DK0470969T3 - Fremgangsmåde til adskillelse og rensning af sialyltransferaser - Google Patents

Fremgangsmåde til adskillelse og rensning af sialyltransferaser

Info

Publication number: DK0470969T3
Authority: DK; Denmark
Prior art keywords: specific; sialyl; purifying; separating; lacnac
Prior art date: 1989-04-12

Application number

DK90906090.7T

Other languages

Danish (da)

English (en)

Inventor

M Abdul Mazid

Mohammed A Kashem

Original Assignee

Alberta Res Council

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-12

Filing date

1990-04-12

Publication date

1994-01-03

1990-04-12 Application filed by Alberta Res Council filed Critical Alberta Res Council

1994-01-03 Application granted granted Critical

1994-01-03 Publication of DK0470969T3 publication Critical patent/DK0470969T3/da

Links

102000003838 Sialyltransferases Human genes 0.000 title abstract 5
108090000141 Sialyltransferases Proteins 0.000 title abstract 5
238000000034 method Methods 0.000 title abstract 3
KFEUJDWYNGMDBV-LODBTCKLSA-N N-acetyllactosamine Chemical compound O[C@@H]1[C@@H](NC(=O)C)[C@H](O)O[C@H](CO)[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H](O)[C@@H](CO)O1 KFEUJDWYNGMDBV-LODBTCKLSA-N 0.000 abstract 2
HESSGHHCXGBPAJ-UHFFFAOYSA-N N-acetyllactosamine Natural products CC(=O)NC(C=O)C(O)C(C(O)CO)OC1OC(CO)C(O)C(O)C1O HESSGHHCXGBPAJ-UHFFFAOYSA-N 0.000 abstract 2
102000004190 Enzymes Human genes 0.000 abstract 1
108090000790 Enzymes Proteins 0.000 abstract 1
125000000837 carbohydrate group Chemical group 0.000 abstract 1
238000002955 isolation Methods 0.000 abstract 1
238000004519 manufacturing process Methods 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
239000000758 substrate Substances 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/814—Enzyme separation or purification
- Y10S435/815—Enzyme separation or purification by sorption

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Microbiology (AREA)
Biotechnology (AREA)
Biomedical Technology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Enzymes And Modification Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Saccharide Compounds (AREA)

DK90906090.7T 1989-04-12 1990-04-12 Fremgangsmåde til adskillelse og rensning af sialyltransferaser DK0470969T3 (da)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/336,932 US5059535A (en)	1989-04-12	1989-04-12	Process for the separation and purification of sialyl transferases

Publications (1)

Publication Number	Publication Date
DK0470969T3 true DK0470969T3 (da)	1994-01-03

Family

ID=23318345

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK90906090.7T DK0470969T3 (da)	1989-04-12	1990-04-12	Fremgangsmåde til adskillelse og rensning af sialyltransferaser

Country Status (10)

