ATE87306T1 - Prolinalderivate. - Google Patents
Prolinalderivate.Info
- Publication number
- ATE87306T1 ATE87306T1 AT88101186T AT88101186T ATE87306T1 AT E87306 T1 ATE87306 T1 AT E87306T1 AT 88101186 T AT88101186 T AT 88101186T AT 88101186 T AT88101186 T AT 88101186T AT E87306 T1 ATE87306 T1 AT E87306T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- carbon atom
- amnesia
- chem
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2240787 | 1987-02-04 | ||
| EP88101186A EP0277588B1 (de) | 1987-02-04 | 1988-01-27 | Prolinalderivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE87306T1 true ATE87306T1 (de) | 1993-04-15 |
Family
ID=12081811
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT88101186T ATE87306T1 (de) | 1987-02-04 | 1988-01-27 | Prolinalderivate. |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US4977180A (de) |
| EP (1) | EP0277588B1 (de) |
| KR (1) | KR960004858B1 (de) |
| AT (1) | ATE87306T1 (de) |
| DE (1) | DE3879522T2 (de) |
| ES (1) | ES2054712T3 (de) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1990012005A1 (fr) * | 1989-04-13 | 1990-10-18 | Japan Tobacco Inc. | Nouveaux derives aminoacides possedant une activite d'inhibiteur de la prolylendopeptidase |
| WO1991018891A1 (en) * | 1990-06-04 | 1991-12-12 | Pfizer Inc. | Aromatic pyrrolidine and thiazolidine amides |
| JP4806628B2 (ja) | 2003-05-05 | 2011-11-02 | プロビオドルグ エージー | グルタミニルシクラーゼ阻害剤 |
| WO2005049027A2 (en) | 2003-11-03 | 2005-06-02 | Probiodrug Ag | Combinations useful for the treatment of neuronal disorders |
| KR101099206B1 (ko) | 2004-02-05 | 2011-12-27 | 프로비오드룩 아게 | 신규한 글루타미닐 시클라제 저해제 |
| US8278345B2 (en) | 2006-11-09 | 2012-10-02 | Probiodrug Ag | Inhibitors of glutaminyl cyclase |
| JP5523107B2 (ja) | 2006-11-30 | 2014-06-18 | プロビオドルグ エージー | グルタミニルシクラーゼの新規阻害剤 |
| EP2481408A3 (de) | 2007-03-01 | 2013-01-09 | Probiodrug AG | Neue Verwendung von Inhibitoren der Glutaminyl Cyclase |
| WO2008128985A1 (en) | 2007-04-18 | 2008-10-30 | Probiodrug Ag | Thiourea derivatives as glutaminyl cyclase inhibitors |
| WO2008144748A1 (en) * | 2007-05-21 | 2008-11-27 | The Uab Research Foundation | Prolyl endopeptidase inhibitors for reducing or preventing neutrophilic inflammation |
| MX2012002993A (es) | 2009-09-11 | 2012-04-19 | Probiodrug Ag | Derivados heterociclicos como inhibidores de ciclasa glutaminilo. |
| JP6026284B2 (ja) | 2010-03-03 | 2016-11-16 | プロビオドルグ エージー | グルタミニルシクラーゼの阻害剤 |
| US8269019B2 (en) | 2010-03-10 | 2012-09-18 | Probiodrug Ag | Inhibitors |
| WO2011131748A2 (en) | 2010-04-21 | 2011-10-27 | Probiodrug Ag | Novel inhibitors |
| ES2570167T3 (es) | 2011-03-16 | 2016-05-17 | Probiodrug Ag | Derivados de benzimidazol como inhibidores de glutaminil ciclasa |
| US9477350B2 (en) | 2011-04-26 | 2016-10-25 | Sentons Inc. | Method and apparatus for active ultrasonic touch devices |
| US9189109B2 (en) | 2012-07-18 | 2015-11-17 | Sentons Inc. | Detection of type of object used to provide a touch contact input |
| US9639213B2 (en) | 2011-04-26 | 2017-05-02 | Sentons Inc. | Using multiple signals to detect touch input |
| US10198097B2 (en) | 2011-04-26 | 2019-02-05 | Sentons Inc. | Detecting touch input force |
