ATE491021T1 - Verfahren zur produktion eines zytotoxischen lymphozyten - Google Patents

Verfahren zur produktion eines zytotoxischen lymphozyten

Info

Publication number
ATE491021T1
ATE491021T1 AT03712887T AT03712887T ATE491021T1 AT E491021 T1 ATE491021 T1 AT E491021T1 AT 03712887 T AT03712887 T AT 03712887T AT 03712887 T AT03712887 T AT 03712887T AT E491021 T1 ATE491021 T1 AT E491021T1
Authority
AT
Austria
Prior art keywords
cytotoxic lymphocyte
producing
cytotoxic
lymphocyte
fibronectin
Prior art date
Application number
AT03712887T
Other languages
English (en)
Inventor
Hiroaki Sagawa
Mitsuko Ideno
Ikunoshin Kato
Original Assignee
Takara Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Bio Inc filed Critical Takara Bio Inc
Application granted granted Critical
Publication of ATE491021T1 publication Critical patent/ATE491021T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/15—Natural-killer [NK] cells; Natural-killer T [NKT] cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/41—Vertebrate antigens
    • A61K40/42—Cancer antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/46—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C12N2501/58—Adhesion molecules, e.g. ICAM, VCAM, CD18 (ligand), CD11 (ligand), CD49 (ligand)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/50—Proteins
    • C12N2533/52—Fibronectin; Laminin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT03712887T 2002-03-25 2003-03-25 Verfahren zur produktion eines zytotoxischen lymphozyten ATE491021T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2002084414 2002-03-25
PCT/JP2003/003575 WO2003080817A1 (fr) 2002-03-25 2003-03-25 Procede de production de lymphocyte cytotoxique

Publications (1)

Publication Number Publication Date
ATE491021T1 true ATE491021T1 (de) 2010-12-15

Family

ID=28449211

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03712887T ATE491021T1 (de) 2002-03-25 2003-03-25 Verfahren zur produktion eines zytotoxischen lymphozyten

Country Status (14)

Country Link
US (3) US8728811B2 (de)
EP (3) EP2305793B1 (de)
JP (1) JP4406566B2 (de)
KR (2) KR100786054B1 (de)
CN (3) CN101735981B (de)
AT (1) ATE491021T1 (de)
AU (2) AU2003221073B2 (de)
CA (1) CA2479288C (de)
DE (1) DE60335253D1 (de)
EA (1) EA010434B1 (de)
ES (3) ES2397319T3 (de)
MX (1) MXPA04009287A (de)
TW (2) TWI334442B (de)
WO (1) WO2003080817A1 (de)

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RU2634862C2 (ru) 2011-05-19 2017-11-07 Торэй Индастриз, Инк. Агент, индуцирующий иммунитет
EP4261277A3 (de) 2016-04-08 2024-01-03 Emory University Verfahren zur behandlung von krebs und infektionskrankheiten mit zellbasierten therapien
KR20190033568A (ko) 2016-07-29 2019-03-29 다카라 바이오 가부시키가이샤 줄기세포의 제조에 사용되는 피브로넥틴 프래그먼트
WO2018135646A1 (ja) 2017-01-20 2018-07-26 国立大学法人京都大学 ＣＤ８α＋β＋細胞傷害性Ｔ細胞の製造方法
KR20200112868A (ko) * 2018-01-25 2020-10-05 다카라 바이오 가부시키가이샤 림프구의 제조방법
US12467034B2 (en) 2018-02-14 2025-11-11 Sunnybrook Research Institute Method for generating cells of the T cell lineage
WO2021200901A1 (ja) 2020-03-31 2021-10-07 国立大学法人京都大学 Ｔ前駆細胞の製造方法
JPWO2024248141A1 (de) 2023-06-02 2024-12-05

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Also Published As

Publication number Publication date
CA2479288A1 (en) 2003-10-02
WO2003080817A1 (fr) 2003-10-02
CA2479288C (en) 2015-02-24
CN100591760C (zh) 2010-02-24
TW200400265A (en) 2004-01-01
TWI334442B (en) 2010-12-11
EP1496109A4 (de) 2006-07-19
JP4406566B2 (ja) 2010-01-27
EP1496109B1 (de) 2010-12-08
CN101735981A (zh) 2010-06-16
US8975070B2 (en) 2015-03-10
EP2305793B1 (de) 2012-10-17
CN102321579A (zh) 2012-01-18
CN1656215A (zh) 2005-08-17
AU2008243221B2 (en) 2011-10-27
TW201043699A (en) 2010-12-16
EP1496109A1 (de) 2005-01-12
EP2305796B1 (de) 2012-10-24
DE60335253D1 (de) 2011-01-20
AU2008243221A1 (en) 2008-12-04
ES2397319T3 (es) 2013-03-06
HK1079543A1 (zh) 2006-04-07
US8728811B2 (en) 2014-05-20
AU2003221073B2 (en) 2008-08-21
US20050227354A1 (en) 2005-10-13
HK1144105A1 (en) 2011-01-28
CN101735981B (zh) 2013-01-02
EA010434B1 (ru) 2008-08-29
AU2003221073A1 (en) 2003-10-08
KR100786054B1 (ko) 2007-12-17
JPWO2003080817A1 (ja) 2005-07-28
MXPA04009287A (es) 2005-01-25
EP2305793A1 (de) 2011-04-06
KR20070015620A (ko) 2007-02-05
US20140212972A1 (en) 2014-07-31
KR100895231B1 (ko) 2009-05-04
ES2396447T3 (es) 2013-02-21
EA200401242A1 (ru) 2005-04-28
EP2305796A1 (de) 2011-04-06
KR20040099352A (ko) 2004-11-26
ES2356814T3 (es) 2011-04-13
US20080227204A1 (en) 2008-09-18

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