ATE510838T1 - Verfahren zur herstellung von 2-methyl-1-(2- methylpropyl)-1h-imidazoä4,5-cüä1,5ünaphthyridi - 4-amin - Google Patents
Verfahren zur herstellung von 2-methyl-1-(2- methylpropyl)-1h-imidazoä4,5-cüä1,5ünaphthyridi - 4-aminInfo
- Publication number
- ATE510838T1 ATE510838T1 AT05855868T AT05855868T ATE510838T1 AT E510838 T1 ATE510838 T1 AT E510838T1 AT 05855868 T AT05855868 T AT 05855868T AT 05855868 T AT05855868 T AT 05855868T AT E510838 T1 ATE510838 T1 AT E510838T1
- Authority
- AT
- Austria
- Prior art keywords
- methylpropyl
- amine
- methyl
- imidazoä4
- cuä1
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- ZXBCLVSLRUWISJ-UHFFFAOYSA-N 2-methyl-1-(2-methylpropyl)imidazo[4,5-c][1,5]naphthyridin-4-amine Chemical compound C1=CC=NC2=C3N(CC(C)C)C(C)=NC3=C(N)N=C21 ZXBCLVSLRUWISJ-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US64112904P | 2004-12-30 | 2004-12-30 | |
| US70867905P | 2005-08-16 | 2005-08-16 | |
| PCT/US2005/047375 WO2006074046A2 (en) | 2004-12-30 | 2005-12-28 | Process for preparing 2-methyl-1-(2-methylpropyl)-1h-imidazo[4,5-c][1,5]naphthyridin-4-amine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE510838T1 true ATE510838T1 (de) | 2011-06-15 |
Family
ID=36615477
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05855868T ATE510838T1 (de) | 2004-12-30 | 2005-12-28 | Verfahren zur herstellung von 2-methyl-1-(2- methylpropyl)-1h-imidazoä4,5-cüä1,5ünaphthyridi - 4-amin |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US8436176B2 (de) |
| EP (2) | EP1833827B9 (de) |
| JP (2) | JP2008526758A (de) |
| AT (1) | ATE510838T1 (de) |
| AU (1) | AU2005322844A1 (de) |
| BR (1) | BRPI0519797A (de) |
| CA (2) | CA2592898A1 (de) |
| CR (1) | CR9217A (de) |
| DK (1) | DK1833827T3 (de) |
| IL (1) | IL184310A (de) |
| MX (1) | MX2007008131A (de) |
| NO (1) | NO339859B1 (de) |
| PL (1) | PL1833827T3 (de) |
| PT (1) | PT1833827E (de) |
| RU (1) | RU2388760C2 (de) |
| WO (2) | WO2006071862A2 (de) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040265351A1 (en) | 2003-04-10 | 2004-12-30 | Miller Richard L. | Methods and compositions for enhancing immune response |
| NZ545412A (en) | 2003-08-27 | 2008-12-24 | Coley Pharm Group Inc | Aryloxy and arylalkyleneoxy substituted imidazoquinolines |
| KR101494056B1 (ko) | 2003-10-03 | 2015-02-16 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 피라졸로피리딘 및 그의 유사체 |
| EP1673087B1 (de) | 2003-10-03 | 2015-05-13 | 3M Innovative Properties Company | Alkoxy-substituierte imidazochinoline |
| CN1894251B (zh) * | 2003-11-17 | 2011-06-29 | 默克和西伊公司 | (6r)-l-赤型-四氢生物蝶呤二盐酸盐的晶型 |
| AU2004293078B2 (en) | 2003-11-25 | 2012-01-19 | 3M Innovative Properties Company | Substituted imidazo ring systems and methods |
| CN1960992B (zh) * | 2004-06-02 | 2011-10-19 | 桑多斯股份公司 | 晶体形式的美罗培南中间体 |
| US8541438B2 (en) | 2004-06-18 | 2013-09-24 | 3M Innovative Properties Company | Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines |
| JP5209312B2 (ja) | 2004-09-02 | 2013-06-12 | スリーエム イノベイティブ プロパティズ カンパニー | １−アルコキシ１ｈ−イミダゾ環系および方法 |
| US8080560B2 (en) | 2004-12-17 | 2011-12-20 | 3M Innovative Properties Company | Immune response modifier formulations containing oleic acid and methods |
| CA2592904C (en) | 2004-12-30 | 2015-04-07 | 3M Innovative Properties Company | Chiral fused [1,2]imidazo[4,5-c] ring compounds |
| JP5313502B2 (ja) | 2004-12-30 | 2013-10-09 | スリーエム イノベイティブ プロパティズ カンパニー | 置換キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物 |
| CA2602083A1 (en) | 2005-02-09 | 2006-08-09 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted thiazolo(4,5-c) ring compounds and methods |
| US20080318998A1 (en) | 2005-02-09 | 2008-12-25 | Coley Pharmaceutical Group, Inc. | Alkyloxy Substituted Thiazoloquinolines and Thiazolonaphthyridines |
| CA2597446A1 (en) | 2005-02-11 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Substituted imidazoquinolines and imidazonaphthyridines |
| AU2006223634A1 (en) | 2005-02-23 | 2006-09-21 | Coley Pharmaceutical Group, Inc. | Hydroxyalkyl substituted imidazoquinolines |
| AU2006216686A1 (en) | 2005-02-23 | 2006-08-31 | Coley Pharmaceutical Group, Inc. | Method of preferentially inducing the biosynthesis of interferon |
| EP1851218A2 (de) | 2005-02-23 | 2007-11-07 | 3M Innovative Properties Company | Hydroxyalkylsubstituierte imidazochinolinverbindungen und verfahren |
| AU2006287270A1 (en) | 2005-09-09 | 2007-03-15 | Coley Pharmaceutical Group, Inc. | Amide and carbamate derivatives of N-{2-[4-amino-2- (ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-1,1-dimethylethyl}methanesulfonamide and methods |
| ZA200803029B (en) | 2005-09-09 | 2009-02-25 | Coley Pharm Group Inc | Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods |
| JP5305909B2 (ja) * | 2005-09-21 | 2013-10-02 | フォーエスシー アクチエンゲゼルシャフト | ヒストンデアセチラーゼインヒビターとしてのスルホニルピロール塩酸塩 |
| NZ567357A (en) * | 2005-10-31 | 2011-05-27 | Janssen Pharmaceutica Nv | Novel processes for the preparation of piperazinyl and diazapanyl benzamide derivatives |
| WO2007056112A2 (en) | 2005-11-04 | 2007-05-18 | Coley Pharmaceutical Group, Inc. | Hydroxy and alkoxy substituted 1h-imidazoquinolines and methods |
| EP1988896A4 (de) | 2006-02-22 | 2011-07-27 | 3M Innovative Properties Co | Konjugate zur modifizierung von immunreaktionen |
| WO2007106854A2 (en) | 2006-03-15 | 2007-09-20 | Coley Pharmaceutical Group, Inc. | Hydroxy and alkoxy substituted 1h-imidazonaphthyridines and methods |
| JP5318757B2 (ja) * | 2006-06-16 | 2013-10-16 | ハー・ルンドベック・アクチエゼルスカベット | 神経因性疼痛の治療のための、組み合わされたセロトニンおよびノルエピネフリン再取り込み阻害を有する４−［２−（４−メチルフェニルスルファニル）−フェニル］ピペリジンの結晶形 |
| WO2008016475A2 (en) | 2006-07-31 | 2008-02-07 | 3M Innovative Properties Company | Immune response modifier compositions and methods |
| US8178539B2 (en) | 2006-09-06 | 2012-05-15 | 3M Innovative Properties Company | Substituted 3,4,6,7-tetrahydro-5H-1,2a,4a,8-tetraazacyclopenta[cd]phenalenes and methods |
| CN101568544B (zh) * | 2006-10-27 | 2016-10-26 | 西格诺药品有限公司 | 包含4‑[9‑(四氢‑呋喃‑3‑基)‑8‑(2,4,6‑三氟‑苯氨基)‑9h‑嘌呤‑2‑基氨基]‑环己烷‑1‑醇的固体形式，其组合物，及其用途 |
| US20080149123A1 (en) | 2006-12-22 | 2008-06-26 | Mckay William D | Particulate material dispensing hairbrush with combination bristles |
| EP2085397A1 (de) * | 2008-01-21 | 2009-08-05 | Esteve Quimica, S.A. | Kristalline Form von Abacavir |
| US7935817B2 (en) * | 2008-03-31 | 2011-05-03 | Apotex Pharmachem Inc. | Salt form and cocrystals of adefovir dipivoxil and processes for preparation thereof |
| AR071318A1 (es) * | 2008-04-15 | 2010-06-09 | Basilea Pharmaceutica Ag | Benzhidril ester del acido (6r,7r)-7-{2-(5-amino-[1,2,4]tiadiazol-3-il)-2-[(z)-tritiloxiimino]-acetilamino}-3-[(r)-1'-terc-butoxicarbonil-2-oxo-[1,3']bipirrolidinil-(3e)-ilidenometil]-8-oxo-5-tia-1-aza-biciclo[4.2.0]oct-2-eno-2-carboxilico cristalino; su elaboracion y uso |
