | Merck & Co., Inc. | Mitotische kinesin-hemmer |
| WO2004039774A2 (en) * | 2002-05-23 | 2004-05-13 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
| JP2005530806A (ja) * | 2002-05-23 | 2005-10-13 | メルク エンド カムパニー インコーポレーテッド | 有糸分裂キネシン阻害薬 |
| MXPA04012642A (es) * | 2002-06-14 | 2005-03-23 | Merck & Co Inc | Inhibidores de la cinesina mitotica. |
| ES2282647T3 (es) | 2002-06-14 | 2007-10-16 | MERCK & CO., INC. | Inhibidores de cinesina mitotica. |
| US6835899B2 (en) * | 2002-08-21 | 2004-12-28 | Trw Inc. | Load sensing assembly for a vehicle seat |
| EP1556052A4 (de) | 2002-10-18 | 2006-11-02 | Merck & Co Inc | Mitotische kinesin-hemmer |
| ATE426605T1 (de) * | 2003-06-12 | 2009-04-15 | Merck & Co Inc | Inhibitoren von mitotischem kinesin |
| EP1636182A4 (de) * | 2003-06-12 | 2008-09-03 | Merck & Co Inc | Prodrugs von inhibitoren vom mitotischem kinesin |
| EP1656140A4 (de) * | 2003-08-13 | 2009-03-04 | Merck & Co Inc | Inhibitoren von mitotischem kinesin |
| AU2004266232B2 (en) * | 2003-08-15 | 2008-07-03 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
| AU2004264533B2 (en) * | 2003-08-15 | 2009-01-22 | Merck Sharp & Dohme Corp. | Mitotic kinesin inhibitors |
| PE20050730A1 (es) * | 2003-08-15 | 2005-09-20 | Merck & Co Inc | Derivados de 2,5-dihidropirrol 2,2-disustituidos como inhibidores de quinesinas mitoticas |
| US7294640B2 (en) * | 2004-02-06 | 2007-11-13 | Merck & Co., Inc. | Mitotic kinesin inhibitors |
-
2004
- 2004-08-11 AU AU2004266232A patent/AU2004266232B2/en not_active Ceased
- 2004-08-11 HR HR20090195T patent/HRP20090195T1/xx unknown
- 2004-08-11 PT PT04780791T patent/PT1664026E/pt unknown
- 2004-08-11 JP JP2006523332A patent/JP4773961B2/ja not_active Expired - Fee Related
- 2004-08-11 DE DE602004019229T patent/DE602004019229D1/de not_active Expired - Lifetime
- 2004-08-11 ES ES04780791T patent/ES2319429T3/es not_active Expired - Lifetime
- 2004-08-11 PL PL04780791T patent/PL1664026T3/pl unknown
- 2004-08-11 AT AT04780791T patent/ATE421512T1/de active
- 2004-08-11 US US10/567,676 patent/US20060234984A1/en not_active Abandoned
- 2004-08-11 EP EP04780791A patent/EP1664026B1/de not_active Expired - Lifetime
- 2004-08-11 CA CA002534065A patent/CA2534065A1/en not_active Abandoned
- 2004-08-11 US US10/915,743 patent/US7465746B2/en not_active Expired - Fee Related
- 2004-08-11 DK DK04780791T patent/DK1664026T3/da active
- 2004-08-11 WO PCT/US2004/026012 patent/WO2005019206A1/en not_active Ceased
- 2004-08-11 SI SI200431039T patent/SI1664026T1/sl unknown
-
2009
- 2009-03-30 CY CY20091100367T patent/CY1108927T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20060234984A1 (en) | 2006-10-19 |
| JP2007502774A (ja) | 2007-02-15 |
| SI1664026T1 (sl) | 2009-04-30 |
| US7465746B2 (en) | 2008-12-16 |
| CY1108927T1 (el) | 2014-07-02 |
| DE602004019229D1 (de) | 2009-03-12 |
| CA2534065A1 (en) | 2005-03-03 |
| PT1664026E (pt) | 2009-04-23 |
| PL1664026T3 (pl) | 2009-06-30 |
| ES2319429T3 (es) | 2009-05-07 |
| US20050043357A1 (en) | 2005-02-24 |
| WO2005019206A1 (en) | 2005-03-03 |
| AU2004266232A1 (en) | 2005-03-03 |
| DK1664026T3 (da) | 2009-05-04 |
| EP1664026B1 (de) | 2009-01-21 |
| JP4773961B2 (ja) | 2011-09-14 |
| HRP20090195T1 (hr) | 2009-05-31 |
| EP1664026A1 (de) | 2006-06-07 |
| AU2004266232B2 (en) | 2008-07-03 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE421512T1 (de) | Inhibitoren von mitotischem kinesin | |
| ATE446094T1 (de) | Mitotische kinesin-hemmer | |
| DE60312516D1 (de) | Inhibitoren von mitotischem kinesin | |
| ATE372341T1 (de) | Inhibitoren von mitotischem kinesin | |
| ATE448207T1 (de) | Mitotische kinesin-hemmer | |
| ATE424388T1 (de) | Mitotische kinesinhemmer | |
| ATE447577T1 (de) | Mitotische kinesin-hemmer | |
| WO2005017190A3 (en) | Mitotic kinesin inhibitors | |
| WO2004037171A3 (en) | Mitotic kinesin inhibitors | |
| WO2005018547A3 (en) | Mitotic kinesin inhibitors | |
| WO2004039774A3 (en) | Mitotic kinesin inhibitors | |
| WO2003099211A3 (en) | Mitotic kinesin inhibitors | |
| ECSP066362A (es) | Inhibidores de quinesina mitótica. | |
| WO2004058700A3 (en) | Mitotic kinesin inhibitors | |
| WO2004058148A3 (en) | Mitotic kinesin inhibitors | |
| WO2005060654A3 (en) | Mitotic kinesin inhibitors | |
| WO2005065183A3 (en) | Mitotic kinesin inhibitors | |
| NO20070589L (no) | Mitotiske kinesin-inhibitorer. | |
| ATE426605T1 (de) | Inhibitoren von mitotischem kinesin | |
| WO2006023440A3 (en) | Mitotic kinesin inhibitors | |
| WO2004087050A3 (en) | Mitotic kinesin inhibitors |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1664026 Country of ref document: EP |
|
| EEFA | Change of the company name |