ATE457987T1 - Verfahren zur herstellung von 9-[4-acetoxy-3- (acetoxymethyl)but-1-yl -2-aminopurin - Google Patents

Verfahren zur herstellung von 9-[4-acetoxy-3- (acetoxymethyl)but-1-yl -2-aminopurin

Info

Publication number: ATE457987T1
Authority: AT; Austria
Prior art keywords: aminopurine; acetoxymethyl; acetoxy; producing; desired compound
Prior art date: 2002-07-15

Application number

AT03741578T

Other languages

English (en)

Inventor

Byoung-Suk Lee

Sang-Hoon Shin

Jong-Sik Park

Original Assignee

Kyungdong Pharm Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-15

Filing date

2003-07-15

Publication date

2010-03-15

2003-07-15 Application filed by Kyungdong Pharm Co Ltd filed Critical Kyungdong Pharm Co Ltd

2010-03-15 Application granted granted Critical

2010-03-15 Publication of ATE457987T1 publication Critical patent/ATE457987T1/de

Links

238000004519 manufacturing process Methods 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
GGXKWVWZWMLJEH-UHFFFAOYSA-N famcyclovir Chemical compound N1=C(N)N=C2N(CCC(COC(=O)C)COC(C)=O)C=NC2=C1 GGXKWVWZWMLJEH-UHFFFAOYSA-N 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
BKVIYDNLLOSFOA-UHFFFAOYSA-N thallium Chemical compound [Tl] BKVIYDNLLOSFOA-UHFFFAOYSA-N 0.000 abstract 2
MWBWWFOAEOYUST-UHFFFAOYSA-N 2-aminopurine Chemical compound NC1=NC=C2N=CNC2=N1 MWBWWFOAEOYUST-UHFFFAOYSA-N 0.000 abstract 1
AAVYTSAUFAJNDC-UHFFFAOYSA-N [2-(acetyloxymethyl)-4-bromobutyl] acetate Chemical compound CC(=O)OCC(CCBr)COC(C)=O AAVYTSAUFAJNDC-UHFFFAOYSA-N 0.000 abstract 1
230000000840 anti-viral effect Effects 0.000 abstract 1
229940079593 drug Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
HHFAWKCIHAUFRX-UHFFFAOYSA-N ethoxide Chemical compound CC[O-] HHFAWKCIHAUFRX-UHFFFAOYSA-N 0.000 abstract 1
229960004396 famciclovir Drugs 0.000 abstract 1
229940083251 peripheral vasodilators purine derivative Drugs 0.000 abstract 1
150000003212 purines Chemical class 0.000 abstract 1
229910052716 thallium Inorganic materials 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
Virology (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT03741578T 2002-07-15 2003-07-15 Verfahren zur herstellung von 9-[4-acetoxy-3- (acetoxymethyl)but-1-yl -2-aminopurin ATE457987T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR1020020041267A KR100573859B1 (ko)	2002-07-15	2002-07-15	9-[4-아세톡시-3-(아세톡시메틸)부트-1-일]-2-아미노푸린의제조방법
PCT/KR2003/001396 WO2004007497A1 (en)	2002-07-15	2003-07-15	Process for preparing 9-[4-acetoxy-3-(acetoxymethyl)but-1-yl]-2-aminopurine

Publications (1)

Publication Number	Publication Date
ATE457987T1 true ATE457987T1 (de)	2010-03-15

Family

ID=30113179

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03741578T ATE457987T1 (de)	2002-07-15	2003-07-15	Verfahren zur herstellung von 9-[4-acetoxy-3- (acetoxymethyl)but-1-yl -2-aminopurin

Country Status (8)

