BG61898B1 - Използване на индолови производни като 5нт1-агонисти - Google Patents

Използване на индолови производни като 5нт1-агонисти Download PDF

Info

Publication number
BG61898B1
BG61898B1 BG100093A BG10009395A BG61898B1 BG 61898 B1 BG61898 B1 BG 61898B1 BG 100093 A BG100093 A BG 100093A BG 10009395 A BG10009395 A BG 10009395A BG 61898 B1 BG61898 B1 BG 61898B1
Authority
BG
Bulgaria
Prior art keywords
indole
ylmethyl
pharmaceutically acceptable
methylaminosulfonylmethyl
active
Prior art date
Application number
BG100093A
Other languages
Bulgarian (bg)
English (en)
Other versions
BG100093A (bg
Inventor
John E. Macor
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of BG100093A publication Critical patent/BG100093A/bg
Publication of BG61898B1 publication Critical patent/BG61898B1/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
BG100093A 1993-04-27 1995-10-25 Използване на индолови производни като 5нт1-агонисти BG61898B1 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5393093A 1993-04-27 1993-04-27
PCT/IB1994/000079 WO1994025023A1 (en) 1993-04-27 1994-04-26 Use of indole derivatives as 5ht1 antagonists

Publications (2)

Publication Number Publication Date
BG100093A BG100093A (bg) 1996-04-30
BG61898B1 true BG61898B1 (bg) 1998-09-30

Family

ID=21987528

Family Applications (1)

Application Number Title Priority Date Filing Date
BG100093A BG61898B1 (bg) 1993-04-27 1995-10-25 Използване на индолови производни като 5нт1-агонисти

Country Status (29)

Country Link
EP (1) EP0696194B1 (de)
JP (1) JP2922307B2 (de)
KR (1) KR960701636A (de)
CN (3) CN1515252A (de)
AP (1) AP486A (de)
AT (1) ATE222492T1 (de)
AU (1) AU689469B2 (de)
BG (1) BG61898B1 (de)
BR (1) BR9406435A (de)
CA (1) CA2161533C (de)
CO (1) CO4230093A1 (de)
CZ (1) CZ290416B6 (de)
DE (1) DE69431201T2 (de)
DK (1) DK0696194T3 (de)
ES (1) ES2180573T3 (de)
HU (1) HU222488B1 (de)
IL (1) IL109376A (de)
MX (1) MX9403088A (de)
NO (1) NO308236B1 (de)
NZ (1) NZ263614A (de)
OA (1) OA10189A (de)
PL (1) PL175156B1 (de)
PT (1) PT696194E (de)
RO (1) RO117760B1 (de)
RU (1) RU2132683C1 (de)
SG (1) SG43951A1 (de)
SK (1) SK283353B6 (de)
WO (1) WO1994025023A1 (de)
ZA (1) ZA942805B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578612A (en) * 1990-10-15 1996-11-26 Pfizer Inc. Indole derivatives
US5559246A (en) * 1990-10-15 1996-09-24 Pfizer Inc. Indole derivatives
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
US5559129A (en) * 1990-10-15 1996-09-24 Pfizer Inc Indole derivatives
US5607951A (en) * 1990-10-15 1997-03-04 Pfizer Inc Indole derivatives
KR100191973B1 (ko) * 1993-08-31 1999-06-15 디. 제이. 우드, 스피겔 알렌 제이 5-아릴인돌 유도체
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
DE69528288T2 (de) * 1994-10-12 2003-01-16 Pfizer Ltd., Sandwich Indolderivate zur behandlung von migräne
GB9424471D0 (en) * 1994-12-03 1995-01-18 Pfizer Ltd Treatment of emesis
GB9510223D0 (en) * 1995-05-20 1995-07-19 Pfizer Ltd Therapeutic agent
US5945118A (en) * 1995-09-29 1999-08-31 Pfizer Inc Indole derivative for the treatment of migraine
US5773015A (en) * 1996-11-27 1998-06-30 Elizabeth Arden Co., Division Of Conopco, Inc. Method for controlling skin oils and grease
GB9706089D0 (en) * 1997-03-24 1997-05-14 Scherer Ltd R P Pharmaceutical composition
US5994352A (en) * 1998-11-13 1999-11-30 Pfizer Inc. 5-arylindole derivatives
ES2199086B1 (es) * 2002-07-31 2005-06-01 Cepa Schwarz Pharma Sl Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
BR112022015379A2 (pt) * 2020-02-04 2022-09-27 Mindset Pharma Inc Derivados de 3-pirrolidino-indol como agentes psicodélicos serotonérgicos para o tratamento de distúrbios do snc

