DK1681299T3 - Fremgangsmåde til rensning af højt anioniske proteiner - Google Patents

Fremgangsmåde til rensning af højt anioniske proteiner

Info

Publication number
DK1681299T3
DK1681299T3 DK06006740.2T DK06006740T DK1681299T3 DK 1681299 T3 DK1681299 T3 DK 1681299T3 DK 06006740 T DK06006740 T DK 06006740T DK 1681299 T3 DK1681299 T3 DK 1681299T3
Authority
DK
Denmark
Prior art keywords
purification
proteins
highly anionic
sulfations
sulfated
Prior art date
Application number
DK06006740.2T
Other languages
English (en)
Inventor
Jonathan L Coffman
William Barry Foster
Bonnie J Germain
Shujun Sun
Jeffrey J Robinson
Original Assignee
Genetics Inst Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst Llc filed Critical Genetics Inst Llc
Application granted granted Critical
Publication of DK1681299T3 publication Critical patent/DK1681299T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
DK06006740.2T 2000-03-27 2001-03-27 Fremgangsmåde til rensning af højt anioniske proteiner DK1681299T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19335100P 2000-03-27 2000-03-27
EP01922750A EP1268514B1 (en) 2000-03-27 2001-03-27 Methods for purifying highly anionic proteins

Publications (1)

Publication Number Publication Date
DK1681299T3 true DK1681299T3 (da) 2010-02-01

Family

ID=22713294

Family Applications (3)

Application Number Title Priority Date Filing Date
DK06006739.4T DK1681298T3 (da) 2000-03-27 2001-03-27 Fremgangsmåder til oprensning af særdeles anioniske proteiner
DK06006740.2T DK1681299T3 (da) 2000-03-27 2001-03-27 Fremgangsmåde til rensning af højt anioniske proteiner
DK01922750T DK1268514T3 (da) 2000-03-27 2001-03-27 Fremgangsmåde til oprensning af særdeles anioniske proteiner

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK06006739.4T DK1681298T3 (da) 2000-03-27 2001-03-27 Fremgangsmåder til oprensning af særdeles anioniske proteiner

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK01922750T DK1268514T3 (da) 2000-03-27 2001-03-27 Fremgangsmåde til oprensning af særdeles anioniske proteiner

Country Status (11)

Country Link
US (1) US6933370B2 (da)
EP (3) EP1681299B1 (da)
JP (2) JP5025874B2 (da)
AT (3) ATE328895T1 (da)
AU (2) AU4951501A (da)
CA (1) CA2404155C (da)
DE (3) DE60120374T2 (da)
DK (3) DK1681298T3 (da)
ES (3) ES2266188T3 (da)
NZ (1) NZ521578A (da)
WO (1) WO2001072769A2 (da)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1404428B1 (en) * 2001-06-05 2006-07-19 Genetics Institute, LLC Methods for purifying highly anionic proteins
WO2003089450A2 (en) * 2002-04-22 2003-10-30 Recopharma Ab Fusion polypeptides and methods for inhibiting microbial adhesion
US7427659B2 (en) 2003-10-24 2008-09-23 Amgen Inc. Process for purifying proteins in a hydrophobic interaction chromatography flow-through fraction
RU2417093C2 (ru) * 2005-06-24 2011-04-27 Дезерт Лейк Текнолоджиз Очищенный компонент цианобактерий и способ применения
PT2253644E (pt) * 2005-12-20 2014-01-23 Bristol Myers Squibb Co Composições e métodos para a produção de uma composição
AR058568A1 (es) 2005-12-20 2008-02-13 Bristol Myers Squibb Co Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo
DK2089429T3 (da) * 2006-10-19 2015-01-12 Janssen Biotech Inc Fremgangsmåde til fremstilling af ikke-aggregerede antistof-fc-domæner
US20130116413A1 (en) * 2009-12-29 2013-05-09 Dr. Reddy's Laboratories, Inc. Purification of proteins
JP2013519652A (ja) * 2010-02-12 2013-05-30 ディーエスエム アイピー アセッツ ビー.ブイ. 単一ユニット抗体精製
EP2619217B1 (en) * 2010-09-20 2016-11-09 Bio-Rad Laboratories, Inc. Dissociation of product-complexed contaminants in chromatography
BR112019007856A8 (pt) 2016-10-28 2023-04-11 Merck Sharp & Dohme Composição, e, método para remover anticorpos de tirosina sulfatada ou fragmentos de ligação a antígeno dos mesmos
US12516102B1 (en) 2017-02-09 2026-01-06 Bracco Suisse Sa Process for the purification of soluble PSGL-1 protein variants
US11447547B1 (en) 2017-12-13 2022-09-20 Amgen Inc. Method of antigen-binding protein production
US20230331773A1 (en) * 2022-04-15 2023-10-19 Pall Corporation Chromatography device and method of use

