ATE92523T1 - Verfahren zur abtrennung und reinigung von sialyl-transferasen. - Google Patents

Verfahren zur abtrennung und reinigung von sialyl-transferasen.

Info

Publication number: ATE92523T1
Authority: AT; Austria
Prior art keywords: specific; sialyl; methods; lases; purification
Prior art date: 1989-04-12

Application number

AT90906090T

Other languages

English (en)

Inventor

M Abdul Mazid

Mohammed A Kashem

Original Assignee

Chembiomed Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-12

Filing date

1990-04-12

Publication date

1993-08-15

1990-04-12 Application filed by Chembiomed Ltd filed Critical Chembiomed Ltd

1993-08-15 Application granted granted Critical

1993-08-15 Publication of ATE92523T1 publication Critical patent/ATE92523T1/de

Links

238000000034 method Methods 0.000 title abstract 3
238000000746 purification Methods 0.000 title 1
238000000926 separation method Methods 0.000 title 1
102000003838 Sialyltransferases Human genes 0.000 abstract 4
108090000141 Sialyltransferases Proteins 0.000 abstract 4
KFEUJDWYNGMDBV-LODBTCKLSA-N N-acetyllactosamine Chemical compound O[C@@H]1[C@@H](NC(=O)C)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KFEUJDWYNGMDBV-LODBTCKLSA-N 0.000 abstract 2
HESSGHHCXGBPAJ-UHFFFAOYSA-N N-acetyllactosamine Natural products CC(=O)NC(C=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O HESSGHHCXGBPAJ-UHFFFAOYSA-N 0.000 abstract 2
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
125000000837 carbohydrate group Chemical group 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
239000000758 substrate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
- Y10S435/815—Enzyme separation or purification by sorption

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Enzymes And Modification Thereof (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

AT90906090T 1989-04-12 1990-04-12 Verfahren zur abtrennung und reinigung von sialyl-transferasen. ATE92523T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/336,932 US5059535A (en)	1989-04-12	1989-04-12	Process for the separation and purification of sialyl transferases
PCT/CA1990/000124 WO1990012090A1 (en)	1989-04-12	1990-04-12	Process for the separation and purification of sialyl transferases

Publications (1)

Publication Number	Publication Date
ATE92523T1 true ATE92523T1 (de)	1993-08-15

Family

ID=23318345

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT90906090T ATE92523T1 (de)	1989-04-12	1990-04-12	Verfahren zur abtrennung und reinigung von sialyl-transferasen.

Country Status (10)