| US8097719B2 (en) * | 2008-07-15 | 2012-01-17 | Genesen Labs | Meropenem intermediate in novel crystalline form and a method of manufacture of meropenem |
| NZ601967A (en) | 2010-03-12 | 2015-03-27 | Omeros Corp | Pde10 inhibitors and related compositions and methods |
| LT2606047T (lt) | 2010-08-17 | 2017-04-10 | 3M Innovative Properties Company | Imuninio atsako modifikatoriaus junginio lipidizuotos kompozicijos, sudėtys ir būdai |
| SG188361A1 (en) * | 2010-09-01 | 2013-04-30 | Arena Pharm Inc | Non-hygroscopic salts of 5-ht2c agonists |
| CA2838023C (en) | 2011-06-03 | 2019-08-13 | 3M Innovative Properties Company | Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom |
| EP2717919B1 (de) | 2011-06-03 | 2016-08-03 | 3M Innovative Properties Company | Heterobifunktionale linker mit polyethylenglykolsegmenten und daraus hergestellte immunantwort-modifizierende konjugate |
| WO2013007768A1 (en) | 2011-07-13 | 2013-01-17 | F. Hoffmann-La Roche Ag | Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors |
| US9174973B2 (en) * | 2011-09-30 | 2015-11-03 | Sunshine Lake Pharma Co., Ltd. | Crystalline forms of azilsartan and preparation and uses thereof |
| WO2013165898A2 (en) * | 2012-05-01 | 2013-11-07 | The Trustees Of The University Of Pennsylvania | Compositions and methods for inhibiting resolvases |
| NZ716462A (en) | 2014-04-28 | 2017-11-24 | Omeros Corp | Optically active pde10 inhibitor |
| NZ716494A (en) | 2014-04-28 | 2017-07-28 | Omeros Corp | Processes and intermediates for the preparation of a pde10 inhibitor |
| CN107530313A (zh) | 2015-04-24 | 2018-01-02 | 奥默罗斯公司 | Pde10抑制剂以及相关组合物和方法 |
| WO2017079678A1 (en) | 2015-11-04 | 2017-05-11 | Omeros Corporation | Solid state forms of a pde10 inhibitor |
| EP3728255B1 (de) | 2017-12-20 | 2022-01-26 | 3M Innovative Properties Company | Amid-substituierte imidazo[4,5-c]chinolin-verbindungen mit verzweigtkettenverbindungsgruppe zur verwendung als immunreaktionsmodifikator |
| EP3870292A4 (de) | 2018-10-26 | 2022-11-09 | The Research Foundation for The State University of New York | Kombination von serotonin-spezifischem wiederaufnahmeinhibitor und serotonin-1a-rezeptor-partialagonist zur verminderung von l-dopa-induzierter dyskinesie |
| CN111303230B (zh) * | 2020-03-09 | 2021-07-13 | 中国食品药品检定研究院 | 一种黄体酮共晶物及其制备方法和用途 |
Family Cites Families (96)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3314941A (en) * | 1964-06-23 | 1967-04-18 | American Cyanamid Co | Novel substituted pyridodiazepins |
| US3764681A (en) * | 1970-07-08 | 1973-10-09 | Lilly Co Eli | Certain tetrazolo-(1,5-a) quinoline compounds as fungus control agents |
| US3917624A (en) * | 1972-09-27 | 1975-11-04 | Pfizer | Process for producing 2-amino-nicotinonitrile intermediates |
| ZA848968B (en) * | 1983-11-18 | 1986-06-25 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinolines and 1h-imidazo(4,5-c)quinolin-4-amines |
| IL73534A (en) * | 1983-11-18 | 1990-12-23 | Riker Laboratories Inc | 1h-imidazo(4,5-c)quinoline-4-amines,their preparation and pharmaceutical compositions containing certain such compounds |
| US5238944A (en) * | 1988-12-15 | 1993-08-24 | Riker Laboratories, Inc. | Topical formulations and transdermal delivery systems containing 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine |
| US5756747A (en) * | 1989-02-27 | 1998-05-26 | Riker Laboratories, Inc. | 1H-imidazo 4,5-c!quinolin-4-amines |