Country	Link
US (1)	US5059535A (de)
EP (1)	EP0470969B1 (de)
JP (1)	JPH05500154A (de)
AT (1)	ATE92523T1 (de)
AU (1)	AU633912B2 (de)
CA (1)	CA2051374C (de)
DE (1)	DE69002623T2 (de)
DK (1)	DK0470969T3 (de)
ES (1)	ES2058908T3 (de)
WO (1)	WO1990012090A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5079353A (en) *	1987-12-02	1992-01-07	Chembiomed, Ltd.	Sialic acid glycosides, antigens, immunoadsorbents, and methods for their preparation
DE4009630C2 (de) *	1990-03-26	1995-09-28	Reinhard Prof Dr Dr Brossmer	CMP-aktivierte fluoreszierende Sialinsäuren sowie Verfahren zu ihrer Herstellung
US5374655A (en) *	1991-06-10	1994-12-20	Alberta Research Council	Methods for the synthesis of monofucosylated oligosaccharides terminating in di-N-acetyllactosaminyl structures
EP0589951A1 (de) *	1991-06-10	1994-04-06	Glycomed Incorporated	Modifizierte Sialyl Lewis X-Verbindungen
JPH06510745A (ja) *	1991-06-10	1994-12-01	グライカムド　インコーポレイテッド	修飾シアリルルイスａ化合物
US5352670A (en) *	1991-06-10	1994-10-04	Alberta Research Council	Methods for the enzymatic synthesis of alpha-sialylated oligosaccharide glycosides
US5646123A (en) *	1991-06-10	1997-07-08	Alberta Research Council	Time dependent administration of oligosaccharide glycosides related to blood group determinants having a type I or type II core structure in reducing inflammation in a sensitized mammal arising form exposure to an antigen
ATE228565T1 (de) *	1992-03-09	2002-12-15	Univ California	Nukleinsäure, expressionsvektor und zusammensetzungen zur identifizierung und herstellung von rekombinanten sialyltransferasen
WO1995018217A1 (en)	1993-12-24	1995-07-06	The Institute Of Physical And Chemical Research	Novel sugar-chain synthetase and process for producing the same
US7214660B2 (en)	2001-10-10	2007-05-08	Neose Technologies, Inc.	Erythropoietin: remodeling and glycoconjugation of erythropoietin
CA2522345A1 (en)	2003-04-09	2004-11-18	Neose Technologies, Inc.	Glycopegylation methods and proteins/peptides produced by the methods
WO2005012484A2 (en)	2003-07-25	2005-02-10	Neose Technologies, Inc.	Antibody-toxin conjugates
US20080305992A1 (en)	2003-11-24	2008-12-11	Neose Technologies, Inc.	Glycopegylated erythropoietin
EP1814573B1 (de)	2004-10-29	2016-03-09	ratiopharm GmbH	Remodellierung und glykopegylierung von fibroblasten-wachstumsfaktor (fgf)
CA2593682C (en)	2005-01-10	2016-03-22	Neose Technologies, Inc.	Glycopegylated granulocyte colony stimulating factor
US9187546B2 (en)	2005-04-08	2015-11-17	Novo Nordisk A/S	Compositions and methods for the preparation of protease resistant human growth hormone glycosylation mutants
US20070105755A1 (en)	2005-10-26	2007-05-10	Neose Technologies, Inc.	One pot desialylation and glycopegylation of therapeutic peptides
US20090048440A1 (en)	2005-11-03	2009-02-19	Neose Technologies, Inc.	Nucleotide Sugar Purification Using Membranes
CN101516388B (zh)	2006-07-21	2012-10-31	诺和诺德公司	通过o-联糖基化序列的肽的糖基化
US8969532B2 (en)	2006-10-03	2015-03-03	Novo Nordisk A/S	Methods for the purification of polypeptide conjugates comprising polyalkylene oxide using hydrophobic interaction chromatography
EP2144923B1 (de)	2007-04-03	2013-02-13	BioGeneriX AG	Behandlungsverfahren mit glycopegyliertem g-csf
WO2008154639A2 (en)	2007-06-12	2008-12-18	Neose Technologies, Inc.	Improved process for the production of nucleotide sugars
DE102008005159B4 (de)	2008-01-18	2018-02-15	Robert Bosch Gmbh	Verfahren und Steuergerät zur Ansteuerung von Personenschutzmittel für ein Fahrzeug
US20130189239A1 (en)	2008-02-27	2013-07-25	Novo Nordisk A/S	Conjugated Factor VIII Molecules
EP3500244B1 (de) *	2016-08-22	2026-07-08	Lonza Sales AG	Verfahren zur unterdrückung der abgabe von exosomen an die leber und die milz
AU2021314104A1 (en) *	2020-07-20	2023-01-19	Insmed, Inc.	Methods for extracting neutrophil serine proteases and treating dipeptidyl peptidase 1-mediated conditions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4250262A (en) *	1979-12-14	1981-02-10	Forsyth Dental Infirmary For Children	Method of preparing a purified glucosyltransferase
JPS58209980A (ja) *	1982-04-27	1983-12-07	Kyowa Hakko Kogyo Co Ltd	酵素の精製法
ATE37984T1 (de) *	1983-03-01	1988-11-15	Crc Ricerca Chim	Pharmazeutische zusammensetzung welche 5acetamido-3,5-dideoxy-d-glycero-dgalactononulosamins\|ure cytidin monophosphat enthaelt.
US4925796A (en) *	1986-03-07	1990-05-15	Massachusetts Institute Of Technology	Method for enhancing glycoprotein stability

1989
- 1989-04-12 US US07/336,932 patent/US5059535A/en not_active Expired - Fee Related
1990
- 1990-04-12 CA CA002051374A patent/CA2051374C/en not_active Expired - Fee Related
- 1990-04-12 DK DK90906090.7T patent/DK0470969T3/da active
- 1990-04-12 JP JP2506291A patent/JPH05500154A/ja active Pending
- 1990-04-12 DE DE90906090T patent/DE69002623T2/de not_active Expired - Fee Related
- 1990-04-12 AU AU55289/90A patent/AU633912B2/en not_active Ceased
- 1990-04-12 AT AT90906090T patent/ATE92523T1/de not_active IP Right Cessation
- 1990-04-12 ES ES90906090T patent/ES2058908T3/es not_active Expired - Lifetime
- 1990-04-12 WO PCT/CA1990/000124 patent/WO1990012090A1/en not_active Ceased
- 1990-04-12 EP EP90906090A patent/EP0470969B1/de not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU633912B2 (en)	1993-02-11
CA2051374A1 (en)	1990-10-13
DE69002623T2 (de)	1993-11-25
DE69002623D1 (de)	1993-09-09
EP0470969A1 (de)	1992-02-19
ATE92523T1 (de)	1993-08-15
ES2058908T3 (es)	1994-11-01
EP0470969B1 (de)	1993-08-04
CA2051374C (en)	1996-02-27
WO1990012090A1 (en)	1990-10-18
US5059535A (en)	1991-10-22
JPH05500154A (ja)	1993-01-21
AU5528990A (en)	1990-11-05

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