ATE461935T1 - Verfahren zur reinigung von stark anionischen proteinen - Google Patents

Verfahren zur reinigung von stark anionischen proteinen

Info

Publication number: ATE461935T1
Authority: AT; Austria
Prior art keywords: purifying; proteins; sulfations; sulfated; anionic proteins
Prior art date: 2000-03-27

Application number

AT06006739T

Other languages

English (en)

Inventor

Jonathan L Coffman

William Barry Foster

Bonnie J Germain

Shujun Sun

Jeffrey J Robinson

Original Assignee

Genetics Inst Llc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-27

Filing date

2001-03-27

Publication date

2010-04-15

2001-03-27 Application filed by Genetics Inst Llc filed Critical Genetics Inst Llc

2010-04-15 Application granted granted Critical

2010-04-15 Publication of ATE461935T1 publication Critical patent/ATE461935T1/de

Links

238000000034 method Methods 0.000 title abstract 2
108090000623 proteins and genes Proteins 0.000 title abstract 2
102000004169 proteins and genes Human genes 0.000 title abstract 2
108091005994 sulfated proteins Proteins 0.000 abstract 3
230000019635 sulfation Effects 0.000 abstract 3
238000005670 sulfation reaction Methods 0.000 abstract 3
102000008212 P-Selectin Human genes 0.000 abstract 1
108010035766 P-Selectin Proteins 0.000 abstract 1
125000000129 anionic group Chemical group 0.000 abstract 1
-1 for example Proteins 0.000 abstract 1
239000003446 ligand Substances 0.000 abstract 1
125000001493 tyrosinyl group Chemical group [H]OC1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/18—Ion-exchange chromatography
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Analytical Chemistry (AREA)
Cell Biology (AREA)
Immunology (AREA)
Toxicology (AREA)
Zoology (AREA)
Gastroenterology & Hepatology (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Detergent Compositions (AREA)

AT06006739T 2000-03-27 2001-03-27 Verfahren zur reinigung von stark anionischen proteinen ATE461935T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US19335100P	2000-03-27	2000-03-27

Publications (1)

Publication Number	Publication Date
ATE461935T1 true ATE461935T1 (de)	2010-04-15

Family

ID=22713294

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
AT01922750T ATE328895T1 (de)	2000-03-27	2001-03-27	Methoden zur reinigung von stark anionischen proteinen
AT06006739T ATE461935T1 (de)	2000-03-27	2001-03-27	Verfahren zur reinigung von stark anionischen proteinen
AT06006740T ATE448241T1 (de)	2000-03-27	2001-03-27	Verfahren zur reinigung stark anionischer proteine

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT01922750T ATE328895T1 (de)	2000-03-27	2001-03-27	Methoden zur reinigung von stark anionischen proteinen

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
AT06006740T ATE448241T1 (de)	2000-03-27	2001-03-27	Verfahren zur reinigung stark anionischer proteine

Country Status (11)

Country	Link
US (1)	US6933370B2 (de)
EP (3)	EP1681299B1 (de)
JP (2)	JP5025874B2 (de)
AT (3)	ATE328895T1 (de)
AU (2)	AU2001249515B2 (de)
CA (1)	CA2404155C (de)
DE (3)	DE60140493D1 (de)
DK (3)	DK1268514T3 (de)
ES (3)	ES2343023T3 (de)
NZ (1)	NZ521578A (de)
WO (1)	WO2001072769A2 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO2002098531A1 (en) *	2001-06-05	2002-12-12	Genetics Institute, Llc	Methods for purifying highly anionic proteins
AU2003233008B2 (en) *	2002-04-22	2008-04-24	Recopharma Ab	Fusion polypeptides and methods for inhibiting microbial adhesion
DE602004026343D1 (de)	2003-10-24	2010-05-12	Amgen Inc	Verfahren zur aufreinigung von proteinen in einer durchflussfraktion aus der chromatographie mit hydrophoben wechselwirkungen
US7651690B2 (en) *	2005-06-24	2010-01-26	Desert Lake Technologies	Purified component of blue-green algae and method of use
AR058568A1 (es)	2005-12-20	2008-02-13	Bristol Myers Squibb Co	Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo
AU2006330922B2 (en) *	2005-12-20	2012-07-26	Bristol-Myers Squibb Company	Compositions and methods for producing a composition
EP2089429B1 (de) *	2006-10-19	2014-11-26	Janssen Biotech, Inc.	Verfahren zur herstellung nicht aggregierter antikörper-fc-domänen
EP2519537A4 (de) *	2009-12-29	2013-07-10	Reddys Lab Ltd Dr	Reinigung von proteinen
MX2012009283A (es)	2010-02-12	2012-09-07	Dsm Ip Assets Bv	Purificacion de anticuerpo de una unidad.
CA2812058C (en)	2010-09-20	2019-04-16	Bio-Rad Laboratories, Inc.	Dissociation of product-complexed contaminants in chromatography
WO2018081329A1 (en) *	2016-10-28	2018-05-03	Merck Sharp & Dohme Corp.	Purification process for removal of tyrosine sulfation antibody variants; purified compositions
JP7065105B2 (ja) *	2017-02-09	2022-05-11	ブラッコ・スイス・ソシエテ・アノニム	可溶性ｐｓｇｌ－１タンパク質変異体の精製のための方法
US11447547B1 (en)	2017-12-13	2022-09-20	Amgen Inc.	Method of antigen-binding protein production
US20230331773A1 (en) *	2022-04-15	2023-10-19	Pall Corporation	Chromatography device and method of use

