ATE472105T1 - Verfahren zur bestimmung eines analyts mit einer primären aminogruppe und kit zur etikettierung dieses analyts - Google Patents
Verfahren zur bestimmung eines analyts mit einer primären aminogruppe und kit zur etikettierung dieses analytsInfo
- Publication number
- ATE472105T1 ATE472105T1 AT08723906T AT08723906T ATE472105T1 AT E472105 T1 ATE472105 T1 AT E472105T1 AT 08723906 T AT08723906 T AT 08723906T AT 08723906 T AT08723906 T AT 08723906T AT E472105 T1 ATE472105 T1 AT E472105T1
- Authority
- AT
- Austria
- Prior art keywords
- analyte
- labeling
- dialdehyde
- charge
- amino group
- Prior art date
Links
- 239000012491 analyte Substances 0.000 title abstract 11
- 238000002372 labelling Methods 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 7
- -1 AMINO GROUP Chemical group 0.000 title 1
- ZNZYKNKBJPZETN-WELNAUFTSA-N Dialdehyde 11678 Chemical compound N1C2=CC=CC=C2C2=C1[C@H](C[C@H](/C(=C/O)C(=O)OC)[C@@H](C=C)C=O)NCC2 ZNZYKNKBJPZETN-WELNAUFTSA-N 0.000 abstract 7
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 238000004458 analytical method Methods 0.000 abstract 1
- 238000001294 liquid chromatography-tandem mass spectrometry Methods 0.000 abstract 1
- 125000005496 phosphonium group Chemical group 0.000 abstract 1
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
- G01N33/6806—Determination of free amino acids
- G01N33/6809—Determination of free amino acids involving fluorescent derivatizing reagents reacting non-specifically with all amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
- C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
- C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
- C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/11—Automated chemical analysis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/17—Nitrogen containing
- Y10T436/173845—Amine and quaternary ammonium
- Y10T436/174614—Tertiary amine
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Bioinformatics & Computational Biology (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP07104418 | 2007-03-19 | ||
| EP07123996 | 2007-12-21 | ||
| PCT/NL2008/050155 WO2008094043A2 (en) | 2007-03-19 | 2008-03-19 | Method for the determination of an analyte comprising a primary amino group, and kit for labeling said analyte |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE472105T1 true ATE472105T1 (de) | 2010-07-15 |
Family
ID=39315157
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT08723906T ATE472105T1 (de) | 2007-03-19 | 2008-03-19 | Verfahren zur bestimmung eines analyts mit einer primären aminogruppe und kit zur etikettierung dieses analyts |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US8323979B2 (de) |
| EP (1) | EP2122368B1 (de) |
| AT (1) | ATE472105T1 (de) |
| DE (1) | DE602008001609D1 (de) |
| WO (1) | WO2008094043A2 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3023420A1 (de) | 2014-11-18 | 2016-05-25 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Verfahren zur Bereitstellung stabiler Isoindolderivate |
| US11280802B2 (en) | 2016-05-26 | 2022-03-22 | Academisch Ziekenhuis Groningen | Methods and kits for the derivatization of a biogenic amine |
| JP6725144B2 (ja) * | 2016-09-06 | 2020-07-15 | 国立大学法人 和歌山大学 | アミノ酸分析法 |
| CN115667934A (zh) * | 2020-05-20 | 2023-01-31 | 豪夫迈·罗氏有限公司 | 质谱用试剂 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH508879A (fr) * | 1970-02-17 | 1971-06-15 | Roth Marc | Procédé de détermination de l'ammoniaque et de composés organiques aminés et ensemble de réactifs pour la mise en oeuvre de ce procédé |
| US3997298A (en) * | 1975-02-27 | 1976-12-14 | Cornell Research Foundation, Inc. | Liquid chromatography-mass spectrometry system and method |
| JPS6082967A (ja) * | 1983-10-14 | 1985-05-11 | Shimadzu Corp | アミノ酸分析方法及び装置 |
| DE3679441D1 (de) | 1985-03-04 | 1991-07-04 | Oread Lab Inc | Verfahren zur bestimmung von primaeraminen unter verwendung von aromatischen dialdehyden. |
| US4837166A (en) * | 1985-03-04 | 1989-06-06 | Oread Laboratories, Inc. | Assaying method for primary amines using aromatic dialdehydes |
| DE3676683D1 (de) * | 1986-02-26 | 1991-02-07 | Hewlett Packard Gmbh | Mischung von derivaten von aminosaeuren, verfahren zur herstellung der mischung und verwendung der mischung zur mengenbestimmung der aminosaeuren. |
| US4723022A (en) * | 1986-03-10 | 1988-02-02 | Oread Laboratories, Inc. | Substituted 2,3-naphthalenedicarboxaldehydes |
| GB9909245D0 (en) | 1999-04-22 | 1999-06-16 | Univ Cranfield | Reactive polymers and their application in reactions and assays |
| AU2002952747A0 (en) * | 2002-11-18 | 2002-12-05 | Ludwig Institute For Cancer Research | Method for analysing peptides |
| US7556969B2 (en) * | 2002-12-19 | 2009-07-07 | Northeastern University | Intensified neutral loss tags and use thereof in mass spectrometry |
| FR2890743B1 (fr) | 2005-09-09 | 2007-12-07 | Univ Toulouse | Methode de dosage des amines primaires a tres faible concentration |
-
2008
- 2008-03-19 US US12/531,975 patent/US8323979B2/en active Active
- 2008-03-19 WO PCT/NL2008/050155 patent/WO2008094043A2/en not_active Ceased
- 2008-03-19 DE DE602008001609T patent/DE602008001609D1/de active Active
- 2008-03-19 AT AT08723906T patent/ATE472105T1/de not_active IP Right Cessation
- 2008-03-19 EP EP08723906A patent/EP2122368B1/de active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2122368A2 (de) | 2009-11-25 |
| EP2122368B1 (de) | 2010-06-23 |
| WO2008094043A3 (en) | 2008-10-02 |
| DE602008001609D1 (de) | 2010-08-05 |
| US20100184231A1 (en) | 2010-07-22 |
| WO2008094043A2 (en) | 2008-08-07 |
| US8323979B2 (en) | 2012-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |