BRPI0414512B8 - composição para reproduzir imagens de um pâncreas e uso desta - Google Patents

composição para reproduzir imagens de um pâncreas e uso desta

Info

Publication number
BRPI0414512B8
BRPI0414512B8 BRPI0414512A BRPI0414512A BRPI0414512B8 BR PI0414512 B8 BRPI0414512 B8 BR PI0414512B8 BR PI0414512 A BRPI0414512 A BR PI0414512A BR PI0414512 A BRPI0414512 A BR PI0414512A BR PI0414512 B8 BRPI0414512 B8 BR PI0414512B8
Authority
BR
Brazil
Prior art keywords
pancreas
composition
reproduce images
compositions
images
Prior art date
Application number
BRPI0414512A
Other languages
English (en)
Inventor
Azhdarinia Ali
Oh Chang-Sok
J Yang David
Yu Dong-Fang
Bryant Jerry
Kohanim Saady
Original Assignee
Board Of Regentes The Univ Of Texas System
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Board Of Regentes The Univ Of Texas System filed Critical Board Of Regentes The Univ Of Texas System
Publication of BRPI0414512A publication Critical patent/BRPI0414512A/pt
Publication of BRPI0414512B1 publication Critical patent/BRPI0414512B1/pt
Publication of BRPI0414512B8 publication Critical patent/BRPI0414512B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)

Abstract

reprodução de imagens e terapia de células beta pancreáticas, direcionadas por um mecanismo a presente invenção refere-se a composições para reproduzir imagens de células beta, sendo que as composições compreendem conjugados de quelante/agente antidiabético, e opcionalmente, metais quelados.
BRPI0414512A 2003-09-17 2004-09-16 composição para reproduzir imagens de um pâncreas e uso desta BRPI0414512B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50368303P 2003-09-17 2003-09-17
US60/503.683 2003-09-17
PCT/US2004/030374 WO2005027981A1 (en) 2003-09-17 2004-09-16 Mechanism-based targeted pancreatic beta cell imaging and therapy

Publications (3)

Publication Number Publication Date
BRPI0414512A BRPI0414512A (pt) 2006-11-07
BRPI0414512B1 BRPI0414512B1 (pt) 2020-11-17
BRPI0414512B8 true BRPI0414512B8 (pt) 2021-05-25

Family

ID=34375381

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414512A BRPI0414512B8 (pt) 2003-09-17 2004-09-16 composição para reproduzir imagens de um pâncreas e uso desta

Country Status (15)

Country Link
US (2) US7611693B2 (pt)
EP (2) EP1675625B1 (pt)
JP (3) JP5395327B2 (pt)
KR (2) KR101152729B1 (pt)
CN (1) CN1867363B (pt)
AU (1) AU2004273911B2 (pt)
BR (1) BRPI0414512B8 (pt)
CA (1) CA2539384C (pt)
DK (1) DK1675625T3 (pt)
ES (1) ES2403378T3 (pt)
IL (1) IL174374A (pt)
NO (1) NO336658B1 (pt)
PL (1) PL1675625T3 (pt)
PT (1) PT1675625E (pt)
WO (1) WO2005027981A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0414512B8 (pt) * 2003-09-17 2021-05-25 Board Of Regentes The Univ Of Texas System composição para reproduzir imagens de um pâncreas e uso desta
WO2006104401A1 (en) * 2005-03-26 2006-10-05 Protemix Corporation Limited Copper antagonist compositions
CA2623794A1 (en) * 2005-06-29 2007-01-11 The Trustees Of Columbia University In The City Of New York Use of dtbz for imaging endocrine pancreas and beta cell mass in type 1 diabetes
WO2008038304A2 (en) * 2006-09-26 2008-04-03 Jegannathan Srinivas Therapeutical formulation comprising an alpha-glucosidase inhibitor and a nitric oxide scavenger.
WO2008038302A2 (en) * 2006-09-26 2008-04-03 Jegannathan Srinivas Therapeutic formulation comprising a sulfonylurea, metformin and a nitric oxide scavenger.
KR20100127845A (ko) 2008-03-24 2010-12-06 더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 심근 질환의 영상-유도된 치료: 조성물, 제조 및 적용
WO2011013703A1 (ja) * 2009-07-31 2011-02-03 独立行政法人理化学研究所 膵臓内分泌細胞用指示薬、及びその利用

