BR0017157A - Derivados de 6-hidroxi-indazol para o tratamento de glaucoma - Google Patents

Derivados de 6-hidroxi-indazol para o tratamento de glaucoma

Info

Publication number
BR0017157A
BR0017157A BR0017157-3A BR0017157A BR0017157A BR 0017157 A BR0017157 A BR 0017157A BR 0017157 A BR0017157 A BR 0017157A BR 0017157 A BR0017157 A BR 0017157A
Authority
BR
Brazil
Prior art keywords
glaucoma
hydroxy
treatment
indazole derivatives
derivatives
Prior art date
Application number
BR0017157-3A
Other languages
English (en)
Portuguese (pt)
Inventor
Jesse A May
Anura P Dantanarayana
Zixia Feng
Original Assignee
Alcon Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Inc filed Critical Alcon Inc
Publication of BR0017157A publication Critical patent/BR0017157A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
    • C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR0017157-3A 2000-03-17 2000-11-14 Derivados de 6-hidroxi-indazol para o tratamento de glaucoma BR0017157A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19038000P 2000-03-17 2000-03-17
PCT/US2000/031247 WO2001070702A1 (en) 2000-03-17 2000-11-14 6-hydroxy-indazole derivatives for treating glaucoma

Publications (1)

Publication Number Publication Date
BR0017157A true BR0017157A (pt) 2002-11-26

Family

ID=22701093

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0017157-3A BR0017157A (pt) 2000-03-17 2000-11-14 Derivados de 6-hidroxi-indazol para o tratamento de glaucoma

Country Status (14)

Country Link
EP (1) EP1268438A1 (pl)
JP (1) JP2003528085A (pl)
KR (1) KR20030065304A (pl)
CN (1) CN1450994A (pl)
AR (1) AR032138A1 (pl)
AU (1) AU2001216072A1 (pl)
BR (1) BR0017157A (pl)
CA (1) CA2402403A1 (pl)
GC (1) GC0000155A (pl)
MX (1) MXPA02008547A (pl)
PL (1) PL358481A1 (pl)
TW (1) TWI221839B (pl)
WO (1) WO2001070702A1 (pl)
ZA (1) ZA200206851B (pl)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6960579B1 (en) 1998-05-19 2005-11-01 Alcon Manufacturing, Ltd. Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders
TW593302B (en) 2001-12-20 2004-06-21 Alcon Inc Novel benzodifuranimidazoline and benzofuranimidazoline derivatives and their use for the treatment of glaucoma
AU2002360819A1 (en) * 2001-12-28 2003-07-24 Bayer Corporation Cyclohexano- and cycloheptapyrazole derivative compounds, for use in diseases associated with the 5-ht2c receptor
US7196082B2 (en) 2002-11-08 2007-03-27 Merck & Co. Inc. Ophthalmic compositions for treating ocular hypertension
CN100384827C (zh) * 2002-11-08 2008-04-30 默克公司 用于治疗高眼压症的眼用组合物
WO2004043354A2 (en) 2002-11-08 2004-05-27 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
US7053085B2 (en) 2003-03-26 2006-05-30 Merck & Co. Inc. EP4 receptor agonist, compositions and methods thereof
EP1581209A4 (en) 2002-12-13 2009-03-11 Alcon Inc NEW BENZOPYRAN ANALOGUE AND ITS USE FOR THE TREATMENT OF GLAUKOM
JP2004262812A (ja) * 2003-02-28 2004-09-24 Rohto Pharmaceut Co Ltd 眼圧低下剤
CN1845914A (zh) 2003-09-02 2006-10-11 默克公司 用于治疗眼压过高的眼用组合物
AU2004272546B2 (en) 2003-09-04 2007-10-18 Merck Sharp & Dohme Corp. Ophthalmic compositions for treating ocular hypertension
AU2004271978B2 (en) 2003-09-04 2009-02-05 Merck & Co., Inc. Ophthalmic compositions for treating ocular hypertension
US7129257B1 (en) 2003-12-15 2006-10-31 Alcon, Inc. Pyrazolo[3,4- e]benzoxazoles for the treatment of glaucoma
US7338972B1 (en) 2003-12-15 2008-03-04 Alcon, Inc. Substituted 1-alkylamino-1H-indazoles for the treatment of glaucoma
AR046890A1 (es) 2003-12-15 2005-12-28 Alcon Inc [1,4] oxazino [2,3-g] indazoles sustituidos para el tratamiento del glaucoma.
CN1988903A (zh) 2004-07-20 2007-06-27 默克公司 用于治疗高眼压症的眼用组合物
ATE460415T1 (de) 2004-11-29 2010-03-15 Warner Lambert Co Therapeutische pyrazoloä3,4-büpyridine und - indazole
US7425572B2 (en) 2004-12-08 2008-09-16 Alcon, Inc. Use of dioxindoindazoles and dioxoloindazoles for treating glaucoma
CN101704785B (zh) * 2009-11-16 2012-02-29 东南大学 有机二羧酸和其盐及其制备方法
CN105884687B (zh) * 2016-04-14 2018-06-22 梯尔希（南京）药物研发有限公司 一种5-苄基苄达明的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9910590A (pt) * 1998-05-19 2001-01-23 Alcon Lab Inc Composto, processo para diminuir iop, para melhorar o fluxo sanguìneo para a extremidade do nervo óptico e a retina, e para tratar doenças retinais, composições para diminuir iop, para melhorar o fluxo sanguìneo para a extremidade do nervo óptico e a retina, e para tratar doenças retinais, processo e composição para prover neuroproteção para a extremidade do nervo óptico ou a retina, e, processo para tratar pessoas sofrendo de distúrbios do sono, depressão, esquizofrenia, ansiedade, distúrbios rìtmicos circadianos e hipertensão centralmente e perifericamente mediada
ES2204067T3 (es) * 1998-05-26 2004-04-16 Pfizer Products Inc. Medicamento para el tratamiento del glaucoma y de la retinopatia isquemica.
GB9819032D0 (en) * 1998-09-01 1998-10-28 Cerebrus Ltd Chemical compounds IV
DK1112106T3 (da) * 1998-09-18 2005-12-12 Alcon Mfg Ltd Serotonerge 5HT2-agonister til behandling af glaukom
GB9820767D0 (en) * 1998-09-23 1998-11-18 Cerebrus Ltd Chemical compounds VIII

Also Published As

Publication number Publication date
CA2402403A1 (en) 2001-09-27
JP2003528085A (ja) 2003-09-24
MXPA02008547A (es) 2003-03-12
PL358481A1 (pl) 2004-08-09
TWI221839B (en) 2004-10-11
AU2001216072A1 (en) 2001-10-03
ZA200206851B (en) 2003-10-21
GC0000155A (en) 2005-06-29
CN1450994A (zh) 2003-10-22
EP1268438A1 (en) 2003-01-02
AR032138A1 (es) 2003-10-29
WO2001070702A1 (en) 2001-09-27
KR20030065304A (ko) 2003-08-06

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Legal Events

Date Code Title Description
B08F Application fees: application dismissed [chapter 8.6 patent gazette]

Free format text: REFERENTE A 6A E 7A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1962 DE 12/08/2008.