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4723000A (en) * 1983-07-05 1988-02-02 Biospectrum, Inc. Human interferon gamma and interleukin-2
US5115101A (en) 1988-06-08 1992-05-19 Miles Inc. Removal of protein A from antibody preparations
US5378464A (en) * 1989-03-08 1995-01-03 Board Of Regents Of The University Of Oklahoma Modulation of inflammatory responses by administration of GMP-140 or antibody to GMP-140
US5464778A (en) * 1989-03-08 1995-11-07 Board Of Regents Of The University Of Oklahoma Glycoprotein ligand for P-selectin and methods of use thereof
US5034133A (en) * 1990-07-26 1991-07-23 Schering-Corporation Purification of human interleukin-4 from a CHO-cell line culture medium
US5530109A (en) * 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US6277975B1 (en) * 1992-10-23 2001-08-21 Genetics Institute, Inc. Fusions of P-selectin ligand protein and polynucleotides encoding same
AU677261B2 (en) * 1992-10-23 1997-04-17 Genetics Institute, Llc Novel P-selectin ligand protein
US5843707A (en) * 1992-10-23 1998-12-01 Genetics Institute, Inc. Nucleic acid encoding a novel P-selectin ligand protein
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
EP1104809A1 (en) 1994-04-09 2001-06-06 F. Hoffmann-La Roche Ag Process for producing alpha-interferon
US6008328A (en) 1994-10-13 1999-12-28 Amgen Inc. Method for purifying keratinocyte growth factors
SE503424C2 (sv) 1994-11-14 1996-06-10 Pharmacia Ab Process för rening av rekombinant koagulationsfaktor VIII
FR2737730B1 (fr) 1995-08-10 1997-09-05 Pasteur Merieux Serums Vacc Procede de purification de virus par chromatographie
FR2738009B1 (fr) 1995-08-24 1997-10-31 Centre Nat Rech Scient Procede d'obtention de polysaccharides sulfates
AU729459B2 (en) * 1996-11-15 2001-02-01 Genentech Inc. Purification of neurotrophins
AU9695698A (en) * 1997-10-14 1999-05-03 Avant Immunotherapeutics, Inc. Method for purifying retroviral particles and soluble viral antigens

Also Published As

Publication number Publication date
DE60141657D1 (de) 2010-05-06
CA2404155A1 (en) 2001-10-04
JP5025874B2 (ja) 2012-09-12
ES2266188T3 (es) 2007-03-01
EP1268514A2 (en) 2003-01-02
DE60120374T2 (de) 2007-06-06
EP1681298B1 (en) 2010-03-24
ATE461935T1 (de) 2010-04-15
JP5596078B2 (ja) 2014-09-24
JP2003528884A (ja) 2003-09-30
WO2001072769A3 (en) 2002-02-07
EP1681298A2 (en) 2006-07-19
EP1681299B1 (en) 2009-11-11
ATE328895T1 (de) 2006-06-15
NZ521578A (en) 2004-08-27
DK1268514T3 (da) 2006-10-09
EP1681299A2 (en) 2006-07-19
DK1681298T3 (da) 2010-06-14
WO2001072769A9 (en) 2003-04-03
US6933370B2 (en) 2005-08-23
AU4951501A (en) 2001-10-08
US20020132991A1 (en) 2002-09-19
EP1268514B1 (en) 2006-06-07
ATE448241T1 (de) 2009-11-15
EP1681298A3 (en) 2006-12-20
JP2012184245A (ja) 2012-09-27
AU2001249515B2 (en) 2006-10-05
WO2001072769A2 (en) 2001-10-04
CA2404155C (en) 2011-08-09
ES2343023T3 (es) 2010-07-21
EP1681299A3 (en) 2006-12-27
ES2338687T3 (es) 2010-05-11
DE60120374D1 (de) 2006-07-20
DE60140493D1 (de) 2009-12-24

Similar Documents

Publication Publication Date Title
DK1268514T3 (da) Fremgangsmåde til oprensning af særdeles anioniske proteiner
DK1144607T3 (da) Fremgangsmåde til præsentation af (poly)peptider/proteiner på bakteriofage partikler via disulfidbindinger
DK1084146T3 (da) Hybridprotein til inhibering af degranuleringen af mastocyter og anvendelse deraf
DE69739961D1 (de) Methoden zur Virus-Reinigung
DE69633563D1 (de) Neues verfahren zur gewinnung und reinigung von fusionsproteinen
DK1015622T3 (da) Praktisk sialylering in vitro af rekombinante glycoproteiner
ATE317441T1 (de) Cathepsin-02-protease
ES2166371T3 (es) Celulas de levadura tratadas para producir sustitutos de proteinas de sistemas de feromonas y usos de las mismas.
PT698216E (pt) Metodos de tipificacao do virus da hepatite c e reagentes para utilizar nestes
ATE449104T1 (de) Verfahren zur reinigung von fibrinogen
FI972384L (fi) Uudet dipeptidiset p-amidinobentsyyliamidit, jotka sisältävät N-terminaalisia sulfonyyli- tai amidinosulfonyyliryhmiä
ATE374814T1 (de) Proteinsyntheseverfahren mit zellfreiem proteinsynthesesystem
DE69032258D1 (de) Antikoagulierende Peptide
NO930428D0 (no) Proteinstrukturen til plantetoksingelonin
DK0816377T3 (da) Peptider, som binder sig til prothrombin og thrombin
ATE301712T1 (de) Z2-19a, ein menschliches homolog von dem protein 2-19
EA200400392A1 (ru) Связывающий каспазу-8 белок, его получение и применение
DK450187D0 (da) Fremgangsmaade til fremstilling af proteiner
PT633928E (pt) Microrganismos processo de preparacao e utilizacao
DE69632535D1 (de) Peptide zur detektion von hiv-1
WO2004007536A3 (en) Interactions of the epstein-barr virus protein ebna1, and uses thereof
DE59404414D1 (de) Verfahren zur Abtrennung von L-Leucin und L-Isoleucin aus wässrigen Lösungen
ES2191785T3 (es) Proteina de accion antitumoral.
WO1998038211A3 (en) Permuted hemoglobin-like proteins
SE9302856D0 (sv) Method and means for producing a plasmapeotein-binding protein