| US11327599B2 (en) | 2011-04-26 | 2022-05-10 | Sentons Inc. | Identifying a contact type |
| US9099971B2 (en) | 2011-11-18 | 2015-08-04 | Sentons Inc. | Virtual keyboard interaction using touch input force |
| EP2780782B1 (de) | 2011-11-18 | 2020-05-13 | Sentons Inc. | Lokalisiertes haptisches feedback |
| US9459715B1 (en) | 2013-09-20 | 2016-10-04 | Sentons Inc. | Using spectral control in detecting touch input |
| US10048811B2 (en) | 2015-09-18 | 2018-08-14 | Sentons Inc. | Detecting touch input provided by signal transmitting stylus |
| US10908741B2 (en) | 2016-11-10 | 2021-02-02 | Sentons Inc. | Touch input detection along device sidewall |
| US10296144B2 (en) | 2016-12-12 | 2019-05-21 | Sentons Inc. | Touch input detection with shared receivers |
| US10126877B1 (en) | 2017-02-01 | 2018-11-13 | Sentons Inc. | Update of reference data for touch input detection |
| US10585522B2 (en) | 2017-02-27 | 2020-03-10 | Sentons Inc. | Detection of non-touch inputs using a signature |
| US11009411B2 (en) | 2017-08-14 | 2021-05-18 | Sentons Inc. | Increasing sensitivity of a sensor using an encoded signal |
| PL3461819T3 (pl) | 2017-09-29 | 2020-11-30 | Probiodrug Ag | Inhibitory cyklazy glutaminylowej |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60188317A (ja) * | 1984-03-09 | 1985-09-25 | Yakult Honsha Co Ltd | 抗健忘症剤 |
| JPS6137764A (ja) * | 1984-07-31 | 1986-02-22 | Suntory Ltd | 抗プロリルエンドペプチダ−ゼ活性を有する新規生理活性化合物 |
| JPH0680077B2 (ja) * | 1985-02-08 | 1994-10-12 | サントリー株式会社 | プロリンエンドペプチダ−ゼインヒビタ−活性を有する新規ペプチド化合物 |
| US4873342A (en) * | 1985-04-16 | 1989-10-10 | Suntory Limited | Dipeptide derivative and synthesis and use thereof |
| US4772587A (en) * | 1985-04-16 | 1988-09-20 | Suntory Limited | Dipeptide derivative of fatty acid |
| JPH0623190B2 (ja) * | 1985-04-16 | 1994-03-30 | サントリー株式会社 | インヒビタ−活性を有するｎ−アシルピロリジン誘導体及びその製法並びに用途 |
| EP0268190B1 (de) * | 1986-11-20 | 1993-06-16 | Ono Pharmaceutical Co., Ltd. | Prolinalderivate |
| DE3783754T2 (de) * | 1986-12-29 | 1993-08-05 | Ono Pharmaceutical Co | Prolin-derivate. |
| JPH0366162A (ja) * | 1989-08-04 | 1991-03-20 | Hitachi Ltd | 固体撮像装置 |
-
1988
- 1988-01-27 DE DE8888101186T patent/DE3879522T2/de not_active Expired - Fee Related
- 1988-01-27 ES ES88101186T patent/ES2054712T3/es not_active Expired - Lifetime
- 1988-01-27 EP EP88101186A patent/EP0277588B1/de not_active Expired - Lifetime
- 1988-01-27 AT AT88101186T patent/ATE87306T1/de not_active IP Right Cessation
- 1988-02-03 KR KR1019880000965A patent/KR960004858B1/ko not_active Expired - Fee Related
- 1988-02-03 US US07/151,862 patent/US4977180A/en not_active Expired - Lifetime
-
1990
- 1990-02-07 US US07/479,493 patent/US5091406A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5091406A (en) | 1992-02-25 |
| EP0277588B1 (de) | 1993-03-24 |
| US4977180A (en) | 1990-12-11 |
| KR880009922A (ko) | 1988-10-05 |
| EP0277588A1 (de) | 1988-08-10 |
| ES2054712T3 (es) | 1994-08-16 |
| DE3879522D1 (de) | 1993-04-29 |
| DE3879522T2 (de) | 1993-09-02 |
| KR960004858B1 (ko) | 1996-04-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |