BG106208A - New pharmaceutical combinations for nos inhibitors - Google Patents
New pharmaceutical combinations for nos inhibitorsInfo
- Publication number
- BG106208A BG106208A BG06208A BG10620801A BG106208A BG 106208 A BG106208 A BG 106208A BG 06208 A BG06208 A BG 06208A BG 10620801 A BG10620801 A BG 10620801A BG 106208 A BG106208 A BG 106208A
- Authority
- BG
- Bulgaria
- Prior art keywords
- disorders
- sleep
- inhibitors
- nos
- disorder
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title abstract 4
- 102000008299 Nitric Oxide Synthase Human genes 0.000 abstract 4
- 108010021487 Nitric Oxide Synthase Proteins 0.000 abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 3
- 208000035475 disorder Diseases 0.000 abstract 3
- 208000019888 Circadian rhythm sleep disease Diseases 0.000 abstract 2
- 208000019116 sleep disease Diseases 0.000 abstract 2
- 208000020925 Bipolar disease Diseases 0.000 abstract 1
- 201000004569 Blindness Diseases 0.000 abstract 1
- 208000007590 Disorders of Excessive Somnolence Diseases 0.000 abstract 1
- 208000008967 Enuresis Diseases 0.000 abstract 1
- 208000001456 Jet Lag Syndrome Diseases 0.000 abstract 1
- 102000002002 Neurokinin-1 Receptors Human genes 0.000 abstract 1
- 108010040718 Neurokinin-1 Receptors Proteins 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000006199 Parasomnias Diseases 0.000 abstract 1
- 208000005793 Restless legs syndrome Diseases 0.000 abstract 1
- 208000010340 Sleep Deprivation Diseases 0.000 abstract 1
- 239000013543 active substance Substances 0.000 abstract 1
- 230000002060 circadian Effects 0.000 abstract 1
- 230000027288 circadian rhythm Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 206010020765 hypersomnia Diseases 0.000 abstract 1
- 230000001788 irregular Effects 0.000 abstract 1
- 208000033915 jet lag type circadian rhythm sleep disease Diseases 0.000 abstract 1
- 201000003631 narcolepsy Diseases 0.000 abstract 1
- 208000005346 nocturnal enuresis Diseases 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 230000036385 rapid eye movement (rem) sleep Effects 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 230000033764 rhythmic process Effects 0.000 abstract 1
- 208000012672 seasonal affective disease Diseases 0.000 abstract 1
- 239000012896 selective serotonin reuptake inhibitor Substances 0.000 abstract 1
- 229940124834 selective serotonin reuptake inhibitor Drugs 0.000 abstract 1
- 230000007958 sleep Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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- A61K31/15—Oximes (>C=N—O—); Hydrazines (>N—N<); Hydrazones (>N—N=) ; Imines (C—N=C)
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- A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- Ophthalmology & Optometry (AREA)
- Hospice & Palliative Care (AREA)
- Obesity (AREA)
- Pain & Pain Management (AREA)
- Pulmonology (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US13552099P | 1999-05-21 | 1999-05-21 | |
| PCT/IB2000/000295 WO2000071107A2 (fr) | 1999-05-21 | 2000-03-16 | Nouvelles combinaisons pharmaceutiques pour les inhibiteurs de nos |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG106208A true BG106208A (en) | 2002-09-30 |
Family
ID=22468464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG06208A BG106208A (en) | 1999-05-21 | 2001-12-11 | New pharmaceutical combinations for nos inhibitors |
Country Status (33)
| Country | Link |
|---|---|
| EP (1) | EP1178784A1 (fr) |
| JP (1) | JP2003523941A (fr) |
| KR (1) | KR20020010916A (fr) |
| CN (1) | CN1617743A (fr) |
| AP (1) | AP2001002326A0 (fr) |
| AR (1) | AR022640A1 (fr) |
| AU (1) | AU2935300A (fr) |
| BG (1) | BG106208A (fr) |
| BR (1) | BR0010820A (fr) |
| CA (1) | CA2374668A1 (fr) |
| CO (1) | CO5160295A1 (fr) |
| DZ (1) | DZ3041A1 (fr) |
| EA (1) | EA200101110A1 (fr) |
| EE (1) | EE200100611A (fr) |
| GT (1) | GT200000071A (fr) |
| HN (1) | HN2000000045A (fr) |
| HR (1) | HRP20010862A2 (fr) |
| HU (1) | HUP0301287A3 (fr) |
| IL (1) | IL145955A0 (fr) |
| IS (1) | IS6126A (fr) |
| MA (1) | MA26732A1 (fr) |
| MX (1) | MXPA01011978A (fr) |
| NO (1) | NO20015651L (fr) |
| OA (1) | OA11943A (fr) |
| PA (1) | PA8494601A1 (fr) |
| PE (1) | PE20010157A1 (fr) |
| PL (1) | PL358538A1 (fr) |
| SK (1) | SK16602001A3 (fr) |
| TN (1) | TNSN00106A1 (fr) |
| TR (1) | TR200103351T2 (fr) |
| UY (1) | UY26148A1 (fr) |
| WO (1) | WO2000071107A2 (fr) |
| ZA (1) | ZA200109555B (fr) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE10001785A1 (de) * | 2000-01-18 | 2001-07-19 | Boehringer Ingelheim Pharma | NK¶1¶-Rezeptor-Antagonisten zur Behandlung des Restless Legs Syndroms |
| GB0019006D0 (en) * | 2000-08-04 | 2000-09-20 | Astrazeneca Ab | Novel compounds |
| US20030045449A1 (en) * | 2001-08-15 | 2003-03-06 | Pfizer, Inc. | Pharmaceutical combinations for the treatment of neurodegenerative diseases |
| US6803470B2 (en) * | 2001-10-10 | 2004-10-12 | Pfizer Inc | 2-amino-6-(2,4,5-substituted-phenyl)-pyridines |
| DOP2002000467A (es) * | 2001-10-10 | 2003-04-15 | Pfizer Prod Inc | 2-amino-6 (fenilo sustituido en las posiciones 2,4,5)-piridinas |
| BRPI0411608A (pt) * | 2003-06-24 | 2006-08-08 | Neurosearch As | derivado de 8-aza-biciclo [3.2.1] octano, composição farmacêutica, uso do composto, e, método de tratamento, prevenção ou alìvio de uma doença, um distúrbio ou uma condição de um organismo animal vivo |
| EP1634598A1 (fr) * | 2004-09-07 | 2006-03-15 | Laboratorios Del Dr. Esteve, S.A. | Utilisation de dérivés de piperazine et ses analogues pour prevenir et traiter des désordres liés à l'ingestion de nourriture |
| JO2972B1 (en) | 2007-06-08 | 2016-03-15 | جانسين فارماسوتيكا ان. في | Piperidine / piperazine derivatives |
| EP2152271B1 (fr) | 2007-06-08 | 2015-10-21 | Janssen Pharmaceutica, N.V. | Dérivés de piperidine/piperazine |
| ES2536406T3 (es) | 2007-06-08 | 2015-05-25 | Janssen Pharmaceutica, N.V. | Derivados de piperidina/piperazina |
| JP5464709B2 (ja) | 2007-06-08 | 2014-04-09 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | ピペリジン/ピペラジン誘導体 |
| PE20100083A1 (es) | 2008-06-05 | 2010-02-17 | Janssen Pharmaceutica Nv | Combinaciones de drogas que comprenden un inhibidor de dgat y un agonista de ppar |
| JP5642661B2 (ja) * | 2009-03-05 | 2014-12-17 | 塩野義製薬株式会社 | Npyy5受容体拮抗作用を有するピペリジンおよびピロリジン誘導体 |
| US20140206667A1 (en) | 2012-11-14 | 2014-07-24 | Michela Gallagher | Methods and compositions for treating schizophrenia |
| AU2020291468A1 (en) * | 2019-06-14 | 2022-01-06 | Srx Cardio, Llc | Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) |
| US12115154B2 (en) | 2020-12-16 | 2024-10-15 | Srx Cardio, Llc | Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) |
-
2000
- 2000-03-16 TR TR2001/03351T patent/TR200103351T2/xx unknown
- 2000-03-16 JP JP2000619414A patent/JP2003523941A/ja not_active Withdrawn
- 2000-03-16 HU HU0301287A patent/HUP0301287A3/hu unknown
- 2000-03-16 AP APAP/P/2001/002326A patent/AP2001002326A0/en unknown
- 2000-03-16 MX MXPA01011978A patent/MXPA01011978A/es unknown
- 2000-03-16 HR HR20010862A patent/HRP20010862A2/hr not_active Application Discontinuation
- 2000-03-16 WO PCT/IB2000/000295 patent/WO2000071107A2/fr not_active Ceased
- 2000-03-16 PL PL00358538A patent/PL358538A1/xx not_active Application Discontinuation
- 2000-03-16 EP EP00907891A patent/EP1178784A1/fr not_active Ceased
- 2000-03-16 EA EA200101110A patent/EA200101110A1/ru unknown
- 2000-03-16 AU AU29353/00A patent/AU2935300A/en not_active Abandoned
- 2000-03-16 CN CNA008078785A patent/CN1617743A/zh active Pending
- 2000-03-16 BR BR0010820-0A patent/BR0010820A/pt not_active IP Right Cessation
- 2000-03-16 CA CA002374668A patent/CA2374668A1/fr not_active Abandoned
- 2000-03-16 OA OA1200100301A patent/OA11943A/en unknown
- 2000-03-16 IL IL14595500A patent/IL145955A0/xx unknown
- 2000-03-16 KR KR1020017014884A patent/KR20020010916A/ko not_active Withdrawn
- 2000-03-16 EE EEP200100611A patent/EE200100611A/xx unknown
- 2000-03-16 SK SK1660-2001A patent/SK16602001A3/sk unknown
- 2000-04-04 CO CO00024427A patent/CO5160295A1/es unknown
- 2000-04-04 HN HN2000000045A patent/HN2000000045A/es unknown
- 2000-04-25 PA PA20008494601A patent/PA8494601A1/es unknown
- 2000-05-17 TN TNTNSN00106A patent/TNSN00106A1/fr unknown
- 2000-05-17 MA MA25976A patent/MA26732A1/fr unknown
- 2000-05-17 DZ DZ000084A patent/DZ3041A1/fr active
- 2000-05-17 GT GT200000071A patent/GT200000071A/es unknown
- 2000-05-18 UY UY26148A patent/UY26148A1/es not_active Application Discontinuation
- 2000-05-19 PE PE2000000473A patent/PE20010157A1/es not_active Application Discontinuation
- 2000-05-19 AR ARP000102387A patent/AR022640A1/es not_active Application Discontinuation
-
2001
- 2001-10-26 IS IS6126A patent/IS6126A/is unknown
- 2001-11-20 NO NO20015651A patent/NO20015651L/no not_active Application Discontinuation
- 2001-11-20 ZA ZA200109555A patent/ZA200109555B/en unknown
- 2001-12-11 BG BG06208A patent/BG106208A/xx unknown
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