Country	Link
US (1)	US5059535A (de)
EP (1)	EP0470969B1 (de)
JP (1)	JPH05500154A (de)
AT (1)	ATE92523T1 (de)
AU (1)	AU633912B2 (de)
CA (1)	CA2051374C (de)
DE (1)	DE69002623T2 (de)
DK (1)	DK0470969T3 (de)
ES (1)	ES2058908T3 (de)
WO (1)	WO1990012090A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5079353A (en) *	1987-12-02	1992-01-07	Chembiomed, Ltd.	Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
DE4009630C2 (de) *	1990-03-26	1995-09-28	Reinhard Prof Dr Dr Brossmer	CMP-aktivierte fluoreszierende Sialinsäuren sowie Verfahren zu ihrer Herstellung
US5374655A (en) *	1991-06-10	1994-12-20	Alberta Research Council	Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures
CA2110582C (en) *	1991-06-10	2001-02-27	Andre P. Venot	Modified sialyl lewis a compounds
US5646123A (en) *	1991-06-10	1997-07-08	Alberta Research Council	Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen
US5352670A (en) *	1991-06-10	1994-10-04	Alberta Research Council	Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
CA2110797C (en) *	1991-06-10	2001-02-20	Andre P. Venot	Modified sialyl lewis x compounds
DK0632831T3 (da) *	1992-03-09	2003-03-24	Univ California	Nukleinsyre, ekspressionsvektor og sammensætninger til identificering og syntese af rekombinante sialyltransferaser
WO1995018217A1 (en) *	1993-12-24	1995-07-06	The Institute Of Physical And Chemical Research	Novel sugar-chain synthetase and process for producing the same
US7214660B2 (en)	2001-10-10	2007-05-08	Neose Technologies, Inc.	Erythropoietin: remodeling and glycoconjugation of erythropoietin
NZ542586A (en)	2003-04-09	2009-11-27	Biogenerix Ag	Method of forming a covalent conjugate between a G-CSF peptide and PEG
US9005625B2 (en)	2003-07-25	2015-04-14	Novo Nordisk A/S	Antibody toxin conjugates
US20080305992A1 (en)	2003-11-24	2008-12-11	Neose Technologies, Inc.	Glycopegylated erythropoietin
EP3061461A1 (de)	2004-10-29	2016-08-31	ratiopharm GmbH	Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf)
US9029331B2 (en)	2005-01-10	2015-05-12	Novo Nordisk A/S	Glycopegylated granulocyte colony stimulating factor
EP1871795A4 (de)	2005-04-08	2010-03-31	Biogenerix Ag	Zusammensetzungen und verfahren zur herstellung von glycosylierungsmutanten eines proteaseresistenten menschlichen wachstumshormons
US20070105755A1 (en)	2005-10-26	2007-05-10	Neose Technologies, Inc.	One pot desialylation and glycopegylation of therapeutic peptides
WO2007056191A2 (en)	2005-11-03	2007-05-18	Neose Technologies, Inc.	Nucleotide sugar purification using membranes
US20080242607A1 (en)	2006-07-21	2008-10-02	Neose Technologies, Inc.	Glycosylation of peptides via o-linked glycosylation sequences
US8969532B2 (en)	2006-10-03	2015-03-03	Novo Nordisk A/S	Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
CN101796063B (zh)	2007-04-03	2017-03-22	拉蒂奥法姆有限责任公司	使用糖聚乙二醇化g‑csf的治疗方法
US9493499B2 (en)	2007-06-12	2016-11-15	Novo Nordisk A/S	Process for the production of purified cytidinemonophosphate-sialic acid-polyalkylene oxide (CMP-SA-PEG) as modified nucleotide sugars via anion exchange chromatography
DE102008005159B4 (de)	2008-01-18	2018-02-15	Robert Bosch Gmbh	Verfahren und Steuergerät zur Ansteuerung von Personenschutzmittel für ein Fahrzeug
DK2257311T3 (da)	2008-02-27	2014-06-30	Novo Nordisk As	Konjugerede Faktor VIII-Molekyler
US12622876B2 (en) *	2016-08-22	2026-05-12	Lonza Sales Ag	Methods of suppressing delivery of exosomes to liver and spleen
CA3181285A1 (en) *	2020-07-20	2022-01-27	Jessica BASSO	Methods for extracting neutrophil serine proteases and treating dipeptidyl peptidase 1-mediated conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4250262A (en) *	1979-12-14	1981-02-10	Forsyth Dental Infirmary For Children	Method of preparing a purified glucosyltransferase
JPS58209980A (ja) *	1982-04-27	1983-12-07	Kyowa Hakko Kogyo Co Ltd	酵素の精製法
EP0263533A3 (de) *	1983-03-01	1990-05-30	C.R.C. Compagnia di Ricerca Chimica S.p.A.	Verfahren zur Herstellung von Cytidinmonophosphat von 5-Acetamido-3,5-dideoxy-D-glycero-D-galactononulosaminsaeure
US4925796A (en) *	1986-03-07	1990-05-15	Massachusetts Institute Of Technology	Method for enhancing glycoprotein stability

1989
- 1989-04-12 US US07/336,932 patent/US5059535A/en not_active Expired - Fee Related
1990
- 1990-04-12 WO PCT/CA1990/000124 patent/WO1990012090A1/en not_active Ceased
- 1990-04-12 CA CA002051374A patent/CA2051374C/en not_active Expired - Fee Related
- 1990-04-12 ES ES90906090T patent/ES2058908T3/es not_active Expired - Lifetime
- 1990-04-12 DK DK90906090.7T patent/DK0470969T3/da active
- 1990-04-12 AU AU55289/90A patent/AU633912B2/en not_active Ceased
- 1990-04-12 EP EP90906090A patent/EP0470969B1/de not_active Expired - Lifetime
- 1990-04-12 JP JP2506291A patent/JPH05500154A/ja active Pending
- 1990-04-12 AT AT90906090T patent/ATE92523T1/de not_active IP Right Cessation
- 1990-04-12 DE DE90906090T patent/DE69002623T2/de not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU633912B2 (en)	1993-02-11
US5059535A (en)	1991-10-22
CA2051374C (en)	1996-02-27
WO1990012090A1 (en)	1990-10-18
ES2058908T3 (es)	1994-11-01
JPH05500154A (ja)	1993-01-21
EP0470969B1 (de)	1993-08-04
DE69002623D1 (de)	1993-09-09
AU5528990A (en)	1990-11-05
EP0470969A1 (de)	1992-02-19
DK0470969T3 (da)	1994-01-03
DE69002623T2 (de)	1993-11-25
CA2051374A1 (en)	1990-10-13