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4723000A (en) *	1983-07-05	1988-02-02	Biospectrum, Inc.	Human interferon gamma and interleukin-2
US5115101A (en)	1988-06-08	1992-05-19	Miles Inc.	Removal of protein A from antibody preparations
US5464778A (en)	1989-03-08	1995-11-07	Board Of Regents Of The University Of Oklahoma	Glycoprotein ligand for P-selectin and methods of use thereof
US5378464A (en) *	1989-03-08	1995-01-03	Board Of Regents Of The University Of Oklahoma	Modulation of inflammatory responses by administration of GMP-140 or antibody to GMP-140
US5034133A (en) *	1990-07-26	1991-07-23	Schering-Corporation	Purification of human interleukin-4 from a CHO-cell line culture medium
US5530109A (en) *	1991-04-10	1996-06-25	Ludwig Institute For Cancer Research	DNA encoding glial mitogenic factors
DE69334350D1 (de) *	1992-10-23	2011-04-21	Genetics Inst Llc	P- Selectin Ligandenprotein
US5843707A (en) *	1992-10-23	1998-12-01	Genetics Institute, Inc.	Nucleic acid encoding a novel P-selectin ligand protein
US6277975B1 (en) *	1992-10-23	2001-08-21	Genetics Institute, Inc.	Fusions of P-selectin ligand protein and polynucleotides encoding same
US5429746A (en)	1994-02-22	1995-07-04	Smith Kline Beecham Corporation	Antibody purification
DE69522492T2 (de) *	1994-04-09	2002-05-23	F. Hoffmann-La Roche Ag, Basel	Verfahren zur Herstellung von Alpha-Interferon
US6008328A (en)	1994-10-13	1999-12-28	Amgen Inc.	Method for purifying keratinocyte growth factors
SE503424C2 (sv)	1994-11-14	1996-06-10	Pharmacia Ab	Process för rening av rekombinant koagulationsfaktor VIII
FR2737730B1 (fr)	1995-08-10	1997-09-05	Pasteur Merieux Serums Vacc	Procede de purification de virus par chromatographie
FR2738009B1 (fr)	1995-08-24	1997-10-31	Centre Nat Rech Scient	Procede d'obtention de polysaccharides sulfates
CA2268747A1 (en)	1996-11-15	1998-05-22	Genentech, Inc.	Purification of neurotrophins
WO1999019345A1 (en) *	1997-10-14	1999-04-22	Institute For Vaccine Development	Method for purifying retroviral particles and soluble viral antigens

2001
- 2001-03-27 CA CA2404155A patent/CA2404155C/en not_active Expired - Lifetime
- 2001-03-27 ES ES06006739T patent/ES2343023T3/es not_active Expired - Lifetime
- 2001-03-27 AU AU2001249515A patent/AU2001249515B2/en not_active Expired
- 2001-03-27 DK DK01922750T patent/DK1268514T3/da active
- 2001-03-27 NZ NZ521578A patent/NZ521578A/en unknown
- 2001-03-27 AT AT01922750T patent/ATE328895T1/de not_active IP Right Cessation
- 2001-03-27 JP JP2001571700A patent/JP5025874B2/ja not_active Expired - Lifetime
- 2001-03-27 AT AT06006739T patent/ATE461935T1/de not_active IP Right Cessation
- 2001-03-27 ES ES06006740T patent/ES2338687T3/es not_active Expired - Lifetime
- 2001-03-27 DE DE60140493T patent/DE60140493D1/de not_active Expired - Lifetime
- 2001-03-27 DK DK06006739.4T patent/DK1681298T3/da active
- 2001-03-27 AT AT06006740T patent/ATE448241T1/de not_active IP Right Cessation
- 2001-03-27 WO PCT/US2001/009815 patent/WO2001072769A2/en not_active Ceased
- 2001-03-27 EP EP06006740A patent/EP1681299B1/de not_active Expired - Lifetime
- 2001-03-27 US US09/819,157 patent/US6933370B2/en not_active Expired - Lifetime
- 2001-03-27 DE DE60141657T patent/DE60141657D1/de not_active Expired - Lifetime
- 2001-03-27 EP EP01922750A patent/EP1268514B1/de not_active Expired - Lifetime
- 2001-03-27 DE DE60120374T patent/DE60120374T2/de not_active Expired - Lifetime
- 2001-03-27 ES ES01922750T patent/ES2266188T3/es not_active Expired - Lifetime
- 2001-03-27 DK DK06006740.2T patent/DK1681299T3/da active
- 2001-03-27 AU AU4951501A patent/AU4951501A/xx active Pending
- 2001-03-27 EP EP06006739A patent/EP1681298B1/de not_active Expired - Lifetime
2012
- 2012-05-09 JP JP2012107204A patent/JP5596078B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ATE328895T1 (de)	2006-06-15
EP1681298A2 (de)	2006-07-19
EP1681298B1 (de)	2010-03-24
DK1681299T3 (da)	2010-02-01
US20020132991A1 (en)	2002-09-19
DE60140493D1 (de)	2009-12-24
EP1681299B1 (de)	2009-11-11
AU2001249515B2 (en)	2006-10-05
EP1681299A3 (de)	2006-12-27
US6933370B2 (en)	2005-08-23
JP2012184245A (ja)	2012-09-27
DE60120374T2 (de)	2007-06-06
ES2338687T3 (es)	2010-05-11
DK1681298T3 (da)	2010-06-14
WO2001072769A2 (en)	2001-10-04
ATE448241T1 (de)	2009-11-15
EP1681299A2 (de)	2006-07-19
ES2343023T3 (es)	2010-07-21
JP5596078B2 (ja)	2014-09-24
DK1268514T3 (da)	2006-10-09
EP1268514B1 (de)	2006-06-07
AU4951501A (en)	2001-10-08
WO2001072769A9 (en)	2003-04-03
JP2003528884A (ja)	2003-09-30
NZ521578A (en)	2004-08-27
DE60141657D1 (de)	2010-05-06
CA2404155C (en)	2011-08-09
EP1681298A3 (de)	2006-12-20
CA2404155A1 (en)	2001-10-04
EP1268514A2 (de)	2003-01-02
WO2001072769A3 (en)	2002-02-07
ES2266188T3 (es)	2007-03-01
JP5025874B2 (ja)	2012-09-12
DE60120374D1 (de)	2006-07-20

