BRPI0924997A2 - Método para preparar um composto de éster do ácido aril-2-tetrazoil etil carbâmico. - Google Patents
Método para preparar um composto de éster do ácido aril-2-tetrazoil etil carbâmico.Info
- Publication number
- BRPI0924997A2 BRPI0924997A2 BRPI0924997-4A BRPI0924997A BRPI0924997A2 BR PI0924997 A2 BRPI0924997 A2 BR PI0924997A2 BR PI0924997 A BRPI0924997 A BR PI0924997A BR PI0924997 A2 BRPI0924997 A2 BR PI0924997A2
- Authority
- BR
- Brazil
- Prior art keywords
- tetrazoyl
- aryl
- preparing
- acid ester
- carbamic acid
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title 1
- KWBIXTIBYFUAGV-UHFFFAOYSA-N ethylcarbamic acid Chemical compound CCNC(O)=O KWBIXTIBYFUAGV-UHFFFAOYSA-N 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
- C07D257/06—Five-membered rings with nitrogen atoms directly attached to the ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/10—Nitrogen as only ring hetero atom
- C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR10-2009-0055576 | 2009-06-22 | ||
| KR20090055576 | 2009-06-22 | ||
| PCT/KR2009/005906 WO2010150946A1 (en) | 2009-06-22 | 2009-10-14 | Method for preparation of carbamic acid (r)-1-aryl-2-tetrazolyl-ethyl ester |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BRPI0924997A2 true BRPI0924997A2 (pt) | 2015-08-11 |
| BRPI0924997B1 BRPI0924997B1 (pt) | 2024-01-16 |
Family
ID=43354688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BRPI0924997-4A BRPI0924997B1 (pt) | 2009-06-22 | 2009-10-14 | Método para preparar um composto de éster do ácido 1-aril-2- tetrazoil etil carbâmico |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US8501436B2 (pt) |
| EP (1) | EP2445890B1 (pt) |
| JP (1) | JP5683580B2 (pt) |
| KR (1) | KR101708433B1 (pt) |
| CN (1) | CN102803233B (pt) |
| AU (1) | AU2009348523B2 (pt) |
| BR (1) | BRPI0924997B1 (pt) |
| CA (1) | CA2765566C (pt) |
| CL (1) | CL2011003244A1 (pt) |
| ES (1) | ES2541590T3 (pt) |
| IL (1) | IL216786A (pt) |
| MX (1) | MX2011013982A (pt) |
| MY (1) | MY155662A (pt) |
| PL (1) | PL2445890T3 (pt) |
| RU (1) | RU2508290C2 (pt) |
| WO (1) | WO2010150946A1 (pt) |
| ZA (1) | ZA201109362B (pt) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US8404461B2 (en) * | 2009-10-15 | 2013-03-26 | SK Biopharmaceutical Co. Ltd. | Method for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl ester |
| KR102489052B1 (ko) * | 2016-05-19 | 2023-01-16 | 에스케이바이오팜 주식회사 | 섬유근육통 또는 섬유근육통의 연관된 기능적 증후군을 예방 또는 치료하기 위한 카바메이트 화합물의 용도 |
| KR102421006B1 (ko) * | 2016-05-19 | 2022-07-14 | 에스케이바이오팜 주식회사 | 두통의 예방학적 치료를 위한 카바메이트 화합물의 용도 |
| KR102421013B1 (ko) * | 2016-05-19 | 2022-07-14 | 에스케이바이오팜 주식회사 | 삼차신경통을 예방 또는 치료하기 위한 카바메이트 화합물의 용도 |
| PL3556349T3 (pl) | 2016-12-14 | 2022-04-11 | Sk Biopharmaceuticals Co., Ltd. | Preparat ciekły do podawania pozajelitowego zawierający związek karbaminianowy |
| JP7086076B2 (ja) | 2016-12-14 | 2022-06-17 | エスケー バイオファーマスティカルズ カンパニー リミテッド | 振戦又は振戦症候群の予防、軽減又は治療のためのカルバメート化合物の使用 |
| MY199104A (en) | 2016-12-14 | 2023-10-13 | Sk Biopharmaceuticals Co Ltd | Use of carbamate compounds for prevention, alleviation or treatment of bipolar disorder |
| ES2975254T3 (es) | 2016-12-14 | 2024-07-04 | Sk Biopharmaceuticals Co Ltd | Uso de compuestos de carbamato para la prevención, alivio o tratamiento del prurito |
| JP7090616B2 (ja) | 2016-12-14 | 2022-06-24 | エスケー バイオファーマスティカルズ カンパニー リミテッド | カルバメート化合物を含む口腔内崩壊錠 |
| WO2018111006A1 (ko) | 2016-12-14 | 2018-06-21 | 에스케이바이오팜 주식회사 | 탈수초성 질환의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도 |
| US11406620B2 (en) | 2017-11-14 | 2022-08-09 | Sk Biopharmaceuticals Co., Ltd. | Use of carbamate compound for preventing or treating diseases associated with increase in late sodium current |
| WO2019098630A1 (ko) | 2017-11-14 | 2019-05-23 | 에스케이바이오팜 주식회사 | 취약 x 증후군, 엔젤만 증후군 또는 렛 증후군을 포함하는 발달 장애의 경감 또는 치료를 위한 카바메이트 화합물의 용도 |
| EP4545140A3 (en) | 2017-11-14 | 2025-07-09 | SK Biopharmaceuticals Co., Ltd. | Blend containing carbamate compound for prevention, mitigation, or treatment of schizophrenia |
| US11666554B2 (en) | 2017-11-14 | 2023-06-06 | Sk Biopharmaceuticals Co., Ltd. | Use of a carbamate compound to prevent, alleviate or treat visceralgia or pain arising from visceral disease |
| JP7258901B2 (ja) * | 2017-11-14 | 2023-04-17 | エスケー バイオファーマスティカルズ カンパニー リミテッド | 欠神発作又は欠神発作を示すてんかんの予防、軽減又は治療のためのカルバメート化合物の使用 |
| KR102900174B1 (ko) | 2017-11-14 | 2025-12-16 | 에스케이바이오팜 주식회사 | 근긴장증의 예방, 경감 또는 치료를 위한 카바메이트 화합물의 용도 |
| CA3113052A1 (en) | 2018-09-21 | 2020-03-26 | Sk Biopharmaceuticals Co., Ltd. | Use of carbamate compound for prevention, alleviation, or treatment of status epilepticus |
| JP7408643B2 (ja) * | 2018-09-21 | 2024-01-05 | エスケー バイオファーマスティカルズ カンパニー リミテッド | カルバメート化合物及びそれを含む製剤の急性ストレス障害又は心的外傷後ストレス障害の予防、軽減又は治療のための使用 |
| TWI837197B (zh) | 2018-10-19 | 2024-04-01 | 南韓商愛思開生物製藥股份有限公司 | 胺基甲酸酯化合物於預防、緩解或治療糖尿病周邊神經病變或化療誘發的周邊神經病變的用途 |
| MX2022004740A (es) * | 2019-10-24 | 2022-05-16 | Sk Biopharmaceuticals Co Ltd | Metodo para preparar aril 2-tetrazol-2-il cetona con selectividad mejorada. |
| US10611737B1 (en) * | 2019-10-24 | 2020-04-07 | Sk Biopharmaceuticals Co., Ltd. | Method for preparing aryl 2-tetrazol-2-yl ketone with improved selectivity |
| KR20220104746A (ko) | 2019-11-22 | 2022-07-26 | 에스케이바이오팜 주식회사 | 카바메이트 화합물을 포함하는 경구용 약제학적 조성물 및 그 제조방법 |
| CN110982757B (zh) * | 2019-12-30 | 2021-04-06 | 浙江工业大学 | 阴沟肠杆菌zjph1903及应用 |