| US5037986A (en) * | 1989-03-23 | 1991-08-06 | Minnesota Mining And Manufacturing Company | Olefinic 1H-imidazo[4,5-c]quinolin-4-amines |
| US4929624A (en) * | 1989-03-23 | 1990-05-29 | Minnesota Mining And Manufacturing Company | Olefinic 1H-imidazo(4,5-c)quinolin-4-amines |
| NZ232740A (en) | 1989-04-20 | 1992-06-25 | Riker Laboratories Inc | Solution for parenteral administration comprising a 1h-imidazo(4,5-c) quinolin-4-amine derivative, an acid and a tonicity adjuster |
| US4988815A (en) * | 1989-10-26 | 1991-01-29 | Riker Laboratories, Inc. | 3-Amino or 3-nitro quinoline compounds which are intermediates in preparing 1H-imidazo[4,5-c]quinolines |
| RO108347B1 (ro) * | 1989-10-30 | 1994-04-28 | Bellon Labor Sa Roger | DERIVATI DE BENZO-(b)-NAFTIRIDIN-1,8 SI PROCEDEU DE PREPARARE A ACESTORA |
| CA2093132C (en) * | 1990-10-05 | 2002-02-26 | John F. Gerster | Process for the preparation of imidazo[4,5-c]quinolin-4-amines |
| US5389640A (en) * | 1991-03-01 | 1995-02-14 | Minnesota Mining And Manufacturing Company | 1-substituted, 2-substituted 1H-imidazo[4,5-c]quinolin-4-amines |
| US5175296A (en) * | 1991-03-01 | 1992-12-29 | Minnesota Mining And Manufacturing Company | Imidazo[4,5-c]quinolin-4-amines and processes for their preparation |
| US5268376A (en) * | 1991-09-04 | 1993-12-07 | Minnesota Mining And Manufacturing Company | 1-substituted 1H-imidazo[4,5-c]quinolin-4-amines |
| US5266575A (en) * | 1991-11-06 | 1993-11-30 | Minnesota Mining And Manufacturing Company | 2-ethyl 1H-imidazo[4,5-ciquinolin-4-amines |
| IL105325A (en) * | 1992-04-16 | 1996-11-14 | Minnesota Mining & Mfg | Immunogen/vaccine adjuvant composition |
| US5395937A (en) * | 1993-01-29 | 1995-03-07 | Minnesota Mining And Manufacturing Company | Process for preparing quinoline amines |
| KR100341341B1 (ko) * | 1993-07-15 | 2002-11-25 | 미네소타 마이닝 앤드 매뉴팩춰링 캄파니 | 이미다조[4,5-c]피리딘-4-아민 |
| US5352784A (en) * | 1993-07-15 | 1994-10-04 | Minnesota Mining And Manufacturing Company | Fused cycloalkylimidazopyridines |
| US5482936A (en) * | 1995-01-12 | 1996-01-09 | Minnesota Mining And Manufacturing Company | Imidazo[4,5-C]quinoline amines |
| JPH09208584A (ja) | 1996-01-29 | 1997-08-12 | Terumo Corp | アミド誘導体、およびそれを含有する医薬製剤、および合成中間体 |
| JPH09255926A (ja) | 1996-03-26 | 1997-09-30 | Diatex Co Ltd | 粘着テープ |
| US5741908A (en) * | 1996-06-21 | 1998-04-21 | Minnesota Mining And Manufacturing Company | Process for reparing imidazoquinolinamines |
| US5693811A (en) * | 1996-06-21 | 1997-12-02 | Minnesota Mining And Manufacturing Company | Process for preparing tetrahdroimidazoquinolinamines |
| HUP9904665A3 (en) * | 1996-10-25 | 2000-11-28 | Minnesota Mining And Mfg Co Sa | Immune response modifier compounds for treatment of th2 mediated and related diseases |
| ATE224878T1 (de) * | 1996-11-04 | 2002-10-15 | Aventis Cropscience Sa | 1-polyarylpyrazole als pestizide |
| US5939090A (en) * | 1996-12-03 | 1999-08-17 | 3M Innovative Properties Company | Gel formulations for topical drug delivery |
| JP4101302B2 (ja) * | 1997-01-09 | 2008-06-18 | テルモ株式会社 | 新規アミド誘導体および合成中間体 |
| UA67760C2 (uk) * | 1997-12-11 | 2004-07-15 | Міннесота Майнінг Енд Мануфакчурінг Компані | Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки |
| JPH11222432A (ja) | 1998-02-03 | 1999-08-17 | Terumo Corp | インターフェロンを誘起するアミド誘導体を含有する外用剤 |
| US6110929A (en) * | 1998-07-28 | 2000-08-29 | 3M Innovative Properties Company | Oxazolo, thiazolo and selenazolo [4,5-c]-quinolin-4-amines and analogs thereof |