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL170330B1 (pl) * 1990-10-15 1996-11-29 Pfizer Sposób wytwarzania nowych pochodnych indolu PL PL PL PL PL PL
GB9102579D0 (en) * 1991-01-24 1991-03-27 Glaxo Group Ltd Compositions
GB9103770D0 (en) * 1991-02-22 1991-04-10 Glaxo Group Ltd Chemical compounds

Also Published As

Publication number Publication date
AP486A (en) 1996-04-16
HU222488B1 (hu) 2003-07-28
ES2180573T3 (es) 2003-02-16
DK0696194T3 (da) 2002-10-07
CN1509713A (zh) 2004-07-07
AU689469B2 (en) 1998-04-02
MX9403088A (es) 1997-02-28
RU2132683C1 (ru) 1999-07-10
KR960701636A (ko) 1996-03-28
AP9400633A0 (en) 1994-04-30
DE69431201D1 (de) 2002-09-26
CA2161533A1 (en) 1994-11-10
CZ9502802A3 (en) 1996-04-17
IL109376A (en) 2000-10-31
CN1515252A (zh) 2004-07-28
CN1121689A (zh) 1996-05-01
JPH08504829A (ja) 1996-05-28
CZ290416B6 (cs) 2002-07-17
AU6436094A (en) 1994-11-21
CA2161533C (en) 1998-08-04
ATE222492T1 (de) 2002-09-15
CO4230093A1 (es) 1995-10-19
PL175156B1 (pl) 1998-11-30
RO117760B1 (ro) 2002-07-30
HUT73670A (en) 1996-09-30
JP2922307B2 (ja) 1999-07-19
DE69431201T2 (de) 2002-12-05
PT696194E (pt) 2002-11-29
WO1994025023A1 (en) 1994-11-10
SG43951A1 (en) 1997-11-14
EP0696194A1 (de) 1996-02-14
ZA942805B (en) 1995-10-23
IL109376A0 (en) 1994-07-31
NO954287L (no) 1995-10-26
BR9406435A (pt) 1996-01-09
EP0696194B1 (de) 2002-08-21
NZ263614A (en) 1998-02-26
HU9503089D0 (en) 1995-12-28
OA10189A (en) 1996-12-18
NO954287D0 (no) 1995-10-26
SK283353B6 (sk) 2003-06-03
PL311266A1 (en) 1996-02-05
SK133295A3 (en) 1997-01-08
NO308236B1 (no) 2000-08-21
BG100093A (bg) 1996-04-30

Similar Documents

Publication Publication Date Title
BG61898B1 (bg) Използване на индолови производни като 5нт1-агонисти
EP0303507B1 (de) Indol-Derivate
JP4264850B2 (ja) 疼痛の処置のためのエピナスチンの使用
JP3721023B2 (ja) 性的機能障害の治療用のピラゾロピリミジノンｃＧＭＰＰＤＥ５阻害剤
JP3155008B2 (ja) セロトニンアゴニストおよびアンタゴニストとしての４−インドール誘導体
US4663326A (en) Pyrazolo[4,3-d]pyrimidine-5,7-(4H,6H)dione or -5-thione-7-one analogs
KR0183396B1 (ko) 3-아릴카르보닐-1-아미노알킬-1h-인돌류,이를 함유하는 항녹내장 조성물 및 이의 제조방법
CZ20011468A3 (cs) Farmaceutická kompozice a léčiva pro léčení migrény
JPH08333363A (ja) インドール誘導体
WO1994025023A9 (en) Use of indole derivatives as 5ht1 antagonists
PL172388B1 (pl) Pochodne indolu PL PL PL PL PL PL PL PL PL
WO1998027089A1 (en) 5-alkyl indole compounds as 5-ht1d-like ligands
JPH02167280A (ja) ラクタム誘導体
EP0804433B1 (de) Indolderivate zur behandlung von migräne
JPH01254665A (ja) ジヒドロピリジン抗アレルギーおよび抗炎症剤
US5945118A (en) Indole derivative for the treatment of migraine
US3829414A (en) 2-(2-indolyl)indolines
MXPA98003206A (en) Employment of epinastin for the treatment of dolo