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| CN111778198B (zh) * | 2020-08-18 | 2021-12-10 | 杭州医学院 | 一种藤黄细球菌hmc01及其在不对称还原制备手性醇中的应用 |
| AR125970A1 (es) | 2021-05-28 | 2023-08-30 | Sk Biopharmaceuticals Co Ltd | Formulaciones de suspensión acuosa para administración oral que comprenden un compuesto de carbamato |
| WO2023152711A1 (en) * | 2022-02-12 | 2023-08-17 | Metrochem Api Pvt Ltd | Process for the preparation of cenobamate and intermediates thereof |
| ES2931000B2 (es) * | 2022-07-14 | 2023-07-07 | Univ Madrid Complutense | Proceso para la preparación de cenobamato |
| CN117736157B (zh) * | 2022-09-13 | 2025-08-19 | 江苏恩华药业股份有限公司 | 一种四唑取代的苯乙酮化合物的制备方法 |
| CN115716810B (zh) * | 2022-11-15 | 2026-02-13 | 江苏艾立康医药科技有限公司 | 一种西诺氨酯的晶体形式及其制备方法 |
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-
2009
- 2009-10-14 WO PCT/KR2009/005906 patent/WO2010150946A1/en not_active Ceased
- 2009-10-14 US US12/578,709 patent/US8501436B2/en active Active
- 2009-10-14 AU AU2009348523A patent/AU2009348523B2/en active Active
- 2009-10-14 BR BRPI0924997-4A patent/BRPI0924997B1/pt active IP Right Grant
- 2009-10-14 MX MX2011013982A patent/MX2011013982A/es active IP Right Grant
- 2009-10-14 CA CA2765566A patent/CA2765566C/en active Active
- 2009-10-14 EP EP20090846577 patent/EP2445890B1/en active Active
- 2009-10-14 CN CN200980160004.3A patent/CN102803233B/zh active Active
- 2009-10-14 PL PL09846577T patent/PL2445890T3/pl unknown
- 2009-10-14 MY MYPI2011006091A patent/MY155662A/en unknown
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- 2009-10-14 RU RU2012102051/04A patent/RU2508290C2/ru active
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Also Published As
| Publication number | Publication date |
|---|---|
| CN102803233A (zh) | 2012-11-28 |
| JP2012530513A (ja) | 2012-12-06 |
| RU2508290C2 (ru) | 2014-02-27 |
| KR101708433B1 (ko) | 2017-02-22 |
| IL216786A (en) | 2014-09-30 |
| EP2445890B1 (en) | 2015-05-06 |
| WO2010150946A1 (en) | 2010-12-29 |
| KR20100137389A (ko) | 2010-12-30 |
| CA2765566A1 (en) | 2010-12-29 |
| US20100323410A1 (en) | 2010-12-23 |
| CN102803233B (zh) | 2017-03-01 |
| AU2009348523A1 (en) | 2012-01-12 |
| IL216786A0 (en) | 2012-02-29 |
| PL2445890T3 (pl) | 2016-02-29 |
| MY155662A (en) | 2015-11-13 |
| CL2011003244A1 (es) | 2012-08-10 |
| EP2445890A1 (en) | 2012-05-02 |
| ZA201109362B (en) | 2012-08-29 |
| ES2541590T3 (es) | 2015-07-22 |
| JP5683580B2 (ja) | 2015-03-11 |
| CA2765566C (en) | 2016-04-12 |
| MX2011013982A (es) | 2013-01-29 |
| AU2009348523B2 (en) | 2015-02-26 |
| US8501436B2 (en) | 2013-08-06 |
| BRPI0924997B1 (pt) | 2024-01-16 |
| EP2445890A4 (en) | 2012-11-21 |
| RU2012102051A (ru) | 2013-07-27 |
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