ATE472731T1 - Verfahren um die anwesenheit von krebs in einer probe zu bestimmen durch nachweis der expression eines ssx-2 gens und peptid davon - Google Patents

Verfahren um die anwesenheit von krebs in einer probe zu bestimmen durch nachweis der expression eines ssx-2 gens und peptid davon

Info

Publication number
ATE472731T1
ATE472731T1 AT99930755T AT99930755T ATE472731T1 AT E472731 T1 ATE472731 T1 AT E472731T1 AT 99930755 T AT99930755 T AT 99930755T AT 99930755 T AT99930755 T AT 99930755T AT E472731 T1 ATE472731 T1 AT E472731T1
Authority
AT
Austria
Prior art keywords
ssx
peptide
cancer
gene
expression
Prior art date
Application number
AT99930755T
Other languages
English (en)
Inventor
Ozlem Tureci
Ugur Sahin
Michael Pfreundschuh
Georg Rammensee
Stefan Stevanovic
Yao-Tseng Chen
Ali Gure
Lloyd Old
Original Assignee
Ludwig Inst For Cancer Res Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ludwig Inst For Cancer Res Ltd filed Critical Ludwig Inst For Cancer Res Ltd
Application granted granted Critical
Publication of ATE472731T1 publication Critical patent/ATE472731T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/82—Translation products from oncogenes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/82—Translation products from oncogenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Genetics & Genomics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT99930755T 1998-06-26 1999-06-25 Verfahren um die anwesenheit von krebs in einer probe zu bestimmen durch nachweis der expression eines ssx-2 gens und peptid davon ATE472731T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/105,839 US6287756B1 (en) 1997-05-05 1998-06-26 Methods for determining presence of cancer in a sample by determining expression of an SSX gene
PCT/US1999/014493 WO2000000824A1 (en) 1998-06-26 1999-06-25 Methods for determining presence of cancer in a sample by determining expression of an ssx gene, peptides derived from said ssx gene and ny-eso-1 gene, and uses thereof

Publications (1)

Publication Number Publication Date
ATE472731T1 true ATE472731T1 (de) 2010-07-15

Family

ID=22308065

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99930755T ATE472731T1 (de) 1998-06-26 1999-06-25 Verfahren um die anwesenheit von krebs in einer probe zu bestimmen durch nachweis der expression eines ssx-2 gens und peptid davon

Country Status (10)