| JP2000119271A (ja) | 1998-08-12 | 2000-04-25 | Hokuriku Seiyaku Co Ltd | １ｈ―イミダゾピリジン誘導体 |
| US6518280B2 (en) * | 1998-12-11 | 2003-02-11 | 3M Innovative Properties Company | Imidazonaphthyridines |
| NZ512628A (en) * | 1999-01-08 | 2004-03-26 | 3M Innovative Properties Co | Formulations and methods for treatment of mucosal associated conditions with an immune response modifier |
| US20020058674A1 (en) * | 1999-01-08 | 2002-05-16 | Hedenstrom John C. | Systems and methods for treating a mucosal surface |
| US6558951B1 (en) * | 1999-02-11 | 2003-05-06 | 3M Innovative Properties Company | Maturation of dendritic cells with immune response modifying compounds |
| JP2000247884A (ja) | 1999-03-01 | 2000-09-12 | Sumitomo Pharmaceut Co Ltd | アラキドン酸誘発皮膚疾患治療剤 |
| US6451810B1 (en) * | 1999-06-10 | 2002-09-17 | 3M Innovative Properties Company | Amide substituted imidazoquinolines |
| US6541485B1 (en) * | 1999-06-10 | 2003-04-01 | 3M Innovative Properties Company | Urea substituted imidazoquinolines |
| US6331539B1 (en) * | 1999-06-10 | 2001-12-18 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
| US6573273B1 (en) * | 1999-06-10 | 2003-06-03 | 3M Innovative Properties Company | Urea substituted imidazoquinolines |
| US6756382B2 (en) * | 1999-06-10 | 2004-06-29 | 3M Innovative Properties Company | Amide substituted imidazoquinolines |
| US6376669B1 (en) * | 1999-11-05 | 2002-04-23 | 3M Innovative Properties Company | Dye labeled imidazoquinoline compounds |
| US6894060B2 (en) * | 2000-03-30 | 2005-05-17 | 3M Innovative Properties Company | Method for the treatment of dermal lesions caused by envenomation |
| US20020055517A1 (en) * | 2000-09-15 | 2002-05-09 | 3M Innovative Properties Company | Methods for delaying recurrence of herpes virus symptoms |
| EP1360486A2 (de) * | 2000-12-08 | 2003-11-12 | 3M Innovative Properties Company | Screeningverfahren zur identifizierung von selektiven interferon-alpha-induzierenden verbindungen |
| US6677348B2 (en) * | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Aryl ether substituted imidazoquinolines |
| US6660735B2 (en) * | 2000-12-08 | 2003-12-09 | 3M Innovative Properties Company | Urea substituted imidazoquinoline ethers |
| UA74852C2 (en) * | 2000-12-08 | 2006-02-15 | 3M Innovative Properties Co | Urea-substituted imidazoquinoline ethers |
| US6677347B2 (en) * | 2000-12-08 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamido ether substituted imidazoquinolines |
| US6545017B1 (en) * | 2000-12-08 | 2003-04-08 | 3M Innovative Properties Company | Urea substituted imidazopyridines |
| US6664264B2 (en) * | 2000-12-08 | 2003-12-16 | 3M Innovative Properties Company | Thioether substituted imidazoquinolines |
| US6660747B2 (en) * | 2000-12-08 | 2003-12-09 | 3M Innovative Properties Company | Amido ether substituted imidazoquinolines |
| US6667312B2 (en) * | 2000-12-08 | 2003-12-23 | 3M Innovative Properties Company | Thioether substituted imidazoquinolines |
| US20020107262A1 (en) * | 2000-12-08 | 2002-08-08 | 3M Innovative Properties Company | Substituted imidazopyridines |
| US6664265B2 (en) * | 2000-12-08 | 2003-12-16 | 3M Innovative Properties Company | Amido ether substituted imidazoquinolines |
| US6664260B2 (en) * | 2000-12-08 | 2003-12-16 | 3M Innovative Properties Company | Heterocyclic ether substituted imidazoquinolines |