Legal Events

Date	Code	Title
1994-02-15	EEIH	Change in the person of patent owner
1994-12-15	UEP	Publication of translation of european patent specification
2000-01-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
DK0470969T3 (da)	1994-01-03	Fremgangsmåde til adskillelse og rensning af sialyltransferaser
OA08481A (fr)	1988-07-29	Dérivés d'indolizine, leur procédé de préparation ainsi que les compositions les contenant.
FR2637612B1 (fr)	1993-09-10	Sequences de nucleotides codant pour une proteine a activite ureasique
NO852567L (no)	1985-12-30	Thymopentinanaloger og fremgangsmmaate for deres fremstilling.
NO165495C (no)	1991-02-20	Analogifremgangsmaate for fremstilling av terapeutisk aktive n6-substituerte deoksyriboseanaloger av adenosiner.
PT87191A (pt)	1988-05-01	Process for the preparation of nucleosides
IT8719262A0 (it)	1987-02-05	Procedimento per la disproporzione di toluene.
ES2072251T3 (es)	1995-07-16	Composiciones y metodos para la sintesis y ensayo de enquefalinasa.
EP0304215A3 (de)	1990-05-23	Phosphorylierungsreagenz und Verfahren zu seiner Verwendung
ATE85363T1 (de)	1993-02-15	Verfahren und reagenz zur bestimmung von alphaamylase.
DE69735583D1 (de)	2006-05-18	Semisynthetisches verfahren zur herstellung von didemninanalogen
FR2575466B1 (fr)	1987-02-20	Nouveaux complexes de silicium hexacoordines, leur procede de preparation et leur application
FI881413A0 (fi)	1988-03-24	Foerfarande foer framstaellning av 3'-azido-3'-deoxitymidin.
DK167384D0 (da)	1984-03-26	Penemer,farmaceutiske praeparater indeholdende disse,samt fremgangsmaader til fremstilling deraf
IT8621312A0 (it)	1986-07-30	Procedimento di (co)polimerizzazioni di alfa olefine in presenta di stabilizzanti.
DE59005334D1 (de)	1994-05-19	Verfahren zur Herstellung von reinem Guanin.
ATE49185T1 (de)	1990-01-15	Verfahren zur herstellung von halogen-magnesium- alanat und dessen verwendung.
IT8120231A0 (it)	1981-03-09	Procedimento per la produzione di enzima fruttosil transferasi.
DE69109347D1 (de)	1995-06-08	Verfahren zur Herstellung linearer alpha-Olefine.
IT8820117A0 (it)	1988-04-07	Procedimento per la preparazione di bis(2,2,6,6_tetrametil_4_piperidil)ammina.
NO880993D0 (no)	1988-03-04	Fremgangsmaate for fremstilling av silan- eller siloxanforbindelser inneholdende minst en cykloalkylring.
FR2653771B1 (fr)	1994-09-23	Procede de preparation de l'azt (azido-3'-desoxy-3'-thymidine) et de composes apparentes.
IT1190116B (it)	1988-02-10	Processo per la sintesi di mono o di idrossifluoroalcani
FR2595697B1 (fr)	1988-07-08	Derives de benzyl-pyrimidine, leur procede de preparation ainsi que les compositions en contenant
DE3853269D1 (de)	1995-04-13	Temperaturkontrolliertes Verfahren zur Herstellung von als Adjuvans für Detergentien verwendbaren 2'2'-Oxodisuccinten.