BR0010568A - Composição farmacêutica, tecido estromal tri-dimensional, substância alimentìcia, suplemento nutricional, métodos para fabricar uma composição farmacêutica, para uma melhorada cicatrização de feridas ou queimaduras, para fabricar uma composição cosmética, para a correção de um defeito cosmético, para inibir ou reverter os efeitos deletérios para células em uma pessoa, para estimular o crescimento de cabelo, e para isolar colágeno - Google Patents

Composição farmacêutica, tecido estromal tri-dimensional, substância alimentìcia, suplemento nutricional, métodos para fabricar uma composição farmacêutica, para uma melhorada cicatrização de feridas ou queimaduras, para fabricar uma composição cosmética, para a correção de um defeito cosmético, para inibir ou reverter os efeitos deletérios para células em uma pessoa, para estimular o crescimento de cabelo, e para isolar colágeno

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Publication number
BR0010568A
BR0010568A BR0010568-6A BR0010568A BR0010568A BR 0010568 A BR0010568 A BR 0010568A BR 0010568 A BR0010568 A BR 0010568A BR 0010568 A BR0010568 A BR 0010568A
Authority
BR
Brazil
Prior art keywords
cells
medium
pharmaceutical composition
conditioned
cosmetic
Prior art date
Application number
BR0010568-6A
Other languages
English (en)
Inventor
Gail K Naughton
David L Horwitz
Mark A Applegate
Joan Zeltinger
Jonathan N Mansbridge
Andreas Kern
Lee K Landeen
Antony Ratcliffe
R Emmett Pinney
Original Assignee
Advanced Tissue Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23216124&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0010568(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Advanced Tissue Sciences Inc filed Critical Advanced Tissue Sciences Inc
Publication of BR0010568A publication Critical patent/BR0010568A/pt

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    • A—HUMAN NECESSITIES
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    • A61L2430/00—Materials or treatment for tissue regeneration
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    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/13—Coculture with; Conditioned medium produced by connective tissue cells; generic mesenchyme cells, e.g. so-called "embryonic fibroblasts"
    • C12N2502/1323—Adult fibroblasts

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Abstract

"COMPOSIçãO FARMACêUTICA TECIDO ESTROMAL TRI-DIMENSIONAL, SUBSTâNCIA ALIMENTìCIA, SUPLEMENTO NUTRICIONAL, MéTODOS PARA FABRICAR UMA COMPOSIçãO FARMACêUTICA PARA UMA MELHORADA CICATRIZAçãO DE FERIDAS OU QUEIMADURAS, PARA FABRICAR UMA COMPOSIçãO COSMéTICA, PARA A CORREçãO DE UM DEFEITO COSMéTICO, PARA INIBIR OU REVERTER OS EFEITOS DELETéRIOS PARA CéLULAS EM UMA PESSOA, PARA ESTIMULAR O CRESCIMENTO DE CABELO, E PARA ISOLAR COLáGENO". Novos produtos compreendendo meio de cultura de células condicionado e métodos de uso são descritos. As composições de meio condicionado de células da invenção podem ser compostas de qualquer meio definido ou não definido conhecido e podem ser condicionadas usando qualquer tipo de célula eucariótica. O meio pode ser condicionado por células estromais, células parenquimais, células indiferenciadas mesenquimais, células de reserva de fígado, células indiferenciadas neurais, células indiferenciadas pancreáticas, e/ou células indiferenciadas embriónicas. Adicionalmente, as células podem ser geneticamente modificadas. Uma construção de tecido tri-dimensional é preferida. Uma vez que o meio de célula da invenção é condicionado, ele pode ser usado em qualquer estado. As formas de realização físicas do meio condicionado incluem, mas não são limitadas a líquido ou sólido, congelado, liofilizado, ou seco em um pó. Adicionalmente, o meio é formulado com um veículo farmaceuticamente aceitável como um veículo para administração interna, aplicado diretamente a um item de alimento ou produto, formulado com uma pomada ou ung³ento para aplicações tópicas, ou por exemplo, feito em ou adicionado a uma cola cirúrgica para acelerar a cicatrização de suturas após procedimentos invasivos. Também o meio pode ser ainda processado para concentrar ou reduzir um ou mais fatores ou componentes contidos dentro do meio.
BR0010568-6A 1999-05-14 2000-05-12 Composição farmacêutica, tecido estromal tri-dimensional, substância alimentìcia, suplemento nutricional, métodos para fabricar uma composição farmacêutica, para uma melhorada cicatrização de feridas ou queimaduras, para fabricar uma composição cosmética, para a correção de um defeito cosmético, para inibir ou reverter os efeitos deletérios para células em uma pessoa, para estimular o crescimento de cabelo, e para isolar colágeno BR0010568A (pt)

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US09/313,538 US6372494B1 (en) 1999-05-14 1999-05-14 Methods of making conditioned cell culture medium compositions
PCT/US2000/013016 WO2000069449A2 (en) 1999-05-14 2000-05-12 Conditioned cell culture medium compositions and methods of use

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US7118746B1 (en) 2006-10-10
RU2280459C2 (ru) 2006-07-27
CN1198628C (zh) 2005-04-27
ES2254176T3 (es) 2006-06-16
US20130217069A1 (en) 2013-08-22
US20120230940A1 (en) 2012-09-13
US20130217129A1 (en) 2013-08-22
US8361485B2 (en) 2013-01-29
WO2000069449A3 (en) 2001-02-08
ZA200109381B (en) 2002-11-14
RU2001133453A (ru) 2005-01-20
EP1178812B1 (en) 2005-12-07
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US20170055561A1 (en) 2017-03-02
US20070077232A1 (en) 2007-04-05
US6372494B1 (en) 2002-04-16
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US20130209398A1 (en) 2013-08-15
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