| US6545016B1 (en) * | 2000-12-08 | 2003-04-08 | 3M Innovative Properties Company | Amide substituted imidazopyridines |
| US6525064B1 (en) * | 2000-12-08 | 2003-02-25 | 3M Innovative Properties Company | Sulfonamido substituted imidazopyridines |
| US7226928B2 (en) * | 2001-06-15 | 2007-06-05 | 3M Innovative Properties Company | Methods for the treatment of periodontal disease |
| CA2458876A1 (en) * | 2001-08-30 | 2003-03-13 | 3M Innovative Properties Company | Methods of maturing plasmacytoid dendritic cells using immune response modifier molecules |
| ES2367422T3 (es) * | 2001-10-09 | 2011-11-03 | Amgen Inc. | Derivados de imidazol como agentes antiinflamatorios. |
| EP1478371A4 (de) * | 2001-10-12 | 2007-11-07 | Univ Iowa Res Found | Verfahren und produkte zur verbesserung der immunantworten mit imidazochinolin-verbindungen |
| DE60230340D1 (de) * | 2001-11-16 | 2009-01-22 | 3M Innovative Properties Co | N-Ä4-(4-Amino-2-ethyl-1H-imidazoÄ4,5-cÜchinolin-1-yl)butylÜmethanesulfonamide, diese enthaltende pharmazeutische Zusammensetzung und deren Verwendung |
| WO2004080430A2 (en) * | 2003-03-13 | 2004-09-23 | 3M Innovative Properties Company | Methods of improving skin quality |
| CA2467828C (en) * | 2001-11-29 | 2011-10-04 | 3M Innovative Properties Company | Pharmaceutical formulations comprising an immune response modifier |
| US6677349B1 (en) * | 2001-12-21 | 2004-01-13 | 3M Innovative Properties Company | Sulfonamide and sulfamide substituted imidazoquinolines |
| PT1478327E (pt) * | 2002-02-22 | 2015-08-04 | Meda Ab | Método de redução e tratamento de imunossupressão induzida por uvb |
| GB0211649D0 (en) * | 2002-05-21 | 2002-07-03 | Novartis Ag | Organic compounds |
| AU2003233519A1 (en) * | 2002-05-29 | 2003-12-19 | 3M Innovative Properties Company | Process for imidazo(4,5-c)pyridin-4-amines |
| JP2005538057A (ja) * | 2002-06-07 | 2005-12-15 | スリーエム イノベイティブ プロパティズ カンパニー | エーテル置換イミダゾピリジン |
| DK1543002T3 (da) * | 2002-07-23 | 2006-12-27 | Teva Gyogyszergyar Zartkoeruee | Fremstilling af 1H-imidazo (4,5-c) quinolin-4-aminer via 1H-imidazo (4,5-c) quinolin-4-phtalimid mellemprodukter |
| PL374866A1 (en) * | 2002-07-26 | 2005-11-14 | Teva Gyogyszergyar Zartköruen Muködo Reszvenytarsasag | Preparation of 1h-imidazo [4,5-c] quinolin-4-amines via novel 1h-imidazo [4,5-c] quinolin-4-cyano and 1h-imidazo [4,5-c] quinolin-4-carboxamide intermediates |
| US7427629B2 (en) * | 2002-08-15 | 2008-09-23 | 3M Innovative Properties Company | Immunostimulatory compositions and methods of stimulating an immune response |
| JP2006503068A (ja) * | 2002-09-26 | 2006-01-26 | スリーエム イノベイティブ プロパティズ カンパニー | １ｈ−イミダゾダイマー |
| WO2004053057A2 (en) * | 2002-12-11 | 2004-06-24 | 3M Innovative Properties Company | Gene expression systems and recombinant cell lines |
| WO2004053452A2 (en) * | 2002-12-11 | 2004-06-24 | 3M Innovative Properties Company | Assays relating to toll-like receptor activity |
| EP1590348A1 (de) * | 2002-12-20 | 2005-11-02 | 3M Innovative Properties Company | Aryl / hetaryl-substituierte imidazochinoline |
| EP2572714A1 (de) * | 2002-12-30 | 2013-03-27 | 3M Innovative Properties Company | Immunstimulatorische Kombinationen |
| WO2004071459A2 (en) * | 2003-02-13 | 2004-08-26 | 3M Innovative Properties Company | Methods and compositions related to irm compounds and toll-like receptor 8 |