Country	Link
US (1)	US7041823B2 (de)
EP (1)	EP1551839B1 (de)
JP (1)	JP4231479B2 (de)
KR (1)	KR100573859B1 (de)
AT (1)	ATE457987T1 (de)
AU (1)	AU2003281046B8 (de)
DE (1)	DE60331334D1 (de)
WO (1)	WO2004007497A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
KR100573861B1 (ko) *	2003-07-18	2006-04-25	경동제약 주식회사	2-아미노-9-(2-할로게노에틸)푸린 및 그 중간체로서의 2-아미노-6,8-디클로로-9-(2-히드록시에틸)푸린의 제조방법
EP2850733B1 (de)	2012-05-13	2017-11-29	Amir Khandani	Drahtlose vollduplex-übertragung mit selbstinterferenzunterdrückung
CN102977171A (zh) *	2012-12-18	2013-03-20	吉林大学	一种五元杂环修饰的4′-螺环核苷化合物及在抗病毒中的应用
US10177896B2 (en)	2013-05-13	2019-01-08	Amir Keyvan Khandani	Methods for training of full-duplex wireless systems
US9236996B2 (en)	2013-11-30	2016-01-12	Amir Keyvan Khandani	Wireless full-duplex system and method using sideband test signals
US9820311B2 (en)	2014-01-30	2017-11-14	Amir Keyvan Khandani	Adapter and associated method for full-duplex wireless communication
US10778295B2 (en)	2016-05-02	2020-09-15	Amir Keyvan Khandani	Instantaneous beamforming exploiting user physical signatures
US10700766B2 (en)	2017-04-19	2020-06-30	Amir Keyvan Khandani	Noise cancelling amplify-and-forward (in-band) relay with self-interference cancellation
US11212089B2 (en)	2017-10-04	2021-12-28	Amir Keyvan Khandani	Methods for secure data storage
US11012144B2 (en)	2018-01-16	2021-05-18	Amir Keyvan Khandani	System and methods for in-band relaying

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3626018A (en) *	1968-01-25	1971-12-07	Edward C Taylor	Chemical processes using organothallium compounds
US4020073A (en) *	1971-02-04	1977-04-26	Taylor Edward C	Process for O-acylating thallus salts of 2-pyridone
US5684153A (en) *	1984-08-16	1997-11-04	Beecham Group Plc	Process for the preparation of purine derivatives
GB8822236D0 (en) *	1988-09-21	1988-10-26	Beecham Group Plc	Chemical process
GB9402161D0 (en) *	1994-02-04	1994-03-30	Wellcome Found	Chloropyrimidine intermediates

2002
- 2002-07-15 KR KR1020020041267A patent/KR100573859B1/ko not_active Expired - Fee Related
2003
- 2003-07-15 DE DE60331334T patent/DE60331334D1/de not_active Expired - Fee Related
- 2003-07-15 WO PCT/KR2003/001396 patent/WO2004007497A1/en not_active Ceased
- 2003-07-15 EP EP03741578A patent/EP1551839B1/de not_active Expired - Lifetime
- 2003-07-15 AU AU2003281046A patent/AU2003281046B8/en not_active Ceased
- 2003-07-15 US US10/521,352 patent/US7041823B2/en not_active Expired - Lifetime
- 2003-07-15 AT AT03741578T patent/ATE457987T1/de not_active IP Right Cessation
- 2003-07-15 JP JP2004521270A patent/JP4231479B2/ja not_active Expired - Fee Related

Also Published As

Publication number	Publication date
KR100573859B1 (ko)	2006-04-25
JP2005535672A (ja)	2005-11-24
EP1551839B1 (de)	2010-02-17
AU2003281046B8 (en)	2009-02-26
WO2004007497A1 (en)	2004-01-22
EP1551839A1 (de)	2005-07-13
US7041823B2 (en)	2006-05-09
KR20040007978A (ko)	2004-01-28
AU2003281046A1 (en)	2004-02-02
US20050222413A1 (en)	2005-10-06
JP4231479B2 (ja)	2009-02-25
AU2003281046B2 (en)	2009-02-19
DE60331334D1 (de)	2010-04-01

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Legal Events

Date	Code	Title	Description
2010-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties