BRPI0911161A2 - derivado de piridazinona - Google Patents

derivado de piridazinona

Info

Publication number
BRPI0911161A2
BRPI0911161A2 BRPI0911161A BRPI0911161A BRPI0911161A2 BR PI0911161 A2 BRPI0911161 A2 BR PI0911161A2 BR PI0911161 A BRPI0911161 A BR PI0911161A BR PI0911161 A BRPI0911161 A BR PI0911161A BR PI0911161 A2 BRPI0911161 A2 BR PI0911161A2
Authority
BR
Brazil
Prior art keywords
pyridazinone derivative
pyridazinone
derivative
Prior art date
Application number
BRPI0911161A
Other languages
English (en)
Inventor
Andree Blaukat
Dieter Dorsch
Frank Stieber
Oliver Schadt
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of BRPI0911161A2 publication Critical patent/BRPI0911161A2/pt
Publication of BRPI0911161B1 publication Critical patent/BRPI0911161B1/pt
Publication of BRPI0911161B8 publication Critical patent/BRPI0911161B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BRPI0911161A 2008-04-21 2009-03-24 derivados de piridazinona e seu processo de preparação BRPI0911161B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE102008019907A DE102008019907A1 (de) 2008-04-21 2008-04-21 Pyridazinonderivate
DE102008019907.9 2008-04-21
PCT/EP2009/002137 WO2009129905A1 (de) 2008-04-21 2009-03-24 Pyridazinonderivate

Publications (3)

Publication Number Publication Date
BRPI0911161A2 true BRPI0911161A2 (pt) 2015-10-06
BRPI0911161B1 BRPI0911161B1 (pt) 2020-02-11
BRPI0911161B8 BRPI0911161B8 (pt) 2021-05-25

Family

ID=40639931

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0911161A BRPI0911161B8 (pt) 2008-04-21 2009-03-24 derivados de piridazinona e seu processo de preparação

Country Status (22)

Country Link
US (1) US8604036B2 (pt)
EP (1) EP2280962B1 (pt)
JP (1) JP5576358B2 (pt)
KR (1) KR20100137564A (pt)
CN (1) CN102015694A (pt)
AR (1) AR071208A1 (pt)
AU (1) AU2009240346B2 (pt)
BR (1) BRPI0911161B8 (pt)
CA (1) CA2721858C (pt)
CY (1) CY1113443T1 (pt)
DE (1) DE102008019907A1 (pt)
DK (1) DK2280962T5 (pt)
EA (1) EA018362B1 (pt)
ES (1) ES2394147T3 (pt)
HR (1) HRP20120884T1 (pt)
IL (1) IL208336A (pt)
MX (1) MX2010011454A (pt)
PL (1) PL2280962T3 (pt)
PT (1) PT2280962E (pt)
SI (1) SI2280962T1 (pt)
WO (1) WO2009129905A1 (pt)
ZA (1) ZA201008330B (pt)

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DE102008019907A1 (de) 2008-04-21 2009-10-22 Merck Patent Gmbh Pyridazinonderivate
DE102008028905A1 (de) * 2008-06-18 2009-12-24 Merck Patent Gmbh 3-(3-Pyrimidin-2-yl-benzyl)-[1,2,4]triazolo[4,3-b]pyridazinderivate
DE102008037790A1 (de) * 2008-08-14 2010-02-18 Merck Patent Gmbh Bicyclische Triazolderivate
SI2361250T1 (sl) 2008-12-22 2013-12-31 Merck Patent Gmbh Nove polimorfne oblike 6-(1-metil-1h-pirazol-4-il)-2-(3-(5-(2-morfolin-4-il-etoksi)-pirimidin- 2-il)-benzil)-2h-piridazin-3-on dihidrogenfosfata in postopki za proizvodnjo le-tega
CN102532126B (zh) * 2012-02-10 2014-06-18 贵州大学 2-取代-4-氯-5-[5-取代胺基-2-(1,3,4-噻二唑基)-巯基]-3(2h)-哒嗪酮类衍生物及其制备方法和用途
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US11180480B2 (en) 2017-10-17 2021-11-23 Sensorion Synthesis of 4-aminopyrimidine compounds
CN108752322A (zh) * 2018-09-12 2018-11-06 广州新民培林医药科技有限公司 一种新型Tepotinib衍生物和制备方法及其在抗肿瘤药物中的应用
ES2958954T3 (es) 2018-11-06 2024-02-16 Edgewise Therapeutics Inc Compuestos de piridazinona y usos de los mismos
WO2020097258A1 (en) 2018-11-06 2020-05-14 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
EP3877052B1 (en) 2018-11-06 2023-08-16 Edgewise Therapeutics, Inc. Pyridazinone compounds and uses thereof
CA3121202A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
CN114502551B (zh) 2019-11-01 2023-08-22 优迈特株式会社 含氟嘧啶化合物及其制备方法

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Also Published As

Publication number Publication date
MX2010011454A (es) 2010-12-21
IL208336A (en) 2016-07-31
IL208336A0 (en) 2010-12-30
CA2721858C (en) 2016-07-19
EP2280962B1 (de) 2012-10-03
DK2280962T3 (da) 2012-11-19
BRPI0911161B8 (pt) 2021-05-25
US20110034474A1 (en) 2011-02-10
CY1113443T1 (el) 2016-06-22
WO2009129905A1 (de) 2009-10-29
ES2394147T3 (es) 2013-01-22
EA201001648A1 (ru) 2011-06-30
PT2280962E (pt) 2012-12-17
SI2280962T1 (sl) 2013-01-31
EA018362B1 (ru) 2013-07-30
CN102015694A (zh) 2011-04-13
KR20100137564A (ko) 2010-12-30
HRP20120884T1 (hr) 2012-11-30
AR071208A1 (es) 2010-06-02
DK2280962T5 (da) 2013-09-16
EP2280962A1 (de) 2011-02-09
US8604036B2 (en) 2013-12-10
CA2721858A1 (en) 2009-10-29
DE102008019907A1 (de) 2009-10-22
AU2009240346A1 (en) 2009-10-29
PL2280962T3 (pl) 2013-02-28
JP5576358B2 (ja) 2014-08-20
JP2011518202A (ja) 2011-06-23
AU2009240346B2 (en) 2013-10-10
BRPI0911161B1 (pt) 2020-02-11
ZA201008330B (en) 2011-09-28

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Legal Events

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B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
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Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B06T Formal requirements before examination [chapter 6.20 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 24/03/2009 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

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B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2767 DE 16-01-2024 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.