ATE441860T1 - Verfahren und kits zur messung von adamts13/fxi- komplexen - Google Patents

Verfahren und kits zur messung von adamts13/fxi- komplexen

Info

Publication number
ATE441860T1
ATE441860T1 AT05736096T AT05736096T ATE441860T1 AT E441860 T1 ATE441860 T1 AT E441860T1 AT 05736096 T AT05736096 T AT 05736096T AT 05736096 T AT05736096 T AT 05736096T AT E441860 T1 ATE441860 T1 AT E441860T1
Authority
AT
Austria
Prior art keywords
adamts13
kits
measurement
fxi complexes
assays
Prior art date
Application number
AT05736096T
Other languages
English (en)
Inventor
Robert Greenfield
Enriqueta Guinto
Safi Ranzurmal
Nicholas Grafos
Original Assignee
American Diagnostica Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Diagnostica Inc filed Critical American Diagnostica Inc
Application granted granted Critical
Publication of ATE441860T1 publication Critical patent/ATE441860T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00—N-linked chromogens for determinations of peptidases and proteinases

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT05736096T 2004-07-19 2005-04-15 Verfahren und kits zur messung von adamts13/fxi- komplexen ATE441860T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/894,702 US7270976B2 (en) 2004-07-19 2004-07-19 Methods for measuring ADAMTS13 activity and protein on platelets and in plasma
PCT/US2005/012964 WO2006019431A2 (en) 2004-07-19 2005-04-15 Methods and kits for measuring adamts13/fxi complexes

Publications (1)

Publication Number Publication Date
ATE441860T1 true ATE441860T1 (de) 2009-09-15

Family

ID=35599932

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05736096T ATE441860T1 (de) 2004-07-19 2005-04-15 Verfahren und kits zur messung von adamts13/fxi- komplexen

Country Status (6)

Country Link
US (2) US7270976B2 (de)
EP (1) EP1774327B1 (de)
AT (1) ATE441860T1 (de)
DE (1) DE602005016420D1 (de)
ES (1) ES2335022T3 (de)
WO (1) WO2006019431A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080138837A1 (en) * 2004-07-19 2008-06-12 Robert Greenfield Methods and kits for detecting and measuring ADAMTS13/FXI complexes
AU2008259839A1 (en) * 2007-05-31 2008-12-11 The Children's Hospital Of Philadelphia Compositions and methods for modulation of ADAMTS13 activity
KR101670103B1 (ko) 2008-12-05 2016-10-27 박스알타 인코퍼레이티드 폰빌레브란트 인자의 ａｄａｍｔｓ１３－매개 생체내 절단을 측정하는 방법 및 그의 사용
TR201904662T4 (tr) 2008-12-18 2019-05-21 Gruber Andras Anti-fxı antikorları ve kullanma yöntemleri.
US8945895B2 (en) 2009-07-31 2015-02-03 Baxter International Inc. Methods of purifying recombinant ADAMTS13 and other proteins and compositions thereof
EP2847228B1 (de) 2012-05-10 2018-07-25 Bayer Pharma Aktiengesellschaft Zur bindung an den gerinnungsfaktor xi und/oder dessen aktivierten form faktor xia fähige antikörper und verwendungen davon
NL2013007B1 (en) 2014-06-16 2016-07-05 Ablynx Nv Methods of treating TTP with immunoglobulin single variable domains and uses thereof.
MY204220A (en) 2018-02-06 2024-08-16 Ablynx Nv Methods of treating initial episode of ttp with immunoglobulin single variable domains
US20200186636A1 (en) * 2018-12-06 2020-06-11 Cisco Technology, Inc. Enabling call transfer using headset
CN110357957B (zh) * 2019-07-16 2021-04-02 湖南大学深圳研究院 一种制备ADAMTSL-3/punctin-2多克隆抗体的方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5340934A (en) * 1989-11-03 1994-08-23 The United States Of Americas As Represented By The Secretary Of Health & Human Services CDNA sequences of human bone matrix proteins
US6242246B1 (en) * 1997-12-15 2001-06-05 Somalogic, Inc. Nucleic acid ligand diagnostic Biochip
US20030083231A1 (en) * 1998-11-24 2003-05-01 Ahlem Clarence N. Blood cell deficiency treatment method
US7011952B2 (en) * 2000-02-22 2006-03-14 University Of Iowa Research Foundation Diagnostics and therapeutics for macular degeneration-related disorders
US20010049106A1 (en) * 2000-04-27 2001-12-06 Leonard Buckbinder ADAMTS polypeptides, nucleic acids encoding them, and uses thereof
US6926894B2 (en) * 2000-11-22 2005-08-09 Baxter Aktiengesellschaft Composition exhibiting a von willebrand factor (vWF) protease activity comprising a polypeptide chain with the amino acid sequence AAGGILHLELLV
JP2003284570A (ja) * 2001-04-25 2003-10-07 Chemo Sero Therapeut Res Inst フォンビルブラント因子（ｖＷＦ）切断酵素
US20030002231A1 (en) * 2001-06-29 2003-01-02 Dee Richard Henry Reduced sensitivity spin valve head for magnetic tape applications
US7037658B2 (en) * 2001-08-16 2006-05-02 Regents Of University Of Michigan Methods and compositions for detecting variant ADAMTS13 genes
EP1304557A1 (de) 2001-10-17 2003-04-23 Agilent Technologies, Inc. (a Delaware corporation) Verfahren zur Durchführung flusszytometrischer Messungen und Vorrichtung zur Durchführung des Verfahrens
US20040138187A1 (en) * 2002-08-28 2004-07-15 Reading Christopher L. Therapeutic treatment methods
JP3944586B2 (ja) 2002-10-18 2007-07-11 国立循環器病センター総長 フォンビルブランド因子切断酵素の特異的基質および活性測定法
US7763430B2 (en) * 2003-04-22 2010-07-27 Baxter International Inc. Diagnostic assay for anti-von Willebrand Factor cleaving protease (ADAMTS13) antibodies
CN1898567A (zh) * 2003-12-22 2007-01-17 株式会社三菱化学药得论 通过测定冯维勒布兰德因子分解酶检测血栓症的方法
US20050186646A1 (en) * 2004-01-26 2005-08-25 Cruz Miguel A. Rapid assay to detect ADAMTS-13 activity

Also Published As

Publication number Publication date
US20060073535A1 (en) 2006-04-06
ES2335022T3 (es) 2010-03-18
EP1774327B1 (de) 2009-09-02
US7270976B2 (en) 2007-09-18
DE602005016420D1 (de) 2009-10-15
EP1774327A4 (de) 2008-07-09
EP1774327A2 (de) 2007-04-18
US20060014233A1 (en) 2006-01-19
WO2006019431A2 (en) 2006-02-23
WO2006019431A3 (en) 2006-07-20

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