BRPI0517227A - forma de dosagem oral de liberação prolongada do ácido 1-{[alfa-isobutanoiloxietoxi)carbonil]amino metil}-1-cicloexano acético, e, método de tratamento de uma doença ou condição - Google Patents

forma de dosagem oral de liberação prolongada do ácido 1-{[alfa-isobutanoiloxietoxi)carbonil]amino metil}-1-cicloexano acético, e, método de tratamento de uma doença ou condição

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Publication number
BRPI0517227A
BRPI0517227A BRPI0517227-6A BRPI0517227A BRPI0517227A BR PI0517227 A BRPI0517227 A BR PI0517227A BR PI0517227 A BRPI0517227 A BR PI0517227A BR PI0517227 A BRPI0517227 A BR PI0517227A
Authority
BR
Brazil
Prior art keywords
isobutanoyloxyethoxy
alpha
disease
condition
acetic acid
Prior art date
Application number
BRPI0517227-6A
Other languages
English (en)
Inventor
Kenneth C Cundy
Manshiu Leung
Balaji V Kadri
Paul E Stach
Srikonda Sastry
Original Assignee
Xenoport Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35929688&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0517227(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Xenoport Inc filed Critical Xenoport Inc
Publication of BRPI0517227A publication Critical patent/BRPI0517227A/pt
Publication of BRPI0517227B1 publication Critical patent/BRPI0517227B1/pt
Publication of BRPI0517227B8 publication Critical patent/BRPI0517227B8/pt

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    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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  • Health & Medical Sciences (AREA)
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Abstract

FORMA DE DOSAGEM ORAL DE LIBERAçãO PROLONGADA DO áCIDO 1- { ¢ALFA-ISOBUTANOILOXIETOXI)CARIBONIL!AMINO METIL}-1-CICLOEXANO ACéTICO, E, MéTODO DE TRATAMENTO DE UMA DOENçA OU CONDIçãO. São apresentadas formas de dosagem oral de liberação prolongada da pró-droga gabapentina, ácido 1 {¢(<244> isobutanoiloxietoxi)carbonil!amino metil}- 1 -cicloexano acético. As formas de dosagens são úteis para o tratamento ou prevenção de doenças e distúrbios para os quais a gabapentina é terapeuticamente eficaz.
BRPI0517227A 2004-11-04 2005-11-03 comprimido oral de liberação prolongada do ácido 1-{[alfa-isobutanoiloxietoxi)carbonil]amino metil}-1-cicloexano acético, e, uso do comprimido BRPI0517227B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62573704P 2004-11-04 2004-11-04
PCT/US2005/040127 WO2006050514A1 (en) 2004-11-04 2005-11-03 Gabapentin prodrug sustained release oral dosage forms

Publications (3)

Publication Number Publication Date
BRPI0517227A true BRPI0517227A (pt) 2008-10-14
BRPI0517227B1 BRPI0517227B1 (pt) 2019-09-03
BRPI0517227B8 BRPI0517227B8 (pt) 2021-05-25

Family

ID=35929688

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0517227A BRPI0517227B8 (pt) 2004-11-04 2005-11-03 comprimido oral de liberação prolongada do ácido 1-{[alfa-isobutanoiloxietoxi)carbonil]amino metil}-1-cicloexano acético, e, uso do comprimido

Country Status (16)

Country Link
US (8) US8795725B2 (pt)
EP (1) EP1811986B1 (pt)
JP (2) JP2008518971A (pt)
KR (1) KR101228399B1 (pt)
CN (2) CN102429882B (pt)
AU (1) AU2005301970B2 (pt)
BR (1) BRPI0517227B8 (pt)
CA (1) CA2584338C (pt)
IL (1) IL182964A0 (pt)
MX (1) MX2007005306A (pt)
NO (1) NO338688B1 (pt)
NZ (1) NZ554737A (pt)
RU (1) RU2440112C2 (pt)
TW (1) TWI377938B (pt)
WO (1) WO2006050514A1 (pt)
ZA (1) ZA200703571B (pt)

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CA2537837A1 (en) * 2003-09-11 2005-03-24 Xenoport, Inc. Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
MXPA06003043A (es) * 2003-09-17 2006-05-31 Xenoport Inc Tratamiento o prevencion del sindrome piernas inquietas utilizando prodrogas de analogos gaba.
WO2005037784A2 (en) * 2003-10-14 2005-04-28 Xenoport, Inc. Crystalline form of gamma-aminobutyric acid analog
EP1811986B1 (en) * 2004-11-04 2014-03-26 XenoPort, Inc. Gabapentin prodrug sustained release oral dosage forms
WO2007002013A2 (en) * 2005-06-20 2007-01-04 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
US20070049627A1 (en) * 2005-08-23 2007-03-01 Tran Pierre V Treating vulvodynia using prodrugs of GABA analogs
WO2007027476A2 (en) * 2005-08-26 2007-03-08 Xenoport, Inc. Treating premature ejaculation using gabapentin and pregabalin prodrugs
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WO2010101115A1 (ja) 2009-03-02 2010-09-10 アステラス製薬株式会社 固形製剤の包装体
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AU2010221167B2 (en) * 2009-03-06 2014-04-03 Xenoport, Inc. Oral dosage forms having a high loading of a gabapentin prodrug
US20110060040A1 (en) * 2009-09-04 2011-03-10 Xenoport, Inc. Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
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