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2951135A1 (de) 1979-12-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung
JPS57102820A (en) 1980-12-19 1982-06-26 Nippon Mejifuijitsukusu Kk Agent for radiodiagnosis
JPS5944329A (ja) 1982-09-07 1984-03-12 Nippon Mejifuijitsukusu Kk 新規な放射性診断剤
JPS59193833A (ja) 1983-04-19 1984-11-02 Nippon Mejifuijitsukusu Kk 新規な二官能配位子化合物含有放射性診断剤
US4732864A (en) 1983-10-06 1988-03-22 E. I. Du Pont De Nemours And Company Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules
JPS6354321A (ja) 1985-03-27 1988-03-08 Ajinomoto Co Inc 血糖降下剤
JPH01186899A (ja) 1988-01-18 1989-07-26 Nippon Mejifuijitsukusu Kk 膜透過性を有するＴｃ−９９ｍ単核錯体
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
US5094837A (en) 1990-01-22 1992-03-10 Wayne State University Method for use of magnetic resonance imaging to image pancreas using secretin
US4994258A (en) 1990-03-05 1991-02-19 Merck & Co., Inc. Gamma emitting, CCK-A antagonists for pancreatic imaging
FR2661187B1 (fr) 1990-04-20 1994-08-05 Inst Nat Sante Rech Med Proteine associee a la pancreatite aiguue. moyens pour le diagnostic de la pancreatite aiguue.
JPH05186372A (ja) 1991-07-18 1993-07-27 Green Cross Corp:The 脂肪乳剤及びｍｒｉ診断用造影剤
US5463116A (en) 1991-07-30 1995-10-31 Ajinomoto Co., Inc. Crystals of N- (trans-4-isopropylcyclohexlycarbonyl)-D-phenylalanine and methods for preparing them
JP3465247B2 (ja) 1992-12-28 2003-11-10 アベンティス ファーマ株式会社 動脈硬化症の予防および治療剤
US5656600A (en) * 1993-03-25 1997-08-12 Corvas International, Inc. α-ketoamide derivatives as inhibitors of thrombosis
US5879657A (en) * 1993-03-30 1999-03-09 The Dupont Merck Pharmaceutical Company Radiolabeled platelet GPIIb/IIIa receptor antagonists as imaging agents for the diagnosis of thromboembolic disorders
DE4336159A1 (de) 1993-10-22 1995-04-27 Kurt Heinz Prof Dr Bauer Hochwirksame, den Wirkstoff schnell oder kontrolliert freisetzende Zubereitungsformen von Sulfonylharnstoffen und Verfahren zu deren Herstellung
US5763200A (en) * 1995-05-12 1998-06-09 Biomeasure, Incorporated Inhibition of amylin release
ATE253381T1 (de) 1997-02-03 2003-11-15 Mallinckrodt Inc Verfahren zur detektion und lokalisation maligner meschlicher tumore des pankreas
EP1080209A2 (en) 1998-10-21 2001-03-07 Arch Development Corporation Methods of treatment of type 2 diabetes
US6358491B1 (en) * 1999-08-27 2002-03-19 Berlex Laboratories, Inc. Somatostatin analogs
EP1616561B1 (en) * 1999-12-28 2008-06-25 Ajinomoto Co., Inc. Antidiabetic preparation for oral administration
CA2403442A1 (en) * 2000-03-17 2002-09-17 Ajinomoto Co., Inc. Use of nateglinide alone or in combination for the treatment or prevention of diabetic complications
AU2001285145A1 (en) 2000-08-21 2002-03-04 Millennium Pharmaceuticals, Inc. Human abc transporter family member and uses thereof
WO2002088378A2 (en) 2001-04-13 2002-11-07 Millennium Pharmaceuticals, Inc. 66784, a novel human potassium channel and uses therefor
BRPI0414512B8 (pt) * 2003-09-17 2021-05-25 Board Of Regentes The Univ Of Texas System composição para reproduzir imagens de um pâncreas e uso desta

Also Published As

Publication number Publication date
HK1094312A1 (en) 2007-03-30
KR20060104984A (ko) 2006-10-09
NO336658B1 (no) 2015-10-12
US20100278731A1 (en) 2010-11-04
AU2004273911B2 (en) 2010-04-15
JP2007505915A (ja) 2007-03-15
JP2015078223A (ja) 2015-04-23
NO20061645L (no) 2006-04-11
CN1867363B (zh) 2010-05-12
US20050100506A1 (en) 2005-05-12
JP5395327B2 (ja) 2014-01-22
KR20110119813A (ko) 2011-11-02
WO2005027981A1 (en) 2005-03-31
US7611693B2 (en) 2009-11-03
JP2011052016A (ja) 2011-03-17
IL174374A0 (en) 2006-08-01
IL174374A (en) 2011-12-29
ES2403378T3 (es) 2013-05-17
CN1867363A (zh) 2006-11-22
BRPI0414512A (pt) 2006-11-07
CA2539384A1 (en) 2005-03-31
EP1675625A4 (en) 2009-07-15
EP2474328A2 (en) 2012-07-11
EP1675625B1 (en) 2013-02-20
EP2474328A3 (en) 2012-07-18
AU2004273911A1 (en) 2005-03-31
KR101152729B1 (ko) 2012-06-15
CA2539384C (en) 2012-08-28
BRPI0414512B1 (pt) 2020-11-17
DK1675625T3 (da) 2013-05-13
EP1675625A1 (en) 2006-07-05
PL1675625T3 (pl) 2013-08-30
PT1675625E (pt) 2013-05-23

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 17/11/2020, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/09/2004 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF