NO20074884L - Kinolinonforbindelser som 5-HT receptoragonister - Google Patents

Kinolinonforbindelser som 5-HT receptoragonister

Info

Publication number
NO20074884L
NO20074884L NO20074884A NO20074884A NO20074884L NO 20074884 L NO20074884 L NO 20074884L NO 20074884 A NO20074884 A NO 20074884A NO 20074884 A NO20074884 A NO 20074884A NO 20074884 L NO20074884 L NO 20074884L
Authority
NO
Norway
Prior art keywords
compounds
receptor agonists
quinolinone compounds
methods
quinolinone
Prior art date
Application number
NO20074884A
Other languages
English (en)
Inventor
Paul Ross Fatheree
Daniel Marquess
Seok-Ki Choi
Roland Gendron
Derek S Turner
Adam A Goldblum
Lan Jiang
Daniel D Long
Original Assignee
Theravance Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theravance Inc filed Critical Theravance Inc
Publication of NO20074884L publication Critical patent/NO20074884L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Nye kinolinon-karboksamid 5-HT4-reseptoragonistforbindelser. Oppfinnelsen tilveiebringer også farmasøytiske preparater som innbefatter slike forbindelser, metoder for anvendelse av slike forbindelser til behandling av sykdommer som er forbundet med 5-HT4-reseptoraktivitet, og fremgangsmåter og mellomprodukter som er nyttige for fremstilling av slike forbindelser.
NO20074884A 2005-03-02 2007-09-25 Kinolinonforbindelser som 5-HT receptoragonister NO20074884L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US65800705P 2005-03-02 2005-03-02
PCT/US2006/007284 WO2006094063A1 (en) 2005-03-02 2006-03-01 Quinolinone compounds as 5-ht4 receptor agonists

Publications (1)

Publication Number Publication Date
NO20074884L true NO20074884L (no) 2007-11-29

Family

ID=36588769

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20074884A NO20074884L (no) 2005-03-02 2007-09-25 Kinolinonforbindelser som 5-HT receptoragonister

Country Status (16)

Country Link
US (2) US7446114B2 (no)
EP (1) EP1871772B1 (no)
JP (1) JP5042043B2 (no)
KR (1) KR20070107807A (no)
CN (1) CN101163701A (no)
AU (1) AU2006218603A1 (no)
BR (1) BRPI0608392A2 (no)
CA (1) CA2599404A1 (no)
EA (1) EA013567B1 (no)
ES (1) ES2523851T3 (no)
IL (1) IL185407A0 (no)
MX (1) MX2007010769A (no)
NO (1) NO20074884L (no)
NZ (1) NZ560828A (no)
WO (1) WO2006094063A1 (no)
ZA (1) ZA200707142B (no)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
TWI377206B (en) 2005-04-06 2012-11-21 Theravance Inc Crystalline form of a quinolinone-carboxamide compound
MY143574A (en) * 2005-11-22 2011-05-31 Theravance Inc Carbamate compounds as 5-ht4 receptor agonists
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
WO2008102720A1 (ja) * 2007-02-19 2008-08-28 Kaneka Corporation 光学活性３－アミノピペリジン又はその塩の製造方法
AU2009352490B2 (en) * 2009-09-14 2013-06-20 Suven Life Sciences Limited 1, 2-dihydro-2-oxoquinoline compounds as 5-HT 4 receptor ligands
WO2016161069A1 (en) 2015-04-02 2016-10-06 Theravance Biopharma R&D Ip, Llc Combination dosage form of a mu opioid receptor antagonist and an opioid agent
DK4463457T3 (da) 2022-01-11 2026-03-02 Suven Life Sciences Ltd Pyrrolo[1,2-b]-2-pyridazinonforbindelser som 5-ht4-receptoragonister

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Also Published As

Publication number Publication date
BRPI0608392A2 (pt) 2009-12-29
US7446114B2 (en) 2008-11-04
WO2006094063A1 (en) 2006-09-08
US20090036483A1 (en) 2009-02-05
JP2008531711A (ja) 2008-08-14
EA013567B1 (ru) 2010-06-30
ES2523851T3 (es) 2014-12-02
NZ560828A (en) 2011-01-28
AU2006218603A1 (en) 2006-09-08
CN101163701A (zh) 2008-04-16
EP1871772B1 (en) 2014-09-10
US20060199839A1 (en) 2006-09-07
ZA200707142B (en) 2008-10-29
JP5042043B2 (ja) 2012-10-03
US7875629B2 (en) 2011-01-25
EP1871772A1 (en) 2008-01-02
KR20070107807A (ko) 2007-11-07
MX2007010769A (es) 2008-03-07
EA200701867A1 (ru) 2008-02-28
CA2599404A1 (en) 2006-09-08
IL185407A0 (en) 2008-01-06

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