| US7485432B2 (en) * | 2003-02-27 | 2009-02-03 | 3M Innovative Properties Company | Selective modulation of TLR-mediated biological activity |
| EP1601365A4 (de) * | 2003-03-04 | 2009-11-11 | 3M Innovative Properties Co | Prophylaktische behandlung von uv-induzierter epidermaler neoplasie |
| WO2004080398A2 (en) * | 2003-03-07 | 2004-09-23 | 3M Innovative Properties Company | 1-amino 1h-imidazoquinolines |
| AU2004220465A1 (en) * | 2003-03-13 | 2004-09-23 | 3M Innovative Properties Company | Method of tattoo removal |
| JP2006523212A (ja) * | 2003-03-13 | 2006-10-12 | スリーエム イノベイティブ プロパティズ カンパニー | 皮膚病変の診断方法 |
| US20040191833A1 (en) * | 2003-03-25 | 2004-09-30 | 3M Innovative Properties Company | Selective activation of cellular activities mediated through a common toll-like receptor |
| US20040192585A1 (en) * | 2003-03-25 | 2004-09-30 | 3M Innovative Properties Company | Treatment for basal cell carcinoma |
| AU2004244962A1 (en) * | 2003-04-10 | 2004-12-16 | 3M Innovative Properties Company | Delivery of immune response modifier compounds using metal-containing particulate support materials |
| WO2004096144A2 (en) * | 2003-04-28 | 2004-11-11 | 3M Innovative Properties Company | Compositions and methods for induction of opioid receptors |
| ATE465742T1 (de) * | 2003-09-05 | 2010-05-15 | Anadys Pharmaceuticals Inc | Tlr7-liganden zur behandlung von hepatitis c |
| WO2005033049A2 (en) * | 2003-10-01 | 2005-04-14 | Taro Pharmaceuticals U.S.A., Inc. | METHOD OF PREPARING 4-AMINO-1H-IMIDAZO(4,5-c)QUINOLINES AND ACID ADDITION SALTS THEREOF |
| ITMI20032121A1 (it) * | 2003-11-04 | 2005-05-05 | Dinamite Dipharma Spa In Forma Abbr Eviata Dipharm | Procedimento per la preparazione di imiquimod e suoi intermedi |
| WO2005048933A2 (en) * | 2003-11-14 | 2005-06-02 | 3M Innovative Properties Company | Oxime substituted imidazo ring compounds |
| TW200638931A (en) * | 2005-02-04 | 2006-11-16 | 3M Innovative Properties Co | Aqueous gel formulations containing 1-(2-methylpropyl)-1H-imidazo[4,5-C][1,5]naphthyridin-4-amine |
-
2005
- 2005-12-18 US US11/794,584 patent/US8436176B2/en not_active Expired - Fee Related
- 2005-12-28 DK DK05855868.5T patent/DK1833827T3/da active
- 2005-12-28 BR BRPI0519797-0A patent/BRPI0519797A/pt not_active Application Discontinuation
- 2005-12-28 PT PT05855868T patent/PT1833827E/pt unknown
- 2005-12-28 AU AU2005322844A patent/AU2005322844A1/en not_active Abandoned
- 2005-12-28 RU RU2007129092/04A patent/RU2388760C2/ru active
- 2005-12-28 WO PCT/US2005/047068 patent/WO2006071862A2/en not_active Ceased
- 2005-12-28 JP JP2007549617A patent/JP2008526758A/ja active Pending
- 2005-12-28 AT AT05855868T patent/ATE510838T1/de active
- 2005-12-28 CA CA002592898A patent/CA2592898A1/en not_active Abandoned
- 2005-12-28 EP EP05855868A patent/EP1833827B9/de not_active Expired - Lifetime
- 2005-12-28 PL PL05855868T patent/PL1833827T3/pl unknown
- 2005-12-28 MX MX2007008131A patent/MX2007008131A/es active IP Right Grant
- 2005-12-28 WO PCT/US2005/047375 patent/WO2006074046A2/en not_active Ceased
- 2005-12-28 CA CA002592957A patent/CA2592957A1/en not_active Abandoned
- 2005-12-28 JP JP2007549551A patent/JP2008535777A/ja not_active Withdrawn
- 2005-12-28 US US11/813,007 patent/US20090124652A1/en not_active Abandoned
- 2005-12-28 EP EP05857217A patent/EP1833833A2/de not_active Withdrawn
-
2007
- 2007-06-28 IL IL184310A patent/IL184310A/en active IP Right Grant