Legal Events

Date	Code	Title	Description
2010-09-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
ATE461935T1 (de)	2010-04-15	Verfahren zur reinigung von stark anionischen proteinen
DE60041119D1 (de)	2009-01-29	Verfahren zur präsentation von (poly)peptiden/proteinen auf bakteriophagenpartikeln via disulfidbindungen
EP1137941A4 (de)	2002-04-17	Proteingerüste für antikörper-nachahmer und andere bindende proteine
ATE392430T1 (de)	2008-05-15	Verfahren zur herstellung von dipeptiden
AU4185001A (en)	2001-09-12	Protein scaffolds for antibody mimics and other binding proteins
ATE353956T1 (de)	2007-03-15	Methoden zur virus-reinigung
ATE278785T1 (de)	2004-10-15	Neues verfahren zur gewinnung und reinigung von fusionsproteinen
DE69433934D1 (de)	2004-09-09	Verfahren und Zusammensetzungen zur erhöhten Proteinproduktion von rekombinanter DNA
DK0486515T3 (da)	1996-01-29	Fremgangsmåde til bestemmelse af den funktionelle aktivitet af frit protein S eller protein C i en plasmaprøve
ATE188994T1 (de)	2000-02-15	Methoden zur trans-destabilisierung von spezifischen proteinen in vivo
ATE374814T1 (de)	2007-10-15	Proteinsyntheseverfahren mit zellfreiem proteinsynthesesystem
ATE260972T1 (de)	2004-03-15	Verfahren zur aktivierung von denaturiertem protein
ATE223491T1 (de)	2002-09-15	Verfahren zur reinigung von biomolekül- oder proteinkomplexen
DE69021729D1 (de)	1995-09-21	Verfahren zur gewinnung von natürlich hergestelltem chymosin.
ATE250132T1 (de)	2003-10-15	Verfahren zur extraktion von periplasmatischen proteinen aus prokaryotischen mikroorganismen in der anwesenheit von arginin
DE3852105D1 (de)	1994-12-15	Verfahren zur herstellung von aprotinin und aprotinin-homologen in hefe.
DE69120409D1 (de)	1996-07-25	Verfahren zur reinigung von rekombinanten proteinen und dafür nützliche produkte
DE59004279D1 (de)	1994-03-03	Verfahren zur C-terminalen Modifizierung von Proteinen.
DE59404414D1 (de)	1997-11-27	Verfahren zur Abtrennung von L-Leucin und L-Isoleucin aus wässrigen Lösungen
ATA110696A (de)	1999-05-15	Verfahren zur gewinnung und reinigung von rekombinantem, nicht-lipidiertem osp-protein
ATE351909T1 (de)	2007-02-15	Neue peptidfragmente zur reinigung von proteinen
DE59007499D1 (de)	1994-11-24	Verfahren zur Enstaubung von Abgasen.
DE69721065D1 (de)	2003-05-22	Verfahren zur reiningung von 1,3,5-triisopropylbenzol
DE69832622D1 (de)	2006-01-05	Methoden zur durchforstung (screenen) von proteinen
ATA13789A (de)	1990-03-15	Verfahren zur abscheidung, insbesondere vorabscheidung von in industriellen abgasen bzw. industrieller abluft enthaltenen schadstoffen