Country Link
US (1) US6287756B1 (de)
EP (1) EP1090294B1 (de)
JP (1) JP3572316B2 (de)
KR (1) KR20010089128A (de)
CN (1) CN1315000A (de)
AT (1) ATE472731T1 (de)
AU (1) AU745777B2 (de)
CA (1) CA2334914C (de)
DE (1) DE69942544D1 (de)
WO (1) WO2000000824A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6800730B1 (en) * 1998-10-02 2004-10-05 Ludwig Institute For Cancer Research Isolated peptides which bind to MHC class II molecules, and uses thereof
WO2001055393A2 (en) 2000-01-28 2001-08-02 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Mhc class ii restricted t cell epitopes from the cancer antigen ny-eso-1
DK1276896T3 (da) * 2000-04-28 2010-10-18 Mannkind Corp Epitop-synkronisering i antigen-præsenterende celler
US7192921B2 (en) 2001-11-08 2007-03-20 The Burnham Institute Peptides that home to tumor lymphatic vasculature and methods of using same
EP1581790B1 (de) * 2001-11-08 2009-01-07 The Burnham Institute Peptide mit homing für lymphgefässtumor und ihre verwendung
US6896843B2 (en) 2002-08-30 2005-05-24 Kimberly-Clark Worldwide, Inc. Method of making a web which is extensible in at least one direction
AU2003270311A1 (en) * 2002-09-06 2004-03-29 Mannkind Corporation Epitope sequences
US7178491B2 (en) * 2003-06-05 2007-02-20 Caterpillar Inc Control system and method for engine valve actuator
AU2004249254B2 (en) * 2003-06-17 2010-07-08 Mannkind Corporation Combinations of tumor-associated antigens for the treatment of various types of cancers
ATE496129T1 (de) * 2003-07-22 2011-02-15 Ludwig Inst Cancer Res Von hla-klasse-ii-molekülen präsentierte ssx-2- peptide
JP2008526763A (ja) * 2004-12-29 2008-07-24 マンカインド コーポレイション 予防又は治療目的のｍｈｃクラスｉ拘束性エピトープに対する免疫応答の誘導、増強及び保持方法
EP1869106B1 (de) * 2005-03-28 2014-06-25 Dendritic Nanotechnologies, Inc. Janus-dendrimere und -dendrone
SG162817A1 (en) 2005-06-17 2010-07-29 Mannkind Corp Methods and compositions.to elicit multivalent immune responses against dominant and subdominant epitopes, expressed on cancer cells and tumor stroma
WO2008103645A2 (en) * 2007-02-19 2008-08-28 Wisconsin Alumni Research Foundation Prostate cancer and melanoma antigens
WO2011130742A2 (en) 2010-04-16 2011-10-20 Wisconsin Alumni Research Foundation Diagnostic evaluation of antibody responses to commonly recognized prostate cancer-associated antigens
CN102251035B (zh) * 2011-07-05 2013-01-23 北京大学人民医院 基于ssx-2基因辅助诊断多发性骨髓瘤患者的定量检测试剂盒
CN104004822B (zh) * 2013-02-27 2018-08-07 霍克克 Ssx2ip在预测或诊断肿瘤转移中的应用
WO2016054079A1 (en) 2014-09-29 2016-04-07 Zyomed Corp. Systems and methods for blood glucose and other analyte detection and measurement using collision computing
US9554738B1 (en) 2016-03-30 2017-01-31 Zyomed Corp. Spectroscopic tomography systems and methods for noninvasive detection and measurement of analytes using collision computing
CN110950949B (zh) * 2018-09-26 2022-04-05 香雪生命科学技术（广东）有限公司 一种识别ssx2抗原的t细胞受体
CN110218774A (zh) * 2019-06-27 2019-09-10 杭州艾迪康医学检验中心有限公司 用于检测syt-ssx融合基因的引物、试剂盒和方法
WO2024233388A2 (en) * 2023-05-05 2024-11-14 Memorial Sloan-Kettering Cancer Center Sarcoma cancer vaccines and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5804381A (en) 1996-10-03 1998-09-08 Cornell Research Foundation Isolated nucleic acid molecule encoding an esophageal cancer associated antigen, the antigen itself, and uses thereof
BR9406652A (pt) * 1993-03-05 1996-09-10 Cytel Corp Composição
GB9414580D0 (en) * 1994-07-19 1994-09-07 Cancer Res Campaign Tech Materials and methods relating to the diagnosis of synovial sarcomas
US5840568A (en) * 1995-06-07 1998-11-24 Ludwig Institute For Cancer Research Hodgkin's disease associated molecules and uses thereof
US5698396A (en) * 1995-06-07 1997-12-16 Ludwig Institute For Cancer Research Method for identifying auto-immunoreactive substances from a subject
US6025191A (en) 1995-06-07 2000-02-15 Ludwig Institute For Cancer Research Isolated nucleic acid molecules which encode a melanoma specific antigen and uses thereof
US6291658B1 (en) * 1997-05-05 2001-09-18 Ludwig Institute For Cancer Research Isolated nucleic acid molecules encoding SSX family members and thereof
US5888751A (en) * 1997-07-15 1999-03-30 Ludwig Institute For Cancer Research Method for diagnosis and treating cancers, and methods for identifying pathogenic markers in a sample of normal cells

Also Published As

Publication number Publication date
US6287756B1 (en) 2001-09-11
CA2334914C (en) 2010-10-19
EP1090294A4 (de) 2003-02-26
CN1315000A (zh) 2001-09-26
DE69942544D1 (de) 2010-08-12
EP1090294B1 (de) 2010-06-30
CA2334914A1 (en) 2000-01-06
JP3572316B2 (ja) 2004-09-29
JP2002519013A (ja) 2002-07-02
WO2000000824A1 (en) 2000-01-06
AU745777B2 (en) 2002-03-28
AU4722199A (en) 2000-01-17
KR20010089128A (ko) 2001-09-29
EP1090294A1 (de) 2001-04-11

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