- 2007-06-29 CR CR9217A patent/CR9217A/es unknown
- 2007-12-21 NO NO20076651A patent/NO339859B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1833827A2 (de) | 2007-09-19 |
| PL1833827T3 (pl) | 2011-10-31 |
| RU2007129092A (ru) | 2009-02-10 |
| NO339859B1 (no) | 2017-02-06 |
| MX2007008131A (es) | 2008-04-29 |
| WO2006071862A3 (en) | 2007-07-05 |
| WO2006074046A2 (en) | 2006-07-13 |
| JP2008526758A (ja) | 2008-07-24 |
| WO2006074046A3 (en) | 2007-08-16 |
| US20080306266A1 (en) | 2008-12-11 |
| WO2006071862A2 (en) | 2006-07-06 |
| US20090124652A1 (en) | 2009-05-14 |
| CA2592957A1 (en) | 2006-07-13 |
| RU2388760C2 (ru) | 2010-05-10 |
| CA2592898A1 (en) | 2006-07-06 |
| IL184310A (en) | 2011-12-29 |
| IL184310A0 (en) | 2007-10-31 |
| NO20076651L (no) | 2007-12-21 |
| DK1833827T3 (da) | 2011-09-05 |
| CR9217A (es) | 2008-08-26 |
| EP1833833A2 (de) | 2007-09-19 |
| PT1833827E (pt) | 2011-08-23 |
| EP1833827B1 (de) | 2011-05-25 |
| EP1833827A4 (de) | 2009-11-11 |
| JP2008535777A (ja) | 2008-09-04 |
| EP1833827B9 (de) | 2012-01-04 |
| US8436176B2 (en) | 2013-05-07 |
| AU2005322844A1 (en) | 2006-07-13 |
| BRPI0519797A (pt) | 2008-08-05 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20076651L (no) | Fremgangsmate for fremstilling av 2-metyl-l-(2-metylpropyl)-1H-imidazo[4,5-c] [1,5]naftyridin-4-amin | |
| DE502004009763D1 (de) | Verfahren zur herstellung von 1-buten | |
| ATE469908T1 (de) | Verfahren zur herstellung von pimecrolimus | |
| DE502004009142D1 (de) | Verfahren zur herstellung substituierter 3-aryl-butyl-aminverbindungen | |
| ATE340819T1 (de) | Verfahren zur herstellung von polyamiden | |
| DE602004010234D1 (de) | Verfahren zur herstellung von 4-aminodiphenylamin | |
| ATE435209T1 (de) | Verfahren zur herstellung von montelukast-natrium | |
| ATE515500T1 (de) | Verfahren zur herstellung von telmisartan | |
| ATE542803T1 (de) | Verfahren zur herstellung von dihydrochinazolinen | |
| ATE482966T1 (de) | Verfahren zur herstellung von 7-alpha-alkylierte 19-norsteroide | |
| DE602004005137D1 (de) | Verfahren zur Herstellung von Nanopartikeln | |
| ATE376997T1 (de) | Verfahren zur herstellung von 1,4- diphenylazetidinon-derivaten | |
| ATE358172T1 (de) | Verfahren zur herstellung von olefinen. | |
| DE602005014280D1 (de) | Verfahren zur herstellung von ä1,4,5ü-oxadiazepinderivaten | |
| DE602004004677D1 (de) | Verfahren zur herstellung substituierter 5-amino-pyrazolo-ä4,3-eü-1,2,4-triazoloä1,5-cüpyrimidine | |
| DE602006014677D1 (de) | Verfahren zur herstellung 1-substituierter 1h-imidazoä4,5-cüchinolin-4-aminverbindungen und zwischenprodukte dafür | |
| ATE501282T1 (de) | Verfahren zur herstellung von konzentraten | |
| DE502004002810D1 (de) | Verfahren zur herstellung von copolymerisaten | |
| DE602004005239D1 (de) | Verfahren zur herstellung von tubulininhibitoren | |
| DE602004027840D1 (de) | Verfahren zur herstellung von thiazolopyrimidinen | |
| DE60301444D1 (de) | Verfahren zur Herstellung von Polyalkylphenoxyaminoalkanen | |
| EP1720840A4 (de) | Verfahren zur herstellung von 1,3-dioxolannukleosiden | |
| DE602004018447D1 (de) | Verfahren zur Herstellung von Alkylbenzaldehyden | |
| DE602004025752D1 (de) | Verfahren zur herstellung von 4,4,4-trifluorbutan-2-on | |
| ATE396166T1 (de) | Verfahren zur herstellung von 2,3-cis- substituierten 2-arylpropenalen |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1833827 Country of ref document: EP |